The Type III Secretion Translocation Pore Senses Host Cell Contact.

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The Type III Secretion Translocation Pore Senses Host Cell Contact. is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PPAT.1005530
P932PMC publication ID4811590
P698PubMed publication ID27022930

P50authorArne RietschQ38362093
P2093author name stringErin I Armentrout
P2860cites workBacterial type III secretion systems: specialized nanomachines for protein delivery into target cellsQ27028058
The type III secretion system needle tip complex mediates host cell sensing and translocon insertion.Q53575352
Synergistic Pore Formation by Type III Toxin Translocators ofPseudomonas aeruginosa†Q57365041
Enhanced secretion through the Shigella flexneri Mxi-Spa translocon leads to assembly of extracellular proteins into macromolecular structuresQ64360979
Characterization of the interaction of IpaB and IpaD, proteins required for entry of Shigella flexneri into epithelial cells, with a lipid membraneQ74261400
Characterization of translocation pores inserted into plasma membranes by type III-secreted Esp proteins of enteropathogenic Escherichia coliQ74581423
The needle component of the type III secreton of Shigella regulates the activity of the secretion apparatusQ81355843
The IpaC carboxyterminal effector domain mediates Src-dependent actin polymerization during Shigella invasion of epithelial cellsQ27318175
Structure of theYersinia pestistip protein LcrV refined to 1.65 Å resolutionQ27678232
Membrane and Chaperone Recognition by the Major Translocator Protein PopB of the Type III Secretion System of Pseudomonas aeruginosaQ27680731
Protein structure prediction on the Web: a case study using the Phyre serverQ27860664
Modified needle-tip PcrV proteins reveal distinct phenotypes relevant to the control of type III secretion and intoxication by Pseudomonas aeruginosaQ28492629
Polarisation of type III translocation by Pseudomonas aeruginosa requires PcrG, PcrV and PopNQ28492777
Protein binding between PcrG-PcrV and PcrH-PopB/PopD encoded by the pcrGVH-popBD operon of the Pseudomonas aeruginosa type III secretion systemQ28492902
ExsE, a secreted regulator of type III secretion genes in Pseudomonas aeruginosaQ28492983
Regulatory role of PopN and its interacting partners in type III secretion of Pseudomonas aeruginosaQ28493109
pH Sensing by Intracellular Salmonella Induces Effector TranslocationQ29037234
ExoS controls the cell contact-mediated switch to effector secretion in Pseudomonas aeruginosaQ30481673
Salmonella enterica serovar typhimurium pathogenicity island 1-encoded type III secretion system translocases mediate intimate attachment to nonphagocytic cellsQ30488707
Control of type III secretion activity and substrate specificity by the cytoplasmic regulator PcrG.Q33627041
The tripartite type III secreton of Shigella flexneri inserts IpaB and IpaC into host membranesQ33878820
A program of Yersinia enterocolitica type III secretion reactions is activated by specific signalsQ33996710
The type III secretion system tip complex and translocon.Q34011259
Control of effector export by the Pseudomonas aeruginosa type III secretion proteins PcrG and PcrV.Q35071514
A C-terminal region of Yersinia pestis YscD binds the outer membrane secretin YscCQ35095963
Homologs of the Shigella IpaB and IpaC invasins are required for Salmonella typhimurium entry into cultured epithelial cellsQ35589961
A translocator-specific export signal establishes the translocator-effector secretion hierarchy that is important for type III secretion system functionQ36472851
Piecing together the type III injectisome of bacterial pathogensQ37079418
Metabolic regulation of type III secretion gene expression in Pseudomonas aeruginosa.Q37124570
Membrane targeting and pore formation by the type III secretion system transloconQ37823656
Type III secretion systems: the bacterial flagellum and the injectisomeQ38586932
The extreme C terminus of Shigella flexneri IpaB is required for regulation of type III secretion, needle tip composition, and binding.Q39896038
Oligomerization of type III secretion proteins PopB and PopD precedes pore formation in PseudomonasQ39927824
IpaD of Shigella flexneri is independently required for regulation of Ipa protein secretion and efficient insertion of IpaB and IpaC into host membranes.Q40454544
Genetic analysis of the formation of the Ysc-Yop translocation pore in macrophages by Yersinia enterocolitica: role of LcrV, YscF and YopN.Q40622724
Target cell contact triggers expression and polarized transfer of Yersinia YopE cytotoxin into mammalian cells.Q40790987
Pore-forming activity of type III system-secreted proteins leads to oncosis of Pseudomonas aeruginosa-infected macrophagesQ40813368
The YopD translocator of Yersinia pseudotuberculosis is a multifunctional protein comprised of discrete domains.Q40909327
The V antigen of Pseudomonas aeruginosa is required for assembly of the functional PopB/PopD translocation pore in host cell membranesQ41195095
YopD self-assembly and binding to LcrV facilitate type III secretion activity by Yersinia pseudotuberculosisQ41433693
Function and molecular architecture of the Yersinia injectisome tip complexQ41447558
The V-antigen of Yersinia forms a distinct structure at the tip of injectisome needlesQ41456399
The Yersinia pestis type III secretion needle plays a role in the regulation of Yop secretionQ41457055
Protective anti-V antibodies inhibit Pseudomonas and Yersinia translocon assembly within host membranesQ41458033
Dissection of homologous translocon operons reveals a distinct role for YopD in type III secretion by Yersinia pseudotuberculosisQ41465782
IpaC from Shigella and SipC from Salmonella possess similar biochemical properties but are functionally distinctQ41474021
Functional conservation of the effector protein translocators PopB/YopB and PopD/YopD of Pseudomonas aeruginosa and Yersinia pseudotuberculosisQ41484833
YopD of Yersinia pseudotuberculosis is translocated into the cytosol of HeLa epithelial cells: evidence of a structural domain necessary for translocationQ41485145
Translocation of a hybrid YopE-adenylate cyclase from Yersinia enterocolitica into HeLa cellsQ41497627
The Shigella T3SS needle transmits a signal for MxiC release, which controls secretion of effectorsQ42168584
Shigella invasion of macrophage requires the insertion of IpaC into the host plasma membrane. Functional analysis of IpaC.Q43645358
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
ImageQuantQ112270642
P433issue3
P304page(s)e1005530
P577publication date2016-03-29
P1433published inPLOS PathogensQ283209
P1476titleThe Type III Secretion Translocation Pore Senses Host Cell Contact
P478volume12

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cites work (P2860)
Q41006822A dynamic and adaptive network of cytosolic interactions governs protein export by the T3SS injectisome
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Q40185364Exploiting a host-commensal interaction to promote intestinal barrier function and enteric pathogen tolerance.
Q90651729Guanylate binding proteins facilitate caspase-11-dependent pyroptosis in response to type 3 secretion system-negative Pseudomonas aeruginosa
Q90400965Life After Secretion-Yersinia enterocolitica Rapidly Toggles Effector Secretion and Can Resume Cell Division in Response to Changing External Conditions
Q47254500Novel insights into the mechanism of SepL-mediated control of effector secretion in enteropathogenic Escherichia coli.
Q37644028Piericidin A1 Blocks Yersinia Ysc Type III Secretion System Needle Assembly
Q40166358Regulation of Type III Secretion of Translocon and Effector Proteins by the EsaB/EsaL/EsaM Complex in Edwardsiella tarda.
Q40403205The Amino-Terminal Part of the Needle-Tip Translocator LcrV of Yersinia pseudotuberculosis Is Required for Early Targeting of YopH and In vivo Virulence
Q88446234The Pseudomonas aeruginosa type III secretion translocator PopB assists the insertion of the PopD translocator into host cell membranes
Q92355802Topological Analysis of the Type 3 Secretion System Translocon Pore Protein IpaC following Its Native Delivery to the Plasma Membrane during Infection
Q28074332Type Three Secretion System in Attaching and Effacing Pathogens

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