| scholarly article | Q13442814 |
| P356 | DOI | 10.1152/AJPRENAL.00595.2011 |
| P698 | PubMed publication ID | 22237801 |
| P2093 | author name string | Zhen Liu | |
| Hui Y Lan | |||
| Xiao R Huang | |||
| P2860 | cites work | Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation | Q24290777 |
| Mechanisms of TGF-beta signaling from cell membrane to the nucleus | Q27860785 | ||
| Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes | Q28188162 | ||
| Angiotensin II induces connective tissue growth factor and collagen I expression via transforming growth factor-beta-dependent and -independent Smad pathways: the role of Smad3 | Q28569602 | ||
| Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta | Q28594801 | ||
| Ultrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney. | Q30499402 | ||
| Advanced glycation end-products induce tubular CTGF via TGF-beta-independent Smad3 signaling | Q33711306 | ||
| Angiotensin II-induced hypertrophy of cultured murine proximal tubular cells is mediated by endogenous transforming growth factor-beta | Q33902166 | ||
| Hypertensive nephropathy: prevention and treatment recommendations | Q34131899 | ||
| Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis. | Q34455322 | ||
| Down-regulation of Smad7 expression by ubiquitin-dependent degradation contributes to renal fibrosis in obstructive nephropathy in mice | Q34514594 | ||
| The protective role of Smad7 in diabetic kidney disease: mechanism and therapeutic potential | Q34527184 | ||
| Essential role of Smad3 in angiotensin II-induced vascular fibrosis | Q34575283 | ||
| Angiotensin II: a key factor in the inflammatory and fibrotic response in kidney diseases | Q36310340 | ||
| Renal injury due to renin-angiotensin-aldosterone system activation of the transforming growth factor-beta pathway | Q36598311 | ||
| Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction | Q36991087 | ||
| Smad7 as a therapeutic agent for chronic kidney diseases. | Q37175439 | ||
| Smad ubiquitination regulatory factor-2 in the fibrotic kidney: regulation, target specificity, and functional implication | Q37244477 | ||
| NF-kappaB in renal inflammation | Q37774798 | ||
| Angiotensin II as a morphogenic cytokine stimulating renal fibrogenesis | Q37896399 | ||
| Diverse roles of TGF-β/Smads in renal fibrosis and inflammation | Q37934555 | ||
| Signaling mechanism of TGF-beta1 in prevention of renal inflammation: role of Smad7. | Q40443101 | ||
| Angiotensin II stimulates expression of transforming growth factor beta receptor type II in cultured mouse proximal tubular cells | Q40927675 | ||
| Interactions of transforming growth factor-beta and angiotensin II in renal fibrosis | Q41695601 | ||
| Effect of losartan on TGF-beta1 and urinary albumin excretion in patients with type 2 diabetes mellitus and microalbuminuria | Q43615549 | ||
| Antihypertensive effects of chronic anti-TGF-beta antibody therapy in Dahl S rats | Q44107276 | ||
| Add-on anti-TGF-beta antibody to ACE inhibitor arrests progressive diabetic nephropathy in the rat. | Q44486199 | ||
| Interactions between angiotensin II and NF-kappaB-dependent pathways in modulating macrophage infiltration in experimental diabetic nephropathy. | Q45000528 | ||
| Transforming growth factor beta1 and additional renoprotective effect of combination ACE inhibitor and angiotensin II receptor blocker in hypertensive subjects with minor renal abnormalities: a 24-week randomized controlled trial. | Q45270277 | ||
| Blockade of NFkappaB activation and renal inflammation by ultrasound-mediated gene transfer of Smad7 in rat remnant kidney. | Q45308027 | ||
| Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model | Q45862411 | ||
| Smad7 gene therapy ameliorates an autoimmune crescentic glomerulonephritis in mice. | Q45867788 | ||
| Angiotensin II activates the Smad pathway in vascular smooth muscle cells by a transforming growth factor-beta-independent mechanism | Q46481430 | ||
| Neutralization of transforming growth factor-beta attenuates hypertension and prevents renal injury in uremic rats | Q46691716 | ||
| Effect of low-dose dual blockade of renin-angiotensin system on urinary TGF-beta in type 2 diabetic patients with advanced kidney disease | Q46837580 | ||
| Disruption of the Smad7 gene promotes renal fibrosis and inflammation in unilateral ureteral obstruction (UUO) in mice. | Q52590979 | ||
| P433 | issue | 8 | |
| P921 | main subject | kidney disease | Q1054718 |
| P304 | page(s) | F986-97 | |
| P577 | publication date | 2012-01-11 | |
| P1433 | published in | American Journal of Physiology - Renal Physiology | Q2610177 |
| P1476 | title | Smad3 mediates ANG II-induced hypertensive kidney disease in mice. | |
| P478 | volume | 302 |
| Q37419118 | Activation of FXR protects against renal fibrosis via suppressing Smad3 expression |
| Q35838004 | Angiotensin-(1-7) Attenuates Kidney Injury Due to Obstructive Nephropathy in Rats |
| Q51169038 | Association study of common variations of FBN1 gene and essential hypertension in Han Chinese population |
| Q60222307 | Captopril mitigates splenomegaly and myelofibrosis in the Gata1 murine model of myelofibrosis |
| Q36142616 | Cofilin1 is involved in hypertension-induced renal damage via the regulation of NF-κB in renal tubular epithelial cells |
| Q37093818 | Comprehensive genomic profiling in diabetic nephropathy reveals the predominance of proinflammatory pathways |
| Q34875675 | Deficiency of Smad7 enhances cardiac remodeling induced by angiotensin II infusion in a mouse model of hypertension |
| Q38959449 | Deficiency of the Angiotensinase Aminopeptidase A Increases Susceptibility to Glomerular Injury |
| Q34542559 | Disruption of Smad7 promotes ANG II-mediated renal inflammation and fibrosis via Sp1-TGF-β/Smad3-NF.κB-dependent mechanisms in mice. |
| Q91650519 | Diverse Role of TGF-β in Kidney Disease |
| Q99708624 | Dual deficiency of angiotensin-converting enzyme-2 and Mas receptor enhances angiotensin II-induced hypertension and hypertensive nephropathy |
| Q36575572 | Elevated Endothelial Hypoxia-Inducible Factor-1α Contributes to Glomerular Injury and Promotes Hypertensive Chronic Kidney Disease |
| Q35082779 | Endothelial dysfunction exacerbates renal interstitial fibrosis through enhancing fibroblast Smad3 linker phosphorylation in the mouse obstructed kidney. |
| Q92308460 | Ginsenoside Rg3 Attenuates Angiotensin II-Mediated Renal Injury in Rats and Mice by Upregulating Angiotensin-Converting Enzyme 2 in the Renal Tissue |
| Q92618428 | Indoxyl Sulfate Induces Renal Fibroblast Activation through a Targetable Heat Shock Protein 90-Dependent Pathway |
| Q60938842 | JYYS Granule Mitigates Renal Injury in Clinic and in Spontaneously Hypertensive Rats by Inhibiting NF-B Signaling-Mediated Microinflammation |
| Q52668596 | Kidney disease models: tools to identify mechanisms and potential therapeutic targets. |
| Q36756684 | Long Noncoding RNA Arid2-IR Is a Novel Therapeutic Target for Renal Inflammation |
| Q53499188 | Macrophage-to-Myofibroblast Transition Contributes to Interstitial Fibrosis in Chronic Renal Allograft Injury. |
| Q38861678 | Metformin Prevents Renal Fibrosis in Mice with Unilateral Ureteral Obstruction and Inhibits Ang II-Induced ECM Production in Renal Fibroblasts. |
| Q38062404 | Molecular targets for treatment of kidney fibrosis |
| Q92310282 | PROTACs: great opportunities for academia and industry |
| Q61814799 | Regulation of TGF-β1 on PI3KC3 and its role in hypertension-induced vascular injuries |
| Q38020840 | Regulation of the transforming growth factor β pathway by reversible ubiquitylation |
| Q64275933 | Renoprotective Effect of the Histone Deacetylase Inhibitor CG200745 in DOCA-Salt Hypertensive Rats |
| Q36796579 | Renoprotective effect of combined inhibition of angiotensin-converting enzyme and histone deacetylase |
| Q54282708 | Renoprotective effects of sildenafil in DOCA-salt hypertensive rats. |
| Q41857602 | Resveratrol ameliorates renal injury in spontaneously hypertensive rats by inhibiting renal micro-inflammation |
| Q38598542 | Role of Smad signaling in kidney disease |
| Q28278757 | Role of the TGF-β/BMP-7/Smad pathways in renal diseases |
| Q51039701 | SREBP-1 is a novel mediator of TGFβ1 signaling in mesangial cells |
| Q38888431 | ShenKang injection suppresses kidney fibrosis and oxidative stress via transforming growth factor-β/Smad3 signalling pathway in vivo and in vitro. |
| Q47822539 | Smad3 and Bmal1 regulate p21 and S100A4 expression in myocardial stromal fibroblasts via TNF-α. |
| Q35058888 | Smad3 deficiency ameliorates hepatic fibrogenesis through the expression of senescence marker protein-30, an antioxidant-related protein |
| Q50588263 | Smad3 deficiency protects mice from obesity-induced podocyte injury that precedes insulin resistance. |
| Q35828473 | Smad7 protects against chronic aristolochic acid nephropathy in mice |
| Q55242511 | Specific Inhibitor of Smad3 (SIS3) Attenuates Fibrosis, Apoptosis, and Inflammation in Unilateral Ureteral Obstruction Kidneys by Inhibition of Transforming Growth Factor β (TGF-β)/Smad3 Signaling. |
| Q48611625 | TGF-β Mediates Renal Fibrosis via the Smad3-Erbb4-IR Long Noncoding RNA Axis. |
| Q26851198 | TGF-β/Smad signaling in renal fibrosis |
| Q28067425 | TGF-β1/Smads and miR-21 in Renal Fibrosis and Inflammation |
| Q47313741 | The methyltransferase SET9 regulates TGFB1 activation of renal fibroblasts via interaction with SMAD3. |
| Q99584180 | Treatment of Hypertensive Heart Disease by Targeting Smad3 Signaling in Mice |
| Q36545653 | Treatment of renal fibrosis by rebalancing TGF-β/Smad signaling with the combination of asiatic acid and naringenin. |
| Q39413020 | miR-29b as a therapeutic agent for angiotensin II-induced cardiac fibrosis by targeting TGF-β/Smad3 signaling |
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