Reperfusion activates metalloproteinases that contribute to neurovascular injury

scientific article published on 15 December 2007

Reperfusion activates metalloproteinases that contribute to neurovascular injury is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.EXPNEUROL.2007.12.003
P932PMC publication ID2588410
P698PubMed publication ID18187134
P5875ResearchGate publication ID5663894

P50authorThomas TomsickQ87999626
P2093author name stringJoseph F Clark
Pooja Khatri
Joseph P Broderick
Aigang Lu
Frank R Sharp
Ruiqiong Ran
Gail J Pyne-Geithman
Kenneth R Wagner
P2860cites workSafety of mechanical thrombectomy and intravenous tissue plasminogen activator in acute ischemic stroke. Results of the multi Mechanical Embolus Removal in Cerebral Ischemia (MERCI) trial, part IQ28246214
Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trialQ28257163
Role of gelatinase B and elastase in human polymorphonuclear neutrophil migration across basement membraneQ28292489
S-nitrosylation of matrix metalloproteinases: signaling pathway to neuronal cell deathQ30843579
Matrix metalloproteinase 2 gene knockout has no effect on acute brain injury after focal ischemia.Q31014494
Mild hypothermia enhances the neuroprotective effects of FK506 and expands its therapeutic window following transient focal ischemia in ratsQ33202946
Cortical spreading depression activates and upregulates MMP-9.Q33785624
Zymographic techniques for the analysis of matrix metalloproteinases and their inhibitorsQ34389230
Extracellular proteolysis in brain injury and inflammation: role for plasminogen activators and matrix metalloproteinasesQ34733026
Neuroprotective efficacy and therapeutic time window of peroxynitrite decomposition catalysts in focal cerebral ischemia in ratsQ35047316
Mechanisms, challenges and opportunities in strokeQ35120144
Cerebral microvessel responses to focal ischemiaQ35193869
Matrix metalloproteinase inhibition prevents oxidative stress-associated blood-brain barrier disruption after transient focal cerebral ischemiaQ40672673
Matrix metalloproteinases increase very early during experimental focal cerebral ischemiaQ41671816
Preferential inactivation of tissue inhibitor of metalloproteinases-1 that is bound to the precursor of matrix metalloproteinase 9 (progelatinase B) by human neutrophil elastase.Q41677243
Leukocyte-derived matrix metalloproteinase-9 mediates blood-brain barrier breakdown and is proinflammatory after transient focal cerebral ischemiaQ42475527
Estimation of gelatinase content in rat brain: effect of focal ischemiaQ42496551
Ischaemic damage of brain microvessels: inherent risks for thrombolytic treatment in strokeQ42912296
Geldanamycin induces heat shock proteins in brain and protects against focal cerebral ischemiaQ44027708
Phosphodiesterase 4 inhibitor cilomilast inhibits fibroblast-mediated collagen gel degradation induced by tumor necrosis factor-alpha and neutrophil elastaseQ44160776
Closure of the blood-brain barrier by matrix metalloproteinase inhibition reduces rtPA-mediated mortality in cerebral ischemia with delayed reperfusionQ44509868
Neuronal activity-dependent increase of net matrix metalloproteinase activity is associated with MMP-9 neurotoxicity after kainate.Q44597441
Neutrophil elastase processing of gelatinase A is mediated by extracellular matrixQ46153137
Early appearance of activated matrix metalloproteinase-9 and blood-brain barrier disruption in mice after focal cerebral ischemia and reperfusionQ48087981
Neutrophil infiltration increases matrix metalloproteinase-9 in the ischemic brain after occlusion/reperfusion of the middle cerebral artery in ratsQ48121683
Nitric oxide synthetase activity in cerebral post-ischemic reperfusion and effects of L-N(G)-nitroarginine and 7-nitroindazole on the survivalQ48164897
Topographically graded postischemic presence of metalloproteinases is inhibited by hypothermiaQ48220254
Hemorrhagic transformation is related to the duration of occlusion and treatment with tissue plasminogen activator in a nonembolic stroke modelQ48250404
Matrix metalloproteinases and TIMPs are associated with blood-brain barrier opening after reperfusion in rat brainQ48384389
Increased brain expression of matrix metalloproteinase-9 after ischemic and hemorrhagic human stroke.Q48543834
Zymographic measurement of gelatinase activity in brain tissue after detergent extraction and affinity-support purificationQ48616876
Expression and activation of matrix metalloproteinase-2 and -9 in rat brain after transient focal cerebral ischemiaQ48758937
Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia.Q48785632
Rapid expression of neuronal and inducible nitric oxide synthases during post-ischemic reperfusion in rat brainQ48924526
Mild to moderate hypothermia prevents microvascular basal lamina antigen loss in experimental focal cerebral ischemia.Q51026546
Timing of Spontaneous Recanalization and Risk of Hemorrhagic Transformation in Acute Cardioembolic StrokeQ60669998
Inactivation of tissue inhibitor of metalloproteinases by neutrophil elastase and other serine proteinasesQ67918893
Impairment and restoration of the endothelial blood-brain barrier in the rat cerebral infarction model assessed by expression of endothelial barrier antigen immunoreactivityQ73421752
Plasminogen activation in focal cerebral ischemia and reperfusionQ73500476
Quantitative assessment of the normal cerebral microvasculature by endothelial barrier antigen (EBA) immunohistochemistry: application to focal cerebral ischemiaQ73815694
Elements of cerebral microvascular ischaemiaQ74410287
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)549-559
P577publication date2007-12-15
P1433published inExperimental NeurologyQ5421127
P1476titleReperfusion activates metalloproteinases that contribute to neurovascular injury
P478volume210

Reverse relations

cites work (P2860)
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Q48783900Decreased infarct volume and intracranial hemorrhage associated with intra-arterial nonionic iso-osmolar contrast material in an MCA occlusion/reperfusion model
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Q38645205Matrix Metalloproteinase in Blood-Brain Barrier Breakdown in Dementia
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