scholarly article | Q13442814 |
P2093 | author name string | Kirk C Hansen | |
Jeffrey T Holt | |||
Steven M Anderson | |||
Traci R Lyons | |||
Andrew C Nelson | |||
Christian D Young | |||
P2860 | cites work | Estrogen receptor alpha rapidly activates the IGF-1 receptor pathway | Q22253479 |
BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage | Q24292278 | ||
Growth factor signaling pathways modulate BRCA1 repression of estrogen receptor-alpha activity | Q24306083 | ||
DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains | Q24306945 | ||
BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A | Q24315124 | ||
BRCA1 and BRCA2 mRNA levels are coordinately elevated in human breast cancer cells in response to estrogen | Q24316813 | ||
Identification of a RING protein that can interact in vivo with the BRCA1 gene product | Q24324342 | ||
BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site | Q24554478 | ||
Negative Regulation of AKT Activation by BRCA1 | Q24644153 | ||
Cell cycle-dependent colocalization of BARD1 and BRCA1 proteins in discrete nuclear domains | Q24645684 | ||
BRCA1 is a component of the RNA polymerase II holoenzyme | Q24675704 | ||
Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining | Q24682187 | ||
Structure of a BRCA1-BARD1 heterodimeric RING-RING complex | Q27635007 | ||
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery | Q27860586 | ||
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications | Q27860709 | ||
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1 | Q28115843 | ||
Repeated observation of breast tumor subtypes in independent gene expression data sets | Q28131820 | ||
Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response | Q28140763 | ||
Genetic analysis of BRCA1 function in a defined tumor cell line | Q28142643 | ||
Heregulin induces phosphorylation of BRCA1 through phosphatidylinositol 3-Kinase/AKT in breast cancer cells | Q28146113 | ||
The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity | Q28215490 | ||
Linkage of early-onset familial breast cancer to chromosome 17q21 | Q28268902 | ||
PI3-kinase in concert with Src promotes the S-phase entry of oestradiol-stimulated MCF-7 cells | Q28363087 | ||
Brca1 controls homology-directed DNA repair | Q29614844 | ||
The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse | Q29618622 | ||
Hallmarks of 'BRCAness' in sporadic cancers | Q29618825 | ||
Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage | Q29619360 | ||
Regulation of the Pro-apoptotic scaffolding protein POSH by Akt. | Q30157958 | ||
Interaction of oestrogen receptor with the regulatory subunit of phosphatidylinositol-3-OH kinase | Q30439814 | ||
The breast cancer susceptibility gene BRCA1 regulates progesterone receptor signaling in mammary epithelial cells | Q33652431 | ||
Synergistic suppression of apoptosis in salivary acinar cells by IGF1 and EGF | Q33911108 | ||
Emerging roles of BRCA1 alternative splicing | Q33919195 | ||
BRCA1 transcriptionally regulates genes involved in breast tumorigenesis | Q34064538 | ||
Regulation of BRCA1, BRCA2 and BARD1 intracellular trafficking | Q34444026 | ||
Hormonal prevention of hereditary breast cancer | Q34497393 | ||
Activation of estrogen signaling pathways collaborates with loss of Brca1 to promote development of ERalpha-negative and ERalpha-positive mammary preneoplasia and cancer | Q34609774 | ||
Regulation of progesterone receptor signaling by BRCA1 in mammary cancer | Q34652156 | ||
Hormone-dependent regulation of BRCA1 in human breast cancer cells. | Q34719862 | ||
IGF-I, GH, and sex steroid effects in normal mammary gland development | Q34889024 | ||
Estrogen receptor alpha is a putative substrate for the BRCA1 ubiquitin ligase | Q35749504 | ||
Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity | Q35865833 | ||
Phosphatidylinositol 3-kinase/Akt signaling enhances nuclear localization and transcriptional activity of BRCA1 | Q35924811 | ||
Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes | Q36032594 | ||
Regulation of signal transduction pathways by estrogen and progesterone | Q36041030 | ||
Prevention and management of hereditary breast cancer | Q36065462 | ||
BRCA1 is a cell cycle-regulated nuclear phosphoprotein | Q36648552 | ||
BRCA1 inhibits membrane estrogen and growth factor receptor signaling to cell proliferation in breast cancer | Q36732507 | ||
IGF ligand and receptor regulation of mammary development | Q37149891 | ||
Crosstalk between IGF1R and estrogen receptor signaling in breast cancer. | Q37323603 | ||
Prevention of Brca1-mediated mammary tumorigenesis in mice by a progesterone antagonist | Q40202330 | ||
Ubiquitination and proteasomal degradation of the BRCA1 tumor suppressor is regulated during cell cycle progression. | Q40551207 | ||
Estrogen receptors: bioactivities and interactions with cell signaling pathways | Q41096911 | ||
Reduction of BRCA1 expression in sporadic ovarian cancer | Q41720959 | ||
BRCA1 expression restores radiation resistance in BRCA1-defective cancer cells through enhancement of transcription-coupled DNA repair | Q42473523 | ||
Identification of BRCA1-IRIS, a BRCA1 locus product | Q42636849 | ||
Adenovirus transduction of 3T3-L1 cells | Q42831133 | ||
An adenoviral vector containing an arg-gly-asp (RGD) motif in the fiber knob enhances protein product levels from transgenes refractory to expression | Q44495836 | ||
Adenovirus E4 gene promotes selective endothelial cell survival and angiogenesis via activation of the vascular endothelial-cadherin/Akt signaling pathway | Q44683477 | ||
Protein kinase C betaII regulates Akt phosphorylation on Ser-473 in a cell type- and stimulus-specific fashion. | Q45057108 | ||
IGF and insulin receptor signaling in breast cancer. | Q46240548 | ||
Estrogen upregulation of BRCA1 expression with no effect on localization | Q47878271 | ||
BRCA1 expression is not directly responsive to estrogen | Q48055063 | ||
BRCA1 protein products ... Functional motifs... | Q48062839 | ||
Activation of estrogen receptor-mediated gene transcription by IGF-I in human breast cancer cells. | Q52523736 | ||
Gene-Expression Profiles in Hereditary Breast Cancer | Q57240053 | ||
BRCA1 Inhibition of Estrogen Receptor Signaling in Transfected Cells | Q60568779 | ||
Location of BRCA1 in human breast and ovarian cancer cells | Q70998780 | ||
Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression | Q72345882 | ||
Effect of bilateral oophorectomy on mammary tumor formation in BRCA1 mutant mice | Q94461300 | ||
P433 | issue | 1-2 | |
P304 | page(s) | 129-142 | |
P577 | publication date | 2010-01-18 | |
P1433 | published in | Molecular and Cellular Endocrinology | Q1573600 |
P1476 | title | AKT regulates BRCA1 stability in response to hormone signaling | |
P478 | volume | 319 |
Q36534034 | "DNA Binding Region" of BRCA1 Affects Genetic Stability through modulating the Intra-S-Phase Checkpoint |
Q35169608 | AKT1/BRCA1 in the control of homologous recombination and genetic stability: the missing link between hereditary and sporadic breast cancers |
Q64948494 | BRCA Genes: The Role in Genome Stability, Cancer Stemness and Therapy Resistance. |
Q37720033 | BRCA1 regulates insulin-like growth factor 1 receptor levels in ovarian cancer |
Q34481443 | Connection between Tumor Suppressor BRCA1 and PTEN in Damaged DNA Repair |
Q57493678 | Elucidating the novel BRCA1 function as a non-genomic metabolic restraint in ER-positive breast cancer cell lines |
Q35961713 | Genetic variation in IGF2 and HTRA1 and breast cancer risk among BRCA1 and BRCA2 carriers |
Q34764674 | Histone methyltransferase EZH2 induces Akt-dependent genomic instability and BRCA1 inhibition in breast cancer |
Q38062611 | IGF-1 and BRCA1 signalling pathways in familial cancer |
Q36652248 | Inhibition of constitutively activated phosphoinositide 3-kinase/AKT pathway enhances antitumor activity of chemotherapeutic agents in breast cancer susceptibility gene 1-defective breast cancer cells |
Q52644526 | New Insights into Protein Kinase B/Akt Signaling: Role of Localized Akt Activation and Compartment-Specific Target Proteins for the Cellular Radiation Response. |
Q37001693 | Power of PTEN/AKT: Molecular switch between tumor suppressors and oncogenes |
Q37611723 | Reversing Platinum Resistance in High-Grade Serous Ovarian Carcinoma: Targeting BRCA and the Homologous Recombination System |
Q54274892 | The PI3K/AKT/mTOR interactive pathway. |
Q27027457 | Therapeutic targeting of replicative immortality |
Q34260212 | Transcriptional and posttranslational regulation of insulin-like growth factor binding protein-3 by Akt3. |
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