| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.1016/S0070-2153(04)62006-0 |
| P698 | PubMed publication ID | 15522742 |
| P50 | author | Sean McLean | Q43627648 |
| P2093 | author name string | Robert P Mecham | |
| Cassandra M Kelleher | |||
| P2860 | cites work | Absence of basement membranes after targeting the LAMC1 gene results in embryonic lethality due to failure of endoderm differentiation | Q22008650 |
| A single EFEMP1 mutation associated with both Malattia Leventinese and Doyne honeycomb retinal dystrophy | Q22009991 | ||
| COL5A1 exon 14 splice acceptor mutation causes a functional null allele, haploinsufficiency of alpha 1(V) and abnormal heterotypic interstitial fibrils in Ehlers-Danlos syndrome II | Q24291045 | ||
| Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo | Q24292210 | ||
| The association of human fibulin-1 with elastic fibers: an immunohistological, ultrastructural, and RNA study | Q24306799 | ||
| An elastin gene mutation producing abnormal tropoelastin and abnormal elastic fibres in a patient with autosomal dominant cutis laxa | Q24314373 | ||
| Thrombospondin-4 and its variants: expression and differential effects on endothelial cells | Q24319267 | ||
| Genetic heterogeneity of cutis laxa: a heterozygous tandem duplication within the fibulin-5 (FBLN5) gene | Q24532116 | ||
| COL5A1 haploinsufficiency is a common molecular mechanism underlying the classical form of EDS | Q24540243 | ||
| Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1 | Q24672489 | ||
| The fibulin-1 gene (FBLN1) is disrupted in a t(12;22) associated with a complex type of synpolydactyly | Q24679520 | ||
| Mice that lack thrombospondin 2 display connective tissue abnormalities that are associated with disordered collagen fibrillogenesis, an increased vascular density, and a bleeding diathesis | Q24683656 | ||
| SPARC, a matricellular glycoprotein with important biological functions | Q28138199 | ||
| Tenascin-C in development and disease: gene regulation and cell function | Q28139238 | ||
| Tenascins: regulation and putative functions during pathological stress | Q28185244 | ||
| Fibulins: a versatile family of extracellular matrix proteins | Q28207887 | ||
| Localization of laminin alpha4-chain in developing and adult human tissues | Q28215564 | ||
| Fibulin-5/DANCE is essential for elastogenesis in vivo | Q28216334 | ||
| Homozygosity for a missense mutation in fibulin-5 (FBLN5) results in a severe form of cutis laxa | Q28218665 | ||
| Identification of the proteoglycan versican in aorta and smooth muscle cells by DNA sequence analysis, in situ hybridization and immunohistochemistry | Q28238318 | ||
| Lumican regulates collagen fibril assembly: skin fragility and corneal opacity in the absence of lumican | Q28272368 | ||
| Developmental regulation of the laminin alpha5 chain suggests a role in epithelial and endothelial cell maturation | Q28505309 | ||
| Morphofunctional studies of the glomerular wall in mice lacking entactin-1 | Q28508173 | ||
| EVEC, a novel epidermal growth factor-like repeat-containing protein upregulated in embryonic and diseased adult vasculature | Q28575376 | ||
| Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascular development | Q28588213 | ||
| The absence of nidogen 1 does not affect murine basement membrane formation | Q28588236 | ||
| Deletion of the laminin alpha4 chain leads to impaired microvessel maturation | Q28589136 | ||
| Tenascin-X deficiency mimics Ehlers-Danlos syndrome in mice through alteration of collagen deposition | Q28590272 | ||
| Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system | Q28591291 | ||
| EMILIN-1 deficiency induces elastogenesis and vascular cell defects | Q28594647 | ||
| Emilin, a component of elastic fibers preferentially located at the elastin-microfibrils interface | Q28610088 | ||
| Ehlers-Danlos syndrome type VIIA and VIIB result from splice-junction mutations or genomic deletions that involve exon 6 in theCOL1A1 andCOL1A2 genes of type I collagen | Q57197822 | ||
| Central Roles of α 5 β 1 Integrin and Fibronectin in Vascular Development in Mouse Embryos and Embryoid Bodies | Q61960709 | ||
| A novel extracellular membrane elaborated by a mouse embryonal carcinoma-derived cell line | Q67051136 | ||
| Expression of fibronectin variants in vascular and visceral smooth muscle cells in development | Q68536570 | ||
| Localization of collagen types I, III, IV and V, fibronectin and laminin in human arteries by the indirect immunofluorescence method | Q68919337 | ||
| Aortic elastin abnormalities in osteogenesis imperfecta type II | Q69747789 | ||
| Light microscopic immunolocation of thrombospondin in human tissues | Q69886611 | ||
| The effect of developing hypertension on the synthesis and accumulation of elastin in the aorta of the rat | Q70042874 | ||
| Transmural organization of the arterial media. The lamellar unit revisited | Q70048173 | ||
| Nidogen: a new, self-aggregating basement membrane protein | Q70462480 | ||
| Distribution of SPARC in normal and neoplastic human tissue | Q71922754 | ||
| The distribution of collagen types I, III and V (AB) in normal and atherosclerotic human aorta | Q72136795 | ||
| Elastogenesis in human aorta: An electron microscopic study | Q72606325 | ||
| Autosomal dominant supravalvular aortic stenosis: localization to chromosome 7 | Q72909952 | ||
| Phenotypic alteration of vascular smooth muscle cells precedes elastolysis in a mouse model of Marfan syndrome | Q73348165 | ||
| Cartilage oligomeric matrix protein (thrombospondin-5) is expressed by human vascular smooth muscle cells | Q73366277 | ||
| Fibulin-2 expression marks transformed mesenchymal cells in developing cardiac valves, aortic arch vessels, and coronary vessels | Q74381823 | ||
| Expression of lumican in thickened intima and smooth muscle cells in human coronary atherosclerosis | Q77757716 | ||
| Morphogenesis of the first blood vessels | Q77902911 | ||
| Electron microscopy of elastic arteries; the thoracic aorta of the rat | Q78859905 | ||
| Electron microscopy of the newborn rat aorta | Q79460319 | ||
| Cell adhesion and integrin binding to recombinant human fibrillin-1 | Q28610091 | ||
| Mechanisms of angiogenesis and arteriogenesis | Q29617257 | ||
| Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome | Q29618845 | ||
| Identification of a novel marker for primordial smooth muscle and its differential expression pattern in contractile vs noncontractile cells | Q30442152 | ||
| Regulation of differentiation of vascular smooth muscle cells | Q30464387 | ||
| Development of the aortic vessel wall as defined by vascular smooth muscle and extracellular matrix markers | Q30469176 | ||
| The EMILIN protein family | Q30610055 | ||
| An electron microscope study of the aorta in young and in aging mice | Q30989419 | ||
| Antisense inhibition of decorin expression in myoblasts decreases cell responsiveness to transforming growth factor beta and accelerates skeletal muscle differentiation | Q31546720 | ||
| Smooth muscle cell origin and its relation to heterogeneity in development and disease | Q33682707 | ||
| An open reading frame element mediates posttranscriptional regulation of tropoelastin and responsiveness to transforming growth factor beta1. | Q33959906 | ||
| Fibrillin: from domain structure to supramolecular assembly | Q34078143 | ||
| Genetic disorders of the elastic fiber system | Q34078147 | ||
| Mouse models of genetic diseases resulting from mutations in elastic fiber proteins | Q34078150 | ||
| A recessive form of the Ehlers-Danlos syndrome caused by tenascin-X deficiency | Q34098081 | ||
| Haploinsufficiency for one COL3A1 allele of type III procollagen results in a phenotype similar to the vascular form of Ehlers-Danlos syndrome, Ehlers-Danlos syndrome type IV. | Q34113108 | ||
| Matricellular proteins: extracellular modulators of cell function | Q34149511 | ||
| SPARC, a matricellular protein: at the crossroads of cell-matrix communication | Q34164765 | ||
| Fibulins: physiological and disease perspectives. | Q34250587 | ||
| Differential expression of fibrillin-3 adds to microfibril variety in human and avian, but not rodent, connective tissues | Q34298597 | ||
| Null alleles of the COL5A1 gene of type V collagen are a cause of the classical forms of Ehlers-Danlos syndrome (types I and II). | Q34390680 | ||
| Thrombospondins: multifunctional regulators of cell interactions | Q34425129 | ||
| Expression of SPARC during development of the chicken chorioallantoic membrane: evidence for regulated proteolysis in vivo | Q34447297 | ||
| Thrombospondin-1 as an endogenous inhibitor of angiogenesis and tumor growth. | Q34633187 | ||
| Signaling pathways in vascular development | Q34762483 | ||
| Mice deficient in small leucine-rich proteoglycans: novel in vivo models for osteoporosis, osteoarthritis, Ehlers-Danlos syndrome, muscular dystrophy, and corneal diseases | Q34816873 | ||
| Versican: a versatile extracellular matrix proteoglycan in cell biology | Q34858300 | ||
| The role of laminin in embryonic cell polarization and tissue organization | Q35123983 | ||
| Basement membrane assembly, stability and activities observed through a developmental lens. | Q35680487 | ||
| Fibulins in development and heritable disease | Q35726742 | ||
| The lack of thrombospondin-1 (TSP1) dictates the course of wound healing in double-TSP1/TSP2-null mice | Q35789152 | ||
| In vivo expression of mRNA for the Ca++-binding protein SPARC (osteonectin) revealed by in situ hybridization | Q36218019 | ||
| A human vascular disorder, supravalvular aortic stenosis, maps to chromosome 7. | Q36228410 | ||
| Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain | Q36255943 | ||
| Developmental adaptation of the mouse cardiovascular system to elastin haploinsufficiency | Q36524613 | ||
| Localization and activity of lysyl oxidase within nuclei of fibrogenic cells | Q36709638 | ||
| Formation of hyaluronan- and versican-rich pericellular matrix is required for proliferation and migration of vascular smooth muscle cells | Q38326238 | ||
| Perinatal lethality and endothelial cell abnormalities in several vessel compartments of fibulin-1-deficient mice | Q39528556 | ||
| Isolated supravalvular aortic stenosis: functional haploinsufficiency of the elastin gene as a result of nonsense-mediated decay | Q39544531 | ||
| Gene structure and functional analysis of the mouse nidogen-2 gene: nidogen-2 is not essential for basement membrane formation in mice | Q39681020 | ||
| Electron microscopic and cytochemical studies of rat aorta. Intracellular vesicles containing elastin- and collagen-like material | Q40217169 | ||
| Deposition of tropoelastin into the extracellular matrix requires a competent elastic fiber scaffold but not live cells | Q40550378 | ||
| Versican/PG-M G3 domain promotes tumor growth and angiogenesis | Q40591730 | ||
| Elastin: mutational spectrum in supravalvular aortic stenosis. | Q40727660 | ||
| TGF-beta1 binding protein-like modules of fibrillin-1 and -2 mediate integrin-dependent cell adhesion | Q41030329 | ||
| Fibrillin-1 and -2 contain heparin-binding sites important for matrix deposition and that support cell attachment | Q42157069 | ||
| Electron microscopic study of the prenatal development of the thoracic aorta in the rat. | Q42519088 | ||
| Decreased biglycan expression and differential decorin localization in human abdominal aortic aneurysms | Q44205488 | ||
| Capillary changes in skeletal muscle of patients with Ullrich's disease with collagen VI deficiency | Q44433821 | ||
| Elastin and collagen accumulation in rabbit ascending aorta and pulmonary trunk during postnatal growth. Correlation of cellular synthetic response with medial tension | Q45218889 | ||
| A Lamellar Unit of Aortic Medial Structure and Function in Mammals | Q47714030 | ||
| Leucine-rich repeat glycoproteins of the extracellular matrix | Q47970508 | ||
| Overlapping, complementary and site-specific expression pattern of genes of the EMILIN/Multimerin family. | Q48011032 | ||
| Changes in the vascular extracellular matrix during embryonic vasculogenesis and angiogenesis | Q48117290 | ||
| Differential expression of thrombospondin 1, 2, and 3 during murine development | Q48292673 | ||
| Targetting of the gene encoding fibrillin-1 recapitulates the vascular aspect of Marfan syndrome. | Q52192356 | ||
| Onset of elastogenesis and downregulation of smooth muscle actin as distinguishing phenomena in artery differentiation in the chick embryo. | Q52198834 | ||
| Vascularization of the mouse embryo: A study of flk‐1, tek, tie, and vascular endothelial growth factor expression during development | Q52208633 | ||
| Multiple phenotypically distinct smooth muscle cell populations exist in the adult and developing bovine pulmonary arterial media in vivo. | Q52213848 | ||
| Collagen VI deficiency induces early onset myopathy in the mouse: an animal model for Bethlem myopathy. | Q52532612 | ||
| Domains in tropoelastin that mediate elastin deposition in vitro and in vivo. | Q54126494 | ||
| Embryonic lethal mutation in mouse collagen I gene causes rupture of blood vessels and is associated with erythropoietic and mesenchymal cell death. | Q54247456 | ||
| Partial COL1A2 gene duplication produces features of osteogenesis imperfecta and Ehlers-Danlos syndrome type VII | Q57197804 | ||
| P921 | main subject | extracellular matrix | Q193825 |
| aorta | Q101004 | ||
| P304 | page(s) | 153-188 | |
| P577 | publication date | 2004-01-01 | |
| P1433 | published in | Current Topics in Developmental Biology | Q15745419 |
| P1476 | title | Vascular extracellular matrix and aortic development | |
| P478 | volume | 62 |
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| Q35653469 | A multi-layered computational model of coupled elastin degradation, vasoactive dysfunction, and collagenous stiffening in aortic aging |
| Q46150198 | Absence of TGFbeta signaling in embryonic vascular smooth muscle leads to reduced lysyl oxidase expression, impaired elastogenesis, and aneurysm |
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| Q38215407 | Cardiovascular manifestations in Marfan syndrome and related diseases; multiple genes causing similar phenotypes |
| Q57472208 | Comparative gene array analyses of severe elastic fiber defects in late embryonic and newborn mouse aorta |
| Q35087070 | Decreased aortic diameter and compliance precedes blood pressure increases in postnatal development of elastin-insufficient mice. |
| Q58804478 | Deletion of ACTA2 in mice promotes angiotensin II induced pathogenesis of thoracic aortic aneurysms and dissections |
| Q33595919 | Design of an elastin-layered dermal regeneration template |
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| Q55053148 | EMILIN-1 regulates the amount of oxytalan fiber formation in periodontal ligaments in vitro. |
| Q36807301 | Echocardiographic Characterization of Postnatal Development in Mice with Reduced Arterial Elasticity |
| Q35159934 | Effect of age and gender on the progression of adult vascular dysfunction in a mouse model of fetal programming lacking endothelial nitric oxide synthase |
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| Q34342434 | Elastogenesis at the onset of human cardiac valve development |
| Q34299648 | Elastogenic protein expression of a highly elastic murine spinal ligament: the ligamentum flavum |
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| Q34644635 | Fibrillins 1 and 2 perform partially overlapping functions during aortic development |
| Q37727885 | Fibulin-5 null mice with decreased arterial compliance maintain normal systolic left ventricular function, but not diastolic function during maturation |
| Q37424201 | Fibulin-5, an integrin-binding matricellular protein: its function in development and disease |
| Q38497456 | Gene expression profiling in acute Stanford type B aortic dissection |
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| Q36730629 | Inhibition of versican expression by siRNA facilitates tropoelastin synthesis and elastic fiber formation by human SK-LMS-1 leiomyosarcoma smooth muscle cells in vitro and in vivo |
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