PBRM1 Regulates the Expression of Genes Involved in Metabolism and Cell Adhesion in Renal Clear Cell Carcinoma

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PBRM1 Regulates the Expression of Genes Involved in Metabolism and Cell Adhesion in Renal Clear Cell Carcinoma is …
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scholarly articleQ13442814

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P819ADS bibcode2016PLoSO..1153718C
P356DOI10.1371/JOURNAL.PONE.0153718
P932PMC publication ID4839679
P698PubMed publication ID27100670

P50authorEmily C DykhuizenQ57943571
P2093author name stringMatthew J Schipma
Christina R Ferreira
Elizabeth G Porter
Jane C Stewart
Basudev Chowdhury
P2860cites workThe spectrum of SWI/SNF mutations, ubiquitous in human cancersQ21090801
Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinomaQ24337664
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profilesQ24536351
Abnormal cholesterol metabolism in renal clear cell carcinomaQ69449106
Adhesion of metastatic and non-metastatic carcinoma cells to glass surfacesQ70796296
Cholesterol accumulation in heterotransplanted renal cell cancerQ71691167
Analysis of free and esterified sterols in fats and oils by flash chromatography, gas chromatography and electrospray tandem mass spectrometryQ77406469
Renal cell carcinomaQ82656838
Mechanisms of motility in metastasizing cellsQ37749124
Dual inhibition of PI3-kinase and mTOR in renal cell carcinomaQ38069238
Ambient ionisation mass spectrometry for lipid profiling and structural analysis of mammalian oocytes, preimplantation embryos and stem cellsQ38374968
Integrative bioinformatics analysis reveals new prognostic biomarkers of clear cell renal cell carcinomaQ38964441
Loss of PBRM1 expression is associated with renal cell carcinoma progressionQ39285387
Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxiaQ39698671
SWI/SNF regulates the cellular response to hypoxia.Q39903276
Kidney cancer, version 3.2015.Q41407499
The FoxO-BNIP3 axis exerts a unique regulation of mTORC1 and cell survival under energy stress.Q42268781
Integrins and laminins in human renal carcinoma cells and tumors grown in nude mice.Q42495884
Targeted exome sequencing in clear cell renal cell carcinoma tumors suggests aberrant chromatin regulation as a crucial step in ccRCC development.Q45880509
High throughput quantification of cholesterol and cholesteryl ester by electrospray ionization tandem mass spectrometry (ESI-MS/MS).Q46928125
COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in CancerQ24608391
Dual roles of myocardin-related transcription factors in epithelial mesenchymal transition via slug induction and actin remodelingQ24684909
A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATIONQ25939000
Molecular mechanisms of epithelial-mesenchymal transitionQ27013743
Comprehensive molecular characterization of clear cell renal cell carcinomaQ27852374
Integrated molecular analysis of clear-cell renal cell carcinomaQ27852382
Epithelial-mesenchymal transitions in development and diseaseQ27860630
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2Q29547403
Complex networks orchestrate epithelial-mesenchymal transitionsQ29547478
HTSeq--a Python framework to work with high-throughput sequencing dataQ29614489
STAR: ultrafast universal RNA-seq alignerQ29615052
Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genesQ29615757
In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitroQ29617927
Cell adhesion: integrating cytoskeletal dynamics and cellular tensionQ29618066
Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICEQ29619356
Arp2/3 complex inhibitors adversely affect actin cytoskeleton remodeling in the cultured murine kidney collecting duct M-1 cellsQ30558614
Isotropic actomyosin dynamics promote organization of the apical cell cortex in epithelial cellsQ30591643
Molecular genetics of clear-cell renal cell carcinomaQ33729097
Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma.Q33863055
BAF180 is a critical regulator of p21 induction and a tumor suppressor mutated in breast cancerQ34042035
Fructose-1,6-bisphosphatase opposes renal carcinoma progressionQ34173576
BAP1 loss defines a new class of renal cell carcinomaQ34280223
Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy.Q34342958
VHL, the story of a tumour suppressor geneQ34455226
Increased expression of the very low-density lipoprotein receptor mediates lipid accumulation in clear-cell renal cell carcinomaQ34489747
FoxOs enforce a progression checkpoint to constrain mTORC1-activated renal tumorigenesisQ34504786
Cell-matrix adhesions in 3DQ35317048
Genetic and functional studies implicate HIF1α as a 14q kidney cancer suppressor geneQ35452783
Actin cytoskeleton regulation of epithelial mesenchymal transition in metastatic cancer cellsQ35574445
Dynamic actin remodeling during epithelial-mesenchymal transition depends on increased moesin expression.Q35612241
GENECODIS: a web-based tool for finding significant concurrent annotations in gene listsQ35724720
GeneCodis3: a non-redundant and modular enrichment analysis tool for functional genomicsQ36088447
The VHL/HIF axis in clear cell renal carcinomaQ36872295
GeneCodis: interpreting gene lists through enrichment analysis and integration of diverse biological informationQ37245619
BRG1 and BRM chromatin-remodeling complexes regulate the hypoxia response by acting as coactivators for a subset of hypoxia-inducible transcription factor target genesQ37264934
A study exploring critical pathways in clear cell renal cell carcinomaQ37388562
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
DESeq2Q113018293
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectcell adhesionQ187640
clear cell carcinomaQ18556242
renal clear cell carcinomaQ18556340
P304page(s)e0153718
P577publication date2016-04-21
P1433published inPLOS OneQ564954
P1476titlePBRM1 Regulates the Expression of Genes Involved in Metabolism and Cell Adhesion in Renal Clear Cell Carcinoma
P478volume11

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cites work (P2860)
Q89863068A novel EZH2 inhibitor induces synthetic lethality and apoptosis in PBRM1-deficient cancer cells
Q28073283Choosing the right cell line for renal cell cancer research
Q37627446Context-dependent role for chromatin remodeling component PBRM1/BAF180 in clear cell renal cell carcinoma.
Q88985337Epigenetics in renal cell cancer: mechanisms and clinical applications
Q41574276Epigenome Aberrations: Emerging Driving Factors of the Clear Cell Renal Cell Carcinoma
Q98513545HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice
Q41779657Inactivation of the PBRM1 tumor suppressor gene amplifies the HIF-response in VHL-/- clear cell renal carcinoma
Q38722947Individual Bromodomains of Polybromo-1 Contribute to Chromatin Association and Tumor Suppression in Clear Cell Renal Carcinoma
Q92854022New Insights into the Role of Polybromo-1 in Prostate Cancer
Q64085735PBRM1 Regulates Stress Response in Epithelial Cells
Q89479726PBRM1 bromodomains variably influence nucleosome interactions and cellular function
Q41532653PBRM1 regulates proliferation and the cell cycle in renal cell carcinoma through a chemokine/chemokine receptor interaction pathway
Q55300818Profiling of epidermal lipids in a mouse model of dermatitis: Identification of potential biomarkers.
Q92154621Prognostic and Predictive Value of PBRM1 in Clear Cell Renal Cell Carcinoma
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Q93128856Transcriptional Response of White Adipose Tissue to Withdrawal of Vitamin B3

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