| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Jouni Väliaho | Q117226556 |
| Mauno Vihinen | Q38591073 | ||
| Jessica M Lindvall | Q42417427 | ||
| Beston F Nore | Q55117912 | ||
| Smith Cie | Q58473540 | ||
| Juhana E. Heinonen | Q113133424 | ||
| Anna Berglöf | Q117226554 | ||
| P2093 | author name string | K Emelie M Blomberg | |
| Leonardo Vargas | |||
| Abdalla J Mohamed | |||
| P2860 | cites work | The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools | Q24248165 |
| BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement | Q24316165 | ||
| Regulation of nuclear localization and transcriptional activity of TFII-I by Bruton's tyrosine kinase | Q24554472 | ||
| Vav3 modulates B cell receptor responses by regulating phosphoinositide 3-kinase activation | Q24675128 | ||
| Structure of the PH domain from Bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate | Q27617853 | ||
| Solution structure of the SH3 domain from Bruton's tyrosine kinase | Q27748889 | ||
| Asymmetry in the assembly of the RNAi enzyme complex | Q27860763 | ||
| Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells | Q27860926 | ||
| Functional siRNAs and miRNAs Exhibit Strand Bias | Q27861038 | ||
| Engagement of the human pre-B cell receptor generates a lipid raft-dependent calcium signaling complex | Q28138324 | ||
| Phosphatidylinositol 3-kinase-dependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cells | Q28140934 | ||
| Functional interaction of caveolin-1 with Bruton's tyrosine kinase and Bmx | Q28212744 | ||
| A duplicated gene in the breakpoint regions of the 7q11.23 Williams-Beuren syndrome deletion encodes the initiator binding protein TFII-I and BAP-135, a phosphorylation target of BTK | Q28262012 | ||
| Regulation of Btk function by a major autophosphorylation site within the SH3 domain | Q28278818 | ||
| Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios | Q29616015 | ||
| Nucleocytoplasmic shuttling of Bruton's tyrosine kinase | Q30168721 | ||
| BTKbase, mutation database for X-linked agammaglobulinemia (XLA) | Q30176696 | ||
| Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia | Q30195143 | ||
| Effects of SH2 and SH3 deletions on the functional activities of wild-type and transforming variants of c-Src | Q30195430 | ||
| Genetic studies of the Lac repressor. XV: 4000 single amino acid substitutions and analysis of the resulting phenotypes on the basis of the protein structure | Q30425060 | ||
| The Drosophila Bruton's tyrosine kinase (Btk) homolog is required for adult survival and male genital formation | Q33652475 | ||
| Genetic analysis of B cell antigen receptor signaling | Q33652515 | ||
| Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-cell receptor activation | Q33888592 | ||
| The cellular phenotype conditions Btk for cell survival or apoptosis signaling. | Q34159340 | ||
| The Tec family of cytoplasmic tyrosine kinases: mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species | Q34243592 | ||
| The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases | Q34355151 | ||
| Mutations in btk in patients with presumed X-linked agammaglobulinemia | Q34385386 | ||
| Haemophilia B (sixth edition): a database of point mutations and short additions and deletions | Q34587135 | ||
| Haemophilia B: database of point mutations and short additions and deletions--eighth edition | Q34646217 | ||
| B cell antigen receptor signaling: roles in cell development and disease. | Q34662623 | ||
| The role of Tec family kinases in T cell development and function | Q35076690 | ||
| Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk. | Q36368328 | ||
| Bruton's tyrosine kinase links the B cell receptor to nuclear factor kappaB activation | Q36368467 | ||
| Bruton's tyrosine kinase is required for activation of IkappaB kinase and nuclear factor kappaB in response to B cell receptor engagement | Q36368492 | ||
| Bruton's tyrosine kinase is required for lipopolysaccharide-induced tumor necrosis factor alpha production | Q36370908 | ||
| Regulation of Btk by Src family tyrosine kinases | Q40019232 | ||
| BTKbase: a database of XLA-causing mutations. International Study Group. | Q40422765 | ||
| Phosphatidylinositol-3,4,5-trisphosphate (PtdIns-3,4,5-P3)/Tec kinase-dependent calcium signaling pathway: a target for SHIP-mediated inhibitory signals | Q41037034 | ||
| Defective B cell development and function in Btk-deficient mice | Q41306033 | ||
| A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2. | Q41855372 | ||
| Genetic studies of the lac repressor. XIV. Analysis of 4000 altered Escherichia coli lac repressors reveals essential and non-essential residues, as well as "spacers" which do not require a specific sequence. | Q46020329 | ||
| Systematic mutation of bacteriophage T4 lysozyme | Q50183536 | ||
| Clinical, immunological, and molecular analysis in a large cohort of patients with X-linked agammaglobulinemia: an Italian multicenter study. | Q51704872 | ||
| Direct evidence that oncogenic tyrosine kinases and cyclic AMP-dependent protein kinase have homologous ATP-binding sites. | Q53551132 | ||
| BTKbase, mutation database for X-linked agammaglobulinemia (XLA) | Q57269822 | ||
| Mutation screening of the BTK gene in 56 families with X-linked agammaglobulinemia (XLA): 47 unique mutations without correlation to clinical course | Q58482629 | ||
| BTKbase: XLA-mutation registry | Q58533464 | ||
| P921 | main subject | cell biology | Q7141 |
| P304 | page(s) | 200-215 | |
| P577 | publication date | 2005-02-01 | |
| P1433 | published in | Immunological Reviews | Q15724582 |
| P1476 | title | Bruton's tyrosine kinase: cell biology, sequence conservation, mutation spectrum, siRNA modifications, and expression profiling | |
| P478 | volume | 203 |
| Q38944958 | A general approach for the development of fluorogenic probes suitable for no-wash imaging of kinases in live cells |
| Q34097544 | A novel immunodeficiency associated with hypomorphic RAG1 mutations and CMV infection |
| Q30008753 | ANKRD54 preferentially selects Bruton's Tyrosine Kinase (BTK) from a Human Src-Homology 3 (SH3) domain library |
| Q33700656 | Adults with X-linked agammaglobulinemia: impact of disease on daily lives, quality of life, educational and socioeconomic status, knowledge of inheritance, and reproductive attitudes |
| Q38161559 | Agammaglobulinemia: causative mutations and their implications for novel therapies |
| Q36548443 | Analysis of the Effects of the Bruton's tyrosine kinase (Btk) Inhibitor Ibrutinib on Monocyte Fcγ Receptor (FcγR) Function |
| Q30009224 | Autoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate |
| Q34514813 | B-cell targeting in rheumatoid arthritis and other autoimmune diseases |
| Q40488148 | BTK mutations selectively regulate BTK expression and upregulate monocyte XBP1 mRNA in XLA patients |
| Q41344360 | BTK suppresses myeloma cellular senescence through activating AKT/P27/Rb signaling |
| Q43164233 | BTK: sensing pathogenic nucleic acids |
| Q36592292 | BTKbase: the mutation database for X-linked agammaglobulinemia. |
| Q35181271 | Bruton's TK inhibitors: structural insights and evolution of clinical candidates |
| Q46217363 | Bruton's Tyrosine Kinase Small Molecule Inhibitors Induce a Distinct Pancreatic Toxicity in Rats. |
| Q24321955 | Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain |
| Q37787243 | Bruton's tyrosine kinase as a molecular target in treatment of leukemias and lymphomas as well as inflammatory disorders and autoimmunity |
| Q35889249 | Bruton's tyrosine kinase phosphorylates Toll-like receptor 3 to initiate antiviral response |
| Q38163953 | Bruton's tyrosine kinase--an integral protein of B cell development that also has an essential role in the innate immune system |
| Q41524241 | Bruton's tyrosine kinase: from X-linked agammaglobulinemia toward targeted therapy for B-cell malignancies |
| Q33794555 | Btk regulates B cell receptor-mediated antigen processing and presentation by controlling actin cytoskeleton dynamics in B cells |
| Q37239601 | Cellular membranes and lipid-binding domains as attractive targets for drug development |
| Q30372772 | Characterization of all possible single-nucleotide change caused amino acid substitutions in the kinase domain of Bruton tyrosine kinase. |
| Q81737051 | Clinical and molecular analysis of 49 patients with X-linked agammaglobulinemia from a single center in Argentina |
| Q33745733 | Clinical and mutational features of Vietnamese children with X-linked agammaglobulinemia |
| Q37176048 | Clinical characteristics and genetic profiles of 174 patients with X-linked agammaglobulinemia: Report from Shanghai, China (2000-2015). |
| Q84880299 | Clinical characteristics and genotype-phenotype correlation in 62 patients with X-linked agammaglobulinemia |
| Q51279362 | Clinical features and mutation analysis of X-linked agammaglobulinemia in 20 Chinese patients. |
| Q37094690 | Clinical potential of targeting Bruton's tyrosine kinase |
| Q39972146 | Cohort of Iranian Patients with Congenital Agammaglobulinemia: Mutation Analysis and Novel Gene Defects |
| Q39788223 | Compensatory role of inducible annexin A2 for impaired biliary epithelial anion-exchange activity of inflammatory cholangiopathy. |
| Q50776660 | Contiguous X-chromosome deletion syndrome encompassing the BTK, TIMM8A, TAF7L, and DRP2 genes. |
| Q45861548 | Correction of B-cell development in Btk-deficient mice using lentiviral vectors with codon-optimized human BTK. |
| Q34131208 | Critical roles of the WASP N-terminal domain and Btk in LPS-induced inflammatory response in macrophages |
| Q57783617 | Defective Toll-like receptor 9-mediated cytokine production in B cells from Bruton's tyrosine kinase-deficient mice |
| Q47333784 | Delayed diagnosis in X-linked agammaglobulinemia and its relationship to the occurrence of mutations in BTK non-kinase domains. |
| Q40005186 | Development of an enhanced B-specific lentiviral vector expressing BTK: a tool for gene therapy of XLA. |
| Q38188862 | Emerging immunotherapies for rheumatoid arthritis. |
| Q24651311 | Epidemiology, etiology, pathogenesis, and diagnosis of recurrent bacterial meningitis |
| Q34402076 | Essential roles for the Tec family kinases Tec and Btk in M-CSF receptor signaling pathways that regulate macrophage survival |
| Q81362601 | Expression of Fc gamma and complement receptors in monocytes of X-linked agammaglobulinaemia and common variable immunodeficiency patients |
| Q38817591 | From identification of the BTK kinase to effective management of leukemia. |
| Q39911338 | Global target profile of the kinase inhibitor bosutinib in primary chronic myeloid leukemia cells |
| Q37486515 | Hyperactivated B cells in human inflammatory bowel disease |
| Q30303054 | Ibrutinib interferes with the cell-mediated anti-tumor activities of therapeutic CD20 antibodies: implications for combination therapy |
| Q40323773 | Identification of Bruton tyrosine kinase mutations in 12 Chinese patients with X-linked agammaglobulinaemia by long PCR-direct sequencing |
| Q36605099 | Immunodeficiency mutation databases (IDbases). |
| Q43646833 | In-silico characterization of the effects of phosphorylated tyrosines 86 and 106 on structure and binding of MAL: insight into hyperinflammatory response to infection by the human malaria parasites. |
| Q47594568 | Increased intracellular Ca2+ concentrations prevent membrane localization of PH domains through the formation of Ca2+-phosphoinositides. |
| Q47129847 | Inherent X-Linked Genetic Variability and Cellular Mosaicism Unique to Females Contribute to Sex-Related Differences in the Innate Immune Response |
| Q34722000 | Inhibitors of BTK and ITK: state of the new drugs for cancer, autoimmunity and inflammatory diseases. |
| Q27666787 | Insights into the conformational flexibility of Bruton's tyrosine kinase from multiple ligand complex structures |
| Q57965147 | Loss-of-function mutations within the IL-2 inducible kinase ITK in patients with EBV-associated lymphoproliferative diseases |
| Q29614848 | Membrane recognition by phospholipid-binding domains |
| Q41200923 | Membranous glomerulopathy in an adult patient with X-linked agammaglobulinemia receiving intravenous gammaglobulin |
| Q36745060 | Molecular mechanism of membrane targeting by the GRP1 PH domain |
| Q40350619 | Mutational analysis of the SH2-kinase linker region of Bruton's tyrosine kinase defines alternative modes of regulation for cytoplasmic tyrosine kinase families |
| Q90048040 | Nanoparticle-Mediated Therapeutic Application for Modulation of Lysosomal Ion Channels and Functions |
| Q36544048 | New insights into the cell biology of the marginal zone of the spleen |
| Q38072417 | Novel small molecule therapeutics in rheumatoid arthritis |
| Q37375071 | Phylogeny of Tec family kinases identification of a premetazoan origin of Btk, Bmx, Itk, Tec, Txk, and the Btk regulator SH3BP5. |
| Q36798706 | Physical and functional characterization of the genetic locus of IBtk, an inhibitor of Bruton's tyrosine kinase: evidence for three protein isoforms of IBtk |
| Q36096748 | RNA interference in biology and disease |
| Q40286524 | Regulation of Bruton tyrosine kinase by the peptidylprolyl isomerase Pin1. |
| Q30010124 | Regulation of nucleocytoplasmic shuttling of Bruton's tyrosine kinase (Btk) through a novel SH3-dependent interaction with ankyrin repeat domain 54 (ANKRD54). |
| Q35612194 | Role of Bruton's tyrosine kinase inhibitors in HIV-1-infected cells |
| Q37452843 | Serosal inflammation (pleural and pericardial effusions) related to tyrosine kinase inhibitors |
| Q24548765 | Skewed Th1 responses caused by excessive expression of Txk, a member of the Tec family of tyrosine kinases, in patients with Behcet's disease |
| Q42791258 | Specific Btk inhibition suppresses B cell– and myeloid cell–mediated arthritis |
| Q35033817 | Splice-correction strategies for treatment of X-linked agammaglobulinemia. |
| Q64095477 | Structural mechanism for Bruton's tyrosine kinase activation at the cell membrane |
| Q38765458 | Substitution scanning identifies a novel, catalytically active ibrutinib-resistant BTK cysteine 481 to threonine (C481T) variant. |
| Q37868757 | TEC family kinases in health and disease--loss-of-function of BTK and ITK and the gain-of-function fusions ITK-SYK and BTK-SYK. |
| Q37216903 | TRPMLs: in sickness and in health |
| Q28087772 | Targets for Ibrutinib Beyond B Cell Malignancies |
| Q37997073 | Tec family kinases in inflammation and disease |
| Q37848482 | Tec family kinases: regulation of FcεRI-mediated mast-cell activation |
| Q36877295 | Tec kinases, actin, and cell adhesion |
| Q34204293 | The calcium channel mucolipin-3 is a novel regulator of trafficking along the endosomal pathway |
| Q37997076 | The role of Tec family kinases in the regulation of T-helper-cell differentiation |
| Q37158872 | The tyrosine kinase network regulating mast cell activation |
| Q36190423 | Toll-like receptor 4-, 7-, and 8-activated myeloid cells from patients with X-linked agammaglobulinemia produce enhanced inflammatory cytokines |
| Q36190430 | Toll-like receptor function in primary B cell defects |
| Q33446486 | Transcriptional signatures of Itk-deficient CD3+, CD4+ and CD8+ T-cells |
| Q37247193 | Translational mini-review series on the immunogenetics of gut disease: immunogenetics of coeliac disease. |
| Q36308865 | Variable phenotypic expression of mutations in genes of the immune system |
| Q80153210 | X-linked agammaglobulinemia diagnosed in adulthood: a case report |
Search more.