Prostaglandin E2 suppresses antifungal immunity by inhibiting interferon regulatory factor 4 function and interleukin-17 expression in T cells.

scientific article published on 29 March 2012

Prostaglandin E2 suppresses antifungal immunity by inhibiting interferon regulatory factor 4 function and interleukin-17 expression in T cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.IMMUNI.2012.02.013
P932PMC publication ID3334441
P698PubMed publication ID22464170
P5875ResearchGate publication ID223992751

P50authorSandip K DattaQ57017895
P2093author name stringArthur L Shaffer
Peter R Williamson
Patricia A Valdez
Brian M Janelsins
Paul J Vithayathil
P2860cites workSelective regulatory function of Socs3 in the formation of IL-17-secreting T cellsQ24547568
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Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signalingQ41330743
Cryptococcus neoformans produces authentic prostaglandin E2 without a cyclooxygenaseQ41908929
Characterization of prostaglandin E2 production by Candida albicansQ42432379
The Candida Th17 response is dependent on mannan- and beta-glucan-induced prostaglandin E2.Q42830119
Endogenous PGE2 promotes the induction of human Th17 responses by fungal ß-glucan.Q42921088
Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokinesQ43627196
Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cellsQ43991749
Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells.Q44453951
Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells.Q45939390
Prostaglandin E2 enhances Th17 responses via modulation of IL-17 and IFN-gamma production by memory CD4+ T cellsQ46041262
Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in T(H)17 cells.Q46052625
IL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with Cryptococcus neoformansQ46970232
Analysis of the defects responsible for the impaired regulation of EBV-induced B cell proliferation by rheumatoid arthritis lymphocytes. II. Role of monocytes and the increased sensitivity of rheumatoid arthritis lymphocytes to prostaglandin EQ53558612
A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma.Q55044497
The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4Q80737734
IL-23 enhances the inflammatory cell response in Cryptococcus neoformans infection and induces a cytokine pattern distinct from IL-12Q82176433
Administration of IL-23 engages innate and adaptive immune mechanisms during fungal infectionQ84968375
Lineage-specific modulation of interleukin 4 signaling by interferon regulatory factor 4Q24671741
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cellsQ27860620
STAT3 mutations in the hyper-IgE syndromeQ28249785
Bcl6 mediates the development of T follicular helper cellsQ28252825
Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptorQ28273769
STAT3 regulates cytokine-mediated generation of inflammatory helper T cellsQ28286840
T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gammaQ28506783
Prostaglandin E2-EP4 signaling promotes immune inflammation through Th1 cell differentiation and Th17 cell expansionQ28509130
Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndromeQ29614595
Essential autocrine regulation by IL-21 in the generation of inflammatory T cellsQ29616147
Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDSQ29617372
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxinsQ29620097
Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokinesQ33348588
Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type IQ33656182
Transcriptional network of multiple capsule and melanin genes governed by the Cryptococcus neoformans cyclic AMP cascadeQ33719196
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control T(H)2 responsesQ33830564
Mucosal adjuvant activity of cholera toxin requires Th17 cells and protects against inhalation anthraxQ33935005
Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunityQ34025875
Dysregulated T helper cell differentiation in the absence of interferon regulatory factor 4.Q34154407
Interleukin-17 is not required for classical macrophage activation in a pulmonary mouse model of Cryptococcus neoformans infection.Q34309693
RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cellsQ34441341
The role of IRF-4 in transcriptional regulationQ34532748
Prostaglandins as modulators of immunityQ34543566
IL-23 and IL-17A, but not IL-12 and IL-22, are required for optimal skin host defense against Candida albicansQ34789143
Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis.Q35141261
Analysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 transcription factorsQ35736556
Anti-cytokine autoantibodies are associated with opportunistic infection in patients with thymic neoplasiaQ35876586
Role of laccase in the biology and virulence of Cryptococcus neoformansQ35894021
Interleukin-23 (IL-23)-IL-17 cytokine axis in murine Pneumocystis carinii infectionQ35913387
Effect of the laccase gene CNLAC1, on virulence of Cryptococcus neoformansQ36367081
Prostaglandin E2 synergistically with interleukin-23 favors human Th17 expansionQ36948594
Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasisQ37106755
Critical regulation of early Th17 cell differentiation by interleukin-1 signalingQ37250727
Robust Th1 and Th17 immunity supports pulmonary clearance but cannot prevent systemic dissemination of highly virulent Cryptococcus neoformans H99Q37462710
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectprostaglandin E2Q416554
P304page(s)668-679
P577publication date2012-03-29
P1433published inImmunityQ6005457
P1476titleProstaglandin E2 suppresses antifungal immunity by inhibiting interferon regulatory factor 4 function and interleukin-17 expression in T cells
P478volume36

Reverse relations

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