Analysis of the Cerebrospinal Fluid Proteome in Alzheimer's Disease

scientific article

Analysis of the Cerebrospinal Fluid Proteome in Alzheimer's Disease is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2016PLoSO..1150672K
P356DOI10.1371/JOURNAL.PONE.0150672
P932PMC publication ID4780771
P698PubMed publication ID26950848
P5875ResearchGate publication ID297594127

P50authorLars LannfeltQ5935335
Payam Emami KhoonsariQ57021586
Martin IngelssonQ87848339
Jonas BergquistQ40312473
Peter NilssonQ45896164
P2093author name stringKim Kultima
Lena Kilander
Anna Häggmark
Maria Mikus
Maria Lönnberg
Ganna Shevchenko
P2860cites workOpenMS - an open-source software framework for mass spectrometryQ21284208
Quantitative proteomic analysis of human substantia nigra in Alzheimer's disease, Huntington's disease and Multiple sclerosisQ24297593
Periodicity of leucine and tandem repetition of a 24-amino acid segment in the primary structure of leucine-rich alpha 2-glycoprotein of human serumQ24300009
Global prevalence of dementia: a Delphi consensus studyQ24603249
Tyrosine kinase signalling in breast cancer: modulation of tyrosine kinase signalling in human breast cancer through altered expression of signalling intermediatesQ24803027
Depletion of highly abundant proteins from human cerebrospinal fluid: a cautionary noteQ26782645
Clinical utility and analytical challenges in measurement of cerebrospinal fluid amyloid-β(1-42) and τ proteins as Alzheimer disease biomarkersQ27008249
Linear models and empirical bayes methods for assessing differential expression in microarray experimentsQ27860758
Fibulins: a versatile family of extracellular matrix proteinsQ28207887
PEAKS: powerful software for peptide de novo sequencing by tandem mass spectrometryQ28209613
The leucine-rich repeat as a protein recognition motifQ28212461
The classical complement cascade mediates CNS synapse eliminationQ28261273
Open mass spectrometry search algorithmQ28286936
Peptide fingerprinting of Alzheimer's disease in cerebrospinal fluid: identification and prospective evaluation of new synaptic biomarkersQ28477629
Open source libraries and frameworks for mass spectrometry based proteomics: a developer's perspectiveQ28660368
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantificationQ29547200
TANDEM: matching proteins with tandem mass spectraQ29615238
Andromeda: a peptide search engine integrated into the MaxQuant environmentQ29615816
Alzheimer's diseaseQ29616743
Microarray data normalization and transformationQ29617789
Computational methods for protein identification from mass spectrometry dataQ30000994
PEAKS DB: De Novo Sequencing Assisted Database Search for Sensitive and Accurate Peptide IdentificationQ30053602
Comparison of Mascot and X!Tandem performance for low and high accuracy mass spectrometry and the development of an adjusted Mascot thresholdQ30486531
An automated method for baseline correction, peak finding and peak grouping in chromatographic dataQ30624517
Comparative evaluation of preprocessing freeware on chromatography/mass spectrometry data for signature discoveryQ30838710
Evaluation of algorithms for protein identification from sequence databases using mass spectrometry dataQ30909732
A comparative evaluation of software for the analysis of liquid chromatography-tandem mass spectrometry data from isotope coded affinity tag experimentsQ30991942
Detection of biomarkers with a multiplex quantitative proteomic platform in cerebrospinal fluid of patients with neurodegenerative disorders.Q33254291
Normalization of oligonucleotide arrays based on the least-variant set of genesQ33322408
A consensus protocol for the standardization of cerebrospinal fluid collection and biobanking.Q33731693
Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formationQ33810171
Regulation of signaling by protein-tyrosine phosphatases: potential roles in the nervous systemQ33844146
Cerebrospinal fluid and plasma biomarkers in Alzheimer diseaseQ34098866
Tyrosine kinases and gastric cancerQ34103663
Leucine-rich alpha-2-glycoprotein-1 is upregulated in sera and tumors of ovarian cancer patientsQ34173955
Longitudinal cerebrospinal fluid biomarkers over four years in mild cognitive impairmentQ34220290
Protein markers for the differential diagnosis of vascular dementia and Alzheimer's diseaseQ34305901
An automated pipeline for high-throughput label-free quantitative proteomicsQ34326747
Longitudinal characterization of the brain proteomes for the tg2576 amyloid mouse model using shotgun based mass spectrometry.Q34438884
Alzheimer's disease and the aging brainQ34552927
Low levels of cerebrospinal fluid complement 3 and factor H predict faster cognitive decline in mild cognitive impairmentQ34630522
Depletion of multiple high-abundance proteins improves protein profiling capacities of human serum and plasma.Q50483624
Low cerebrospinal fluid concentration of mitochondrial DNA in preclinical Alzheimer disease.Q50489370
Reduced levels of amyloid-beta-binding proteins in cerebrospinal fluid from Alzheimer's disease patients.Q51817898
SPIDER: software for protein identification from sequence tags with de novo sequencing error.Q51966249
Probabilistic Consensus Scoring Improves Tandem Mass Spectrometry Peptide IdentificationQ57011814
Receptor tyrosine phosphatases in axon growth and guidanceQ74102347
Fibulin-3 is associated with tumour progression and a poor prognosis in nasopharyngeal carcinomas and inhibits cell migration and invasion via suppressed AKT activityQ85169334
Quantification of the brain proteome in Alzheimer's disease using multiplexed mass spectrometryQ35113785
Gastric cancer: prognostic and diagnostic advancesQ35677119
Analysis of a membrane-enriched proteome from postmortem human brain tissue in Alzheimer's disease.Q35917235
Protein tyrosine phosphatases and signallingQ36092317
The receptor protein tyrosine phosphatase (RPTP)beta/zeta is expressed in different subtypes of human breast cancerQ36156124
Current challenges in software solutions for mass spectrometry-based quantitative proteomicsQ36162392
Label-free quantitative LC-MS proteomics of Alzheimer's disease and normally aged human brainsQ36243522
Utilities for quantifying separation in PCA/PLS-DA scores plotsQ36501475
LRG-accelerated differentiation defines unique G-CSFR signaling pathways downstream of PU.1 and C/EBPepsilon that modulate neutrophil activationQ36648032
Decrease of fibulin-3 in hepatocellular carcinoma indicates poor prognosisQ37064102
Comparative LC-MS: a landscape of peaks and valleysQ37093728
Combining results of multiple search engines in proteomicsQ37160902
Cerebrospinal fluid biomarkers of neurodegeneration in chronic neurological diseasesQ37206262
Analysis of SNARE complex/synaptotagmin-1 interactions by one-dimensional NMR spectroscopyQ37265752
Development and evaluation of normalization methods for label-free relative quantification of endogenous peptides.Q37379620
Fibulins: multiple roles in matrix structures and tissue functions.Q37384312
Plasma biomarkers for mild cognitive impairment and Alzheimer's disease.Q37493113
Immune proteins in brain development and synaptic plasticity.Q37617631
Role of fibulin-3 in lung cancer: in vivo and in vitro analysesQ39076211
Intralipid decreases apolipoprotein M levels and insulin sensitivity in ratsQ39141955
A case study on the comparison of different software tools for automated quantification of peptidesQ39538264
Multidimensional plasma protein separation technique for identification of potential Alzheimer's disease plasma biomarkers: a pilot studyQ39641295
Neuronal pentraxin receptor in cerebrospinal fluid as a potential biomarker for neurodegenerative diseasesQ39860782
Combined rCBF and CSF biomarkers predict progression from mild cognitive impairment to Alzheimer's diseaseQ40190874
Protein tyrosine phosphatases in the developing nervous systemQ41750944
Altered expression of synaptic proteins occurs early during progression of Alzheimer's diseaseQ45172855
Antibody-based profiling of cerebrospinal fluid within multiple sclerosisQ45896107
Apolipoprotein M predicts pre-beta-HDL formation: studies in type 2 diabetic and nondiabetic subjects.Q46003867
Proteomic studies of potential cerebrospinal fluid protein markers for Alzheimer's diseaseQ48172055
Use of within-array replicate spots for assessing differential expression in microarray experimentsQ48502901
Age-related changes in cerebrospinal fluid protein concentrationsQ48702077
The macroeconomics of dementia--will the world economy get Alzheimer's disease?Q50119626
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that useslimmaQ112236343
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectcerebrospinal fluidQ54196
Alzheimer's diseaseQ11081
P304page(s)e0150672
P577publication date2016-03-07
P1433published inPLOS OneQ564954
P1476titleAnalysis of the Cerebrospinal Fluid Proteome in Alzheimer's Disease
P478volume11

Reverse relations

cites work (P2860)
Q90028613A High-throughput Bead-based Affinity Assay Enables Analysis of Genital Protein Signatures in Women At Risk of HIV Infection
Q42684122A novel quantification-driven proteomic strategy identifies an endogenous peptide of pleiotrophin as a new biomarker of Alzheimer's disease
Q92995041Abundant neuroprotective chaperone Lipocalin-type prostaglandin D synthase (L-PGDS) disassembles the Amyloid-β fibrils
Q42281478Age-related neurodegenerative disease associated pathways identified in retinal and vitreous proteome from human glaucoma eyes.
Q91763319Amyloid β chaperone - lipocalin-type prostaglandin D synthase acts as a peroxidase in the presence of heme
Q39178864CSF analysis for protein biomarker identification in patients with leptomeningeal metastases from CNS lymphoma
Q36357894Changes of Cerebrospinal Fluid Peptides due to Tauopathy.
Q89576000Discovery of the Consistently Well-Performed Analysis Chain for SWATH-MS Based Pharmacoproteomic Quantification
Q57469898Exome sequencing in an Italian family with Alzheimer's disease points to a role for seizure-related gene 6 (SEZ6) rare variant R615H
Q97535190Extracellular proteostasis prevents aggregation during pathogenic attack
Q37329676Functions of the Alzheimer's Disease Protease BACE1 at the Synapse in the Central Nervous System.
Q91583660Lipid-Binding Proteins in Brain Health and Disease
Q47417067Plasma Proteomic Profiles of Cerebrospinal Fluid-Defined Alzheimer's Disease Pathology in Older Adults
Q58779295Proteomic Approaches for the Discovery of Biofluid Biomarkers of Neurodegenerative Dementias
Q47763379Proteomic Biomarker Identification in Cerebrospinal Fluid for Leptomeningeal Metastases with Neurological Complications
Q47932570Proteomic studies of cerebrospinal fluid biomarkers of Alzheimer's disease: an update
Q56983020Proteomics of neurodegenerative diseases: analysis of human post-mortem brain
Q98613084Six-Gene Signature Associated with Immune Cells in the Progression of Atherosclerosis Discovered by Comprehensive Bioinformatics Analyses
Q90564396The Challenge to Search for New Nervous System Disease Biomarker Candidates: the Opportunity to Use the Proteogenomics Approach
Q39167734The potential impact of recent insights into proteomic changes associated with glaucoma

Search more.