Prognostic and clinicopathological significance of Gankyrin overexpression in cancers: evidence from a meta-analysis

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Prognostic and clinicopathological significance of Gankyrin overexpression in cancers: evidence from a meta-analysis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2147/OTT.S101687
P932PMC publication ID4831594
P698PubMed publication ID27110125

P2093author name stringYuan Zhang
Xiaotong Zhao
Fangzhou Liu
Peihua Li
P2860cites workReduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomasQ22010990
Novel insights into the INK4-CDK4/6-Rb pathway: counter action of gankyrin against INK4 proteins regulates the CDK4-mediated phosphorylation of RbQ24292483
Oncoprotein p28 GANK binds to RelA and retains NF-kappaB in the cytoplasm through nuclear exportQ24301532
The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53Q24307855
cDNA cloning and functional analysis of p28 (Nas6p) and p40.5 (Nas7p), two novel regulatory subunits of the 26S proteasomeQ24336549
Bias in meta-analysis detected by a simple, graphical testQ24685585
The crystal structure of gankyrin, an oncoprotein found in complexes with cyclin-dependent kinase 4, a 19 S proteasomal ATPase regulator, and the tumor suppressors Rb and p53Q27642398
Measuring inconsistency in meta-analysesQ27860655
Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analysesQ28131633
Practical methods for incorporating summary time-to-event data into meta-analysisQ28131754
Quantitative synthesis in systematic reviewsQ29614894
Gankyrin promotes tumor growth and metastasis through activation of IL-6/STAT3 signaling in human cholangiocarcinoma.Q53090136
[Association of gankyrin protein expression in human colorectal cancer with postoperative prognosis].Q53642759
Role of a novel oncogenic protein, gankyrin, in hepatocyte proliferationQ54753276
Gankyrin: a new oncoprotein and regulator of pRb and p53Q61948837
[P28GANK is a novel marker for prognosis and therapeutic target in gastric cancer]Q95624658
Gradually elevated expression of Gankyrin during human hepatocarcinogenesis and its clinicopathological significanceQ33851157
Gankyrin is a predictive and oncogenic factor in well-differentiated and dedifferentiated liposarcoma.Q34619226
Gankyrin is frequently overexpressed in cervical high grade disease and is associated with cervical carcinogenesis and metastasisQ35153915
Up-regulated oncoprotein P28GANK correlates with proliferation and poor prognosis of human gliomaQ36235734
Clinicopathologic features and prognostic implications of Gankyrin protein expression in non-small cell lung cancerQ39134905
Gankyrin activates IL-8 to promote hepatic metastasis of colorectal cancerQ39168162
Gankyrin is frequently overexpressed in breast cancer and is associated with ErbB2 expressionQ39218576
Gankyrin plays an essential role in estrogen-driven and GPR30-mediated endometrial carcinoma cell proliferation via the PTEN/PI3K/AKT signaling pathwayQ39246928
p28GANK overexpression accelerates hepatocellular carcinoma invasiveness and metastasis via phosphoinositol 3-kinase/AKT/hypoxia-inducible factor-1α pathwaysQ39604806
Gankyrin promotes the proliferation of human pancreatic cancerQ39702569
Association of gankyrin protein expression with early clinical stages and insulin-like growth factor-binding protein 5 expression in human hepatocellular carcinomaQ40030453
Gankyrin oncoprotein overexpression as a critical factor for tumor growth in human esophageal squamous cell carcinoma and its clinical significanceQ40068246
Solution structure of the human oncogenic protein gankyrin containing seven ankyrin repeats and analysis of its structure--function relationship.Q45067243
X-ray structure of human gankyrin, the product of a gene linked to hepatocellular carcinoma.Q48007385
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectoverexpressionQ61643320
P304page(s)1961-1968
P577publication date2016-04-04
P1433published inOncoTargets and TherapyQ7092081
P1476titlePrognostic and clinicopathological significance of Gankyrin overexpression in cancers: evidence from a meta-analysis
P478volume9

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cites work (P2860)
Q39319386Gankyrin as a potential therapeutic target for cancer
Q47661011Gankyrin: a novel promising therapeutic target for hepatocellular carcinoma