Potent induction of tumor immunity by combining tumor cryoablation with anti-CTLA-4 therapy

scientific article published on 22 November 2011

Potent induction of tumor immunity by combining tumor cryoablation with anti-CTLA-4 therapy is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1158/0008-5472.CAN-11-1782
P932PMC publication ID4526218
P698PubMed publication ID22108823

P50authorJames P. AllisonQ6140731
Anne E TrumbleQ56891561
Larry NortonQ37644083
P2093author name stringStephen B Solomon
Rebecca Waitz
Marcella Fassò
Elena N Petre
P2860cites workImmunologic response to cryoablation of breast cancerQ40446167
In situ tumor ablation creates an antigen source for the generation of antitumor immunityQ40550098
In vivo destruction of tumor tissue by cryoablation can induce inhibition of secondary tumor growth: an experimental studyQ40808256
Combination immunotherapy of primary prostate cancer in a transgenic mouse model using CTLA-4 blockade.Q41735884
Tumor vaccines expressing flt3 ligand synergize with ctla-4 blockade to reject preimplanted tumorsQ42051381
Characterization of prostatic epithelial cell lines derived from transgenic adenocarcinoma of the mouse prostate (TRAMP) model.Q42815729
Granulocyte macrophage colony-stimulating factor--secreting allogeneic cellular immunotherapy for hormone-refractory prostate cancerQ46252104
Epitope landscape in breast and colorectal cancer.Q51894674
Imiquimod enhances the systemic immunity attained by local cryosurgery destruction of melanoma lesions.Q51976721
Adoptive immunotherapy of breast cancer with lymph node cells primed by cryoablation of the primary tumor.Q53599386
Comparative immunological studies in rats following cryosurgery and surgical excision of 3-methylcholanthrene-induced primary autochthonous tumors.Q54516265
Immune-mediated inhibition of metastases after treatment with local radiation and CTLA-4 blockade in a mouse model of breast cancerQ56903097
Antitumor effects of residual tumor after cryoablation: the combined effect of residual tumor and a protein-bound polysaccharide on multiple liver metastases in a murine modelQ57105366
Mechanisms of tissue injury in cryosurgeryQ57108848
Synergy between In situ Cryoablation and TLR9 Stimulation Results in a Highly Effective In vivo Dendritic Cell VaccineQ58620026
Enhanced tumor metastases in rats following cryosurgery of primary tumorQ70451622
Cryosurgical ablation of the normal ventral prostate plus adjuvant does not protect Copenhagen rats from Dunning prostatic adenocarcinoma challengeQ73709122
Control of regulatory T cell development by the transcription factor Foxp3Q27860489
Improved Survival with Ipilimumab in Patients with Metastatic MelanomaQ27861062
Enhancement of antitumor immunity by CTLA-4 blockadeQ28275730
Investigation of the mechanism and the effect of cryoimmunology in the Copenhagen rat.Q33945419
Targeted cryoablation of the prostate: 7-year outcomes in the primary treatment of prostate cancerQ34147128
Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancerQ34210036
Remission of Metastatic Lesions Following Cryosurgery in Prostatic Cancer: Immunologic ConsiderationsQ34225753
Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunityQ34334817
Prostate cancer in a transgenic mouseQ34444393
Potentiating endogenous antitumor immunity to prostate cancer through combination immunotherapy with CTLA4 blockade and GM-CSF.Q34657928
CTLA-4 blockade synergizes with tumor-derived granulocyte-macrophage colony-stimulating factor for treatment of an experimental mammary carcinoma.Q36284594
Comparison of cryoablation, radiofrequency ablation and high-intensity focused ultrasound for treating small renal tumoursQ36312844
Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompQ36375152
SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockadeQ36491182
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patientsQ36498459
Efficient loading of dendritic cells following cryo and radiofrequency ablation in combination with immune modulation induces anti-tumour immunity.Q36611772
Cost analysis of open, laparoscopic, and percutaneous treatment options for nephron-sparing surgeryQ36649050
Elimination of residual metastatic prostate cancer after surgery and adjunctive cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) blockade immunotherapy.Q36780750
Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanomaQ36853440
Image-guided percutaneous cryoablation of renal tumors.Q37028498
Cyclophosphamide unmasks an antimetastatic effect of local tumor cryoablationQ37268005
Cryo-immunology: a review of the literature and proposed mechanisms for stimulatory versus suppressive immune responsesQ37325106
Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodiesQ39828440
CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cellsQ40266751
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)430-439
P577publication date2011-11-22
P1433published inCancer ResearchQ326097
P1476titlePotent induction of tumor immunity by combining tumor cryoablation with anti-CTLA-4 therapy
P478volume72

Reverse relations

cites work (P2860)
Q37509479A Pilot Study of Preoperative Single-Dose Ipilimumab and/or Cryoablation in Women with Early-Stage Breast Cancer with Comprehensive Immune Profiling
Q41928232A Review of Immune Therapy in Cancer and a Question: Can Thermal Therapy Increase Tumor Response?
Q37658308Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas
Q34617627Beyond the androgen receptor: new approaches to treating metastatic prostate cancer. Report of the 2013 Prouts Neck Prostate Cancer Meeting
Q53028366Breaking immune tolerance by targeting CD25+ regulatory T cells is essential for the anti-tumor effect of the CTLA-4 blockade in an HLA-DR transgenic mouse model of prostate cancer.
Q26992295CTLA-4 blockade in tumor models: an overview of preclinical and translational research
Q42214233CTLA-4 blockade synergizes with cryoablation to mediate tumor rejection
Q38171573Cancer immunotherapy using tumor cryoablation
Q50100688Checkpoint inhibitors in triple-negative breast cancer (TNBC): Where to go from here
Q38760734Combination Therapy with Anti-PD-1, Anti-TIM-3, and Focal Radiation Results in Regression of Murine Gliomas
Q38665664Combined Blockade of T Cell Immunoglobulin and Mucin Domain 3 and Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Results in Durable Therapeutic Efficacy in Mice with Intracranial Gliomas
Q56892705Combining immune check-point blockade and cryoablation in an immunocompetent hormone sensitive murine model of prostate cancer
Q39738697Controlling melanoma at local and systemic levels: is a combination of ablative therapy and immunotherapy the way forward?
Q35184986Cryo-ablation improves anti-tumor immunity through recovering tumor educated dendritic cells in tumor-draining lymph nodes
Q90681174Cryoablation and Immunotherapy: An Enthralling Synergy to Confront the Tumors
Q36597502Cryoablation and Meriva have strong therapeutic effect on triple-negative breast cancer
Q64051980Cryoablation and immunotherapy: an overview of evidence on its synergy
Q60045474Cryotherapy for nodal metastasis in NSCLC with acquired resistance to immunotherapy
Q34288183Cryotherapy with concurrent CpG oligonucleotide treatment controls local tumor recurrence and modulates HER2/neu immunity.
Q37340661Deep Sequencing of T-cell Receptor DNA as a Biomarker of Clonally Expanded TILs in Breast Cancer after Immunotherapy
Q51556518Defeating Cancers' Adaptive Defensive Strategies Using Thermal Therapies: Examining Cancer's Therapeutic Resistance, Ablative, and Computational Modeling Strategies as a means for Improving Therapeutic Outcome.
Q55257766Dendritic cell activation enhances anti-PD-1 mediated immunotherapy against glioblastoma.
Q89356407Developing a Roadmap for Interventional Oncology
Q34919077Elimination of metastatic melanoma using gold nanoshell-enabled photothermal therapy and adoptive T cell transfer
Q38184650Emerging immunotherapy strategies in breast cancer
Q36723747Enhanced Anti-Tumor Efficacy through a Combination of Integrin αvβ6-Targeted Photodynamic Therapy and Immune Checkpoint Inhibition
Q35178939Enhancement of T cell recruitment and infiltration into tumours.
Q24629841Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma
Q37701177Ginsenoside Rh2 enhances the antitumor immunological response of a melanoma mice model
Q60948054HLA-A2-Restricted Epitopes Identified from MTA1 Could Elicit Antigen-Specific Cytotoxic T Lymphocyte Response
Q38596007Harnessing the immunomodulatory effect of thermal and non-thermal ablative therapies for cancer treatment
Q34205626Image-guided thermal ablation of tumors increases the plasma level of interleukin-6 and interleukin-10.
Q64091327Immune Checkpoint Inhibitors in Hepatocellular Carcinoma: Opportunities and Challenges
Q38816839Immune Checkpoint Therapies in Prostate Cancer
Q42690545Immuno-thermal ablations - boosting the anticancer immune response
Q90009896Immunological Targets for Immunotherapy: Inhibitory T Cell Receptors
Q30354580Immunological effect of local ablation combined with immunotherapy on solid malignancies.
Q34444291Immunological responses triggered by photothermal therapy with carbon nanotubes in combination with anti-CTLA-4 therapy to inhibit cancer metastasis
Q47217599Immunomodulation characteristics by thermal ablation therapy in cancer patients
Q36841621Immunomodulatory therapy for melanoma: ipilimumab and beyond
Q52592731Immunotherapy Plus Cryotherapy: Potential Augmented Abscopal Effect for Advanced Cancers.
Q90229263Immunotherapy and the Interventional Oncologist: Challenges and Opportunities-A Society of Interventional Oncology White Paper
Q38180749Immunotherapy for malignant pleural mesothelioma. Current status and future prospects
Q38413904Immunotherapy in Cancer: A Combat between Tumors and the Immune System; You Win Some, You Lose Some
Q49571153Incorporating Radiation Oncology into Immunotherapy: proceedings from the ASTRO-SITC-NCI immunotherapy workshop
Q89721163Induction of antitumor immunity in mice by the combination of nanoparticle-based photothermolysis and anti-PD-1 checkpoint inhibition
Q58559604Interventional Oncology: Treatment of primary liver tumors and liver metastases. Part II: non-nuclear techniques
Q39325230Intratracheal and oral administration of SM-276001: a selective TLR7 agonist, leads to antitumor efficacy in primary and metastatic models of cancer
Q38069640Ipilimumab in prostate cancer
Q26822491Local tumour ablative therapies: opportunities for maximising immune engagement and activation
Q55191920Matched T cell repertoire analysis of peripheral blood and tumor-infiltrating lymphocytes (TILs) in early stage breast cancer (ESBC) patients (pts) treated with pre-operative cryoablation (cryo) and/or Ipilimumab (Ipi).
Q26781522Modulation of APC Function and Anti-Tumor Immunity by Anti-Cancer Drugs
Q35042668New and emerging therapeutic options for malignant pleural mesothelioma: review of early clinical trials
Q90598729Oncolysis without viruses - inducing systemic anticancer immune responses with local therapies
Q40696642Optimized magnitude of cryosurgery facilitating anti-tumor immunoreaction in a mouse model of Lewis lung cancer
Q36657043PD-1 Blockade Boosts Radiofrequency Ablation-Elicited Adaptive Immune Responses against Tumor
Q37156495Percutaneous irreversible electroporation for breast tissue and breast cancer: safety, feasibility, skin effects and radiologic-pathologic correlation in an animal study
Q36170378Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy.
Q64076444Positive Immuno-Modulation Following Radiofrequency Assisted Liver Resection in Hepatocellular Carcinoma
Q54012733Pre-operative immunotherapy with tumor cryoablation (cryo) plus ipilimumab (ipi) induces potentially favorable systemic and intratumoral immune effects in early stage breast cancer (ESBC) patients.
Q38333001Re-purposing cryoablation: a combinatorial 'therapy' for the destruction of tissue
Q48648638Systemic Antitumor Immunity by PD-1/PD-L1 Inhibition Is Potentiated by Vascular-Targeted Photodynamic Therapy of Primary Tumors
Q38103582T-cell tolerance in cancer
Q64934973TLR1/2 ligand enhances antitumor efficacy of CTLA-4 blockade by increasing intratumoral Treg depletion.
Q35136450Targeting multiple key signaling pathways in melanoma using leelamine.
Q26853269Temperature matters! And why it should matter to tumor immunologists
Q38304438The CD28-B7 Family in Anti-Tumor Immunity: Emerging Concepts in Cancer Immunotherapy
Q38724564The future of biology in driving the field of hyperthermia
Q42545786The genesis of Zelboraf: targeting mutant B-Raf in melanoma
Q38987399The microtubule-depolymerizing agent ansamitocin P3 programs dendritic cells toward enhanced anti-tumor immunity.
Q26751230Thermal Ablative Therapies and Immune Checkpoint Modulation: Can Locoregional Approaches Effect a Systemic Response?
Q34406134Thermal ablation of tumours: biological mechanisms and advances in therapy.
Q30363372Thermal and mechanical high-intensity focused ultrasound: perspectives on tumor ablation, immune effects and combination strategies.
Q37246484Transient regulatory T cell ablation deters oncogene-driven breast cancer and enhances radiotherapy
Q39212591Tremelimumab in combination with ablation in patients with advanced hepatocellular carcinoma
Q37685855Vaccination with tumor cells expressing IL-15 and IL-15Rα inhibits murine breast and prostate cancer.

Search more.