Pyridoxine supplementation does not alter in vivo kinetics of one-carbon metabolism but modifies patterns of one-carbon and tryptophan metabolites in vitamin B-6-insufficient oral contraceptive users

scientific article

Pyridoxine supplementation does not alter in vivo kinetics of one-carbon metabolism but modifies patterns of one-carbon and tryptophan metabolites in vitamin B-6-insufficient oral contraceptive users is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3945/AJCN.115.113159
P932PMC publication ID4548178
P698PubMed publication ID26201817
P5875ResearchGate publication ID280391495

P50authorPer Magne UelandQ11995248
Øivind MidttunQ38624967
Jesse F. GregoryQ41844201
Maria A RalatQ92397013
Luisa Rios-AvilaQ117216877
Bonnie CoatsQ117216887
P2093author name stringPeter W Stacpoole
Yueh-Yun Chi
P2860cites workGut flora metabolism of phosphatidylcholine promotes cardiovascular diseaseQ24601951
Inflammation causes tissue-specific depletion of vitamin B6.Q24812811
Kynurenines in the mammalian brain: when physiology meets pathologyQ27003296
The glycine cleavage system: Composition, reaction mechanism, and physiological significanceQ28243267
Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulationQ28283087
Effects of vitamin B-6 deficiency and tryptophan loading on urinary excretion of tryptophan metabolites in mammalsQ28330507
Activities of hepatic cytosolic and mitochondrial forms of serine hydroxymethyltransferase and hepatic glycine concentration are affected by vitamin B-6 intake in ratsQ28575409
Visualization of GC/TOF-MS-based metabolomics data for identification of biochemically interesting compounds using OPLS class modelsQ31137205
Multivariate paired data analysis: multilevel PLSDA versus OPLSDA.Q33546330
Targeted metabolomics and mathematical modeling demonstrate that vitamin B-6 restriction alters one-carbon metabolism in cultured HepG2 cellsQ33839922
Vitamin B-6: a status reportQ34262523
Evidence for increased catabolism of vitamin B-6 during systemic inflammationQ34419296
Metabolite profile analysis reveals association of vitamin B-6 with metabolites related to one-carbon metabolism and tryptophan catabolism but not with biomarkers of inflammation in oral contraceptive users and reveals the effects of oral contraceptQ34684231
Low circulating folate and vitamin B6 concentrations: risk factors for stroke, peripheral vascular disease, and coronary artery disease. European COMAC GroupQ34745701
Metabolomic analysis reveals extended metabolic consequences of marginal vitamin B-6 deficiency in healthy human subjectsQ34775573
Moderate vitamin B-6 restriction does not alter postprandial methionine cycle rates of remethylation, transmethylation, and total transsulfuration but increases the fractional synthesis rate of cystathionine in healthy young men and women.Q34802087
Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase.Q36376561
A mathematical model of tryptophan metabolism via the kynurenine pathway provides insights into the effects of vitamin B-6 deficiency, tryptophan loading, and induction of tryptophan 2,3-dioxygenase on tryptophan metabolitesQ37094907
Moderate dietary vitamin B-6 restriction raises plasma glycine and cystathionine concentrations while minimally affecting the rates of glycine turnover and glycine cleavage in healthy men and womenQ37105818
Metabolite profile analysis reveals functional effects of 28-day vitamin B-6 restriction on one-carbon metabolism and tryptophan catabolic pathways in healthy men and womenQ37229200
Metabolic characteristics and importance of the universal methionine salvage pathway recycling methionine from 5'-methylthioadenosine.Q37641189
Associations of plasma kynurenines with risk of acute myocardial infarction in patients with stable angina pectorisQ39071200
3-Hydroxyanthranilic acid, an L-tryptophan metabolite, induces apoptosis in monocyte-derived cells stimulated by interferon-gammaQ40801034
A mathematical model gives insights into the effects of vitamin B-6 deficiency on 1-carbon and glutathione metabolism.Q41912932
Asymmetric dimethylarginine (ADMA): a novel risk factor for endothelial dysfunction: its role in hypercholesterolemiaQ42538581
Measurement of intracellular sulfur amino acid metabolism in humansQ43606115
Low vitamin B(6) plasma levels, a risk factor for thrombosis, in inflammatory bowel disease: role of inflammation and correlation with acute phase reactantsQ44277481
Abnormal vitamin B(6) status is associated with severity of symptoms in patients with rheumatoid arthritisQ44394232
Low Vitamin B6 but Not Homocyst(e)ine Is Associated With Increased Risk of Stroke and Transient Ischemic Attack in the Era of Folic Acid Grain FortificationQ44435312
Quantitative study in vivo of methionine cycle in humans using [methyl-2H3]- and [1-13C]methionineQ44494347
Tracer-derived total and folate-dependent homocysteine remethylation and synthesis rates in humans indicate that serine is the main one-carbon donorQ44618189
Blood levels of homocysteine, folate, vitamin B6 and B12 in women using oral contraceptives compared to non-usersQ44794623
Substrate product ratios of enzymes in the kynurenine pathway measured in plasma as indicators of functional vitamin B-6 statusQ44869152
Pyridoxine Effects on Cystathionine Synthase in Rat LiverQ44985792
Oral estradiol decreases plasma homocysteine, vitamin B6, and albumin in postmenopausal women but does not change the whole-body homocysteine remethylation and transmethylation fluxQ45238670
Quantitative profiling of biomarkers related to B-vitamin status, tryptophan metabolism and inflammation in human plasma by liquid chromatography/tandem mass spectrometryQ46065776
Effects of third-generation oral contraceptives on high-sensitivity C-reactive protein and homocysteine in young womenQ46672480
Low plasma vitamin B-6 concentrations and modulation of coronary artery disease riskQ47438621
Effect of Vitamin B6 Depletion in Adult Man on the Plasma Concentration and the Urinary Excretion of Free Amino AcidsQ51682786
Plasma glutathione and cystathionine concentrations are elevated but cysteine flux is unchanged by dietary vitamin B-6 restriction in young men and women.Q51822809
Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and CholineQ56092268
Association of plasma B-6 vitamers with systemic markers of inflammation before and after pyridoxine treatment in patients with stable angina pectorisQ59275989
Low Plasma Vitamin B-6 Status Affects Metabolism through the Kynurenine Pathway in Cardiovascular Patients with Systemic InflammationQ59275991
Rapid and accurate HPLC assay for plasma total homocysteine and cysteine in a clinical laboratory settingQ64132337
Effect of Vitamin B6 Depletion in Adult Man on the Excretion of Cystathionine and Other Methionine MetabolitesQ71412014
Glycine Metabolism in Vitamin B6-deficient and Deoxypyridoxine-treated RatsQ72419570
FREE AMINO ACIDS IN PLASMA AND TISSUES OF RATS FED A VITAMIN B6-DEFICIENT DIETQ76795164
Low pyridoxal 5'-phosphate is associated with increased risk of coronary artery diseaseQ79256266
Vitamin B-6 deficiency suppresses the hepatic transsulfuration pathway but increases glutathione concentration in rats fed AIN-76A or AIN-93G dietsQ79954676
Plasma pyridoxal 5'-phosphate in the US population: the National Health and Nutrition Examination Survey, 2003-2004Q81247681
Dietary vitamin B-6 restriction does not alter rates of homocysteine remethylation or synthesis in healthy young women and menQ81498008
Effect of oral contraceptive therapy on homocysteine and C-reactive protein levels in women: an observational studyQ82788880
Stability of pyridoxal-5-phosphate semicarbazone: applications in plasma vitamin B6 analysis and population surveys of vitamin B6 nutritional statusQ93633948
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectvitamin BQ183206
pyridoxineQ423746
P304page(s)616-625
P577publication date2015-07-22
P1433published inAmerican Journal of Clinical NutritionQ7713500
P1476titlePyridoxine supplementation does not alter in vivo kinetics of one-carbon metabolism but modifies patterns of one-carbon and tryptophan metabolites in vitamin B-6-insufficient oral contraceptive users
P478volume102

Reverse relations

cites work (P2860)
Q92593148A novel nutritional supplement to reduce plasma homocysteine in nonpregnant women: A randomised controlled trial in The Gambia
Q51279969Trimethylamine-N-oxide and its biological variations in vegetarians.
Q36984149Vitamin B6 nutritional status and cellular availability of pyridoxal 5'-phosphate govern the function of the transsulfuration pathway's canonical reactions and hydrogen sulfide production via side reactions

Search more.