Inhibition of protein translation as a novel mechanism for prostaglandin E2 regulation of cell functions

scientific article published on 26 September 2013

Inhibition of protein translation as a novel mechanism for prostaglandin E2 regulation of cell functions is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1096/FJ.13-231720
P932PMC publication ID3868831
P698PubMed publication ID24072780
P5875ResearchGate publication ID257136153

P50authorZbigniew ZaslonaQ57167919
Marc Peters-GoldenQ82192734
P2093author name stringKatsuhide Okunishi
Angela J DeGraaf
P2860cites workmTOR: from growth signal integration to cancer, diabetes and ageingQ24633662
Collaborative interactions between neutrophil elastase and metalloproteinases in extracellular matrix degradation in three-dimensional collagen gelsQ24806806
Regulation of immune responses by prostaglandin E2Q26849305
COX-2 expression and cell cycle progression in human fibroblastsQ28184985
Prostaglandin E(2) inhibits collagen expression and proliferation in patient-derived normal lung fibroblasts via E prostanoid 2 receptor and cAMP signaling.Q53594811
Differential regulation by leukotrienes and calcium of Fc gamma receptor-induced phagocytosis and Syk activation in dendritic cells versus macrophages.Q53629779
The differential effect of prostaglandin E2 on transforming growth factor-beta and insulin-induced collagen formation in lung fibroblastsQ69542548
Intracellular degradation of newly synthesized collagenQ71606664
Leukotrienes enhance the bactericidal activity of alveolar macrophages against Klebsiella pneumoniae through the activation of NADPH oxidaseQ28574027
Attenuation of mammalian target of rapamycin activity by increased cAMP in 3T3-L1 adipocytesQ30472934
Fibrotic myofibroblasts manifest genome-wide derangements of translational controlQ33369846
Prostaglandin E(2) induces fibroblast apoptosis by modulating multiple survival pathways.Q33613235
Building collagen molecules, fibrils, and suprafibrillar structures.Q34133305
Cultured lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis have a diminished capacity to synthesize prostaglandin E2 and to express cyclooxygenase-2.Q34211740
Modulation of alveolar macrophage-driven fibroblast proliferation by alternative macrophage mediatorsQ34525796
TGFβ- and bleomycin-induced extracellular matrix synthesis is mediated through Akt and mammalian target of rapamycin (mTOR)Q35041204
In vitro and in vivo characterization of PF-04418948, a novel, potent and selective prostaglandin EP₂ receptor antagonistQ35636109
Common and unique mechanisms regulate fibrosis in various fibroproliferative diseasesQ35649473
Prostaglandin E2 promotes intestinal tumor growth via DNA methylationQ35742739
Prostaglandin E2 suppresses antifungal immunity by inhibiting interferon regulatory factor 4 function and interleukin-17 expression in T cells.Q35907174
A unifying model for mTORC1-mediated regulation of mRNA translation.Q35945036
Prostaglandin E(2) inhibits fibroblast migration by E-prostanoid 2 receptor-mediated increase in PTEN activityQ35973067
Prostanoid EP₁ receptors mediate up-regulation of the orphan nuclear receptor Nurr1 by cAMP-independent activation of protein kinase A, CREB and NF-κB.Q36158964
Prostaglandin E₂ increases fibroblast gene-specific and global DNA methylation via increased DNA methyltransferase expressionQ36183709
Different effects of growth factors on proliferation and matrix production of normal and fibrotic human lung fibroblastsQ36279948
Ribosomal protein S6 phosphorylation: from protein synthesis to cell size.Q36470315
The translational landscape of mTOR signalling steers cancer initiation and metastasisQ36873513
The macrophage: past, present and futureQ36986722
Putting on the brakes: cyclic AMP as a multipronged controller of macrophage functionQ37521452
Ribosomal protein S6 kinase from TOP mRNAs to cell sizeQ37726439
cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity.Q38657890
Cyclic AMP controls mTOR through regulation of the dynamic interaction between Rheb and phosphodiesterase 4D.Q39656356
Dynamic state of collagen: pathways of collagen degradation in vivo and their possible role in regulation of collagen massQ39756963
Epac1-induced cellular proliferation in prostate cancer cells is mediated by B-Raf/ERK and mTOR signaling cascadesQ39804717
Identification of cAMP-dependent kinase as a third in vivo ribosomal protein S6 kinase in pancreatic beta-cellsQ39859443
Prostaglandin E2 inhibits specific lung fibroblast functions via selective actions of PKA and Epac-1.Q39990887
Depletion of type IA regulatory subunit (RIalpha) of protein kinase A (PKA) in mammalian cells and tissues activates mTOR and causes autophagic deficiencyQ40233725
Modulation of collagen and MMP-1 gene expression in fibroblasts by the immunosuppressive drug rapamycin. A direct role as an antifibrotic agent?Q40242728
cAMP-elevating agents and adenylyl cyclase overexpression promote an antifibrotic phenotype in pulmonary fibroblasts.Q40568376
Resistance to Fas-mediated apoptosis in human lung fibroblastQ40706480
Prostaglandin E(2) inhibits fibroblast chemotaxisQ40775240
The antifibrotic effects of plasminogen activation occur via prostaglandin E2 synthesis in humans and miceQ40794888
Augmentation of functional prostaglandin E levels on the respiratory epithelial surface by aerosol administration of prostaglandin E.Q41138646
Collagen: scaffold for repair or executionQ41418665
Discordant regulation of human type I collagen genes by prostaglandin E2Q41627947
SHP-2 regulates cell growth by controlling the mTOR/S6 kinase 1 pathwayQ42831977
Adrenocorticotrophic hormone stimulates phosphotyrosine phosphatase SHP2 in bovine adrenocortical cells: phosphorylation and activation by cAMP-dependent protein kinaseQ42998099
Prostaglandin E2 inhibits fibroblast to myofibroblast transition via E. prostanoid receptor 2 signaling and cyclic adenosine monophosphate elevation.Q44435135
Stimulation of renin release by prostaglandin E2 is mediated by EP2 and EP4 receptors in mouse kidneysQ44869335
Human alveolar macrophage inhibition of lung fibroblast growth. A prostaglandin-dependent processQ50233076
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectprostaglandin E2Q416554
P304page(s)56-66
P577publication date2013-09-26
P1433published inFASEB JournalQ520194
P1476titleInhibition of protein translation as a novel mechanism for prostaglandin E2 regulation of cell functions
P478volume28

Reverse relations

cites work (P2860)
Q92069090Antibiotic pretreatment alleviates liver transplant damage in mice and humans
Q50879214Distinct PKA regulatory subunits mediate PGE2 inhibition of TGFβ-1-stimulated collagen I translation and myofibroblast differentiation.
Q53528564Low-Dose Aspirin Acetylates Cyclooxygenase-1 in Human Colorectal Mucosa: Implications for the Chemoprevention of Colorectal Cancer.
Q38944697Nutritional status-dependent endocannabinoid signalling regulates the integration of rat visceral information
Q34103733Prostaglandin E2 reduces Toll-like receptor 4 expression in alveolar macrophages by inhibition of translation
Q36549053Reversal of the Transcriptome by Prostaglandin E2 during Myofibroblast Dedifferentiation
Q56978001Special Delivery: A New Package for an Old Anti-Fibrotic Mediator

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