Ionizing radiation and restriction enzymes induce microhomology-mediated illegitimate recombination in Saccharomyces cerevisiae

scientific article

Ionizing radiation and restriction enzymes induce microhomology-mediated illegitimate recombination in Saccharomyces cerevisiae is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/NAR/GKM442
P8608Fatcat IDrelease_c2m4lctcpzfgzk6q65rlu2exka
P932PMC publication ID1976441
P698PubMed publication ID17652322
P5875ResearchGate publication ID6187070

P2093author name stringRobert H Schiestl
Markus Kiechle
Palaniyandi Manivasakam
Cecilia Y Chan
P2860cites workAlpha-galactosidase A gene rearrangements causing Fabry disease. Identification of short direct repeats at breakpoints in an Alu-rich geneQ24304284
Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathwaysQ24561996
Adaptive mutation: the uses of adversityQ24596056
Improved method for high efficiency transformation of intact yeast cellsQ28131608
Genome-wide hypermutation in a subpopulation of stationary-phase cells underlies recombination-dependent adaptive mutationQ33886793
Site-specific recombination determined by I-SceI, a mitochondrial group I intron-encoded endonuclease expressed in the yeast nucleusQ33959067
Enzyme action at 3' termini of ionizing radiation-induced DNA strand breaksQ34257112
Ku-dependent and Ku-independent end-joining pathways lead to chromosomal rearrangements during double-strand break repair in Saccharomyces cerevisiae.Q34617309
Relaxation of recognition sequence of specific endonuclease HindIII.Q34684351
Integration of DNA fragments by illegitimate recombination in Saccharomyces cerevisiaeQ34838158
Nonadaptive mutations occur on the F' episome during adaptive mutation conditions in Escherichia coliQ35620439
Formation of large deletions by illegitimate recombination in the HPRT gene of primary human fibroblastsQ36105241
Topoisomerase I involvement in illegitimate recombination in Saccharomyces cerevisiaeQ36558770
Two different types of double-strand breaks in Saccharomyces cerevisiae are repaired by similar RAD52-independent, nonhomologous recombination eventsQ36646569
Mechanisms of nonhomologous recombination in mammalian cellsQ36894382
Nonhomologous recombination in mammalian cells: role for short sequence homologies in the joining reactionQ36901365
Repair of sequence-specific 125I-induced double-strand breaks by nonhomologous DNA end joining in mammalian cell-free extractsQ38292505
Spi(-) selection: An efficient method to detect gamma-ray-induced deletions in transgenic miceQ38321193
Review of repair kinetics for DNA damage induced in eukaryotic cells in vitro by ionizing radiationQ38636715
DNA length dependence of the single-strand annealing pathway and the role of Saccharomyces cerevisiae RAD59 in double-strand break repairQ39454427
DNA double-strand break repair in cell-free extracts from Ku80-deficient cells: implications for Ku serving as an alignment factor in non-homologous DNA end joiningQ39543261
Nonhomologous end joining during restriction enzyme-mediated DNA integration in Saccharomyces cerevisiaeQ39574713
Promoter-trapping in Saccharomyces cerevisiae by radiation-assisted fragment insertionQ39696592
Yeast Mre11 and Rad1 proteins define a Ku-independent mechanism to repair double-strand breaks lacking overlapping end sequencesQ40173836
Micro-homology mediated PCR targeting inSaccharomyces cerevisiaeQ40395047
Mechanism of intramolecular recyclization and deletion formation following transformation of Escherichia coli with linearized plasmid DNA.Q40419621
In pursuit of a molecular mechanism for adaptive mutation.Q40575363
Camptothecin enhances random integration of transfected DNA into the genome of mammalian cellsQ40906168
Bleomycin enhances random integration of transfected DNA into a human genomeQ40996519
DNA damaging agents improve stable gene transfer efficiency in mammalian cellsQ41057702
Ionizing radiation greatly improves gene transfer efficiency in mammalian cellsQ41168436
Gene deletions causing human genetic disease: mechanisms of mutagenesis and the role of the local DNA sequence environmentQ41182021
DNA topoisomerase II inhibitors enhance random integration of transfected vectors into human chromosomesQ41186580
Molecular analysis of hypoxanthine phosphoribosyltransferase gene deletions induced by alpha- and X-radiation in human lymphoblastoid cellsQ41404928
Nonhomologous recombination in human cellsQ41497376
Role of DNA ligase in the illegitimate recombination that generates lambdabio-transducing phages in Escherichia coliQ42542586
Transformation of Saccharomyces cerevisiae with nonhomologous DNA: illegitimate integration of transforming DNA into yeast chromosomes and in vivo ligation of transforming DNA to mitochondrial DNA sequencesQ43182551
DNA-mediated gene transfer efficiency is enhanced by ionizing and ultraviolet irradiation of rodent cells in vitro. I. Kinetics of enhancementQ43593367
Nonhomologous recombination in the human genome: deletions in the human factor VIII geneQ45881405
Mechanisms involved in rejoining DNA double-strand breaks induced by ionizing radiation and restriction enzymesQ46135729
Sequences of junction fragments in the deletion-prone region of the dystrophin geneQ48226338
Molecular analysis of deletions in the human beta-globin gene cluster: deletion junctions and locations of breakpointsQ48275942
Two modules from the hypersuppressive rho- mitochondrial DNA are required for plasmid replication in yeastQ48387012
Computer simulation of pulsed field gel runs allows the quantitation of radiation-induced double-strand breaks in yeast.Q51652171
Microbiology and evolution. Modulating mutation rates in the wild.Q54524357
Recombination in adaptive mutation.Q54635736
Suppression of gamma ray-induced illegitimate recombination in Escherichia coli by the DNA-binding protein H-NSQ64388137
Isolation of Dictyostelium discoideum cytokinesis mutants by restriction enzyme-mediated integration of the blasticidin S resistance markerQ72384482
Minimum length of sequence homology required for in vivo cloning by homologous recombination in yeastQ73809373
Identifying tagged transposon insertion sites in yeast by direct genomic sequencingQ73931523
P433issue15
P407language of work or nameEnglishQ1860
P921main subjectSaccharomyces cerevisiaeQ719725
P304page(s)5051-5059
P577publication date2007-07-25
P1433published inNucleic Acids ResearchQ135122
P1476titleIonizing radiation and restriction enzymes induce microhomology-mediated illegitimate recombination in Saccharomyces cerevisiae
P478volume35

Reverse relations

cites work (P2860)
Q34036296Breakpoint characterization of a novel large intragenic deletion of MUTYH detected in a MAP patient: case report
Q47815999Ends-in vs. ends-out targeted insertion mutagenesis in Saccharomyces castellii
Q56771011Expanding CEP290 mutational spectrum in ciliopathies
Q33642312Genomic characterization of large rearrangements of the LDLR gene in Czech patients with familial hypercholesterolemia
Q37154264Germline CDH1 deletions in hereditary diffuse gastric cancer families
Q37259549Ionizing radiation induces microhomology-mediated end joining in trans in yeast and mammalian cells
Q24650544Ionizing radiation: how fungi cope, adapt, and exploit with the help of melanin
Q29614424MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings
Q45258402Mechanism of random integration of foreign DNA in transgenic mice
Q39311928Numtogenesis as a mechanism for development of cancer
Q37341165Rad1, rad10 and rad52 mutations reduce the increase of microhomology length during radiation-induced microhomology-mediated illegitimate recombination in saccharomyces cerevisiae
Q92148871Rapid functional activation of a horizontally transferred eukaryotic gene in a bacterial genome in the absence of selection
Q36591704Requirement of POL3 and POL4 on non-homologous and microhomology-mediated end joining in rad50/xrs2 mutants of Saccharomyces cerevisiae.
Q33366520Small deletion variants have stable breakpoints commonly associated with alu elements.
Q34127303Ty1 integrase overexpression leads to integration of non-Ty1 DNA fragments into the genome of Saccharomyces cerevisiae

Search more.