Nitroimidazole adducts as markers for tissue hypoxia: mechanistic studies in aerobic normal tissues and tumour cells

scientific article published on December 1, 1992

Nitroimidazole adducts as markers for tissue hypoxia: mechanistic studies in aerobic normal tissues and tumour cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/BJC.1992.418
P953full work available at URLhttps://europepmc.org/articles/PMC1978026
https://europepmc.org/articles/PMC1978026?pdf=render
https://www.nature.com/articles/bjc1992418.pdf
http://www.nature.com/articles/bjc1992418
http://www.nature.com/articles/bjc1992418.pdf
P932PMC publication ID1978026
P698PubMed publication ID1280990
P5875ResearchGate publication ID21874694

P2093author name stringL. I. Wiebe
A. J. Franko
M. B. Parliament
P2860cites workThe effect of hypobaric hypoxia on misonidazole binding in normal and tumour-bearing mice.Q33471029
Effect of nicotinamide on the microregional heterogeneity of oxygen delivery within a murine tumorQ33840709
The potentiation of radiation damage by nicotinamide in the SCCVII tumour in vivoQ33850001
NAD(P)H nitroblue tetrazolium reductase levels in apparently normoxic tissues: a histochemical study correlating enzyme activity with binding of radiolabelled misonidazoleQ35981697
Non-invasive assessment of human tumour hypoxia with 123I-iodoazomycin arabinoside: preliminary report of a clinical studyQ35992946
A marker for hypoxic cells in tumours with potential clinical applicabilityQ36045083
Binding of 14C-misonidazole to hypoxic cells in V79 spheroidsQ36046546
Microscopic distribution of misonidazole in mouse tissuesQ36466982
Deficient activation by a human cell strain leads to mitomycin resistance under aerobic but not hypoxic conditionsQ36467315
Comparison between the binding of [3H]misonidazole and AF-2 in Chinese hamster V79 spheroidsQ36492299
The use of fluorocarbon emulsions in cancer radiotherapyQ37704002
Hypoxic Sensitizers — Implications for Radiation TherapyQ38039930
Misonidazole and other hypoxia markers: metabolism and applicationsQ39741419
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Misonidazole binding in murine liver tissue: a marker for cellular hypoxia in vivoQ41787769
Enhancement of mitomycin C cytotoxicity to hypoxic tumor cells by dicoumarol in vivo and in vitroQ41839909
Distribution of pimonidazole and RSU 1069 in tumour and normal tissuesQ41913928
DT-diaphorase: questionable role in mitomycin C resistance, but a target for novel bioreductive drugs?Q42142796
The labelling of EMT-6 tumours in BALB/C mice with 14C-misonidazoleQ42253112
A new mouse tumor model system (RIF-1) for comparison of end-point studiesQ42799818
Is misonidazole binding to mouse tissues a measure of cellular pO2?Q48194161
Distribution and tumor penetration properties of a radiosensitizer 2-[14C] misonidazole (Ro 07-0582), in mice and rats as studied by whole-body autoradiographyQ48400674
Nimorazole as a hypoxic radiosensitizer in the treatment of supraglottic larynx and pharynx carcinoma. First report from the Danish Head and Neck Cancer Study (DAHANCA) protocol 5-85.Q50545311
Clinical trials with etanidazole (SR-2508) by the radiation therapy oncology group (RTOG)Q67898813
Radioiodinated 1-(5-iodo-5-deoxy-beta-D-arabinofuranosyl)-2-nitroimidazole (iodoazomycin arabinoside: IAZA): a novel marker of tissue hypoxiaQ67958100
Tissue distribution of 14C- and 3H-labelled misonidazole in the tumor-bearing mouseQ68708575
Oxygen dependence of binding of misonidazole to rodent and human tumors in vitroQ69395040
Covalent binding of a fluorinated 2-nitroimidazole to EMT-6 tumors in Balb/C mice: detection by F-19 nuclear magnetic resonance at 2.35 TQ69592519
In vitro binding of 14C-misonidazole to hepatocytes and hepatoma cellsQ69592521
Radiolabelled fluoromisonidazole as an imaging agent for tumor hypoxiaQ69785312
SR 4233: a tumor specific radiosensitizer active in fractionated radiation regimesQ70142715
Oxygen-carrying perfluorochemical emulsion as an adjuvant to radiation therapy in miceQ70582887
Pharmacology and toxicology of sensitizers: mechanism studiesQ70590155
Metabolism induced binding of 14C-misonidazole to hypoxic cells: kinetic dependence on oxygen concentration and misonidazole concentrationQ70590161
Characteristics of the metabolism-induced binding of misonidazole to hypoxic mammalian cellsQ71681059
Initial report of the phase I trial of the hypoxic cell radiosensitizer SR-2508Q72825375
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectcancer researchQ3421914
oncologyQ162555
cell hypoxiaQ71228512
P304page(s)1103-1108
P577publication date1992-12-01
P1433published inBritish Journal of CancerQ326309
P1476titleNitroimidazole adducts as markers for tissue hypoxia: mechanistic studies in aerobic normal tissues and tumour cells
P478volume66

Reverse relations

cites work (P2860)
Q36116288Anomalous patterns of nitroimidazole binding adjacent to necrosis in human glioma xenografts: possible role of decreased oxygen consumption
Q38884487Biological characterization of novel nitroimidazole-peptide conjugates in vitro and in vivo
Q38177279Design of optimized hypoxia-activated prodrugs using pharmacokinetic/pharmacodynamic modeling.
Q92654817Electron paramagnetic resonance oximetry as a novel approach to monitor the effectiveness and quality of red blood cell transfusions
Q58692404Evaluation of Nitrobenzyl Derivatives of Camptothecin as Anti-Cancer Agents and Potential Hypoxia Targeting Prodrugs
Q36081607Evidence that hypoxia markers detect oxygen gradients in liver: pimonidazole and retrograde perfusion of rat liver
Q45071084HIF-1alpha expression follows microvascular loss in advanced murine adriamycin nephrosis
Q39002822Hypoxia: A Double-Edged Sword in Cancer Therapy
Q35928036In vivo T cell activation in lymphoid tissues is inhibited in the oxygen-poor microenvironment
Q33486397Induced hypoxia in rat pulp and periapex demonstrated by 3H-misonidazole retention
Q71993168Kinetic Analysis of Technetium-99m-Labeled Nitroimidazole (BMS-181321) as a Tracer of Myocardial Hypoxia
Q37242284Phase II study of tirapazamine, cisplatin, and etoposide and concurrent thoracic radiotherapy for limited-stage small-cell lung cancer: SWOG 0222.
Q35136222Prognostic significance of tumor oxygenation in humans.
Q33723814Radiosynthesis of [(131)I]IAZGP via nucleophilic substitution and its biological evaluation as a hypoxia marker - is specific activity a factor influencing hypoxia-mapping ability of a hypoxia marker?

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