Using PDE inhibitors to harness the benefits of calorie restriction: lessons from resveratrol

scientific article

Using PDE inhibitors to harness the benefits of calorie restriction: lessons from resveratrol is …
instance of (P31):
editorialQ871232
scholarly articleQ13442814

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P356DOI10.18632/AGING.100442
P932PMC publication ID3348474
P698PubMed publication ID22388573

P2093author name stringJay H Chung
P2860cites workThe AMP-activated protein kinase--fuel gauge of the mammalian cell?Q24315074
Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterasesQ24608197
SIRT1 activation by small molecules: kinetic and biophysical evidence for direct interaction of enzyme and activatorQ24626329
SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1Q24633063
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespanQ28203572
Mechanism of human SIRT1 activation by resveratrolQ28238262
Resveratrol is not a direct activator of SIRT1 enzyme activityQ28261917
Substrate-specific activation of sirtuins by resveratrolQ28305166
Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1alpha in skeletal muscleQ33627876
AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrolQ33688533
The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+).Q34242709
Life-long caloric restriction elicits pronounced protection of the aged myocardium: A role for AMPKQ34440321
Resveratrol stimulates AMP kinase activity in neuronsQ35758555
Resveratrol as an anticancer nutrient: molecular basis, open questions and promisesQ36206828
Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscleQ36739504
Roflumilast, a Novel Phosphodiesterase 4 Inhibitor, for COPD Patients with a History of Exacerbations.Q39020015
Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cellsQ39906875
Effects of flavonoids on cyclic AMP phosphodiesterase and lipid mobilization in rat adipocytes.Q54058827
P433issue3
P921main subjectcalorie restrictionQ1332886
P304page(s)144-145
P577publication date2012-03-01
P1433published inAgingQ2845875
P1476titleUsing PDE inhibitors to harness the benefits of calorie restriction: lessons from resveratrol
P478volume4

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cites work (P2860)
Q36260546Influence of non-steroidal anti-inflammatory drugs on Drosophila melanogaster longevity
Q37588979Novel insights of dietary polyphenols and obesity
Q28084341Quality control systems in cardiac aging
Q38043910Sirt1: def-eating senescence?
Q64272038Sirtuin signaling in cellular senescence and aging
Q28818352Synthesis and Assay of SIRT1-Activating Compounds
Q28395443Xenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agents