| scholarly article | Q13442814 |
| P2093 | author name string | Svetla Stoilova-McPhie | |
| Nigel Bourne | |||
| Fernanda Laezza | |||
| Alexander Shavkunov | |||
| Anesh Prasai | |||
| Neli Panova | |||
| Ron Veselenak | |||
| P2860 | cites work | Fibroblast growth factor homologous factor 2B: association with Nav1.6 and selective colocalization at nodes of Ranvier of dorsal root axons | Q24300238 |
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| A mutation in the fibroblast growth factor 14 gene is associated with autosomal dominant cerebellar ataxia [corrected] | Q24615444 | ||
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| Crystal Structure of a Fibroblast Growth Factor Homologous Factor (FHF) Defines a Conserved Surface on FHFs for Binding and Modulation of Voltage-gated Sodium Channels | Q27655335 | ||
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| A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays | Q28145712 | ||
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| Fibroblast growth factor homologous factor 1B binds to the C terminus of the tetrodotoxin-resistant sodium channel rNav1.9a (NaN) | Q28512491 | ||
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| The penultimate rotamer library | Q29615941 | ||
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| Building a pharmacological lexicon: small molecule discovery in academia | Q33280919 | ||
| Potent, selective and cell penetrant inhibitors of SF-1 by functional ultra-high-throughput screening | Q33323340 | ||
| The cAMP-dependent protein kinase inhibitor H-89 attenuates the bioluminescence signal produced by Renilla Luciferase | Q33450656 | ||
| Apparent activity in high-throughput screening: origins of compound-dependent assay interference | Q33563613 | ||
| An ultra-high throughput cell-based screen for wee1 degradation inhibitors | Q33641125 | ||
| The IKK complex, a central regulator of NF-kappaB activation | Q33693802 | ||
| FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels | Q33705386 | ||
| Multisite phosphorylation of voltage-gated sodium channel alpha subunits from rat brain | Q33770959 | ||
| The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory. | Q33930416 | ||
| PTC124 targets genetic disorders caused by nonsense mutations | Q34003720 | ||
| Two Nedd4-binding motifs underlie modulation of sodium channel Nav1.6 by p38 MAPK. | Q34074334 | ||
| Dual-color click beetle luciferase heteroprotein fragment complementation assays. | Q34145692 | ||
| Identification of an Nav1.1 sodium channel (SCN1A) loss-of-function mutation associated with familial simple febrile seizures | Q34212724 | ||
| Molecular changes in neurons in multiple sclerosis: altered axonal expression of Nav1.2 and Nav1.6 sodium channels and Na+/Ca2+ exchanger | Q34321453 | ||
| Spinocerebellar ataxia associated with a mutation in the fibroblast growth factor 14 gene (SCA27): A new phenotype | Q34457811 | ||
| Simultaneous visualization of multiple protein interactions in living cells using multicolor fluorescence complementation analysis | Q34648424 | ||
| "JIP"ing along the axon: the complex roles of JIPs in axonal transport. | Q34725658 | ||
| Identification of novel interaction sites that determine specificity between fibroblast growth factor homologous factors and voltage-gated sodium channels | Q35085135 | ||
| Protein misfolding, aggregation, and degradation in disease | Q35168761 | ||
| Dynamic compartmentalization of the voltage-gated sodium channels in axons. | Q35575344 | ||
| Split ubiquitin as a sensor of protein interactions in vivo | Q35849562 | ||
| Nonradioactive rubidium ion efflux assay and its applications in drug discovery and development | Q36020505 | ||
| Quantification of dynamic protein complexes using Renilla luciferase fragment complementation applied to protein kinase A activities in vivo | Q36089402 | ||
| Oligomerization domain-directed reassembly of active dihydrofolate reductase from rationally designed fragments. | Q36519150 | ||
| Universal strategies in research and drug discovery based on protein-fragment complementation assays | Q36864053 | ||
| High-throughput screening assays for the identification of chemical probes | Q36885398 | ||
| Trafficking and cellular distribution of voltage-gated sodium channels. | Q36995561 | ||
| Protein kinase CK2 contributes to the organization of sodium channels in axonal membranes by regulating their interactions with ankyrin G. | Q37010706 | ||
| Novel roles for the NF-kappaB signaling pathway in regulating neuronal function | Q37083948 | ||
| Mechanism of PTC124 activity in cell-based luciferase assays of nonsense codon suppression | Q37089853 | ||
| FGF14 regulates the intrinsic excitability of cerebellar Purkinje neurons | Q37121051 | ||
| Small-molecule inhibitors of protein-protein interactions | Q37252866 | ||
| Engineering bioluminescent proteins: expanding their analytical potential | Q37440608 | ||
| Protein-protein interactions involving voltage-gated sodium channels: Post-translational regulation, intracellular trafficking and functional expression | Q37463424 | ||
| NF-kappaB dimers in the regulation of neuronal survival. | Q37553228 | ||
| Optical methods in the study of protein-protein interactions. | Q37765260 | ||
| Conformational ensembles, signal transduction and residue hot spots: application to drug discovery. | Q37784746 | ||
| Mechanisms of distribution and targeting of neuronal ion channels | Q37784747 | ||
| Signaling complexes of voltage-gated sodium and calcium channels | Q37785288 | ||
| Voltage-gated sodium channel organization in neurons: protein interactions and trafficking pathways. | Q37785312 | ||
| Identification of an axonal determinant in the C-terminus of the sodium channel Na(v)1.2. | Q39646033 | ||
| Long-term inactivation particle for voltage-gated sodium channels | Q39672545 | ||
| ERK1/2 mitogen-activated protein kinase phosphorylates sodium channel Na(v)1.7 and alters its gating properties | Q39744096 | ||
| A rescuable folding defective Nav1.1 (SCN1A) sodium channel mutant causes GEFS+: common mechanism in Nav1.1 related epilepsies? | Q39859025 | ||
| The p38 MAPK inhibitor, PD169316, inhibits transforming growth factor beta-induced Smad signaling in human ovarian cancer cells. | Q40629787 | ||
| The IkappaB kinase regulates chromatin structure during reconsolidation of conditioned fear memories. | Q41652035 | ||
| Grand challenge for ion channels: an underexploited resource for therapeutics. | Q41909123 | ||
| Oxadiazolylindazole sodium channel modulators are neuroprotective toward hippocampal neurones. | Q46064105 | ||
| Role of axonal NaV1.6 sodium channels in action potential initiation of CA1 pyramidal neurons | Q46466583 | ||
| Phosphorylation of sodium channel Na(v)1.8 by p38 mitogen-activated protein kinase increases current density in dorsal root ganglion neurons | Q46691815 | ||
| The FGF14(F145S) mutation disrupts the interaction of FGF14 with voltage-gated Na+ channels and impairs neuronal excitability | Q46918332 | ||
| High throughput ion-channel pharmacology: planar-array-based voltage clamp | Q47750406 | ||
| Co-localization of sodium channel Nav1.6 and the sodium-calcium exchanger at sites of axonal injury in the spinal cord in EAE. | Q48122449 | ||
| A targeting motif involved in sodium channel clustering at the axonal initial segment | Q48269160 | ||
| Impaired hippocampal synaptic transmission and plasticity in mice lacking fibroblast growth factor 14. | Q48316842 | ||
| Coincident enrichment of phosphorylated IkappaBalpha, activated IKK, and phosphorylated p65 in the axon initial segment of neurons. | Q48460067 | ||
| Ion channel drug discovery and research: the automated Nano-Patch-Clamp technology. | Q51588064 | ||
| Casein kinase 2 and microtubules control axon initial segment formation. | Q51899645 | ||
| New role of IKK alpha/beta phosphorylated I kappa B alpha in axon outgrowth and axon initial segment development. | Q51962634 | ||
| Novel inhibitors of cytokine-induced IkappaBalpha phosphorylation and endothelial cell adhesion molecule expression show anti-inflammatory effects in vivo | Q73596145 | ||
| A highly sensitive protein-protein interaction assay based on Gaussia luciferase | Q79351530 | ||
| Modulatory proteins can rescue a trafficking defective epileptogenic Nav1.1 Na+ channel mutant | Q81421178 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | macromolecule | Q178593 |
| protein-protein interaction | Q896177 | ||
| bioluminescence | Q179924 | ||
| P304 | page(s) | 148-160 | |
| P577 | publication date | 2012-02-24 | |
| P1433 | published in | Assay and Drug Development Technologies | Q15767279 |
| P1476 | title | Bioluminescence methodology for the detection of protein-protein interactions within the voltage-gated sodium channel macromolecular complex | |
| P478 | volume | 10 |
| Q58695932 | Biophysical validation of serotonin 5-HT2A and 5-HT2C receptor interaction |
| Q36913792 | CK2 activity is required for the interaction of FGF14 with voltage-gated sodium channels and neuronal excitability |
| Q50323466 | Conditional knockout of Fgf13 in murine hearts increases arrhythmia susceptibility and reveals novel ion channel modulatory roles |
| Q30465622 | Control of neuronal ion channel function by glycogen synthase kinase-3: new prospective for an old kinase |
| Q33807901 | Decoy peptide targeted to Toll-IL-1R domain inhibits LPS and TLR4-active metabolite morphine-3 glucuronide sensitization of sensory neurons. |
| Q38674566 | Fibroblast Growth Factor 14 Modulates the Neurogenesis of Granule Neurons in the Adult Dentate Gyrus |
| Q48186245 | Functional Modulation of Voltage-Gated Sodium Channels by a FGF14-Based Peptidomimetic. |
| Q41501850 | Genetic deletion of fibroblast growth factor 14 recapitulates phenotypic alterations underlying cognitive impairment associated with schizophrenia. |
| Q91292048 | High-throughput screening against protein:protein interaction interfaces reveals anti-cancer therapeutics as potent modulators of the voltage-gated Na+ channel complex |
| Q36987685 | Identification of Amino Acid Residues in Fibroblast Growth Factor 14 (FGF14) Required for Structure-Function Interactions with Voltage-gated Sodium Channel Nav1.6. |
| Q35557270 | Identifying a kinase network regulating FGF14:Nav1.6 complex assembly using split-luciferase complementation |
| Q28392635 | Integrative biological analysis for neuropsychopharmacology |
| Q33578795 | Intracellular Fibroblast Growth Factor 14: Emerging Risk Factor for Brain Disorders. |
| Q39567009 | Modulation of the FGF14:FGF14 homodimer interaction through short peptide fragments. |
| Q38776236 | PPARgamma agonists rescue increased phosphorylation of FGF14 at S226 in the Tg2576 mouse model of Alzheimer's disease. |
| Q42055747 | Parallel fiber to Purkinje cell synaptic impairment in a mouse model of spinocerebellar ataxia type 27. |
| Q41717369 | Protein-Protein Interactions as New Targets for Ion Channel Drug Discovery. |
| Q35583345 | Quantitative proteomics reveals protein-protein interactions with fibroblast growth factor 12 as a component of the voltage-gated sodium channel 1.2 (nav1.2) macromolecular complex in Mammalian brain. |
| Q38227133 | Split-luciferase complementary assay: applications, recent developments, and future perspectives |
| Q34467171 | The Fibroblast Growth Factor signaling pathway |
| Q39756006 | The Nav1.2 channel is regulated by GSK3. |
| Q34703974 | The fibroblast growth factor 14·voltage-gated sodium channel complex is a new target of glycogen synthase kinase 3 (GSK3). |
| Q89459059 | Voltage-gated sodium currents in cerebellar Purkinje neurons: functional and molecular diversity |
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