| scholarly article | Q13442814 |
| P50 | author | Xiao Yang | Q52359342 |
| P2093 | author name string | X. Yang | |
| L. Chen | |||
| A. B. Roberts | |||
| C. Deng | |||
| H. Gu | |||
| J. J. Letterio | |||
| R. Hayman | |||
| R. J. Lechleider | |||
| P2860 | cites work | TGF-beta signal transduction | Q22003891 |
| MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling | Q24310282 | ||
| Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes | Q24310852 | ||
| TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4 | Q24314661 | ||
| MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma | Q24315119 | ||
| Receptor-associated Mad homologues synergize as effectors of the TGF-beta response | Q24318330 | ||
| Fibroblast growth factor receptor 3 is a negative regulator of bone growth | Q24322706 | ||
| Mad-related genes in the human | Q24328786 | ||
| Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells | Q24656526 | ||
| A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells | Q24678065 | ||
| Measurement of leukocyte motility and chemotaxis parameters with a linear under-agarose migration assay | Q52703860 | ||
| Peripheral deletion of antigen-reactive T cells in oral tolerance. | Q54167741 | ||
| Risk factors for nosocomial infections caused by gram-negative bacilli. The Hellenic Antibiotic Resistance Study Group. | Q54581795 | ||
| Type I transforming growth factor-beta receptors on neutrophils mediate chemotaxis to transforming growth factor-beta | Q68251070 | ||
| Murine FGFR-1 is required for early postimplantation growth and axial organization | Q71989885 | ||
| Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice | Q72233696 | ||
| TGF-beta signalling from cell membrane to nucleus through SMAD proteins | Q28131770 | ||
| The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling | Q28243202 | ||
| Smad4 and FAST-1 in the assembly of activin-responsive factor | Q28248490 | ||
| Regulation of immune responses by TGF-beta | Q28271433 | ||
| Human Smad3 and Smad4 are sequence-specific transcription activators | Q28276193 | ||
| The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo | Q28512702 | ||
| Smad2 signaling in extraembryonic tissues determines anterior-posterior polarity of the early mouse embryo | Q28586864 | ||
| Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene | Q28593669 | ||
| Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling | Q28631440 | ||
| Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components | Q29036482 | ||
| Interleukin-10-deficient mice develop chronic enterocolitis | Q29547881 | ||
| Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene | Q29616540 | ||
| A transcriptional partner for MAD proteins in TGF-beta signalling | Q29622823 | ||
| Transforming growth factor type beta induces monocyte chemotaxis and growth factor production | Q34339289 | ||
| The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms | Q34349039 | ||
| Characterization of lymphocytes in the adult rat testis by flow cytometry: effects of activin and transforming growth factor beta on lymphocyte subsets in vitro | Q34464486 | ||
| The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice | Q36008239 | ||
| Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2. | Q36258971 | ||
| Transforming growth factor beta specifically enhances IgA production by lipopolysaccharide-stimulated murine B lymphocytes | Q36356779 | ||
| Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein | Q36573904 | ||
| Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering | Q36778446 | ||
| Defective neutrophil and monocyte motility in patients with early onset periodontitis | Q37040078 | ||
| Identification of Smad2, a human Mad-related protein in the transforming growth factor beta signaling pathway | Q38349140 | ||
| Smad2 role in mesoderm formation, left-right patterning and craniofacial development | Q41027581 | ||
| TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling | Q41083690 | ||
| 9,13-di-cis-Retinoic acid induces the production of tPA and activation of latent TGF-beta via RAR alpha in a human liver stellate cell line, LI90. | Q41099992 | ||
| Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways. | Q41157114 | ||
| A human Mad protein acting as a BMP-regulated transcriptional activator | Q41192122 | ||
| Antigen-specific TGF-beta1 secretion with bovine myelin oral tolerization in multiple sclerosis | Q41228728 | ||
| Reciprocal IFN-gamma and TGF-beta responses regulate the occurrence of mucosal inflammation | Q41370537 | ||
| Molecular factors associated with compartmentalization of gingival immune responses and transepithelial neutrophil migration | Q41402213 | ||
| The immunoregulatory effects of NK cells: the role of TGF-beta and implications for autoimmunity | Q41654453 | ||
| TGF-beta receptor signaling | Q41659039 | ||
| Neutrophil chemotaxis in response to TGF-beta isoforms (TGF-beta 1, TGF-beta 2, TGF-beta 3) is mediated by fibronectin | Q42498936 | ||
| The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors. | Q42638343 | ||
| Smad3 mutant mice develop metastatic colorectal cancer | Q45345236 | ||
| A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway | Q46482720 | ||
| Mad acts downstream of Dpp receptors, revealing a differential requirement for dpp signaling in initiation and propagation of morphogenesis in the Drosophila eye. | Q47070971 | ||
| Mothers against dpp encodes a conserved cytoplasmic protein required in DPP/TGF-beta responsive cells | Q47072372 | ||
| Factors involved in the differentiation of TGF-beta-producing cells from naive CD4+ T cells: IL-4 and IFN-gamma have opposing effects, while TGF-beta positively regulates its own production. | Q47937071 | ||
| Genomic structure of the human Smad3 gene and its infrequent alterations in colorectal cancers | Q48040403 | ||
| Activin A suppresses proliferation of interleukin-3-responsive granulocyte-macrophage colony-forming progenitors and stimulates proliferation and differentiation of interleukin-3-responsive erythroid burst-forming progenitors in the peripheral blood | Q51141712 | ||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | SMAD family member 3 | Q14903978 |
| P304 | page(s) | 1280–1291 | |
| P577 | publication date | 1999-03-01 | |
| P1433 | published in | The EMBO Journal | Q1278554 |
| P1476 | title | Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta | |
| P478 | volume | 18 |
| Q36990620 | 'Yin-Yang' functions of transforming growth factor-beta and T regulatory cells in immune regulation |
| Q38348424 | A Failure of Transforming Growth Factor-β1 Negative Regulation Maintains Sustained NF-κB Activation in Gut Inflammation |
| Q47988988 | A GEF activity-independent function for nuclear Net1 in Nodal signal transduction and mesendoderm formation |
| Q34625152 | A cytokine-mediated link between innate immunity, inflammation, and cancer |
| Q38680793 | A moderate response to plasmapheresis in nephrogenic systemic fibrosis |
| Q47824296 | A mutation update on the LDS associated genes TGFB2/3 and SMAD2/3. |
| Q37338950 | A negative feedback control of transforming growth factor-beta signaling by glycogen synthase kinase 3-mediated Smad3 linker phosphorylation at Ser-204. |
| Q34989137 | A novel approach for the generation of genetically modified mammary epithelial cell cultures yields new insights into TGFβ signaling in the mammary gland |
| Q53596084 | A pathway regulated by cell cycle inhibitor p27Kip1 and checkpoint inhibitor Smad3 is involved in the induction of T cell tolerance. |
| Q34306694 | AAV2/8-hSMAD3 gene delivery attenuates aortic atherogenesis, enhances Th2 response without fibrosis, in LDLR-KO mice on high cholesterol diet |
| Q47847040 | Aberrant Smad3 phosphoisoforms in cyst-lining epithelial cells in the cpk mouse, a model of autosomal recessive polycystic kidney disease |
| Q36007436 | Aberrant mucosal mast cell protease expression in the enteric epithelium of nematode-infected mice lacking the integrin alphavbeta6, a transforming growth factor-beta1 activator |
| Q46587212 | Abnormal mouse lung alveolarization caused by Smad3 deficiency is a developmental antecedent of centrilobular emphysema |
| Q36734862 | Absence of Smad3 induces neutrophil migration after cutaneous irradiation: possible contribution to subsequent radioprotection |
| Q42828663 | Acetylation of Smad2 by the co-activator p300 regulates activin and transforming growth factor beta response |
| Q91852975 | Activated CX3CL1/Smad2 Signals Prevent Neuronal Loss and Alzheimer's Tau Pathology-Mediated Cognitive Dysfunction |
| Q37342839 | Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes |
| Q34099993 | Activin regulates luteinizing hormone beta-subunit gene expression through Smad-binding and homeobox elements. |
| Q34436924 | Activin/Nodal signalling before implantation: setting the stage for embryo patterning |
| Q38872337 | Activins and Inhibins: Roles in Development, Physiology, and Disease |
| Q37109133 | Adenoviral gene transfer of bioactive TGFbeta1 to the rodent eye as a novel model for anterior subcapsular cataract |
| Q89976304 | Administration of Steamed and Freeze-Dried Mature Silkworm Larval Powder Prevents Hepatic Fibrosis and Hepatocellular Carcinogenesis by Blocking TGF-β/STAT3 Signaling Cascades in Rats |
| Q40563758 | Akt interacts directly with Smad3 to regulate the sensitivity to TGF-beta induced apoptosis |
| Q37971565 | Alterations in the Smad pathway in human cancers |
| Q55708893 | Altered expression of Smad proteins in T or NK-cell lymphomas. |
| Q80813887 | Altered gene expression in articular chondrocytes of Smad3(ex8/ex8) mice, revealed by gene profiling using microarrays |
| Q54981313 | Andrographolide Ameliorates Liver Fibrosis in Mice: Involvement of TLR4/NF-κB and TGF-β1/Smad2 Signaling Pathways. |
| Q37304321 | Angiogenesis-associated sequence variants relative to breast cancer recurrence and survival. |
| Q37410582 | Angiotensin II-dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis |
| Q28513597 | Antagonistic effects of Smad2 versus Smad7 are sensitive to their expression level during tooth development |
| Q82795328 | Apoptotic cells attenuate fulminant hepatitis by priming Kupffer cells to produce interleukin-10 through membrane-bound TGF-β |
| Q24298763 | Association of polymorphisms of IGF1R and genes in the transforming growth factor- beta /bone morphogenetic protein pathway with bacteremia in sickle cell anemia |
| Q28567679 | Autocrine loop between TGF-beta1 and IL-1beta through Smad3- and ERK-dependent pathways in rat pancreatic stellate cells |
| Q36241254 | Autocrine transforming growth factor-beta regulation of hematopoiesis: many outcomes that depend on the context |
| Q42555752 | Bacteria, inflammation, and colon cancer. |
| Q36788960 | Bacterial meningitis: the role of transforming growth factor-Beta in innate immunity and secondary brain damage |
| Q64093898 | Baishouwu Extract Suppresses the Development of Hepatocellular Carcinoma via TLR4/MyD88/NF-κB Pathway |
| Q26998388 | Balancing acts: the role of TGF-β in the mucosal immune system |
| Q36331266 | Biological responses to TGF-β in the mammary epithelium show a complex dependency on Smad3 gene dosage with important implications for tumor progression |
| Q42944220 | Blockade of transforming growth factor beta/Smad signaling in T cells by overexpression of Smad7 enhances antigen-induced airway inflammation and airway reactivity |
| Q28346591 | Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel disease |
| Q47131462 | C-reactive protein promotes acute kidney injury via Smad3-dependent inhibition of CDK2/cyclin E. |
| Q36370807 | CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness |
| Q34716304 | CD4+ CD25+ suppressor T cells: more questions than answers |
| Q40102596 | CEACAM5 and CEACAM6 are major target genes for Smad3-mediated TGF-beta signaling |
| Q42626979 | CTLA4Ig inhibits effector T cells through regulatory T cells and TGF-β. |
| Q37662148 | Carcinogen 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis is accelerated in Smad3 heterozygous mice compared to Smad3 wild type mice |
| Q34903220 | Celiac disease: from oral tolerance to intestinal inflammation, autoimmunity and lymphomagenesis. |
| Q37924871 | Cell biology of Smad2/3 linker region phosphorylation in vascular smooth muscle |
| Q35648713 | Cell surface fucosylation does not affect development of colon tumors in mice with germline Smad3 mutation |
| Q38259227 | Cellular and Molecular Mediators of Intestinal Fibrosis |
| Q34028060 | Cellular and molecular basis for the regulation of inflammation by TGF-beta |
| Q51026324 | Characterization of Smad3 knockout mouse derived skin cells. |
| Q30976369 | Characterization of the mouse Smad1 gene and its expression pattern in adult mouse tissues |
| Q33956709 | Cigarette smoke exposure aggravates air space enlargement and alveolar cell apoptosis in Smad3 knockout mice |
| Q50433101 | Clock1a affects mesoderm development and primitive hematopoiesis by regulating Nodal-Smad3 signaling in the zebrafish embryo. |
| Q33731106 | Combinatorial actions of Tgfβ and Activin ligands promote oligodendrocyte development and CNS myelination |
| Q37741923 | Connection between inflammation and carcinogenesis in gastrointestinal tract: focus on TGF-beta signaling |
| Q35025212 | Consequences of knocking out BMP signaling in the mouse |
| Q42702492 | Control of the development of CD8αα+ intestinal intraepithelial lymphocytes by TGF-β. |
| Q37277772 | Critical roles of the TGF-beta type I receptor ALK5 in perichondrial formation and function, cartilage integrity, and osteoblast differentiation during growth plate development |
| Q47229633 | Cyclin-dependent kinases regulate the antiproliferative function of Smads |
| Q53221636 | Cyclosporine A promotes cell proliferation, collagen and α-smooth muscle actin expressions in rat gingival fibroblasts by Smad3 activation and miR-29b suppression. |
| Q29616379 | Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer |
| Q46328407 | D-mannose induces regulatory T cells and suppresses immunopathology. |
| Q31060222 | Decreased levels of active SMAD2 correlate with poor prognosis in gastric cancer |
| Q54376104 | Defective IL10 signaling defining a subgroup of patients with inflammatory bowel disease. |
| Q91893506 | Delayed application of silver nanoparticles reveals the role of early inflammation in burn wound healing |
| Q42160419 | Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation |
| Q36231942 | Deletion of Smad3 improves cardiac allograft rejection in mice |
| Q36241231 | Deregulated TGF-beta signaling in leukemogenesis |
| Q38845667 | Development and characterization of IL-21-producing CD4+ T cells |
| Q44360250 | Developmental and stage-specific expression of Smad2 and Smad3 in rat testis |
| Q38568865 | Differential effects of Smad3 targeting in a murine model of chronic kidney disease |
| Q83158554 | Differential expression of SMAD3 transcripts is not regulated by cis-acting genetic elements but has a gender specificity |
| Q50114013 | Differential expression of microRNAs in peripheral blood mononuclear cells identifies autophagy and TGF-beta related signatures aberrantly expressed in inflammatory bowel disease. |
| Q24297637 | Differential regulation of TGF-beta signaling through Smad2, Smad3 and Smad4 |
| Q24671034 | Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer |
| Q47112591 | Distinct cytokine patterns may regulate the severity of neonatal asphyxia-an observational study. |
| Q37218781 | Early growth response 3 (Egr-3) is induced by transforming growth factor-β and regulates fibrogenic responses |
| Q36382816 | Effect of Regulatory T Cells on Promoting Apoptosis of T Lymphocyte and Its Regulatory Mechanism in Sepsis |
| Q43357710 | Effects of Sijunzi decoction and Yupingfeng powder on expression of janus kinase-signal transducer and activator of transcription signal pathway in the brain of spleen-deficiency model rats |
| Q36736835 | Emerging insights into Transforming growth factor beta Smad signal in hepatic fibrogenesis. |
| Q74601263 | Endless healing: TGF-beta, SMADs, and fibrosis |
| Q29620566 | Endothelial-to-mesenchymal transition contributes to cardiac fibrosis |
| Q39862975 | Enhanced expression of transcription factor GATA-4 in inflammatory bowel disease and its possible regulation by TGF-beta1. |
| Q42794343 | Enteric expression of the integrin alpha(v)beta(6) is essential for nematode-induced mucosal mast cell hyperplasia and expression of the granule chymase, mouse mast cell protease-1. |
| Q37065897 | Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation |
| Q34575283 | Essential role of Smad3 in angiotensin II-induced vascular fibrosis |
| Q34985015 | Estrogen modulates cutaneous wound healing by downregulating macrophage migration inhibitory factor |
| Q42428071 | Evaluation of Serum TNF-α and TGF-β in Patients with Oral Lichen Planus |
| Q36459569 | Evidence supporting a role for SMAD2/3 in bovine early embryonic development: potential implications for embryotropic actions of follistatin |
| Q89890492 | Expanding the spectrum of SMAD3-related phenotypes to agnathia-otocephaly |
| Q36951674 | Extracellular control of TGFbeta signalling in vascular development and disease |
| Q33643763 | Fate-determining mechanisms in epithelial-myofibroblast transition: major inhibitory role for Smad3 |
| Q54571621 | Fluorofenidone attenuates tubulointerstitial fibrosis by inhibiting TGF-β(1)-induced fibroblast activation. |
| Q30407691 | Follicle-stimulating hormone synthesis and fertility are intact in mice lacking SMAD3 DNA binding activity and SMAD2 in gonadotrope cells |
| Q74298040 | Functional consequences of tumorigenic missense mutations in the amino-terminal domain of Smad4 |
| Q33857584 | Functions of mammalian Smad genes as revealed by targeted gene disruption in mice |
| Q44278354 | Fusion proteins of retinoid receptors antagonize TGF-beta-induced growth inhibition of lung epithelial cells |
| Q37821995 | GI GEMs: genetically engineered mouse models of gastrointestinal disease |
| Q36793496 | GM-CSF contributes to aortic aneurysms resulting from SMAD3 deficiency. |
| Q36644279 | Gastric tumor development in Smad3-deficient mice initiates from forestomach/glandular transition zone along the lesser curvature |
| Q37340563 | Gene expression signatures in polyarticular juvenile idiopathic arthritis demonstrate disease heterogeneity and offer a molecular classification of disease subsets |
| Q52550786 | Genetic ablation of the tumor suppressor menin causes lethality at mid-gestation with defects in multiple organs. |
| Q33771627 | Genetic and Chemical Models of Colorectal Cancer in Mice |
| Q35577401 | Genetic and pathogenetic insights into inflammatory bowel disease |
| Q33824603 | Genetic approaches to TGFbeta signaling pathways |
| Q34393878 | Genetic- or transforming growth factor-beta 1-induced changes in epidermal peroxisome proliferator-activated receptor beta/delta expression dictate wound repair kinetics |
| Q37788639 | Genetics of childhood-onset inflammatory bowel disease |
| Q36629111 | Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases |
| Q24630117 | Getting 'Smad' about obesity and diabetes |
| Q35150251 | Global identification of SMAD2 target genes reveals a role for multiple co-regulatory factors in zebrafish early gastrulas. |
| Q34389954 | Global identification of Smad2 and Eomesodermin targets in zebrafish identifies a conserved transcriptional network in mesendoderm and a novel role for Eomesodermin in repression of ectodermal gene expression |
| Q42110086 | Growth differentiation factor 11 signaling controls retinoic acid activity for axial vertebral development |
| Q36586957 | Guarding the immune system: suppression of autoimmunity by CD4+CD25+ immunoregulatory T cells |
| Q37708392 | Guilt by rewiring: gene prioritization through network rewiring in genome wide association studies. |
| Q45345231 | Haploid loss of the tumor suppressor Smad4/Dpc4 initiates gastric polyposis and cancer in mice. |
| Q35859575 | Heavy Metal Ion Regulation of Gene Expression: MECHANISMS BY WHICH LEAD INHIBITS OSTEOBLASTIC BONE-FORMING ACTIVITY THROUGH MODULATION OF THE Wnt/β-CATENIN SIGNALING PATHWAY. |
| Q37723134 | Helicobacter infection is required for inflammation and colon cancer in SMAD3-deficient mice |
| Q33840844 | Hepatic deletion of Smad7 in mouse leads to spontaneous liver dysfunction and aggravates alcoholic liver injury |
| Q35372285 | Histone 3 lysine 9 (H3K9) methyltransferase recruitment to the interleukin-2 (IL-2) promoter is a mechanism of suppression of IL-2 transcription by the transforming growth factor-β-Smad pathway. |
| Q34062916 | Hypoxia inhibition of adipocytogenesis in human bone marrow stromal cells requires transforming growth factor-beta/Smad3 signaling |
| Q24642963 | IKKalpha, a critical regulator of epidermal differentiation and a suppressor of skin cancer |
| Q33857178 | IL1B induced Smad 7 negatively regulates gastrin expression |
| Q58549771 | Identification of SMAD3 as a Novel Mediator of Inflammation in Human Myometrium |
| Q55397601 | Immune cell expression of TGFβ1 in cancer with lymphoid stroma: dendritic cell and regulatory T cell contact. |
| Q35570447 | Immunomodulator FTY720 induces myofibroblast differentiation via the lysophospholipid receptor S1P3 and Smad3 signaling |
| Q39019244 | Immunoregulation by members of the TGFβ superfamily |
| Q24551154 | Inactivation of smad-transforming growth factor beta signaling by Ca(2+)-calmodulin-dependent protein kinase II |
| Q53408090 | Incisional wound healing in transforming growth factor-beta1 null mice. |
| Q42726353 | Increase of CD4(+)CD25(+) T cells in Smad3(-/-) mice |
| Q91671992 | Increased Smad3 and reduced Smad2 levels mediate the functional switch of TGF-β from growth suppressor to growth and metastasis promoter through TMEPAI/PMEPA1 in triple negative breast cancer |
| Q37469875 | Increased activation of latent TGF-β1 by αVβ3 in human Crohn's disease and fibrosis in TNBS colitis can be prevented by cilengitide |
| Q35872044 | Increased presence of effector lymphocytes during Helicobacter hepaticus-induced colitis |
| Q49580133 | Infection with enteric pathogens Salmonella typhimurium and Citrobacter rodentium modulate TGF-beta/Smad Signaling Pathways in the Intestine. |
| Q34737849 | Influenza promotes collagen deposition via αvβ6 integrin-mediated transforming growth factor β activation |
| Q46132181 | Inhibition of SMAD2 expression prevents murine palatal fusion |
| Q40417137 | Inhibition of the transforming growth factor beta (TGFbeta) pathway by interleukin-1beta is mediated through TGFbeta-activated kinase 1 phosphorylation of SMAD3. |
| Q43188545 | Inhibition of transforming growth factor-beta signalling attenuates interleukin (IL)-18 plus IL-2-induced interstitial lung disease in mice |
| Q35105653 | Inhibitory SMADs: potential regulators of ovarian function |
| Q37258903 | Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition |
| Q36416397 | Integrin beta6 mediates phospholipid and collectin homeostasis by activation of latent TGF-beta1. |
| Q37362030 | Integrin-mediated transforming growth factor-beta activation, a potential therapeutic target in fibrogenic disorders |
| Q40134089 | Intense pulsed light enhances transforming growth factor beta1/Smad3 signaling in acne-prone skin |
| Q35843231 | Interference with transforming growth factor-beta/ Smad3 signaling results in accelerated healing of wounds in previously irradiated skin |
| Q40468389 | Interleukin-6 regulation of transforming growth factor (TGF)-beta receptor compartmentalization and turnover enhances TGF-beta1 signaling. |
| Q34008698 | Invasive candidiasis stimulates hepatocyte and monocyte production of active transforming growth factor beta |
| Q38339058 | Involvement of Smad signaling in sphingosine 1-phosphate-mediated biological responses of keratinocytes |
| Q39790068 | Keratinocyte-specific Smad2 ablation results in increased epithelial-mesenchymal transition during skin cancer formation and progression |
| Q50459336 | Knocking out Smad3 favors allogeneic mouse fetal skin development in adult wounds. |
| Q34476955 | Lack of a role for transforming growth factor-beta in cytotoxic T lymphocyte antigen-4-mediated inhibition of T cell activation. |
| Q33609106 | Lens-specific expression of TGF-beta induces anterior subcapsular cataract formation in the absence of Smad3 |
| Q36756684 | Long Noncoding RNA Arid2-IR Is a Novel Therapeutic Target for Renal Inflammation |
| Q37371652 | Loss of NF-kappaB control and repression of Prdx6 gene transcription by reactive oxygen species-driven SMAD3-mediated transforming growth factor beta signaling |
| Q28591205 | Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia |
| Q28505578 | Loss of Smad3 gives rise to poor soft callus formation and accelerates early fracture healing |
| Q33857614 | Loss of Smad3 modulates wound healing |
| Q52085402 | Loss of cooperative function of transforming growth factor-beta signaling proteins, smad3 with embryonic liver fodrin, a beta-spectrin, in primary biliary cirrhosis. |
| Q53373344 | Loss of the Smad3 expression increases susceptibility to tumorigenicity in human gastric cancer. |
| Q53499188 | Macrophage-to-Myofibroblast Transition Contributes to Interstitial Fibrosis in Chronic Renal Allograft Injury. |
| Q51777596 | Maternal Smad3 deficiency compromises decidualization in mice. |
| Q35625107 | Mechanisms of Intestinal Serotonin Transporter (SERT) Upregulation by TGF-β1 Induced Non-Smad Pathways |
| Q34635877 | Mechanisms of TGF-beta signaling in regulation of cell growth and differentiation |
| Q28253085 | Mechanisms of action of TGF-beta in cancer: evidence for Smad3 as a repressor of the hTERT gene |
| Q33886458 | Mechanisms of intestinal inflammation and development of associated cancers: lessons learned from mouse models |
| Q33754181 | Mechanisms that mediate the development of fibrosis in patients with Crohn's disease |
| Q35006210 | Menin interacting proteins as clues toward the understanding of multiple endocrine neoplasia type 1. |
| Q64076321 | MiR-200a ameliorates peritoneal fibrosis and functional deterioration in a rat model of peritoneal dialysis |
| Q40773532 | Mice exclusively expressing the short isoform of Smad2 develop normally and are viable and fertile. |
| Q35788867 | Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation |
| Q28512142 | Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response |
| Q42563021 | Mice that lack activity of alphavbeta6- and alphavbeta8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice |
| Q53797400 | MicroRNA-29b inhibits peritoneal fibrosis in a mouse model of peritoneal dialysis. |
| Q52581027 | Microglia-derived TGF-beta as an important regulator of glioblastoma invasion--an inhibition of TGF-beta-dependent effects by shRNA against human TGF-beta type II receptor. |
| Q42778397 | Microglial-specific transcriptome changes following chronic alcohol consumption |
| Q28205777 | Molecular dimensions of gastrointestinal tumors: Some thoughts for digestion |
| Q53069060 | Mouse Sertoli cells sustain de novo generation of regulatory T cells by triggering the notch pathway through soluble JAGGED1. |
| Q34516144 | Mouse models of gastrointestinal tumors |
| Q38867429 | Mouse models of intestinal inflammation and cancer |
| Q33857591 | Murine models define the role of TGF-beta as a master regulator of immune cell function |
| Q44562492 | Mutation analysis of the Smad3 gene in human osteoarthritis. |
| Q36983409 | Negative regulators in homeostasis of naïve peripheral T cells. |
| Q43508070 | Nodal signaling uses activin and transforming growth factor-beta receptor-regulated Smads |
| Q37044600 | Noncanonical TGF-β signaling during mammary tumorigenesis |
| Q90010355 | Novel Interplay Between Smad1 and Smad3 Phosphorylation via AGE Regulates the Progression of Diabetic Nephropathy |
| Q47861814 | Novel mutations and expression alterations in SMAD3/TGFBR2 genes in oral carcinoma correlate with poor prognosis |
| Q36232250 | Obstructive nephropathy: insights from genetically engineered animals |
| Q39647327 | Overexpression of Smad7 results in severe pathological alterations in multiple epithelial tissues |
| Q24813066 | Overexpression of extracellular superoxide dismutase reduces acute radiation induced lung toxicity |
| Q24811751 | Paclitaxel modulates TGFbeta signaling in scleroderma skin grafts in immunodeficient mice. |
| Q34695847 | Pancreatic cancer cells respond to type I collagen by inducing snail expression to promote membrane type 1 matrix metalloproteinase-dependent collagen invasion |
| Q44659145 | Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival |
| Q35898494 | Phosphorylation status determines the opposing functions of Smad2/Smad3 as STAT3 cofactors in TH17 differentiation |
| Q40757292 | Physical and functional interaction between GATA-3 and Smad3 allows TGF-beta regulation of GATA target genes |
| Q33722118 | Pluripotent Nontumorigenic Adipose Tissue-Derived Muse Cells have Immunomodulatory Capacity Mediated by Transforming Growth Factor-β1. |
| Q45096816 | Prevention of fibrosis in experimental colitis by captopril: the role of tgf-beta1. |
| Q36747605 | Primary aldosteronism and impaired natriuresis in mice underexpressing TGFβ1. |
| Q40441867 | Prolonged anorexia and elevated plasma cytokine levels following myeloablative allogeneic hematopoietic cell transplant |
| Q35203175 | Protection from obesity and diabetes by blockade of TGF-β/Smad3 signaling |
| Q40358313 | RING finger-dependent ubiquitination by PRAJA is dependent on TGF-beta and potentially defines the functional status of the tumor suppressor ELF. |
| Q42073238 | Rapamycin inhibits transforming growth factor β-induced peritoneal angiogenesis by blocking the secondary hypoxic response |
| Q53262158 | Rat skin wound healing induced by alternagin-C, a disintegrin-like, Cys-rich protein from Bothrops alternatus venom. |
| Q45021930 | Receptor-regulated and inhibitory Smads are critical in regulating transforming growth factor beta-mediated Meckel's cartilage development |
| Q30540998 | Reciprocal regulation by TLR4 and TGF-β in tumor-initiating stem-like cells |
| Q46702165 | Reduced responsiveness of HLA-B27 transgenic rat cells to TGF-beta and IL-10-mediated regulation of IFN-gamma production |
| Q30439551 | Redundant roles of SMAD2 and SMAD3 in ovarian granulosa cells in vivo. |
| Q39134073 | Regulation of Hematopoiesis and Hematological Disease by TGF-β Family Signaling Molecules |
| Q34830660 | Regulation of cytokine signaling and inflammation |
| Q39097028 | Regulation of the Immune Response by TGF-β: From Conception to Autoimmunity and Infection |
| Q38948512 | Regulatory T Cells and Cancer: A Two-Sided Story |
| Q42264762 | Relative roles of TGF-beta1 and Wnt in the systemic regulation and aging of satellite cell responses |
| Q22011159 | Remarkable versatility of Smad proteins in the nucleus of transforming growth factor-beta activated cells |
| Q36049119 | Repressed TGF-β signaling through CagA-Smad3 interaction as pathogenic mechanisms of Helicobacter pylori-associated gastritis |
| Q36369531 | Requirement for transforming growth factor beta1 in controlling T cell apoptosis |
| Q41502015 | Requirement of TCF7L2 for TGF-beta-dependent transcriptional activation of the TMEPAI gene |
| Q43966747 | Resistance to exogenous TGF-β effects in patients with systemic lupus erythematosus |
| Q35426456 | Retinoic acid promotes myogenesis in myoblasts by antagonizing transforming growth factor-beta signaling via C/EBPβ |
| Q36698776 | Role of Smad3 in platelet-derived growth factor-C-induced liver fibrosis |
| Q28506745 | Role of Smad3 in the hormonal modulation of in vivo wound healing responses |
| Q55479087 | Role of Smad3 signaling in the epithelial‑mesenchymal transition of the lens epithelium following injury. |
| Q38060113 | Role of Smad7 in inflammatory bowel diseases |
| Q89509862 | Role of TGF- in Skin Chronic Wounds: A Keratinocyte Perspective |
| Q37044604 | Role of TGF-β and the tumor microenvironment during mammary tumorigenesis |
| Q28081170 | Role of TGFβ in regulation of the tumor microenvironment and drug delivery (review) |
| Q46465276 | Role of neuroinflammation and latent transcription factors in pathogenesis of Parkinson's disease. |
| Q37789682 | Role of transforming growth factor-β in inflammatory bowel disease and colitis-associated colon cancer. |
| Q36921552 | Roles of Smad3 in TGF-beta signaling during carcinogenesis |
| Q35090135 | Roles of TGFbeta signaling in epidermal/appendage development |
| Q37971998 | Roles of TGFβ signaling Smads in squamous cell carcinoma |
| Q109728604 | SARS‐CoV‐2 N Protein Induces Acute Kidney Injury via Smad3‐Dependent G1 Cell Cycle Arrest Mechanism |
| Q38076482 | SMAD regulatory networks construct a balanced immune system |
| Q47913844 | SMAD3 Regulates Follicle-stimulating Hormone Synthesis by Pituitary Gonadotrope Cells in Vivo |
| Q24605300 | SMAD3 deficiency promotes inflammatory aortic aneurysms in angiotensin II-infused mice via activation of iNOS |
| Q35617348 | SMAD3 deficiency promotes vessel wall remodeling, collagen fiber reorganization and leukocyte infiltration in an inflammatory abdominal aortic aneurysm mouse model. |
| Q35199407 | SMAD3 negatively regulates serum irisin and skeletal muscle FNDC5 and peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α) during exercise |
| Q36506934 | Scar wars: is TGFbeta the phantom menace in scleroderma? |
| Q34747455 | Scleroderma and Smads: dysfunctional Smad family dynamics culminating in fibrosis |
| Q42170401 | Self-antigen recognition by TGF beta1-deficient T cells causes their activation and systemic inflammation |
| Q36229334 | Semaphorin 7A plays a critical role in TGF-beta1-induced pulmonary fibrosis |
| Q36807051 | Sevoflurane protects against renal ischemia and reperfusion injury in mice via the transforming growth factor-beta1 pathway |
| Q37367853 | Signal transduction and Th17 cell differentiation |
| Q35238480 | Signal transduction pathways and transcriptional regulation in Th17 cell differentiation |
| Q36571580 | Signal transduction pathways and transcriptional regulation in the control of Th17 differentiation |
| Q33832063 | Signaling inputs converge on nuclear effectors in TGF-beta signaling |
| Q33969079 | Smad proteins and hepatocyte growth factor control parallel regulatory pathways that converge on beta1-integrin to promote normal liver development. |
| Q33674328 | Smad signaling in skeletal development and regeneration |
| Q34599300 | Smad signalling in the ovary |
| Q54649629 | Smad-dependent cooperative regulation of interleukin 2 receptor alpha chain gene expression by T cell receptor and transforming growth factor-beta. |
| Q28589411 | Smad2 and Smad3 coordinately regulate craniofacial and endodermal development |
| Q36610935 | Smad2 and Smad3 have differential sensitivity in relaying TGFβ signaling and inversely regulate early lineage specification |
| Q28267699 | Smad2 and Smad3 have opposing roles in breast cancer bone metastasis by differentially affecting tumor angiogenesis |
| Q28567374 | Smad2 and Smad3 play different roles in rat hepatic stellate cell function and alpha-smooth muscle actin organization |
| Q42507999 | Smad2 decelerates re-epithelialization during gingival wound healing |
| Q34455322 | Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis. |
| Q85887123 | Smad2 protects against TGF-β1/Smad3-mediated collagen synthesis in human hepatic stellate cells during hepatic fibrosis |
| Q36771343 | Smad2/Smad3 in endothelium is indispensable for vascular stability via S1PR1 and N-cadherin expressions |
| Q40729185 | Smad3 -signalling and Th2 cytokines in normal mouse airways and in a mouse model of asthma |
| Q47822539 | Smad3 and Bmal1 regulate p21 and S100A4 expression in myocardial stromal fibroblasts via TNF-α. |
| Q35779047 | Smad3 as a mediator of the fibrotic response |
| Q35103210 | Smad3 deficiency ameliorates experimental obliterative bronchiolitis in a heterotopic tracheal transplantation model |
| Q35058888 | Smad3 deficiency ameliorates hepatic fibrogenesis through the expression of senescence marker protein-30, an antioxidant-related protein |
| Q43882371 | Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice |
| Q24633409 | Smad3 deficiency in mice protects against insulin resistance and obesity induced by a high-fat diet |
| Q48307864 | Smad3 deficiency reduces neurogenesis in adult mice |
| Q40531865 | Smad3 is required for dedifferentiation of retinal pigment epithelium following retinal detachment in mice |
| Q44451036 | Smad3 is required for enamel biomineralization |
| Q42455590 | Smad3 is required for normal follicular follicle-stimulating hormone responsiveness in the mouse |
| Q34013157 | Smad3 knock-out mice as a useful model to study intestinal fibrogenesis |
| Q37677420 | Smad3 knockout mice exhibit impaired intestinal mucosal healing |
| Q52620425 | Smad3 mediates ANG II-induced hypertensive kidney disease in mice. |
| Q44317639 | Smad3 mediates the TGF-beta-induced contraction of type I collagen gels by mouse embryo fibroblasts |
| Q51507079 | Smad3 plays an inhibitory role in phosphate-induced vascular smooth muscle cell calcification. |
| Q42317402 | Smad3 promotes cancer progression by inhibiting E4BP4-mediated NK cell development |
| Q39758487 | Smad3 protein levels are modulated by Ras activity and during the cell cycle to dictate transforming growth factor-beta responses |
| Q37257648 | Smad3 reduces susceptibility to hepatocarcinoma by sensitizing hepatocytes to apoptosis through downregulation of Bcl-2. |
| Q33756827 | Smad3 signaling in the regenerating liver: implications for the regulation of IL-6 expression |
| Q35083441 | Smad3 signaling is required for epithelial-mesenchymal transition of lens epithelium after injury |
| Q24615313 | Smad3 signaling is required for satellite cell function and myogenic differentiation of myoblasts |
| Q43231611 | Smad3-dependent and -independent pathways are involved in peritoneal membrane injury |
| Q35672543 | Smad3-dependent signaling underlies the TGF-β1-mediated enhancement in astrocytic iNOS expression |
| Q38388639 | Smad3-mediated upregulation of miR-21 promotes renal fibrosis |
| Q80383784 | Smad4 is required for the normal organization of the cartilage growth plate |
| Q24309082 | Smad7 is required for the development and function of the heart |
| Q26865998 | Smads as therapeutic targets for chronic kidney disease |
| Q47914100 | Supplementation with galacto-oligosaccharides increases the percentage of NK cells and reduces colitis severity in Smad3-deficient mice |
| Q50737572 | Suppression of malignancy by Smad3 in mouse embryonic stem cell formed teratoma. |
| Q40566610 | Suppression of matrix metalloproteinase-9 transcription by transforming growth factor-beta is mediated by a nuclear factor-kappaB site |
| Q34414642 | Suppressor and oncogenic roles of transforming growth factor-beta and its signaling pathways in tumorigenesis |
| Q33772861 | Synergy of Transforming Growth Factor Beta 1 and All Trans Retinoic Acid in the Treatment of Inflammatory Bowel Disease: Role of Regulatory T cells |
| Q38339429 | Systems biology of ovine intestinal parasite resistance: disease gene modules and biomarkers |
| Q53073013 | T Cell Receptor-Regulated TGF-β Type I Receptor Expression Determines T Cell Quiescence and Activation. |
| Q36369541 | T cell death and transforming growth factor beta1 |
| Q28594881 | TGF beta 1 inhibits Ca2+-calcineurin-mediated activation in thymocytes |
| Q36946967 | TGF beta-mediated BIM expression and apoptosis are regulated through SMAD3-dependent expression of the MAPK phosphatase MKP2 |
| Q36259774 | TGF-beta 1 inhibition of IFN-gamma-induced signaling and Th1 gene expression in CD4+ T cells is Smad3 independent but MAP kinase dependent |
| Q33722462 | TGF-beta and regulatory T cell in immunity and autoimmunity |
| Q36187040 | TGF-beta inhibitors for the treatment of cancer |
| Q40445843 | TGF-beta inhibits p70 S6 kinase via protein phosphatase 2A to induce G(1) arrest |
| Q74070676 | TGF-beta released by apoptotic T cells contributes to an immunosuppressive milieu |
| Q35969335 | TGF-beta signal transduction in oro-facial health and non-malignant disease (part I). |
| Q36871584 | TGF-beta signaling alterations and susceptibility to colorectal cancer |
| Q28139850 | TGF-beta signaling by Smad proteins |
| Q34316170 | TGF-beta signaling in mammary gland development and tumorigenesis. |
| Q29615427 | TGF-beta signaling in tumor suppression and cancer progression |
| Q35628232 | TGF-beta, T-cell tolerance and anti-CD3 therapy |
| Q39947013 | TGF-beta/Smad signaling defects in inflammatory bowel disease: mechanisms and possible novel therapies for chronic inflammation |
| Q36342408 | TGF-beta/Smad3 signals repress chondrocyte hypertrophic differentiation and are required for maintaining articular cartilage |
| Q37349788 | TGF-beta1 and Smad7 in the regulation of IBD. |
| Q24813710 | TGF-beta1 and serum both stimulate contraction but differentially affect apoptosis in 3D collagen gels. |
| Q28568787 | TGF-beta1 blockade of microglial chemotaxis toward Abeta aggregates involves SMAD signaling and down-regulation of CCL5 |
| Q54641474 | TGF-beta1 production by CD4+ CD25+ regulatory T cells is not essential for suppression of intestinal inflammation. |
| Q33559621 | TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer |
| Q28511171 | TGF-beta3-dependent SMAD2 phosphorylation and inhibition of MEE proliferation during palatal fusion |
| Q35668744 | TGF-beta: the perpetrator of immune suppression by regulatory T cells and suicidal T cells |
| Q39155183 | TGF-β Family Signaling in Connective Tissue and Skeletal Diseases |
| Q37777380 | TGF-β Function in Immune Suppression |
| Q48611625 | TGF-β Mediates Renal Fibrosis via the Smad3-Erbb4-IR Long Noncoding RNA Axis. |
| Q55515390 | TGF-β in T Cell Biology: Implications for Cancer Immunotherapy. |
| Q39324100 | TGF-β in inflammatory bowel disease: a key regulator of immune cells, epithelium, and the intestinal microbiota |
| Q29036999 | TGF-β signaling in T cells: roles in lymphoid and epithelial neoplasia |
| Q35014257 | TGF-β signalling is required for CD4⁺ T cell homeostasis but dispensable for regulatory T cell function |
| Q36387273 | TGF-β-SMAD3 signaling mediates hepatic bile acid and phospholipid metabolism following lithocholic acid-induced liver injury |
| Q35142712 | TGF-β/Smad3 signaling promotes renal fibrosis by inhibiting miR-29 |
| Q44411475 | TGF-β1 Regulates Lymphocyte Homeostasis by Preventing Activation and Subsequent Apoptosis of Peripheral Lymphocytes |
| Q48364918 | TGF-β1/Smad3 Pathway Targets PP2A-AMPK-FoxO1 Signaling to Regulate Hepatic Gluconeogenesis |
| Q47132510 | TGF-β1/Smad3 Signaling Pathway Mediates T-2 Toxin-Induced Decrease of Type II Collagen in Cultured Rat Chondrocytes |
| Q28067425 | TGF-β1/Smads and miR-21 in Renal Fibrosis and Inflammation |
| Q57289200 | TGF-β2 downregulates osteogenesis under inflammatory conditions in dental follicle stem cells |
| Q36239510 | TGF-β3 Inhibits Antibody Production by Human B Cells. |
| Q36337915 | TGFbeta pathobiology in the eye. |
| Q36989149 | TGFbeta1 and Treg cells: alliance for tolerance |
| Q28083107 | TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and Metastasis |
| Q37976673 | TGFβ signaling and cardiovascular diseases |
| Q38200065 | TGFβ signaling in cartilage development and maintenance |
| Q36098652 | TGFβ/Smad3 signal pathway is not required for epidermal Langerhans cell development |
| Q44590698 | TGF‐β down‐regulates IL‐6 signaling in intestinal epithelial cells: Critical role of SMAD‐2 |
| Q38271793 | TLR4-dependent tumor-initiating stem cell-like cells (TICs) in alcohol-associated hepatocellular carcinogenesis |
| Q35102837 | Targeted disruption of TGF-beta/Smad3 signaling modulates skin fibrosis in a mouse model of scleroderma |
| Q36991087 | Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction |
| Q37367704 | TbetaRI independently activates Smad- and CD2AP-dependent pathways in podocytes |
| Q36083442 | Tgf-beta superfamily and mouse craniofacial development: interplay of morphogenetic proteins and receptor signaling controls normal formation of the face. |
| Q28239297 | Tgf-beta3-induced palatal fusion is mediated by Alk-5/Smad pathway |
| Q50566729 | The DNA-binding inhibitor Id3 regulates IL-9 production in CD4(+) T cells. |
| Q24805956 | The Smads |
| Q33857580 | The Smads: transcriptional regulation and mouse models |
| Q37261631 | The TGF-beta paradox in human cancer: an update |
| Q38963328 | The TGF-β Family in the Reproductive Tract |
| Q38558364 | The TGF-β/Smad System in IBD Pathogenesis |
| Q42477100 | The effects of TGF-β1 on the expression of type IV collagenases in mouse peritoneal macrophages |
| Q34049736 | The endogenous ratio of Smad2 and Smad3 influences the cytostatic function of Smad3. |
| Q38365115 | The immune suppressive function of transforming growth factor-β (TGF-β) in human diseases |
| Q37212182 | The immune-stimulating peptide WKYMVm has therapeutic effects against ulcerative colitis |
| Q35896486 | The mechanism of TGF-β signaling during palate development |
| Q39123810 | The microRNA miR-433 promotes renal fibrosis by amplifying the TGF-β/Smad3-Azin1 pathway |
| Q34708215 | The regulation of IgA class switching. |
| Q28508789 | The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling |
| Q36563513 | The roles for cytokines in the generation and maintenance of regulatory T cells |
| Q44888250 | The roles of Smad2 and Smad3 in the development of chemically induced skin tumors in mice |
| Q36370178 | The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease |
| Q34307626 | The transcriptional role of Smads and FAST (FoxH1) in TGFbeta and activin signalling |
| Q36371664 | Therapeutic strategies against TGF-beta signaling pathway in hepatic fibrosis |
| Q35006253 | Thioredoxin1 downregulates oxidized low-density lipoprotein-induced adhesion molecule expression via Smad3 protein |
| Q28203889 | Tob is a negative regulator of activation that is expressed in anergic and quiescent T cells |
| Q34146020 | Transcription factor FoxO1 is essential for enamel biomineralization |
| Q37760477 | Transcriptional regulation of T helper 17 cell differentiation |
| Q38354527 | Transcriptional regulation of tristetraprolin by transforming growth factor-beta in human T cells |
| Q43134768 | Transforming Growth Factor Beta Signaling in Cutaneous Wound Healing: Lessons Learned from Animal Studies |
| Q38988997 | Transforming Growth Factor β Superfamily Signaling in Development of Colorectal Cancer |
| Q38983015 | Transforming Growth Factor-β (TGF-β) Directly Activates the JAK1-STAT3 Axis to Induce Hepatic Fibrosis in Coordination with the SMAD Pathway. |
| Q33724405 | Transforming growth factor beta facilitates beta-TrCP-mediated degradation of Cdc25A in a Smad3-dependent manner |
| Q40265633 | Transforming growth factor beta suppresses human telomerase reverse transcriptase (hTERT) by Smad3 interactions with c-Myc and the hTERT gene |
| Q34352056 | Transforming growth factor beta, pleiotropic regulator of hematopoietic stem cells: potential physiological and clinical relevance |
| Q54979452 | Transforming growth factor β2 (TGFβ2) signaling plays a key role in glucocorticoid-induced ocular hypertension. |
| Q39316961 | Transforming growth factor β: a master regulator of the gut microbiota and immune cell interactions. |
| Q40658888 | Transforming growth factor-beta 1 inhibits non-pathogenic Gram negative bacteria-induced NF-kappa B recruitment to the interleukin-6 gene promoter in intestinal epithelial cells through modulation of histone acetylation |
| Q24793229 | Transforming growth factor-beta and breast cancer: Lessons learned from genetically altered mouse models |
| Q37089424 | Transforming growth factor-beta and the glomerular filtration barrier |
| Q35748961 | Transforming growth factor-beta mediates intestinal healing and susceptibility to injury in vitro and in vivo through epithelial cells |
| Q53507300 | Transforming growth factor-beta regulates house dust mite-induced allergic airway inflammation but not airway remodeling. |
| Q34438032 | Transforming growth factor-beta signal transduction in epithelial cells. |
| Q37098304 | Transforming growth factor-beta signaling and ubiquitinators in cancer. |
| Q36649628 | Transforming growth factor-beta-regulated miR-24 promotes skeletal muscle differentiation |
| Q37169507 | Transforming growth factor-beta/Smad3 signaling regulates insulin gene transcription and pancreatic islet beta-cell function |
| Q34401282 | Transforming growth factor-beta/Smad3 signalling regulates inflammatory responses in a murine model of contact hypersensitivity |
| Q24600173 | Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism |
| Q44904226 | Transforming growth factor-beta1 signaling contributes to development of smooth muscle cells from embryonic stem cells. |
| Q34789300 | Transforming growth factor-β and the hallmarks of cancer |
| Q37916975 | Transforming growth factor-β in the gastrointestinal and hepatic tumor microenvironment. |
| Q54194408 | Transforming growth factor-β1 mediates psoriasis-like lesions via a Smad3-dependent mechanism in mice. |
| Q35572314 | Transforming growth factor-β1 regulated phosphorylated AKT and interferon gamma expressions are associated with epithelial cell survival in rhesus macaque colon explants. |
| Q38712991 | Transforming growth factor-β1 regulates the nascent hematopoietic stem cell niche by promoting gluconeogenesis |
| Q35093790 | Transforming growth factor-β1 suppression of endotoxin-induced heme oxygenase-1 in macrophages involves activation of Smad2 and downregulation of Ets-2. |
| Q37272232 | Transforming growth factor-β3 (TGF-β3) knock-in ameliorates inflammation due to TGF-β1 deficiency while promoting glucose tolerance. |
| Q34534465 | Tumour necrosis factor in mouse models of chronic intestinal inflammation |
| Q24683744 | Twisted gastrulation (Tsg) is regulated by Tob and enhances TGF-beta signaling in activated T lymphocytes |
| Q35026971 | Two major Smad pathways in TGF-beta superfamily signalling. |
| Q35774267 | Two sides of the story? Smad4 loss in pancreatic cancer versus head-and-neck cancer |
| Q44979237 | Unique and redundant roles of Smad3 in TGF-beta-mediated regulation of long bone development in organ culture |
| Q64235119 | Uterine double-conditional inactivation of and in mice causes endometrial dysregulation, infertility, and uterine cancer |
| Q37574065 | Uterus hyperplasia and increased carcinogen-induced tumorigenesis in mice carrying a targeted mutation of the Chk2 phosphorylation site in Brca1 |
| Q34399941 | Vasohibin-1 deficiency enhances renal fibrosis and inflammation after unilateral ureteral obstruction |
| Q37125281 | Vitamin D Deficiency Promotes Liver Tumor Growth in Transforming Growth Factor-β/Smad3-Deficient Mice Through Wnt and Toll-like Receptor 7 Pathway Modulation. |
| Q57470839 | WNT signaling memory is required for ACTIVIN to function as a morphogen in human gastruloids |
| Q90266281 | Wnt, Notch, and TGF-β Pathways Impinge on Hedgehog Signaling Complexity: An Open Window on Cancer |
| Q37998914 | Working out mechanisms of controlled/physiologic inflammation in the GI tract |
| Q73177859 | Wounding Smad |
| Q52117451 | Zebrafish Smad7 is regulated by Smad3 and BMP signals. |
| Q42590746 | hCLP46 increases Smad3 protein stability via inhibiting its ubiquitin-proteasomal degradation |
| Q34124178 | miR-192 mediates TGF-beta/Smad3-driven renal fibrosis |
| Q36014083 | miR-29 inhibits bleomycin-induced pulmonary fibrosis in mice. |
| Q46891841 | smad2 and smad3 are required for mesendoderm induction by transforming growth factor-beta/nodal signals in zebrafish |
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