| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2001PNAS...98.6144C |
| P356 | DOI | 10.1073/PNAS.101596998 |
| P932 | PMC publication ID | 33436 |
| P698 | PubMed publication ID | 11344272 |
| P5875 | ResearchGate publication ID | 235612015 |
| P50 | author | Hyongjong Koh | Q59693519 |
| P2093 | author name string | J Kim | |
| J Chung | |||
| J Lee | |||
| S Kim | |||
| C Kim | |||
| J H Lee | |||
| D Kim | |||
| K S Cho | |||
| P2860 | cites work | Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor | Q22009126 |
| Direct control of the Forkhead transcription factor AFX by protein kinase B | Q22009452 | ||
| Phosphorylation and activation of p70s6k by PDK1 | Q24323433 | ||
| 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase | Q24336639 | ||
| A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans | Q24603590 | ||
| Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery | Q27860586 | ||
| 90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1. | Q27863657 | ||
| Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast | Q27936949 | ||
| PDK1 homologs activate the Pkc1-mitogen-activated protein kinase pathway in yeast | Q27940222 | ||
| Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B | Q28116107 | ||
| Rho GTPase control of protein kinase C-related protein kinase activation by 3-phosphoinositide-dependent protein kinase | Q28141177 | ||
| NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase | Q28144326 | ||
| NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling | Q28144330 | ||
| Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt | Q28255373 | ||
| Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1 | Q28283323 | ||
| Regulation of cell death protease caspase-9 by phosphorylation | Q28288607 | ||
| Regulation of protein kinase C zeta by PI 3-kinase and PDK-1 | Q28567633 | ||
| Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha | Q28616168 | ||
| Regulation of neuronal survival by the serine-threonine protein kinase Akt | Q29614185 | ||
| A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback | Q29618324 | ||
| Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt. | Q30452681 | ||
| Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway | Q30829981 | ||
| Cellular signaling: pivoting around PDK-1. | Q34073383 | ||
| 3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro | Q34452063 | ||
| Ectopic gene expression in Drosophila using GAL4 system | Q34470107 | ||
| Transgenic inhibitors identify two roles for protein kinase A in Drosophila development. | Q34606886 | ||
| The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth. | Q35915951 | ||
| Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase | Q36103541 | ||
| Phosphorylation and activation of cAMP-dependent protein kinase by phosphoinositide-dependent protein kinase | Q36278250 | ||
| A modular misexpression screen in Drosophila detecting tissue-specific phenotypes | Q37239712 | ||
| Genetic control of programmed cell death in Drosophila | Q38468332 | ||
| Further evidence that 3-phosphoinositide-dependent protein kinase-1 (PDK1) is required for the stability and phosphorylation of protein kinase C (PKC) isoforms. | Q40842389 | ||
| Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB. | Q40913396 | ||
| Induction of NF-kappaB by the Akt/PKB kinase | Q40950127 | ||
| The PI 3-kinase/Akt signaling pathway delivers an anti-apoptotic signal. | Q41120735 | ||
| Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB. | Q41128352 | ||
| Mechanisms and consequences of activation of protein kinase B/Akt | Q41751003 | ||
| Extracellular zinc activates p70 S6 kinase through the phosphatidylinositol 3-kinase signaling pathway | Q42800851 | ||
| Genetic analysis of protein kinase B (AKT) in Drosophila | Q47070510 | ||
| Drosophila S6 kinase: a regulator of cell size | Q47072437 | ||
| A Schizosaccharomyces pombe gene, ksg1, that shows structural homology to the human phosphoinositide-dependent protein kinase PDK1, is essential for growth, mating and sporulation | Q47982081 | ||
| The Drosophila segment polarity gene patched is involved in a position-signalling mechanism in imaginal discs. | Q52448652 | ||
| The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells | Q57272881 | ||
| Akt is more than just a Bad kinase | Q59068251 | ||
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Drosophila | Q312154 |
| apoptotic process | Q14599311 | ||
| Phosphoinositide-dependent kinase 1 Dmel_CG1210 | Q29809746 | ||
| P1104 | number of pages | 6 | |
| P304 | page(s) | 6144-6149 | |
| P577 | publication date | 2001-05-08 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Drosophila phosphoinositide-dependent kinase-1 regulates apoptosis and growth via the phosphoinositide 3-kinase-dependent signaling pathway | |
| P478 | volume | 98 |
| Q34243953 | A screen for genes expressed in the olfactory organs of Drosophila melanogaster identifies genes involved in olfactory behaviour |
| Q47206708 | Body size in Drosophila: genetic architecture, allometries and sexual dimorphism |
| Q33607484 | Cracking open cell death in the Drosophila ovary |
| Q36246003 | Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia |
| Q37057398 | Discrete Functions of TRAF1 and TRAF2 in Drosophila melanogaster Mediated by c-Jun N-Terminal Kinase and NF-κB-Dependent Signaling Pathways |
| Q34325514 | Drosophila PDZ-GEF, a guanine nucleotide exchange factor for Rap1 GTPase, reveals a novel upstream regulatory mechanism in the mitogen-activated protein kinase signaling pathway |
| Q36855041 | Ecological Trade-offs between Migration and Reproduction Are Mediated by the Nutrition-Sensitive Insulin-Signaling Pathway. |
| Q24534217 | Essential role of PDK1 in regulating cell size and development in mice |
| Q28509286 | Essential role of PDK1 in regulating endothelial cell migration |
| Q64243704 | Evolutionary rate covariation analysis of E-cadherin identifies Raskol as a regulator of cell adhesion and actin dynamics in Drosophila |
| Q24794099 | Expression of Drosophila FOXO regulates growth and can phenocopy starvation |
| Q37214956 | Genetics and molecular biology of tuberous sclerosis complex |
| Q43693180 | Identification of tyrosine phosphorylation sites on 3-phosphoinositide-dependent protein kinase-1 and their role in regulating kinase activity |
| Q57284407 | Insulin and 20-hydroxyecdysone oppose each other in the regulation of phosphoinositide-dependent kinase-1 expression during insect pupation |
| Q34417182 | Insulin signaling: lessons from the Drosophila tuberous sclerosis complex, a tumor suppressor |
| Q33292483 | Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1. |
| Q46463399 | Isolation of gene sets affected specifically by polyglutamine expression: implication of the TOR signaling pathway in neurodegeneration |
| Q47072494 | JNK pathway mediates apoptotic cell death induced by tumor suppressor LKB1 in Drosophila |
| Q36222098 | MKP-3 has essential roles as a negative regulator of the Ras/mitogen-activated protein kinase pathway during Drosophila development |
| Q27329700 | Molecular characterization of the Haemonchus contortus phosphoinositide-dependent protein kinase-1 gene (Hc-pdk-1). |
| Q33714405 | Nuclear translocation of 3'-phosphoinositide-dependent protein kinase 1 (PDK-1): a potential regulatory mechanism for PDK-1 function. |
| Q41788576 | Nutrition-responsive glia control exit of neural stem cells from quiescence. |
| Q40973885 | PDK1 plays a vital role on hematopoietic stem cell function. |
| Q45098656 | PDK1 regulates cell proliferation and cell cycle progression through control of cyclin D1 and p27Kip1 expression |
| Q33952857 | PDK1 regulates growth through Akt and S6K in Drosophila |
| Q24297416 | PDK1, the master regulator of AGC kinase signal transduction |
| Q34389540 | PKB/AKT: functional insights from genetic models |
| Q50977901 | PTEN, Longevity and Age-Related Diseases. |
| Q33900458 | Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila |
| Q28588541 | Pdk1 activity controls proliferation, survival, and growth of developing pancreatic cells |
| Q35031770 | Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm |
| Q28565877 | Requirement of 3-phosphoinositide-dependent protein kinase-1 for BDNF-mediated neuronal survival |
| Q41838163 | Serratia marcescens induces apoptotic cell death in host immune cells via a lipopolysaccharide- and flagella-dependent mechanism |
| Q34988459 | Signaling from Akt to FRAP/TOR targets both 4E-BP and S6K in Drosophila melanogaster |
| Q40170225 | The SARS-Coronavirus Membrane protein induces apoptosis through modulating the Akt survival pathway |
| Q34430813 | The coupling of cell growth to the cell cycle. |
| Q37694347 | The hypoxia-induced paralogs Scylla and Charybdis inhibit growth by down-regulating S6K activity upstream of TSC in Drosophila |
| Q40561467 | The in vivo role of PtdIns(3,4,5)P3 binding to PDK1 PH domain defined by knockin mutation |
| Q24297392 | The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1 |
| Q28083445 | The role of insulin/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogaster |
| Q33390615 | Toll mediated infection response is altered by gravity and spaceflight in Drosophila. |
| Q90317229 | Triacylglycerol Metabolism in Drosophila melanogaster |
| Q84934427 | WITHDRAWN: Increase in phosphorylation of PDK1 and cell survival after acute spinal cord injury |
| Q36491816 | dAkt kinase controls follicle cell size during Drosophila oogenesis |
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