Engaging neuroscience to advance translational research in brain barrier biology.

scientific article published in March 2011

Engaging neuroscience to advance translational research in brain barrier biology. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1038/NRN2995
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/nrn2995
P932PMC publication ID3335275
P698PubMed publication ID21331083
P5875ResearchGate publication ID49845434

P50authorGert FrickerQ1515184
Edward NeuweltQ88044074
Costantino IadecolaQ37345166
Damir JanigroQ37378626
Luc LeybaertQ38321237
Christoph FahlkeQ39064875
Zoltán MolnárQ41787890
Norman SaundersQ42706836
P2093author name stringRyan J Watts
John T Povlishock
Danica Stanimirovic
Björn Bauer
Martha E O'Donnell
Frank Sharp
Lester R Drewes
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Paroxysmal exercise-induced dyskinesia and epilepsy is due to mutations in SLC2A1, encoding the glucose transporter GLUT1.Q24648494
A two-hit mechanism causes cerebral cavernous malformations: complete inactivation of CCM1, CCM2 or CCM3 in affected endothelial cellsQ24654323
Newly expressed SUR1-regulated NC(Ca-ATP) channel mediates cerebral edema after ischemic strokeQ24657830
Plasmodium falciparum-infected erythrocytes decrease the integrity of human blood-brain barrier endothelial cell monolayers.Q47826421
Leukoencephalopathy upon disruption of the chloride channel ClC-2.Q48136769
Inflammation and dephosphorylation of the tight junction protein occludin in an experimental model of multiple sclerosisQ48141342
Breast cancer resistance protein (Bcrp1/Abcg2) in mouse placenta and yolk sac: ontogeny and its regulation by progesteroneQ48157062
Efflux mechanisms at the developing brain barriers: ABC-transporters in the fetal and postnatal rat.Q48199790
Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch typeQ48265529
Oxidative stress activates protein tyrosine kinase and matrix metalloproteinases leading to blood-brain barrier dysfunctionQ48299419
Polymorphism in the P-glycoprotein drug transporter MDR1 gene: a possible link between environmental and genetic factors in Parkinson's diseaseQ48320745
Tumor necrosis factor alpha and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrierQ48355279
FGF2 plays a key role in embryonic cerebrospinal fluid trophic properties over chick embryo neuroepithelial stem cells.Q48444602
In vivo activation of human pregnane X receptor tightens the blood-brain barrier to methadone through P-glycoprotein up-regulation.Q48473453
Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans.Q48476417
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The biphasic opening of the blood-brain barrier to proteins following temporary middle cerebral artery occlusion.Q48564690
The development of a blood-brain barrier mechanism in foetal sheep.Q48567457
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Rapid modulation of P-glycoprotein-mediated transport at the blood-brain barrier by tumor necrosis factor-alpha and lipopolysaccharide.Q48702178
Cellular transfer of macromolecules across the developing choroid plexus of Monodelphis domestica.Q48762501
Association of a polymorphism in the ABCB1 gene with Parkinson's disease.Q48765631
Quantitative evaluation of blood-brain barrier permeability following middle cerebral artery occlusion in rats.Q48863137
Profiling neurotransmitter receptor expression in mouse gonadotropin-releasing hormone neurons using green fluorescent protein-promoter transgenics and microarrays.Q48924425
Pathological features of cerebral cortical capillaries are doubled in Alzheimer's disease and Parkinson's disease.Q52024534
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Methionine sulfoximine, a glutamine synthetase inhibitor, attenuates increased extracellular potassium activity during acute hyperammonemiaQ71934058
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Cortical layer 1 and layer 2/3 astrocytes exhibit distinct calcium dynamics in vivoQ27301015
Astrocyte-endothelial interactions at the blood-brain barrierQ28131675
Occludin expression in microvessels of neoplastic and non-neoplastic human brainQ28202259
Size-selective loosening of the blood-brain barrier in claudin-5-deficient miceQ28203769
The optogenetic catechismQ28261583
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Tissue-type plasminogen activator is a regulator of monocyte diapedesis through the brain endothelial barrierQ28291314
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The cerebral effects of ascent to high altitudesQ28307435
Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculatureQ28509331
Expression of aquaporin 1 and aquaporin 4 water channels in rat choroid plexusQ28571861
Dexamethasone increases expression and activity of multidrug resistance transporters at the rat blood-brain barrierQ28572624
Wnt/beta-catenin signaling is required for CNS, but not non-CNS, angiogenesisQ28594356
Expression and localization of Na-driven Cl-HCO(3)(-) exchanger (SLC4A8) in rodent CNSQ28594378
Mechanisms of angiogenesisQ29547485
Molecular regulation of vessel maturationQ29614540
Tripartite synapses: glia, the unacknowledged partnerQ29615224
The blood-brain barrier/neurovascular unit in health and diseaseQ29616335
The blood-brain barrier in health and chronic neurodegenerative disordersQ29616411
Astrocytes, from brain glue to communication elements: the revolution continuesQ29619493
Microglia: a sensor for pathological events in the CNSQ29620556
GLUT1 mutations are a cause of paroxysmal exertion-induced dyskinesias and induce hemolytic anemia by a cation leakQ30481800
A stem cell niche for intermediate progenitor cells of the embryonic cortexQ30488100
A role for leukocyte-endothelial adhesion mechanisms in epilepsyQ30488791
Molecular imaging of proteins in tissues by mass spectrometryQ30489516
Canavan disease: a review of recent developmentsQ30661903
The rat blood-brain barrier transcriptomeQ33227764
The blood-brain barrier is continuously open for several weeks following transient focal cerebral ischemiaQ33325824
Induction of blood brain barrier tight junction protein alterations by CD8 T cellsQ33363111
Chapter 11: Imaging fluorescent mice in vivo using confocal microscopyQ33396874
Does pilocarpine-induced epilepsy in adult rats require status epilepticus?Q33463300
Superparamagnetic iron oxide nanoparticles: diagnostic magnetic resonance imaging and potential therapeutic applications in neurooncology and central nervous system inflammatory pathologies, a reviewQ33503551
Molecular imaging of glioblastoma multiforme using anti-insulin-like growth factor-binding protein-7 single-domain antibodiesQ33722980
The mouse blood-brain barrier transcriptome: a new resource for understanding the development and function of brain endothelial cellsQ33741896
Physiology and pathology of the blood-brain barrier: implications for microbial pathogenesis, drug delivery and neurodegenerative disordersQ33797048
Matrix metalloproteinases in intracerebral hemorrhageQ37282893
Cerebral microvascular endothelial cell Na/H exchange: evidence for the presence of NHE1 and NHE2 isoforms and regulation by arginine vasopressinQ37298011
ABCG2 is upregulated in Alzheimer's brain with cerebral amyloid angiopathy and may act as a gatekeeper at the blood-brain barrier for Abeta(1-40) peptides.Q37351212
Matrix metalloproteinases and their multiple roles in neurodegenerative diseasesQ37375110
Astrocytes and the regulation of cerebral blood flowQ37375326
Biphasic cytoarchitecture and functional changes in the BBB induced by chronic inflammatory painQ37483383
Excitatory amino acid transporters as potential drug targets.Q37489935
Developmentally regulated mannose 6-phosphate receptor-mediated transport of a lysosomal enzyme across the blood-brain barrierQ37494188
Water transport between CNS compartments: contributions of aquaporins and cotransporters.Q37599016
T cell-microglial dialogue in Parkinson's disease and amyotrophic lateral sclerosis: are we listening?Q37625319
Water transport between CNS compartments: functional and molecular interactions between aquaporins and ion channelsQ37660649
Biopharmaceutical drug targeting to the brainQ37671828
Modeling the neurovascular niche: implications for recovery from CNS injury.Q37677445
Connecting vascular and nervous system development: angiogenesis and the blood-brain barrierQ37724330
Functions of astrocytes and their potential as therapeutic targetsQ37794378
Regulation of ABC transporters at the blood-brain barrier: new targets for CNS therapyQ37806476
ABC transporters in the CNS - an inventoryQ37813717
Effects of chronic continuous hypoxia on the expression of SLC4A8 (NDCBE) in neonatal versus adult mouse brainQ39321427
The development of the human blood-brain and blood-CSF barriersQ39746567
Label-free biomedical imaging with high sensitivity by stimulated Raman scattering microscopyQ39903580
Glucocorticoids regulate the human occludin gene through a single imperfect palindromic glucocorticoid response elementQ39941479
A novel cell wall-anchored peptidoglycan hydrolase (autolysin), IspC, essential for Listeria monocytogenes virulence: genetic and proteomic analysisQ39965413
Targeting prostaglandin E2 EP1 receptors prevents seizure-associated P-glycoprotein up-regulationQ39973896
Glucocorticoids increase VE-cadherin expression and cause cytoskeletal rearrangements in murine brain endothelial cEND cellsQ40019129
Hypothetical roles of angiogenesis, osmotic swelling, and ischemia in high-altitude cerebral edemaQ40433868
A neurogenic basis for acute altitude illnessQ40743787
Effects of acute hypoxia on intracellular-pH regulation in astrocytes cultured from rat hippocampusQ40881860
Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neurogliaQ41677354
Astrocyte leptin receptor (ObR) and leptin transport in adult-onset obese miceQ36692057
Mammalian aquaporins: diverse physiological roles and potential clinical significanceQ36697752
Blood-brain barrier breakdown as a therapeutic target in traumatic brain injuryQ36763899
Inflammatory cell migration into the central nervous system: a few new twists on an old taleQ36771887
Cell-cell signaling in the neurovascular unitQ36801092
Glutamate and monoamine transporters: new visions of form and functionQ36825439
Chemotherapy delivery issues in central nervous system malignancy: a reality check.Q36835363
Contribution of carrier-mediated transport systems to the blood-brain barrier as a supporting and protecting interface for the brain; importance for CNS drug discovery and developmentQ36874299
Angiogenesis in brain tumoursQ36887534
Cerebral blood flow and cerebral edema in rats with diabetic ketoacidosisQ36906302
Glial regulation of the cerebral microvasculatureQ36983682
Reperfusion activates metalloproteinases that contribute to neurovascular injuryQ36986393
Role of ATP-binding cassette transporters in brain lipid transport and neurological diseaseQ36987318
Blood-brain barrier: structural components and function under physiologic and pathologic conditionsQ37015412
Natalizumab: targeting alpha4-integrins in multiple sclerosisQ37030428
Strategies to advance translational research into brain barriersQ37037950
Modulation of P-glycoprotein at the blood-brain barrier: opportunities to improve central nervous system pharmacotherapyQ37080236
Functional effectiveness of the blood-brain barrier to small water-soluble molecules in developing and adult opossum (Monodelphis domestica)Q37080750
The blood-CSF barrier explained: when development is not immaturityQ37091976
Stroke program review group: an interim reportQ37097812
VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdownQ37100939
PPARalpha and PPARgamma attenuate HIV-induced dysregulation of tight junction proteins by modulations of matrix metalloproteinase and proteasome activitiesQ37159206
Barriers in the brain: a renaissance?Q37159965
Getting specific: monoclonal antibodies in multiple sclerosis.Q37165875
Review. Structure and mechanism of ATP-binding cassette transportersQ37171513
One of the hottest topics in epileptology: ABC proteins. Their inhibition may be the future for patients with intractable seizuresQ37204397
Neurovascular congruence during cerebral cortical developmentQ37220151
The blood-brain barrier as a cause of obesityQ37232868
Targeting extracellular matrix proteolysis for hemorrhagic complications of tPA stroke therapyQ37232887
Cell adhesion and signaling networks in brain neurovascular unitsQ37251376
Assessment: the use of natalizumab (Tysabri) for the treatment of multiple sclerosis (an evidence-based review): report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of NeurologyQ37259057
Clearance mechanisms of Alzheimer's amyloid-beta peptide: implications for therapeutic design and diagnostic tests.Q37270464
The origins and evolution of "controlled" drug delivery systemsQ37279442
Blood-brain barrier disruption and intra-arterial methotrexate-based therapy for newly diagnosed primary CNS lymphoma: a multi-institutional experienceQ37280734
P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse modelQ41844698
Brain metabolism dictates the polarity of astrocyte control over arteriolesQ42089441
Plasmodium falciparum-infected erythrocytes increase intercellular adhesion molecule 1 expression on brain endothelium through NF-kappaB.Q42408526
Electron microscopy in human hepatic encephalopathyQ42443638
Signaling at the gliovascular interface.Q42451204
Leukocyte-derived matrix metalloproteinase-9 mediates blood-brain barrier breakdown and is proinflammatory after transient focal cerebral ischemiaQ42475527
Aquaporin and blood brain barrierQ42532303
Zebrafish model of the blood-brain barrier: morphological and permeability studiesQ42978242
ABC transporters in cancer: more than just drug efflux pumps.Q43193922
Glucocorticoids induce transactivation of tight junction genes occludin and claudin-5 in retinal endothelial cells via a novel cis-elementQ43212996
Differential expression of the multidrug resistance-related proteins ABCb1 and ABCc1 between blood-brain interfacesQ43617765
Cerebral metabolism of ammonia and amino acids in patients with fulminant hepatic failureQ43777301
Pregnane X receptor (PXR) regulates P-glycoprotein at the blood-brain barrier: functional similarities between pig and human PXR.Q43958807
Arginine vasopressin stimulation of cerebral microvascular endothelial cell Na-K-Cl cotransporter activity is V1 receptor and [Ca] dependentQ44173254
Fibronectin mediates Opc-dependent internalization of Neisseria meningitidis in human brain microvascular endothelial cellsQ44208778
Neuron-to-astrocyte signaling is central to the dynamic control of brain microcirculation.Q44240672
Prevention of seizure-induced up-regulation of endothelial P-glycoprotein by COX-2 inhibitionQ44308080
KRIT1/cerebral cavernous malformation 1 protein localizes to vascular endothelium, astrocytes, and pyramidal cells of the adult human cerebral cortexQ44815936
Rapid regulation of P-glycoprotein at the blood-brain barrier by endothelin-1.Q45025173
Pregnane X receptor up-regulation of P-glycoprotein expression and transport function at the blood-brain barrierQ45025187
Calcium transients in astrocyte endfeet cause cerebrovascular constrictionsQ45051047
The genetics of ATP-binding cassette transportersQ45108337
Blood-brain barrier dysfunction in parkinsonian midbrain in vivoQ45237161
Bumetanide reduces cerebral edema formation in rats with diabetic ketoacidosisQ45242119
Targeting gene-modified hematopoietic cells to the central nervous system: use of green fluorescent protein uncovers microglial engraftment.Q45881740
ABC transporters, cytochromes P450 and their main transcription factors: expression at the human blood-brain barrier.Q46191688
MDR1A (ABCB1)-deficient CF-1 mutant mice are susceptible to cerebral malaria induced by Plasmodium berghei ANKA.Q46273437
The role of the blood-brain barrier Na-K-2Cl cotransporter in stroke.Q46411365
Moderate-to-severe ischemic conditions increase activity and phosphorylation of the cerebral microvascular endothelial cell Na+-K+-Cl- cotransporter.Q46606304
Incidence of brain creatine transporter deficiency in males with developmental delay referred for brain magnetic resonance imagingQ46650603
Glutamate is critically involved in seizure-induced overexpression of P-glycoprotein in the brainQ46659907
Seizure-induced up-regulation of P-glycoprotein at the blood-brain barrier through glutamate and cyclooxygenase-2 signalingQ46840766
Molecular insights and therapeutic targets for blood-brain barrier disruption in ischemic stroke: critical role of matrix metalloproteinases and tissue-type plasminogen activatorQ33823616
Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer's diseaseQ33862071
Regulation of P-glycoprotein and other ABC drug transporters at the blood-brain barrierQ33900889
P-Glycoprotein, a gatekeeper in the blood-brain barrierQ33904245
Drug resistance in brain diseases and the role of drug efflux transporters.Q33988704
Enhanced astrocytic Ca2+ signals contribute to neuronal excitotoxicity after status epilepticusQ34048890
Studies of the development of brain barrier systems to lipid insoluble molecules in fetal sheepQ34053029
Plasmodium falciparum-infected erythrocytes induce NF-kappaB regulated inflammatory pathways in human cerebral endotheliumQ34078957
Celecoxib treatment restores pharmacosensitivity in a rat model of pharmacoresistant epilepsy.Q34112939
Constitutive androstane receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrierQ34128009
Activation of PKC isoform beta(I) at the blood-brain barrier rapidly decreases P-glycoprotein activity and enhances drug delivery to the brainQ34171206
The science of stroke: mechanisms in search of treatmentsQ34212337
A dynamic switch between inhibitory and excitatory currents in a neuronal glutamate transporterQ34245054
Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis.Q34341174
The overlap between neurodegenerative and vascular factors in the pathogenesis of dementiaQ34402033
Common mechanisms of nerve and blood vessel wiringQ34433723
Contribution of vasogenic and cellular edema to traumatic brain swelling measured by diffusion-weighted imagingQ34447920
Astrocyte-mediated control of cerebral blood flowQ34481040
Aryl hydrocarbon receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrierQ34502705
Leptin signaling, adiposity, and energy balanceQ34524449
Aquaporins in brain: distribution, physiology, and pathophysiologyQ34580267
Angiotensin II controls occludin function and is required for blood brain barrier maintenance: relevance to multiple sclerosisQ34666702
Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammationQ34683399
Amnionless (AMN) mutations in Imerslund-Gräsbeck syndrome may be associated with disturbed vitamin B12 transport into the CNS.Q34734010
Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depressionQ34740072
An alpha-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brainQ34763571
Complex phenotype of mice lacking occludin, a component of tight junction strands.Q34781594
Imaging individual mRNA molecules using multiple singly labeled probesQ34833213
Glucose transporter deficiency syndrome (GLUT1DS) and the ketogenic dietQ34892668
Angiogenic factors in the central nervous systemQ35207666
Effects on the visual system might contribute to some of the cognitive deficits of cancer chemotherapy-induced 'chemo-fog'.Q35645883
Alexander disease: putative mechanisms of an astrocytic encephalopathyQ35652990
Neurotransmitter transporters: why dance with so many partners?Q35690225
Equivocal roles of tissue-type plasminogen activator in stroke-induced injuryQ35704593
Alzheimer disease: mechanistic understanding predicts novel therapiesQ35750804
Targeted delivery of proteins across the blood-brain barrierQ35762072
Apolipoprotein E-epsilon4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's diseaseQ35774045
From structure to disease: the evolving tale of aquaporin biologyQ35875999
Regulation of brain aquaporinsQ35961491
Neurobarrier coupling in the brain: a partner of neurovascular and neurometabolic coupling?Q36022927
Neurovascular mechanisms of Alzheimer's neurodegenerationQ36088588
Positron emission tomography studies on binding of central nervous system drugs and P-glycoprotein function in the rodent brain.Q36136731
The excitatory amino acid transporters: pharmacological insights on substrate and inhibitor specificity of the EAAT subtypesQ36236149
Multiple sclerosis -- a coordinated immune attack across the blood brain barrierQ36268418
From angiogenesis to neuropathologyQ36342360
Physiology and pathophysiology of Na+/H+ exchange and Na+ -K+ -2Cl- cotransport in the heart, brain, and blood.Q36399226
STAT1 signaling modulates HIV-1-induced inflammatory responses and leukocyte transmigration across the blood-brain barrierQ36445840
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research.Q36457107
Astrocyte control of synaptic transmission and neurovascular coupling.Q36525563
Phosphorylation of claudin-5 and occludin by rho kinase in brain endothelial cells.Q36559702
Diverse roles of matrix metalloproteinases and tissue inhibitors of metalloproteinases in neuroinflammation and cerebral ischemia.Q36644315
Glial cell aquaporin-4 overexpression in transgenic mice accelerates cytotoxic brain swelling.Q36678507
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectneuroscienceQ207011
P304page(s)169-182
P577publication date2011-03-01
P1433published inNature Reviews NeuroscienceQ2108225
P1476titleEngaging neuroscience to advance translational research in brain barrier biology
P478volume12

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Q93046744MicroRNA-126-3p Attenuates Intracerebral Hemorrhage-Induced Blood-Brain Barrier Disruption by Regulating VCAM-1 Expression
Q39164361MicroRNAs regulate human brain endothelial cell-barrier function in inflammation: implications for multiple sclerosis.
Q36588683Modeling the blood-brain barrier using stem cell sources
Q27306725Molecular characterisation of transport mechanisms at the developing mouse blood-CSF interface: a transcriptome approach
Q37523317Molecular contributions to neurovascular unit dysfunctions after brain injuries: lessons for target-specific drug development
Q38163889Monocarboxylate transporters in temporal lobe epilepsy: roles of lactate and ketogenic diet
Q36655374Mrp1 is essential for sphingolipid signaling to p-glycoprotein in mouse blood-brain and blood-spinal cord barriers
Q34104503Nanomaterial-mediated CNS delivery of diagnostic and therapeutic agents
Q38522125Nanoneurotherapeutics approach intended for direct nose to brain delivery.
Q36812347Nanoparticle transport across the blood brain barrier.
Q60303358Nanoparticle-conjugated nutraceuticals exert prospectively palliative of amyloid aggregation
Q35558668Nanoparticles enhance brain delivery of blood-brain barrier-impermeable probes for in vivo optical and magnetic resonance imaging
Q30843116Neural Crest Cells Contribute an Astrocyte-like Glial Population to the Spleen.
Q26995185Neural stem cell niches in health and diseases
Q37396577Neural stem cell-mediated enzyme/prodrug therapy for glioma: preclinical studies
Q37976564Neurological diseases in relation to the blood-brain barrier
Q36330297Neurovascular dysfunction and faulty amyloid β-peptide clearance in Alzheimer disease
Q37270697Neurovascular matrix metalloproteinases and the blood-brain barrier
Q29615839Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
Q51745613Non-invasive vagus nerve stimulation reduces blood-brain barrier disruption in a rat model of ischemic stroke.
Q41037865Novel Therapeutic Effects of Leonurine On Ischemic Stroke: New Mechanisms of BBB Integrity
Q47249148One-week exposure to a free-choice high-fat high-sugar diet does not disrupt blood-brain barrier permeability in fed or overnight fasted rats.
Q37358086Optimizing superparamagnetic iron oxide nanoparticles as drug carriers using an in vitro blood-brain barrier model
Q38058369Overview and introduction: the blood-brain barrier in health and disease
Q48478445P2X7 receptors mediate innate phagocytosis by human neural precursor cells and neuroblasts.
Q57287906Pantoprazole Induces Mitochondrial Apoptosis and Attenuates NF-κB Signaling in Glioma Cells
Q27690845Pathophysiology of the neurovascular unit: disease cause or consequence?
Q30835318Pericytes from Mesenchymal Stem Cells as a model for the blood-brain barrier.
Q41853014Pharmacological modulation of blood-brain barrier increases permeability of doxorubicin into the rat brain
Q26861408Physiology and pathophysiology of the blood-brain barrier: P-glycoprotein and occludin trafficking as therapeutic targets to optimize central nervous system drug delivery
Q48474979Prenatal high-fat diet alters the cerebrovasculature and clearance of β-amyloid in adult offspring.
Q30746065Presymptomatic activation of the PDGF-CC pathway accelerates onset of ALS neurodegeneration.
Q51758262Pretreatment with Shuanghe-Tang Extract Attenuates Postischemic Brain Injury and Edema in a Mouse Model of Stroke: An Analysis of Medicinal Herbs Listed in Dongui Bogam.
Q26778701Promising approaches to circumvent the blood-brain barrier: progress, pitfalls and clinical prospects in brain cancer
Q50532471Prospects for strain-specific immunotherapy in Alzheimer's disease and tauopathies.
Q48375562Protective effect of telmisartan on neurovascular unit and inflammasome in stroke-resistant spontaneously hypertensive rats
Q36534816Rapid endothelial cytoskeletal reorganization enables early blood-brain barrier disruption and long-term ischaemic reperfusion brain injury
Q35143491Rapid transport within cerebral perivascular spaces underlies widespread tracer distribution in the brain after intranasal administration.
Q30359368Real-time monitoring of human blood-brain barrier disruption
Q27342762Reduced Contextual Discrimination following Alcohol Consumption or MDMA Administration in Mice
Q36460596Restraint Stress-Induced Morphological Changes at the Blood-Brain Barrier in Adult Rats
Q39205654Retinoic acid induces blood-brain barrier development.
Q28081507Rho kinase as a target for cerebral vascular disorders
Q36007494Selective increase of two ABC drug efflux transporters at the blood-spinal cord barrier suggests induced pharmacoresistance in ALS.
Q89800666Sequential Targeting in Crosslinking Nanotheranostics for Tackling the Multibarriers of Brain Tumors
Q30519560Sialic acid deposition impairs the utility of AAV9, but not peptide-modified AAVs for brain gene therapy in a mouse model of lysosomal storage disease
Q35164692Significance of ubiquitin carboxy-terminal hydrolase L1 elevations in athletes after sub-concussive head hits
Q90402270Sijunzi decoction may decrease apoptosis via stabilization of the extracellular matrix following cerebral ischaemia-reperfusion in rats
Q38269392Smuggling Drugs into the Brain: An Overview of Ligands Targeting Transcytosis for Drug Delivery across the Blood-Brain Barrier
Q46434436Spaceflight-Induced Intracranial Hypertension and Visual Impairment: Pathophysiology and Countermeasures
Q39457984Stem cell therapy for abrogating stroke-induced neuroinflammation and relevant secondary cell death mechanisms
Q37998107Strategies to minimize CNS toxicity: in vitro high-throughput assays and computational modeling
Q38239646Systemic inflammation, blood-brain barrier vulnerability and cognitive/non-cognitive symptoms in Alzheimer disease: relevance to pathogenesis and therapy
Q38937398Systems-level thinking for nanoparticle-mediated therapeutic delivery to neurological diseases
Q97540667TIMP1 preserves the blood-brain barrier through interacting with CD63/integrin β 1 complex and regulating downstream FAK/RhoA signaling
Q38190042TREK-king the blood-brain-barrier
Q36962238Tanycytic VEGF-A boosts blood-hypothalamus barrier plasticity and access of metabolic signals to the arcuate nucleus in response to fasting
Q64108410The Blood-Brain Barrier Breakdown During Acute Phase of the Pilocarpine Model of Epilepsy Is Dynamic and Time-Dependent
Q30466613The Long and the Short of it: Gene and Environment Interactions During Early Cortical Development and Consequences for Long-Term Neurological Disease
Q64968356The Role of Antibodies and Their Receptors in Protection Against Ordered Protein Assembly in Neurodegeneration.
Q38745356The Role of Nanoparticle in Brain Permeability: An in-vitro BBB Model
Q36877518The Science of Vascular Contributions to Cognitive Impairment and Dementia (VCID): A Framework for Advancing Research Priorities in the Cerebrovascular Biology of Cognitive Decline
Q38407992The Use of Anthracyclines for Therapy of CNS Tumors.
Q35864850The adverse effects of air pollution on the nervous system
Q26753140The biological significance of brain barrier mechanisms: help or hindrance in drug delivery to the central nervous system?
Q35909425The blood-brain barrier is disrupted in a mouse model of infantile neuronal ceroid lipofuscinosis: amelioration by resveratrol
Q38134725The blood-brain barrier: an engineering perspective.
Q48854235The influence of distributional kinetics into a peripheral compartment on the pharmacokinetics of substrate partitioning between blood and brain tissue.
Q55514994The meningeal and choroidal infiltration routes for leukocytes in stroke.
Q57190123The need for research on human brain development
Q38195949The neurovascular unit - concept review
Q27006033The pathobiology of vascular dementia
Q34534371The vasculome of the mouse brain
Q90420762Theoretical Prediction of the Complex P-Glycoprotein Substrate Efflux Based on the Novel Hierarchical Support Vector Regression Scheme
Q57071940Theranostic applications of nanoparticles in neurodegenerative disorders
Q39479822Theranostic implications of nanotechnology in multiple sclerosis: a future perspective.
Q36731242Translational Stroke Research on Blood-Brain Barrier Damage: Challenges, Perspectives, and Goals.
Q26830912Traumatic brain injury, neuroinflammation, and post-traumatic headaches
Q48348672Treatment of penetrating brain injury in a rat model using collagen scaffolds incorporating soluble Nogo receptor
Q28539271Ultrasound-mediated blood-brain barrier disruption for targeted drug delivery in the central nervous system
Q28072473Utilizing pharmacotherapy and mesenchymal stem cell therapy to reduce inflammation following traumatic brain injury
Q48016461Validation by Magnetic Resonance Imaging of the Diagnostic Potential of a Heptapeptide-Functionalized Imaging Probe Targeted to Amyloid-β and Able to Cross the Blood-Brain Barrier
Q37480076Vascular Contributions to Cognitive Impairment and Treatments with Traditional Chinese Medicine.
Q33639014Vascular neural network phenotypic transformation after traumatic injury: potential role in long-term sequelae
Q50534038Vascular tight junction disruption and angiogenesis in spontaneously hypertensive rat with neuroinflammatory white matter injury.
Q26781557Vasculoprotection as a Convergent, Multi-Targeted Mechanism of Anti-AD Therapeutics and Interventions
Q55439840Vitexin reduces epilepsy after hypoxic ischemia in the neonatal brain via inhibition of NKCC1.
Q90082196XingNaoJing injections protect against cerebral ischemia/reperfusion injury and alleviate blood-brain barrier disruption in rats, through an underlying mechanism of NLRP3 inflammasomes suppression
Q26748774miRNAs Participate in MS Pathological Processes and Its Therapeutic Response

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