Development of an enhanced B-specific lentiviral vector expressing BTK: a tool for gene therapy of XLA.

scientific article

Development of an enhanced B-specific lentiviral vector expressing BTK: a tool for gene therapy of XLA. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1043980333
P356DOI10.1038/GT.2008.17
P698PubMed publication ID18323795
P5875ResearchGate publication ID5528141

P50authorThomas MoreauQ80282050
Jacques A NunesQ58937410
P2093author name stringC Tonnelle
C Chabannon
B Calmels
F Bardin
V Barlogis
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Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemiaQ30195143
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Expression of the (recombinant) endogenous immunoglobulin heavy-chain locus requires the intronic matrix attachment regionsQ38502702
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Cell-specific and efficient expression in mouse and human B cells by a novel hybrid immunoglobulin promoter in a lentiviral vector.Q40081805
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B-cell-specific transgene expression using a self-inactivating retroviral vector with human CD19 promoter and viral post-transcriptional regulatory elementQ44296349
Sustained correction of B-cell development and function in a murine model of X-linked agammaglobulinemia (XLA) using retroviral-mediated gene transferQ45875318
Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vectorQ45880148
A phase I/II clinical trial of beta-globin gene therapy for beta-thalassemiaQ45889126
A developmental-specific factor binds to suppressor sites flanking the immunoglobulin heavy-chain enhancer.Q52245349
X-Linked AgammaglobulinemiaQ62111760
P433issue12
P921main subjectgene therapyQ213901
P304page(s)942-952
P577publication date2008-03-06
P1433published inGene TherapyQ15763095
P1476titleDevelopment of an enhanced B-specific lentiviral vector expressing BTK: a tool for gene therapy of XLA
P478volume15

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cites work (P2860)
Q26742031Advances of gene therapy for primary immunodeficiencies
Q38161559Agammaglobulinemia: causative mutations and their implications for novel therapies
Q45870581Biology and novel treatment options for XLA, the most common monogenetic immunodeficiency in man.
Q45861548Correction of B-cell development in Btk-deficient mice using lentiviral vectors with codon-optimized human BTK.
Q30498317Development of B-lineage predominant lentiviral vectors for use in genetic therapies for B cell disorders
Q33844310Engineering humanized mice for improved hematopoietic reconstitution
Q38742256Expression of Tim-1 in primary CNS lymphoma
Q39033552Gene delivery in malignant B cells using the combination of lentiviruses conjugated to anti-transferrin receptor antibodies and an immunoglobulin promoter
Q34401676Gene transfer into hematopoietic stem cells as treatment for primary immunodeficiency diseases