The influence of serum methotrexate concentrations and drug dosage on outcome in childhood acute lymphoblastic leukaemia

scientific article published on July 1, 1991

The influence of serum methotrexate concentrations and drug dosage on outcome in childhood acute lymphoblastic leukaemia is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/BJC.1991.263
P953full work available at URLhttp://www.nature.com/articles/bjc1991263
http://www.nature.com/articles/bjc1991263.pdf
https://europepmc.org/articles/PMC1977331
https://europepmc.org/articles/PMC1977331?pdf=render
P932PMC publication ID1977331
P698PubMed publication ID1854617
P5875ResearchGate publication ID21300601

P2093author name stringA. W. Craft
A. D. Pearson
J. M. Chessells
S. Mills
D. R. Long
H. A. Amineddine
M. Yule
P2860cites workDose-response effect of adjuvant chemotherapy in breast cancerQ28283048
Childhood leukaemia: a relationship between intracellular 6-mercaptopurine metabolites and neutropeniaQ34513265
Polyglutamation of methotrexate. Is methotrexate a prodrug?Q34552178
Oral methotrexate is as effective as intramuscular in maintenance therapy of acute lymphoblastic leukaemiaQ35603604
Absorption of methotrexate under standardized conditions in children with acute lymphoblastic leukaemiaQ36044389
The importance of dose intensity in chemotherapy of metastatic breast cancerQ40190080
Unpredictable serum levels after oral methotrexate in children with acute lymphoblastic leukaemiaQ40624289
Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts at diagnosis of childhood acute lymphoblastic leukemia: a pilot prognostic factor analysisQ41762709
Drug dosage and remission duration in childhood lymphocytic leukemiaQ44949634
A reliable method for evaluating drug compliance in children with cancerQ46215445
Pharmacokinetics of oral methotrexate in children.Q51647048
Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemiaQ68092294
Pharmacokinetics of oral and intramuscular methotrexate in children with acute lymphoblastic leukaemiaQ68202669
Clinical pharmacodynamics of high-dose methotrexate in acute lymphocytic leukemia. Identification of a relation between concentration and effectQ68719349
A dose and time response analysis of the treatment of Hodgkin's disease with MOPP chemotherapyQ71248649
Methotrexate systemic clearance influences probability of relapse in children with standard-risk acute lymphocytic leukaemiaQ72571805
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
oncologyQ162555
methotrexateQ422232
P304page(s)169-173
P577publication date1991-07-01
P1433published inBritish Journal of CancerQ326309
P1476titleThe influence of serum methotrexate concentrations and drug dosage on outcome in childhood acute lymphoblastic leukaemia
P478volume64

Reverse relations

cites work (P2860)
Q40791634An odyssey in search of a cure: the evolution of treatment of childhood acute lymphoblastic leukemia in the United Kingdom.
Q40736715Biology and treatment of acute lymphoblastic leukemia
Q41532868Does pharmacokinetic variability influence the efficacy of high-dose methotrexate for the treatment of children with acute lymphoblastic leukemia: what can we learn from small studies?
Q56391087Dose calculation of anticancer drugs
Q37098221Induction of acute lymphocytic leukemia differentiation by maintenance therapy
Q34797124Maintenance treatment and shared care in lymphoblastic leukaemia
Q27023839Mercaptopurine/Methotrexate maintenance therapy of childhood acute lymphoblastic leukemia: clinical facts and fiction
Q44272964Modified BFM protocol for childhood acute lymphoblastic leukemia: a retrospective analysis
Q73514183On the prognostic value of systemic methotrexate clearance in childhood acute lymphocytic leukemia
Q42689021Pharmacokinetics of HD-MTX in infants, children, and adolescents with non-B acute lymphoblastic leukemia
Q52384093Pharmacokinetics of high-dose methotrexate in adult osteogenic sarcoma.
Q77761715Practical treatment guide for dose individualisation in cancer chemotherapy
Q71041217Randomized comparison of moderate-dose methotrexate infusions to oral methotrexate in children with intermediate risk acute lymphoblastic leukemia: a Childrens Cancer Group study
Q73596981Variability in methotrexate serum and cerebrospinal fluid pharmacokinetics in children with acute lymphocytic leukemia: relation to assay methodology and physiological variables