Dose dependence and therapeutic window for the neuroprotective effects of 17beta-estradiol when administered after cerebral ischemia

scientific article published on 14 February 2007

Dose dependence and therapeutic window for the neuroprotective effects of 17beta-estradiol when administered after cerebral ischemia is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.NEULET.2007.01.074
P932PMC publication ID1936945
P698PubMed publication ID17331646
P5875ResearchGate publication ID6474327

P2093author name stringQing Liu
Ran Liu
Shao-Hua Yang
James W Simpkins
Xiaofei Wang
P2860cites work17-beta estradiol can reduce secondary ischemic damage and mortality of subarachnoid hemorrhageQ30652313
17beta-estradiol reduces stroke injury in estrogen-deficient female animalsQ30750600
Postischemic estrogen reduces hypoperfusion and secondary ischemia after experimental strokeQ30982945
Estrogens decrease reperfusion-associated cortical ischemic damage: an MRI analysis in a transient focal ischemia modelQ30985069
Estradiol protects against ischemic injuryQ31978205
Estrogen-mediated neuroprotection after experimental stroke in male ratsQ32038461
Estrogen as a neuroprotectant in strokeQ33898014
Neuroprotective effects of estrogens: potential mechanisms of actionQ33922344
Estrogen receptor alpha, not beta, is a critical link in estradiol-mediated protection against brain injuryQ34114102
Cellular and molecular mechanisms of estrogen regulation of memory function and neuroprotection against Alzheimer's disease: recent insights and remaining challengesQ34272405
17-beta estradiol protects neurons from oxidative stress-induced cell death in vitroQ34289335
The use of estrogens and related compounds in the treatment of damage from cerebral ischemia.Q35679182
Mitochondria play a central role in estrogen-induced neuroprotection.Q36050615
The potential role for estrogen replacement therapy in the treatment of the cognitive decline and neurodegeneration associated with Alzheimer's disease.Q40496639
Neuroprotective effects of a novel non-receptor-binding estrogen analogue: in vitro and in vivo analysisQ40699740
The nonfeminizing enantiomer of 17beta-estradiol exerts protective effects in neuronal cultures and a rat model of cerebral ischemiaQ40834022
Effects of 17beta-estradiol on glucose transporter 1 expression and endothelial cell survival following focal ischemia in the ratsQ42448906
Cerebral white matter is highly vulnerable to ischemiaQ42522490
Neuroprotective effects of estradiol in middle-aged female ratsQ43516260
Nongenomic antiapoptotic signal transduction by estrogen in cultured cortical neuronsQ43629583
Ovarian hormones elicit phosphorylation of Akt and extracellular-signal regulated kinase in explants of the cerebral cortex.Q43667398
Proestrus levels of estradiol during transient global cerebral ischemia improves the histological outcome of the hippocampal CA1 region: perfusion-dependent and-independent mechanismsQ43854048
17 beta-Estradiol enhances the outgrowth and survival of neocortical neurons in cultureQ44563705
Estradiol modulates bcl-2 in cerebral ischemia: a potential role for estrogen receptorsQ48157309
Comparative distribution of estrogen receptor-alpha and -beta mRNA in the rat central nervous systemQ48590882
Estrogens may reduce mortality and ischemic damage caused by middle cerebral artery occlusion in the female rat.Q48605497
Estradiol treatment increases viability of glioma and neuroblastoma cells in vitro.Q55481886
Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid beta-peptide toxicity in hippocampal neuronsQ71464474
Stroke in estrogen receptor-alpha-deficient miceQ73505612
Estradiol exerts neuroprotective effects when administered after ischemic insultQ73505615
Estrogen and Bcl-2: gene induction and effect of transgene in experimental strokeQ74538262
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectcerebral infarctionQ1209150
P1104number of pages5
P304page(s)237-241
P577publication date2007-02-14
P1433published inNeuroscience LettersQ7002625
P1476titleDose dependence and therapeutic window for the neuroprotective effects of 17beta-estradiol when administered after cerebral ischemia
P478volume415

Reverse relations

cites work (P2860)
Q3649231517β-Estradiol reappropriates mass lost to the hypermetabolic state in thermally injured rats
Q33523047Acute administration of non-classical estrogen receptor agonists attenuates ischemia-induced hippocampal neuron loss in middle-aged female rats
Q48618953Buyang Huanwu Decoction () reduces infarct volume and enhances estradiol and estradiol receptor concentration in ovariectomized rats after middle cerebral artery occlusion
Q33714865Combination therapy of 17beta-estradiol and recombinant tissue plasminogen activator for experimental ischemic stroke
Q36658310Comparison of Two Methods of Estradiol Replacement: their Physiological and Behavioral Outcomes
Q33541716Different methods for administering 17beta-estradiol to ovariectomized rats result in opposite effects on ischemic brain damage
Q37490810Dose-related neuroprotective versus neurodamaging effects of estrogens in rat cerebral ischemia: a systematic analysis
Q83469201Effect of different doses of estrogen on the nigrostriatal dopaminergic system in two 6-hydroxydopamine-induced lesion models of Parkinson's disease
Q34295673Estradiol attenuates ischemia-induced death of hippocampal neurons and enhances synaptic transmission in aged, long-term hormone-deprived female rats
Q37414220Estrogen treatment following severe burn injury reduces brain inflammation and apoptotic signaling
Q36931700High-dose estrogen treatment at reperfusion reduces lesion volume and accelerates recovery of sensorimotor function after experimental ischemic stroke.
Q43636914Long-term effects of post-ischaemic oestrogen on brain injury in a rat transient forebrain ischaemia model
Q51427094Methods for 17β-oestradiol administration to rats.
Q38005895Neuroprotection and estrogen receptors
Q37069818Neuroprotective action of acute estrogens: animal models of brain ischemia and clinical implications
Q34827433Neuroprotective actions of estradiol and novel estrogen analogs in ischemia: translational implications
Q46343776Order of magnitude differences between methods for maintaining physiological 17beta-oestradiol concentrations in ovariectomized rats
Q27012615Revisiting the timing hypothesis: biomarkers that define the therapeutic window of estrogen for stroke
Q36185871Sex, stroke, and inflammation: the potential for estrogen-mediated immunoprotection in stroke
Q38285856Sex- and gender-specific research priorities in cardiovascular resuscitation: proceedings from the 2014 Academic Emergency Medicine Consensus Conference Cardiovascular Resuscitation Research Workgroup
Q26992041Stroke: understanding the differences between males and females
Q35892631The Protective Effect of Human Umbilical Cord Blood CD34+ Cells and Estradiol against Focal Cerebral Ischemia in Female Ovariectomized Rat: Cerebral MR Imaging and Immunohistochemical Study
Q38796711Why estrogens matter for behavior and brain health

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