| scholarly article | Q13442814 |
| P50 | author | John C. Byrd | Q66429603 |
| P2093 | author name string | Li Ren | |
| Huiqing Fang | |||
| Susheela Tridandapani | |||
| Xiaokui Mo | |||
| Jonathan P Butchar | |||
| Andrew Stiff | |||
| William E Carson | |||
| Payal Mehta | |||
| Amanda Campbell | |||
| Shalini Gautam | |||
| Kavin Fatehchand | |||
| Saranya Elavazhagan | |||
| Brenda F Reader | |||
| P2860 | cites work | The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells | Q21195261 |
| The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy | Q24633214 | ||
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| RN486, a selective Bruton's tyrosine kinase inhibitor, abrogates immune hypersensitivity responses and arthritis in rodents | Q28567706 | ||
| Immunoglobulin G-mediated phagocytosis activates a calcium-independent, phosphatidylethanolamine-specific phospholipase | Q28610358 | ||
| IgG Fc receptors | Q29615378 | ||
| The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C | Q30047790 | ||
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| LyGDI, a novel SHIP-interacting protein, is a negative regulator of FcγR-mediated phagocytosis | Q33939284 | ||
| Discovery of selective irreversible inhibitors for Bruton's tyrosine kinase | Q34001339 | ||
| Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765. | Q34026194 | ||
| Safety and activity of ibrutinib plus rituximab for patients with high-risk chronic lymphocytic leukaemia: a single-arm, phase 2 study | Q34240404 | ||
| The Tec family of cytoplasmic tyrosine kinases: mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species | Q34243592 | ||
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| Safety and activity of BTK inhibitor ibrutinib combined with ofatumumab in chronic lymphocytic leukemia: a phase 1b/2 study | Q35953518 | ||
| Fc-receptor-mediated phagocytosis occurs in macrophages without an increase in average [Ca++]i. | Q36214938 | ||
| Fc receptor-mediated phagocytosis occurs in macrophages at exceedingly low cytosolic Ca2+ levels | Q36218675 | ||
| X-linked B-lymphocyte immune defect in CBA/N mice. II. Studies of the mechanisms underlying the immune defect | Q36358381 | ||
| Bruton's tyrosine kinase is required for lipopolysaccharide-induced tumor necrosis factor alpha production | Q36370908 | ||
| Colocalization of the IL-12 receptor and FcgammaRIIIa to natural killer cell lipid rafts leads to activation of ERK and enhanced production of interferon-gamma | Q36528782 | ||
| Toll-like receptor 2 ligands regulate monocyte Fcγ receptor expression and function | Q36796964 | ||
| The Bruton tyrosine kinase (BTK) inhibitor PCI-32765 synergistically increases proteasome inhibitor activity in diffuse large-B cell lymphoma (DLBCL) and mantle cell lymphoma (MCL) cells sensitive or resistant to bortezomib | Q37084564 | ||
| Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes | Q37226729 | ||
| B cell receptor and BAFF receptor signaling regulation of B cell homeostasis | Q37591049 | ||
| Fc receptor-targeted therapies for the treatment of inflammation, cancer and beyond | Q37998314 | ||
| Vav regulates activation of Rac but not Cdc42 during FcgammaR-mediated phagocytosis | Q39540613 | ||
| Dual functions of Bruton's tyrosine kinase and Tec kinase during Fcgamma receptor-induced signaling and phagocytosis. | Q39970323 | ||
| The activation of natural killer cell effector functions by cetuximab-coated, epidermal growth factor receptor positive tumor cells is enhanced by cytokines | Q40061963 | ||
| Signaling by Toll-like receptors 8 and 9 requires Bruton's tyrosine kinase | Q40068866 | ||
| FcgammaR-induced production of superoxide and inflammatory cytokines is differentially regulated by SHIP through its influence on PI3K and/or Ras/Erk pathways | Q40303488 | ||
| Bruton's tyrosine kinase is involved in p65-mediated transactivation and phosphorylation of p65 on serine 536 during NFkappaB activation by lipopolysaccharide | Q40431320 | ||
| The serine/threonine kinase Akt Promotes Fc gamma receptor-mediated phagocytosis in murine macrophages through the activation of p70S6 kinase | Q40504128 | ||
| Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice | Q41541610 | ||
| Protein tyrosine phosphorylation induced via the IgG receptors Fc gamma Ri and Fc gamma RII in the human monocytic cell line THP-1 | Q41605709 | ||
| Ibrutinib antagonizes rituximab-dependent NK cell-mediated cytotoxicity | Q42401591 | ||
| Ibrutinib impairs the phagocytosis of rituximab-coated leukemic cells from chronic lymphocytic leukemia patients by human macrophages. | Q42660684 | ||
| Specific Btk inhibition suppresses B cell– and myeloid cell–mediated arthritis | Q42791258 | ||
| Delayed clearance of filarial infection and enhanced Th1 immunity due to modulation of macrophage APC functions in xid mice. | Q43589679 | ||
| The inositol 3-phosphatase PTEN negatively regulates Fc gamma receptor signaling, but supports Toll-like receptor 4 signaling in murine peritoneal macrophages | Q44832270 | ||
| Pleiotropic consequences of Bruton tyrosine kinase deficiency in myeloid lineages lead to poor inflammatory responses | Q44875085 | ||
| Btk function in B cell development and response. | Q45939727 | ||
| Src Homology 2 Domain-Containing Inositol Polyphosphate Phosphatase Regulates NF- B-Mediated Gene Transcription by Phagocytic Fc Rs in Human Myeloid Cells | Q56600616 | ||
| Studies of peritoneal macrophage function in mice with systemic lupus erythematosus: Depressed phagocytosis of opsonized sheep erythrocytes in vitro | Q60300196 | ||
| Bruton's tyrosine kinase is not essential for LPS-induced activation of human monocytes | Q62640362 | ||
| Cross-linking of both Fc gamma RI and Fc gamma RII induces secretion of tumor necrosis factor by human monocytes, requiring high affinity Fc-Fc gamma R interactions. Functional activation of Fc gamma RII by treatment with proteases or neuraminidase | Q68410317 | ||
| Cross-linking Fc receptors on monocytes triggers IL-6 production. Role in anti-CD3-induced T cell activation | Q68425185 | ||
| Protein kinase C activation precedes arachidonic acid release during IgG-mediated phagocytosis | Q71586943 | ||
| Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genes | Q72835320 | ||
| Aggregated immunoglobulin protects immune T cells from suppression: dependence on isotype, Fc portion, and macrophage FcgammaR | Q74297348 | ||
| Defective degranulation and calcium mobilization of bone-marrow derived mast cells from Xid and Btk-deficient mice | Q77741607 | ||
| Macrophage effector functions controlled by Bruton's tyrosine kinase are more crucial than the cytokine balance of T cell responses for microfilarial clearance | Q77743735 | ||
| Bruton's tyrosine kinase deficiency in macrophages inhibits nitric oxide generation leading to enhancement of IL-12 induction | Q78102908 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | ibrutinib | Q5984881 |
| P304 | page(s) | 3043-3052 | |
| P577 | publication date | 2015-12-01 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Analysis of the Effects of the Bruton's tyrosine kinase (Btk) Inhibitor Ibrutinib on Monocyte Fcγ Receptor (FcγR) Function | |
| P478 | volume | 291 |
| Q50066279 | Bruton's Tyrosine Kinase, a Component of B Cell Signaling Pathways, Has Multiple Roles in the Pathogenesis of Lupus |
| Q46011813 | Chronic lymphocytic leukemia cells are active participants in microenvironmental cross-talk. |
| Q33774517 | Cirmtuzumab inhibits Wnt5a-induced Rac1 activation in chronic lymphocytic leukemia treated with ibrutinib |
| Q55001348 | Cirmtuzumab inhibits ibrutinib-resistant, Wnt5a-induced Rac1 activation and proliferation in mantle cell lymphoma. |
| Q47202386 | Fc gamma receptors are expressed in the developing rat brain and activate downstream signaling molecules upon cross-linking with immune complex |
| Q55690832 | Ibrutinib withdrawal symptoms in patients with Waldenström macroglobulinemia. |
| Q54979047 | Immunological changes with kinase inhibitor therapy for chronic lymphocytic leukemia. |
| Q64117432 | Monocyte-to-macrophage switch reversibly impaired by Ibrutinib |
| Q90341760 | Murine macrophage TLR2-FcγR synergy via FcγR licensing of IL-6 cytokine mRNA ribosome binding and translation |
| Q47445525 | Pharmacodynamics and proteomic analysis of acalabrutinib therapy: similarity of on-target effects to ibrutinib and rationale for combination therapy |
| Q93017736 | Role of Bruton's Tyrosine Kinase in Stage III Colorectal Cancer |
| Q36350848 | The lack of BTK does not impair monocytes and polymorphonuclear cells functions in X-linked agammaglobulinemia under treatment with intravenous immunoglobulin replacement |
| Q89734941 | Using Informatics Tools to Identify Opportunities for Precision Medicine in Diffuse Large B-cell Lymphoma |
| Q98458131 | ZYBT1, a potent, irreversible Bruton's Tyrosine Kinase (BTK) inhibitor that inhibits the C481S BTK with profound efficacy against arthritis and cancer |
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