scholarly article | Q13442814 |
review article | Q7318358 |
P2093 | author name string | Marian F Young | |
Laurent Ameye | |||
P433 | issue | 9 | |
P921 | main subject | osteoarthritis | Q62736 |
osteoporosis | Q165328 | ||
muscular dystrophy | Q1137767 | ||
Ehlers-Danlos syndrome | Q1141499 | ||
P304 | page(s) | 107R-16R | |
P577 | publication date | 2002-09-01 | |
P1433 | published in | Glycobiology | Q5572596 |
P1476 | title | Mice deficient in small leucine-rich proteoglycans: novel in vivo models for osteoporosis, osteoarthritis, Ehlers-Danlos syndrome, muscular dystrophy, and corneal diseases | |
P478 | volume | 12 |
Q35028071 | A 3D cartilage - inflammatory cell culture system for the modeling of human osteoarthritis |
Q43144585 | A central role for decorin during vertebrate convergent extension |
Q35357064 | A mouse model of spontaneous preterm birth based on the genetic ablation of biglycan and decorin |
Q37357861 | Ablation of the decorin gene enhances experimental hepatic fibrosis and impairs hepatic healing in mice. |
Q36876356 | Absence of association of asporin polymorphisms and osteoarthritis susceptibility in US Caucasians |
Q35075082 | Absence of biglycan accelerates the degenerative process in mouse intervertebral disc |
Q42293031 | Absence of fibromodulin affects matrix composition, collagen deposition and cell turnover in healthy and fibrotic lung parenchyma |
Q42291340 | Absence of the dermatan sulfate chain of decorin does not affect mouse development. |
Q33239022 | Activation of genes for growth factor and cytokine pathways late in chondrogenic differentiation of ATDC5 cells |
Q28301787 | An aspartic acid repeat polymorphism in asporin inhibits chondrogenesis and increases susceptibility to osteoarthritis |
Q35574942 | Applications of genomics in the inner ear |
Q58567264 | Association between the aspartic acid D-repeat polymorphisms and osteoarthritis susceptibility: An updated systematic review and meta-analyses |
Q37004976 | BGN Mutations in X-Linked Spondyloepimetaphyseal Dysplasia. |
Q33690385 | Biglycan and decorin differentially regulate signaling in the fetal membranes |
Q36274812 | Biglycan and fibromodulin fragmentation correlates with temporal and spatial annular remodelling in experimentally injured ovine intervertebral discs |
Q24623422 | Biglycan binds to alpha- and gamma-sarcoglycan and regulates their expression during development |
Q24529120 | Biglycan is a new extracellular component of the Chordin-BMP4 signaling pathway |
Q35855912 | Biglycan is an extracellular MuSK binding protein important for synapse stability |
Q35219616 | Biglycan knockout mice: new models for musculoskeletal diseases |
Q38310133 | Biglycan modulates angiogenesis and bone formation during fracture healing |
Q30857848 | Biglycan organizes collagen VI into hexagonal-like networks resembling tissue structures |
Q42684588 | Biglycan regulates the expression and sarcolemmal localization of dystrobrevin, syntrophin, and nNOS. |
Q36481626 | Biglycan: a multivalent proteoglycan providing structure and signals |
Q39755499 | Binding characteristics of the osteoarthritis-associated protein asporin |
Q36798761 | Biological functions of the small leucine-rich proteoglycans: from genetics to signal transduction. |
Q37786597 | Biominerals—hierarchical nanocomposites: the example of bone |
Q35964784 | Bleeding and bruising in patients with Ehlers-Danlos syndrome and other collagen vascular disorders |
Q37524243 | Bone marrow mesenchymal stem cells and TGF-β signaling in bone remodeling |
Q39648114 | Canine tissue-specific expression of multiple small leucine rich proteoglycans |
Q33892064 | Cervical remodeling during pregnancy and parturition |
Q40679886 | Changes in Structural-Mechanical Properties and Degradability of Collagen during Aging-associated Modifications |
Q40081753 | Characterization of collagen II fibrils containing biglycan and their effect as a coating on osteoblast adhesion and proliferation |
Q36713861 | Chondroitin sulfate proteoglycans in tumor progression |
Q34285595 | Chondroitin sulphate proteoglycans: preventing plasticity or protecting the CNS? |
Q36713871 | Chondroitin/Dermatan sulfates in the central nervous system: their structures and functions in health and disease |
Q52014450 | Collagen fibril assembly during postnatal development and dysfunctional regulation in the lumican-deficient murine cornea. |
Q44666610 | Collagen fibril organization in the pregnant endometrium of decorin-deficient mice. |
Q33294967 | Collagen-binding proteoglycan fibromodulin can determine stroma matrix structure and fluid balance in experimental carcinoma |
Q42472134 | Colocalization of the collagen-binding proteoglycans decorin, biglycan, fibromodulin and lumican with different cells in human gingiva |
Q35629851 | Compensatory fetal membrane mechanisms between biglycan and decorin in inflammation. |
Q38659486 | Copy number loss in the region of the ASPN gene in patients with acetabular dysplasia: ASPN CNV in acetabular dysplasia |
Q30344006 | Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan. |
Q40260607 | D14 repeat polymorphism of the asporin gene is associated with primary osteoarthritis of the knee in a Mexican Mestizo population. |
Q24323987 | Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells |
Q50203730 | Decorin and biglycan are necessary for maintaining collagen fibril structure, fiber realignment, and mechanical properties of mature tendons |
Q34439113 | Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels |
Q39905823 | Decorin deficiency in diabetic mice: aggravation of nephropathy due to overexpression of profibrotic factors, enhanced apoptosis and mononuclear cell infiltration. |
Q37956937 | Decorin in atherosclerosis |
Q94468795 | Decorin knockdown affects the gene expression profile of adhesion, growth and extracellular matrix metabolism in C-28/I2 chondrocytes |
Q46287140 | Decorin modulates matrix mineralization in vitro |
Q40518248 | Decorin reduces hypertrophic scarring through inhibition of the TGF-β1/Smad signaling pathway in a rat osteomyelitis model |
Q46644000 | Decorin regulates endothelial cell motility on collagen I through activation of insulin-like growth factor I receptor and modulation of alpha2beta1 integrin activity |
Q40010017 | Decorin transfection induces proteomic and phenotypic modulation in breast cancer cells 8701-BC. |
Q35956255 | Decorin-TGFβ axis in hepatic fibrosis and cirrhosis |
Q37735163 | Decorin-inducible Peg3 Evokes Beclin 1-mediated Autophagy and Thrombospondin 1-mediated Angiostasis |
Q50887032 | Decorin-transforming growth factor- interaction regulates matrix organization and mechanical characteristics of three-dimensional collagen matrices |
Q26772197 | Decorin: A Growth Factor Antagonist for Tumor Growth Inhibition |
Q37374758 | Dermatan sulfate epimerase 1-deficient mice have reduced content and changed distribution of iduronic acids in dermatan sulfate and an altered collagen structure in skin. |
Q41639952 | Development of myotendinous-like junctions that anchor cardiac valves requires fibromodulin and lumican |
Q41845335 | Diamond squid (Thysanoteuthis rhombus)-derived chondroitin sulfate stimulates bone healing within a rat calvarial defect |
Q38542618 | Differential effects of fibromodulin deficiency on mouse mandibular bones and teeth: a micro-CT time course study |
Q46556637 | Distinctive localization and function for lumican, fibromodulin and decorin to regulate collagen fibril organization in periodontal tissues |
Q35925095 | Do Non-collagenous Proteins Affect Skeletal Mechanical Properties? |
Q41916228 | Dysfunctional tendon collagen fibrillogenesis in collagen VI null mice |
Q40629414 | Effect of Function-Enhanced Mesenchymal Stem Cells Infected With Decorin-Expressing Adenovirus on Hepatic Fibrosis |
Q92812229 | Elevated Expression of Lumican in Lung Cancer Cells Promotes Bone Metastasis through an Autocrine Regulatory Mechanism |
Q37163213 | Evidence for a calcification process in the trabecular meshwork |
Q89588107 | Evidence of vasculature and chondrocyte to osteoblast transdifferentiation in craniofacial synovial joints: Implications for osteoarthritis diagnosis and therapy |
Q33705683 | Ex vivo assessment of mouse cervical remodeling through pregnancy via 23Na MRS. |
Q33865933 | Exclusion of biglycan mutations in a cohort of patients with neuromuscular disorders |
Q52648781 | Expression profiling of disease progression in canine model of Duchenne muscular dystrophy. |
Q51051139 | Extracellular Matrix Mediates BMP-2 in a Model of Temporomandibular Joint Osteoarthritis |
Q35741923 | Extracellular leucine-rich repeat proteins are required to organize the apical extracellular matrix and maintain epithelial junction integrity in C. elegans |
Q36381030 | Extracellular matrix assembly: a multiscale deconstruction |
Q34648597 | Fibromodulin binds collagen type I via Glu-353 and Lys-355 in leucine-rich repeat 11. |
Q36955365 | Fragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared with age-matched macroscopically normal and control tissues |
Q34137401 | Functional Coupling between the Extracellular Matrix and Nuclear Lamina by Wnt Signaling in Progeria |
Q51159226 | Genes encoding proteoglycans are associated with the risk of anterior cruciate ligament ruptures |
Q37136836 | Genetic evidence for the coordinated regulation of collagen fibrillogenesis in the cornea by decorin and biglycan |
Q33555398 | High expression of osteoglycin decreases gelatinase activity of murine hepatocarcinoma Hca-F cells |
Q39993448 | High expression of osteoglycin decreases the metastatic capability of mouse hepatocarcinoma Hca-F cells to lymph nodes |
Q35778467 | Higher Decorin Levels in Bone Marrow Plasma Are Associated with Superior Treatment Response to Novel Agent-Based Induction in Patients with Newly Diagnosed Myeloma - A Retrospective Study |
Q47124972 | Histopathologic and immunohistochemical features of capsular tissue around failed Ahmed glaucoma valves |
Q24657159 | Identification of LRRc17 as a negative regulator of receptor activator of NF-kappaB ligand (RANKL)-induced osteoclast differentiation |
Q46287333 | Identification, distribution and expression of osteoadherin during tooth formation |
Q35809362 | Impaired posterior frontal sutural fusion in the biglycan/decorin double deficient mice. |
Q49464004 | In vivo effect of opticin deficiency in cartilage in a surgically induced mouse model of osteoarthritis |
Q46678614 | Influence of aging on glycosaminoglycans and small leucine-rich proteoglycans production by skin fibroblasts |
Q36667920 | Influence of cyclic strain and decorin deficiency on 3D cellularized collagen matrices. |
Q30909828 | Initiation of the decorin glycosaminoglycan chain in the endoplasmic reticulum-Golgi intermediate compartment |
Q26822264 | Interstitial fluid and lymph formation and transport: physiological regulation and roles in inflammation and cancer |
Q36616140 | Keratocan is expressed by osteoblasts and can modulate osteogenic differentiation |
Q33819300 | Key roles for the small leucine-rich proteoglycans in renal and pulmonary pathophysiology |
Q27487873 | LRRCE: a leucine-rich repeat cysteine capping motif unique to the chordate lineage |
Q33378837 | Local and systemic gene expression responses of Atlantic salmon (Salmo salar L.) to infection with the salmon louse (Lepeophtheirus salmonis). |
Q40033256 | Lumican expression is positively correlated with the differentiation and negatively with the growth of human osteosarcoma cells |
Q39272702 | Lumican, an extracellular matrix proteoglycan, is a novel requisite for hepatic fibrosis |
Q35072127 | Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment. |
Q33526322 | Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells |
Q37174472 | Molecular structure of tail tendon fibers in TIEG1 knockout mice using synchrotron diffraction technology |
Q90682170 | Multifaceted Roles of Asporin in Cancer: Current Understanding |
Q42033519 | Mutation in cyclophilin B that causes hyperelastosis cutis in American Quarter Horse does not affect peptidylprolyl cis-trans isomerase activity but shows altered cyclophilin B-protein interactions and affects collagen folding |
Q46780310 | Nanomechanical phenotype of chondroadherin-null murine articular cartilage. |
Q30358171 | Novel mutations in the small leucine-rich repeat protein/proteoglycan (SLRP) genes in high myopia. |
Q37567146 | Novel small leucine-rich repeat protein podocan is a negative regulator of migration and proliferation of smooth muscle cells, modulates neointima formation, and is expressed in human atheroma |
Q36978276 | Osteoarthritis prevention through meniscal regeneration induced by intra-articular injection of meniscus stem cells |
Q33768466 | Osteoblastogenesis and tumor growth in myeloma |
Q53198376 | Osteopontin is highly expressed in severely dystrophic muscle and seems to play a role in muscle regeneration and fibrosis. |
Q47383965 | Overexpression of PLAP-1 in bone marrow stromal cells inhibits the rat critical-size skull defect repair |
Q33851493 | Pathophysiological Significance of Dermatan Sulfate Proteoglycans Revealed by Human Genetic Disorders. |
Q36085689 | Periostin regulates collagen fibrillogenesis and the biomechanical properties of connective tissues |
Q34454029 | Phenotypic characterization of epiphycan-deficient and epiphycan/biglycan double-deficient mice |
Q37340261 | Potential roles for the small leucine-rich proteoglycans biglycan and fibromodulin in ectopic ossification of tendon induced by exercise and in modulating rotarod performance. |
Q21710680 | Proteoglycan form and function: A comprehensive nomenclature of proteoglycans |
Q34398188 | Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine‐rich proteoglycans |
Q24337270 | Reduced type I collagen utilization: a pathogenic mechanism in COL5A1 haplo-insufficient Ehlers-Danlos syndrome |
Q28236087 | Regulation of PLAP-1 expression in periodontal ligament cells |
Q28582695 | Regulation of ureteric bud branching morphogenesis by sulfated proteoglycans in the developing kidney |
Q51116712 | Removal of dentin non-collagenous structures results in the unraveling of microfibril bundles in collagen type I. |
Q37545695 | Reprint of: Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells |
Q36473294 | Research perspectives: The 2013 AAOS/ORS research symposium on Bone Quality and Fracture Prevention. |
Q57027553 | Role of Extracellular Matrix in Development and Cancer Progression |
Q36732801 | Role of decorin in the antimyeloma effects of osteoblasts |
Q36877544 | Shared gene expression profiles in developing heart valves and osteoblast progenitor cells |
Q35566074 | Small leucine-rich proteoglycans exhibit unique spatiotemporal expression profiles during cardiac valve development |
Q37294495 | Small leucine-rich proteoglycans in atherosclerotic lesions: novel targets of chronic statin treatment? |
Q27652906 | Structural basis of sequence-specific collagen recognition by SPARC |
Q37939096 | Structure and function of the skeletal muscle extracellular matrix |
Q36995461 | System-level biomechanical approach for the evaluation of term and preterm pregnancy maintenance |
Q35769489 | The ECM proteoglycan decorin links desmoplasia and inflammation in chronic pancreatitis |
Q37986887 | The Ehlers-Danlos syndrome, a disorder with many faces |
Q92302379 | The Proteins of Keratoconus: a Literature Review Exploring Their Contribution to the Pathophysiology of the Disease |
Q28506468 | The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis |
Q26861290 | The biology of small leucine-rich proteoglycans in bone pathophysiology |
Q37101353 | The effect of the microscopic and nanoscale structure on bone fragility |
Q33299011 | The extracellular leucine-rich repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns |
Q35868405 | The interplay of extracellular matrix and microbiome in urothelial bladder cancer |
Q48219078 | The keratocan gene is expressed in both ocular and non-ocular tissues during early chick development |
Q39470009 | The mechanism of mimecan transcription induced by glucocorticoid in pituitary corticotroph cells |
Q38075193 | The regulatory roles of small leucine-rich proteoglycans in extracellular matrix assembly |
Q37228517 | The role of biglycan in the heart |
Q35905949 | The small leucine-rich proteoglycan, biglycan, is highly expressed in adipose tissue of Psammomys obesus and is associated with obesity and type 2 diabetes |
Q42532763 | Tissue-specific responses to loss of transglutaminase 2. |
Q52728763 | Transcription factor scleraxis vitally contributes to progenitor lineage direction in wound healing of adult tendon in mice. |
Q47824500 | Transient up-regulation of biglycan during skeletal muscle regeneration: delayed fiber growth along with decorin increase in biglycan-deficient mice. |
Q57334320 | Ullrich congenital muscular dystrophy: Connective tissue abnormalities in the skin support overlap with Ehlers-Danlos syndromes |
Q36430826 | Usurped SLRPs: novel arthritis biomarkers exposed by catabolism of small leucine-rich proteoglycans? |
Q34130533 | Uterine dysfunction in biglycan and decorin deficient mice leads to dystocia during parturition |
Q35937596 | Vascular extracellular matrix and aortic development. |
Q28070315 | Vascular proteomics in metabolic and cardiovascular diseases |
Q24670104 | WISP-1 is an osteoblastic regulator expressed during skeletal development and fracture repair |
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