Correction of the X-linked immunodeficiency phenotype by transgenic expression of human Bruton tyrosine kinase under the control of the class II major histocompatibility complex Ea locus control region

scientific article

Correction of the X-linked immunodeficiency phenotype by transgenic expression of human Bruton tyrosine kinase under the control of the class II major histocompatibility complex Ea locus control region is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1997PNAS...94..610D
P356DOI10.1073/PNAS.94.2.610
P932PMC publication ID19561
P698PubMed publication ID9012832
P5875ResearchGate publication ID24450592

P2093author name stringGrosveld F
Savelkoul HF
De Wit TP
Dingjan GM
Drabek D
Hendriks RW
Raguz S
P2860cites workBinding of Bruton's tyrosine kinase to Fyn, Lyn, or Hck through a Src homology 3 domain-mediated interactionQ24564184
Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagementQ28615625
B-cell antigen receptor stimulation activates the human Bruton's tyrosine kinase, which is deficient in X-linked agammaglobulinemiaQ28615845
BTKbase, mutation database for X-linked agammaglobulinemia (XLA).Q30192775
IL-5 receptor-mediated tyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton's tyrosine and Janus 2 kinasesQ30193880
Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemiaQ30195143
The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinasesQ34355151
Vertebrate non-receptor protein-tyrosine kinase familiesQ34425007
Far upstream regions of class II MHC Ea are necessary for position-independent, copy-dependent expression of Ea transgeneQ34981826
Bruton tyrosine kinase is tyrosine phosphorylated and activated in pre-B lymphocytes and receptor-ligated B cellsQ35864977
Inactivation of Btk by insertion of lacZ reveals defects in B cell development only past the pre-B cell stageQ35908626
Sequences and factors: a guide to MHC class-II transcriptionQ36135151
Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrowQ36230070
Unbalanced X chromosome mosaicism in B cells of mice with X-linked immunodeficiencyQ36348127
Development of B lymphocytes in mice heterozygous for the X-linked immunodeficiency (xid) mutation. xid inhibits development of all splenic and lymph node B cells at a stage subsequent to their initial formation in bone marrowQ36353541
The CBA/N mouse strain: an experimental model illustrating the influence of the X-chromosome on immunity.Q40113569
Molecular and cellular aspects of X-linked agammaglobulinemia.Q40373279
B-cell differentiation in the bone marrow and the periphery.Q40673776
Bruton's tyrosine kinase is a key regulator in B-cell developmentQ40694860
X-linked agammaglobulinemia: new approaches to old questions based on the identification of the defective gene.Q40694880
X-linked agammaglobulinemia (XLA): a genetic tyrosine kinase (Btk) diseaseQ41182308
Defective B cell development and function in Btk-deficient miceQ41306033
Association and activation of Btk and Tec tyrosine kinases by gp130, a signal transducer of the interleukin-6 family of cytokinesQ41378321
The Bruton's tyrosine kinase gene is expressed throughout B cell differentiation, from early precursor B cell stages preceding immunoglobulin gene rearrangement up to mature B cell stagesQ41510794
Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID miceQ41541610
B lymphocyte production in the bone marrow of mice with X-linked immunodeficiency (xid).Q44969200
Prolonged in vivo IL-4 treatment inhibits antigen-specific IgG1 and IgE formation.Q52057514
Aberrant B Cell Development and Immune Response in Mice with a Compromised BCR ComplexQ57198357
B-cell subpopulations identified by two-colour fluorescence analysisQ59095894
Expression of the gene defect in X-linked agammaglobulinemiaQ68802596
Demonstration of B-cell maturation in X-linked immunodeficient mice by simultaneous three-colour immunofluorescenceQ70303278
Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67Q72743242
Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genesQ72835320
P4510describes a project that usesImageQuantQ112270642
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectphenotypeQ104053
P304page(s)610-615
P577publication date1997-01-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleCorrection of the X-linked immunodeficiency phenotype by transgenic expression of human Bruton tyrosine kinase under the control of the class II major histocompatibility complex Ea locus control region
P478volume94

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cites work (P2860)
Q43826446A Btk transgene restores the antiviral TI-2 antibody responses of xid mice in a dose-dependent fashion
Q38161559Agammaglobulinemia: causative mutations and their implications for novel therapies
Q33747337B cell-specific lentiviral gene therapy leads to sustained B-cell functional recovery in a murine model of X-linked agammaglobulinemia
Q38581000BTK Signaling in B Cell Differentiation and Autoimmunity
Q45050515Bi-directional regulation between tyrosine kinase Etk/BMX and tumor suppressor p53 in response to DNA damage
Q36720312Btk dosage determines sensitivity to B cell antigen receptor cross-linking
Q40005186Development of an enhanced B-specific lentiviral vector expressing BTK: a tool for gene therapy of XLA.
Q38988830Enhanced Bruton's Tyrosine Kinase Activity in Peripheral Blood B Lymphocytes From Patients With Autoimmune Disease
Q77174555Genetic basis of abnormal B cell development
Q73149913Modulation by Anapsos (Polypodium leucotomos extract) of the antibody responses against the nematode parasite Trichinella spiralis
Q45862082Murine MHC class II locus control region drives expression of human beta-glucocerebrosidase in antigen presenting cells of transgenic mice
Q33889470Severe B cell deficiency and disrupted splenic architecture in transgenic mice expressing the E41K mutated form of Bruton's tyrosine kinase
Q38198490Targeting Bruton's tyrosine kinase in B cell malignancies
Q73814849The X-linked immunodeficiency defect in the mouse is corrected by expression of human Bruton's tyrosine kinase from a yeast artificial chromosome transgene
Q53144072The effect of glycosylation of antigens on the antibody responses against Echinostoma caproni (Trematoda: Echinostomatidae).
Q34099457X-linked agammaglobulinemia

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