Moderate vitamin B-6 restriction does not alter postprandial methionine cycle rates of remethylation, transmethylation, and total transsulfuration but increases the fractional synthesis rate of cystathionine in healthy young men and women.

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Moderate vitamin B-6 restriction does not alter postprandial methionine cycle rates of remethylation, transmethylation, and total transsulfuration but increases the fractional synthesis rate of cystathionine in healthy young men and women. is …
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scholarly articleQ13442814

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P356DOI10.3945/JN.110.134197
P932PMC publication ID3077887
P698PubMed publication ID21430249
P5875ResearchGate publication ID50831637

P50authorJesse F. GregoryQ41844201
Yvonne LamersQ43146345
P2093author name stringPeter W Stacpoole
Eoin P Quinlivan
Bonnie Coats
Maria Ralat
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Activities of hepatic cytosolic and mitochondrial forms of serine hydroxymethyltransferase and hepatic glycine concentration are affected by vitamin B-6 intake in ratsQ28575409
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Low circulating folate and vitamin B6 concentrations: risk factors for stroke, peripheral vascular disease, and coronary artery disease. European COMAC GroupQ34745701
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Moderate dietary vitamin B-6 restriction raises plasma glycine and cystathionine concentrations while minimally affecting the rates of glycine turnover and glycine cleavage in healthy men and womenQ37105818
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Response of vitamin B-6 content of muscle to changes in vitamin B-6 intake in men.Q43665766
Deficiencies of folate and vitamin B(6) exert distinct effects on homocysteine, serine, and methionine kineticsQ43794362
Homocysteine, vitamin B6, and vascular disease in AD patientsQ44009306
Low Vitamin B6 but Not Homocyst(e)ine Is Associated With Increased Risk of Stroke and Transient Ischemic Attack in the Era of Folic Acid Grain FortificationQ44435312
Quantitative study in vivo of methionine cycle in humans using [methyl-2H3]- and [1-13C]methionineQ44494347
Tracer-derived total and folate-dependent homocysteine remethylation and synthesis rates in humans indicate that serine is the main one-carbon donorQ44618189
Primed, constant infusion with [2H3]serine allows in vivo kinetic measurement of serine turnover, homocysteine remethylation, and transsulfuration processes in human one-carbon metabolism.Q46015856
Low plasma vitamin B-6 concentrations and modulation of coronary artery disease riskQ47438621
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Effect of vitamin B-6 deficiency on fasting plasma homocysteine concentrations.Q51605451
Plasma glutathione and cystathionine concentrations are elevated but cysteine flux is unchanged by dietary vitamin B-6 restriction in young men and women.Q51822809
Rapid and accurate HPLC assay for plasma total homocysteine and cysteine in a clinical laboratory settingQ64132337
[1-13C; methyl-2H3]methionine kinetics in humans: methionine conservation and cystine sparingQ68507565
A tracer investigation of obligatory oxidative amino acid losses in healthy, young adultsQ73026234
Methionine and cysteine kinetics at different intakes of methionine and cysteine in elderly men and womenQ77078046
Low pyridoxal 5'-phosphate is associated with increased risk of coronary artery diseaseQ79256266
Vitamin B-6 deficiency suppresses the hepatic transsulfuration pathway but increases glutathione concentration in rats fed AIN-76A or AIN-93G dietsQ79954676
Plasma folate, vitamin B-6, vitamin B-12, and risk of breast cancer in womenQ80836616
Plasma pyridoxal 5'-phosphate in the US population: the National Health and Nutrition Examination Survey, 2003-2004Q81247681
Methylenetetrahydrofolate reductase 677C->T polymorphism and folate status affect one-carbon incorporation into human DNA deoxynucleosidesQ81448437
Dietary vitamin B-6 restriction does not alter rates of homocysteine remethylation or synthesis in healthy young women and menQ81498008
Stability of pyridoxal-5-phosphate semicarbazone: applications in plasma vitamin B6 analysis and population surveys of vitamin B6 nutritional statusQ93633948
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectvitamin BQ183206
P304page(s)835-842
P577publication date2011-03-23
P1433published inJournal of NutritionQ3186931
P1476titleModerate vitamin B-6 restriction does not alter postprandial methionine cycle rates of remethylation, transmethylation, and total transsulfuration but increases the fractional synthesis rate of cystathionine in healthy young men and women
P478volume141

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cites work (P2860)
Q92593148A novel nutritional supplement to reduce plasma homocysteine in nonpregnant women: A randomised controlled trial in The Gambia
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Q35611000Marginal biotin deficiency can be induced experimentally in humans using a cost-effective outpatient design
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