| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1047836639 |
| P356 | DOI | 10.1038/71600 |
| P3181 | OpenCitations bibliographic resource ID | 2492961 |
| P698 | PubMed publication ID | 10613832 |
| P5875 | ResearchGate publication ID | 51359641 |
| P2093 | author name string | K Itoh | |
| J Fujita | |||
| K Nonoguchi | |||
| T Kido | |||
| R J Mayer | |||
| S Dawson | |||
| T Nagao | |||
| S Arii | |||
| H Higashitsuji | |||
| P2860 | cites work | HEC binds to the seventh regulatory subunit of the 26 S proteasome and modulates the proteolysis of mitotic cyclins | Q24311923 |
| The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53 | Q24317677 | ||
| A retinoblastoma-binding protein that affects cell-cycle control and confers transforming ability | Q24322385 | ||
| cDNA cloning and functional analysis of p28 (Nas6p) and p40.5 (Nas7p), two novel regulatory subunits of the 26S proteasome | Q24336549 | ||
| The retinoblastoma protein and cell cycle control | Q27860722 | ||
| Induction of tissue inhibitor of metalloproteinase 3 gene expression during in vitro decidualization of human endometrial stromal cells | Q28291370 | ||
| Induction of tissue inhibitor of metalloproteinase 3 gene expression during in vitro decidualization of human endometrial stromal cells | Q29400659 | ||
| The human papillomavirus E7 oncoprotein functionally interacts with the S4 subunit of the 26 S proteasome | Q33292204 | ||
| The ubiquitin-proteasome pathway in cancer | Q36295120 | ||
| Intranuclear localization of human papillomavirus 16 E7 during transformation and preferential binding of E7 to the Rb family member p130 | Q36388622 | ||
| Role of the Rb/E2F pathway in cell growth control | Q41640467 | ||
| Role of E2F in cell cycle control and cancer | Q41747104 | ||
| The 26S-proteasome: regulation and substrate recognition | Q42062653 | ||
| Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa | Q46754150 | ||
| Mutational hot spot in the p53 gene in human hepatocellular carcinomas | Q53499208 | ||
| The ubiquitin-mediated proteolytic system: involvement of molecular chaperones, degradation of oncoproteins, and activation of transcriptional regulators | Q71574287 | ||
| Discrimination between ubiquitin-dependent and ubiquitin-independent proteolytic pathways by the 26S proteasome subunit 5a | Q77816630 | ||
| The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation | Q77911981 | ||
| High frequency of p16INK4A gene alterations in hepatocellular carcinoma | Q78171350 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | retinoblastoma | Q500695 |
| positive regulation of proteasomal ubiquitin-dependent protein catabolic process | Q14864932 | ||
| Proteasome 26S subunit, non-ATPase 10 | Q21107941 | ||
| overexpression | Q61643320 | ||
| P304 | page(s) | 96-9 | |
| P577 | publication date | 2000-01-01 | |
| P1433 | published in | Nature Medicine | Q1633234 |
| P1476 | title | Reduced stability of retinoblastoma protein by gankyrin, an oncogenic ankyrin-repeat protein overexpressed in hepatomas | |
| P478 | volume | 6 |
| Q39483038 | A 19S proteasomal subunit cooperates with an ERK MAPK-regulated degron to regulate accumulation of Fra-1 in tumour cells. |
| Q36301276 | A Novel Retinoblastoma Protein (RB) E3 Ubiquitin Ligase (NRBE3) Promotes RB Degradation and Is Transcriptionally Regulated by E2F1 Transcription Factor |
| Q24305959 | A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells |
| Q47280258 | A novel diagnostic marker, p28GANK distinguishes hepatocellular carcinoma from potential mimics |
| Q34156179 | A novel protein overexpressed in hepatoma accelerates export of NF-kappa B from the nucleus and inhibits p53-dependent apoptosis |
| Q28072560 | APC/C and retinoblastoma interaction: cross-talk of retinoblastoma protein with the ubiquitin proteasome pathway |
| Q79767255 | ARF promotes accumulation of retinoblastoma protein through inhibition of MDM2 |
| Q35094511 | Aberrant ubiquitin-mediated proteolysis of cell cycle regulatory proteins and oncogenesis |
| Q48345586 | Acquired expression of transcriptionally active p73 in hepatocellular carcinoma cells |
| Q38345445 | Activation of the CKI-CDK-Rb-E2F pathway in full genome hepatitis C virus-expressing cells |
| Q39415233 | Adriamycin enhances proteasome-mediated generation of the proapoptotic processed form of MAGE-A4 in hepatoma cells |
| Q37212693 | Analysis of expression profiles of MAGE-A antigens in oral squamous cell carcinoma cell lines |
| Q36938591 | Analysis of the mechanisms mediating tumor-specific changes in gene expression in human liver tumors |
| Q40762889 | Androgen stimulated cellular proliferation in the human prostate cancer cell line LNCaP is associated with reduced retinoblastoma protein expression |
| Q28573028 | Apg-2 has a chaperone-like activity similar to Hsp110 and is overexpressed in hepatocellular carcinomas |
| Q52595227 | Arctigenin Inhibits Liver Cancer Tumorigenesis by Inhibiting Gankyrin Expression via C/EBPα and PPARα. |
| Q36200349 | Assembly manual for the proteasome regulatory particle: the first draft |
| Q24316277 | Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones |
| Q33988314 | Assembly, structure, and function of the 26S proteasome. |
| Q45343776 | Association of gankyrin and stemness factor expression in human colorectal cancer |
| Q40030453 | Association of gankyrin protein expression with early clinical stages and insulin-like growth factor-binding protein 5 expression in human hepatocellular carcinoma |
| Q35819901 | Biological functions of melanoma-associated antigens |
| Q37225340 | Cellular mechanisms of tumour suppression by the retinoblastoma gene. |
| Q52087746 | Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling. |
| Q38698061 | Construction of a recombinant lentivirus-mediated shRNA expression vector targeting the human PSMD10 gene and validation of RNAi efficiency in RPMI‑8226 multiple myeloma cells |
| Q34280071 | Coordinated expression of cyclin-dependent kinase-4 and its regulators in human oral tumors |
| Q27642447 | Crystal Structure of the Homolog of the Oncoprotein Gankyrin, an Interactor of Rb and CDK4/6 |
| Q39606496 | Degradation of the retinoblastoma tumor suppressor by the human papillomavirus type 16 E7 oncoprotein is important for functional inactivation and is separable from proteasomal degradation of E7. |
| Q38994050 | Deregulation of RB1 expression by loss of imprinting in human hepatocellular carcinoma. |
| Q37485899 | Destabilization of Rb by human papillomavirus E7 is cell cycle dependent: E2-25K is involved in the proteolysis |
| Q42999479 | Dietary fat/cholesterol-sensitive PKCβ-RB signaling: Potential role in NASH/HCC axis |
| Q39043145 | Discovery of multiple interacting partners of gankyrin, a proteasomal chaperone and an oncoprotein--evidence for a common hot spot site at the interface and its functional relevance. |
| Q34049279 | Disruption of G1-phase phospholipid turnover by inhibition of Ca2+-independent phospholipase A2 induces a p53-dependent cell-cycle arrest in G1 phase |
| Q41982097 | Dissection of protein-protein interaction and CDK4 inhibition in the oncogenic versus tumor suppressing functions of gankyrin and P16. |
| Q34226063 | Do VHL and HIF-1 mirror p53 and Mdm-2? Degradation-transactivation loops of oncoproteins and tumor suppressors |
| Q60920505 | Dysregulation of Nrf2 in Hepatocellular Carcinoma: Role in Cancer Progression and Chemoresistance |
| Q34557983 | Effects of ligand binding on the mechanical properties of ankyrin repeat protein gankyrin |
| Q41895897 | Elimination of C/EBPalpha through the ubiquitin-proteasome system promotes the development of liver cancer in mice |
| Q33278013 | Enhanced deacetylation of p53 by the anti-apoptotic protein HSCO in association with histone deacetylase 1. |
| Q33300364 | Evidence that proteasome-dependent degradation of the retinoblastoma protein in cells lacking A-type lamins occurs independently of gankyrin and MDM2. |
| Q38991575 | Expression of the oncoprotein gankyrin and phosphorylated retinoblastoma protein in human testis and testicular germ cell tumor |
| Q42064032 | Fission yeast Dss1 associates with the proteasome and is required for efficient ubiquitin-dependent proteolysis |
| Q38347016 | Functional and physical interaction of the human ARF tumor suppressor with Tat-binding protein-1. |
| Q37184865 | Functional characterization of human oncoprotein gankyrin in Zebrafish |
| Q98291007 | Gankyrin Oncoprotein: Structure, Function, and Involvement in Cancer |
| Q36346927 | Gankyrin drives malignant transformation of chronic liver damage-mediated fibrosis via the Rac1/JNK pathway |
| Q38835733 | Gankyrin facilitates follicle-stimulating hormone-driven ovarian cancer cell proliferation through the PI3K/AKT/HIF-1α/cyclin D1 pathway |
| Q34389801 | Gankyrin gene deletion followed by proteomic analysis: insight into the roles of Gankyrin in tumorigenesis and metastasis |
| Q36863127 | Gankyrin has an antioxidative role through the feedback regulation of Nrf2 in hepatocellular carcinoma. |
| Q42288668 | Gankyrin induces STAT3 activation in tumor microenvironment and sorafenib resistance in hepatocellular carcinoma |
| Q28214769 | Gankyrin is an ankyrin-repeat oncoprotein that interacts with CDK4 kinase and the S6 ATPase of the 26 S proteasome |
| Q39218576 | Gankyrin is frequently overexpressed in breast cancer and is associated with ErbB2 expression |
| Q40068246 | Gankyrin oncoprotein overexpression as a critical factor for tumor growth in human esophageal squamous cell carcinoma and its clinical significance |
| Q34028736 | Gankyrin plays an essential role in Ras-induced tumorigenesis through regulation of the RhoA/ROCK pathway in mammalian cells |
| Q39298025 | Gankyrin promotes breast cancer cell metastasis by regulating Rac1 activity |
| Q37701508 | Gankyrin promotes epithelial-mesenchymal transition and metastasis in NSCLC through forming a closed circle with IL-6/ STAT3 and TGF-β/SMAD3 signaling pathway |
| Q38698888 | Gankyrin promotes the proliferation of gastric cancer and is associated with chemosensitivity |
| Q53090136 | Gankyrin promotes tumor growth and metastasis through activation of IL-6/STAT3 signaling in human cholangiocarcinoma. |
| Q38714564 | Gankyrin regulates cell signaling network |
| Q37697139 | Gankyrin sustains PI3K/GSK-3β/β-catenin signal activation and promotes colorectal cancer aggressiveness and progression |
| Q39511329 | Gankyrin-mediated dedifferentiation facilitates the tumorigenicity of rat hepatocytes and hepatoma cells |
| Q47661011 | Gankyrin: a novel promising therapeutic target for hepatocellular carcinoma |
| Q43159668 | Gene and protein expressions of p28GANK in rat with liver regeneration. |
| Q35110344 | Generation of a Retinoblastoma (Rb)1-inducible dominant-negative (DN) mouse model |
| Q34611410 | Genetic mechanisms of hepatocarcinogenesis |
| Q36519006 | Genetics of hepatocellular tumors. |
| Q33851157 | Gradually elevated expression of Gankyrin during human hepatocarcinogenesis and its clinicopathological significance |
| Q27485880 | Hepatitis C Virus Induces E6AP-Dependent Degradation of the Retinoblastoma Protein |
| Q38083250 | Human hepatocyte carcinogenesis (review). |
| Q36098917 | Human papillomavirus type 16 E7 oncoprotein associates with the cullin 2 ubiquitin ligase complex, which contributes to degradation of the retinoblastoma tumor suppressor |
| Q35036585 | Human papillomavirus-induced carcinogenesis and the ubiquitin-proteasome system |
| Q24317434 | Identification and functional analysis of a novel cyclin e/cdk2 substrate ankrd17 |
| Q38717741 | Identification of proteasomal catalytic subunit PSMA6 as a therapeutic target for lung cancer. |
| Q34159639 | Inhibition of aldose reductase prevents growth factor-induced G1-S phase transition through the AKT/phosphoinositide 3-kinase/E2F-1 pathway in human colon cancer cells |
| Q28068512 | Inhibition of apoptosis by oncogenic hepatitis B virus X protein: Implications for the treatment of hepatocellular carcinoma |
| Q42184152 | Interleukin-1β/Iinterleukin-1 receptor-associated kinase 1 inflammatory signaling contributes to persistent Gankyrin activation during hepatocarcinogenesis |
| Q35586439 | Intracellular signaling and hepatocellular carcinoma |
| Q37369888 | LBH589 Inhibits proliferation and metastasis of hepatocellular carcinoma via inhibition of gankyrin/STAT3/Akt pathway |
| Q37889223 | Liver development and cancer formation in zebrafish. |
| Q33785451 | Loss of runt-related transcription factor 3 expression leads hepatocellular carcinoma cells to escape apoptosis |
| Q24338637 | MAGE-A4 interacts with the liver oncoprotein gankyrin and suppresses its tumorigenic activity |
| Q38111684 | Mechanisms of proteasome inhibitor-induced cytotoxicity in malignant glioma |
| Q27001727 | Micro(RNA)managing endoplasmic reticulum stress |
| Q37361575 | MicroRNA involvement in hepatocellular carcinoma |
| Q35095232 | Modulation of the unfolded protein response is the core of microRNA-122-involved sensitivity to chemotherapy in hepatocellular carcinoma |
| Q78357688 | Molecular pathogenesis of human hepatocellular carcinoma |
| Q56915453 | Mutational analyses of RB and BRCA2 as candidate tumour suppressor genes in parathyroid carcinoma |
| Q24291362 | Negative regulation of G(1)/S transition by the candidate bladder tumour suppressor gene DBCCR1 |
| Q36519041 | New therapies for hepatocellular carcinoma. |
| Q35237526 | Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway. |
| Q24301532 | Oncoprotein p28 GANK binds to RelA and retains NF-kappaB in the cytoplasm through nuclear export |
| Q34144126 | Overexpression of p28/gankyrin in human hepatocellular carcinoma and its clinical significance |
| Q34186659 | PAX8 promotes tumor cell growth by transcriptionally regulating E2F1 and stabilizing RB protein |
| Q90111166 | POTEE promotes colorectal carcinoma progression via activating the Rac1/Cdc42 pathway |
| Q37141742 | PSMD10/gankyrin induces autophagy to promote tumor progression through cytoplasmic interaction with ATG7 and nuclear transactivation of ATG7 expression |
| Q28272678 | Prevention of hepatocellular carcinoma: potential targets, experimental models, and clinical challenges |
| Q35997896 | Prognostic and clinicopathological significance of Gankyrin overexpression in cancers: evidence from a meta-analysis |
| Q36580569 | Purification, crystallization and preliminary X-ray diffraction analysis of the non-ATPase subunit Nas6 in complex with the ATPase subunit Rpt3 of the 26S proteasome from Saccharomyces cerevisiae |
| Q50970430 | RNA Binding Protein CUGBP1 Inhibits Liver Cancer in a Phosphorylation-Dependent Manner. |
| Q53391613 | Recurrent allelic deletions at mouse chromosomes 4 and 14 in Myc-induced liver tumors. |
| Q35147982 | Regulation of CDK4 |
| Q37085853 | Regulation of the retinoblastoma proteins by the human herpesviruses. |
| Q37880852 | Regulatory mechanisms of tumor suppressor P16(INK4A) and their relevance to cancer |
| Q42548703 | Resurfaced shape complementary proteins that selectively bind the oncoprotein gankyrin |
| Q28272252 | Retinoblastoma protein modulates gankyrin-MDM2 in regulation of p53 stability and chemosensitivity in cancer cells |
| Q84292343 | Roles of heat shock factor 1 and 2 in response to proteasome inhibition: consequence on p53 stability |
| Q36945870 | Scratching the Surface: Resurfacing Proteins to Endow New Properties and Function |
| Q43574623 | Sequential changes in hepatocarcinogenesis induced by diethylnitrosamine plus thioacetamide in Fischer 344 rats: induction of gankyrin expression in liver fibrosis, pRB degradation in cirrhosis, and methylation of p16(INK4A) exon 1 in hepatocellular |
| Q35019588 | Spectrum of molecular changes during hepatocarcinogenesis induced by DEN and other chemicals in Fischer 344 male rats. |
| Q44490652 | Spectrum of molecular changes during hepatocarcinogenesis induced by DEN and other chemicals in Fisher 344 male rats [Mechanisms of Ageing and Development 123 (2002) 1665-1680]. |
| Q38178032 | The Complex Relationship between Liver Cancer and the Cell Cycle: A Story of Multiple Regulations. |
| Q90429861 | The Oncoprotein Gankyrin/PSMD10 as a Target of Cancer Therapy |
| Q26777419 | The Role of Autophagy in Hepatocellular Carcinoma |
| Q37849976 | The biology of cancer testis antigens: putative function, regulation and therapeutic potential |
| Q27642398 | The crystal structure of gankyrin, an oncoprotein found in complexes with cyclin-dependent kinase 4, a 19 S proteasomal ATPase regulator, and the tumor suppressors Rb and p53 |
| Q36981804 | The expanding role of fish models in understanding non-alcoholic fatty liver disease |
| Q27003050 | The genetic and epigenetic alterations in human hepatocellular carcinoma: a recent update |
| Q36647336 | The hepatic transcriptome in human liver disease |
| Q38162804 | The impact of hypoxia in hepatocellular carcinoma metastasis. |
| Q83291299 | The melanoma-associated antigen-A3, -A4 genes: relation to the risk and clinicopathological parameters in breast cancer patients |
| Q34186331 | The meteoric rise of regulated intracellular proteolysis |
| Q24307855 | The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53 |
| Q41819994 | The oncoprotein gankyrin promotes the development of colitis-associated cancer through activation of STAT3. |
| Q35348787 | The oncoprotein p28GANK establishes a positive feedback loop in β-catenin signaling |
| Q46920600 | The role of p28GANK in rat oval cells activation and proliferation |
| Q37706211 | The transcription levels and prognostic values of seven proteasome alpha subunits in human cancers |
| Q24292709 | The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction |
| Q38069898 | Therapeutic targeting of cancer cell cycle using proteasome inhibitors |
| Q47245509 | Unexpected Lower Expression of Oncoprotein Gankyrin in Drug Resistant ABCG2 Overexpressing Breast Cancer Cell Lines |
| Q36235734 | Up-regulated oncoprotein P28GANK correlates with proliferation and poor prognosis of human glioma |
| Q41615123 | Upregulation of PSMD10 caused by the JMJD2A histone demethylase |
| Q34568619 | Viral hepatitis and liver cancer: the case of hepatitis C. |
| Q35571368 | When protein destruction runs amok, malignancy is on the loose |
| Q36232005 | YAP is a critical oncogene in human cholangiocarcinoma |
| Q57068280 | miR-214 regulates papillary thyroid carcinoma cell proliferation and metastasis by targeting PSMD10 |
| Q53554846 | p21(Waf1/Cip1/Sdi1) mediates retinoblastoma protein degradation. |
| Q42834062 | p28GANK inhibits endoplasmic reticulum stress-induced cell death via enhancement of the endoplasmic reticulum adaptive capacity |
| Q39604806 | p28GANK overexpression accelerates hepatocellular carcinoma invasiveness and metastasis via phosphoinositol 3-kinase/AKT/hypoxia-inducible factor-1α pathways |
| Q92382728 | p28GANK overexpression is associated with chemotherapy resistance and poor prognosis in ovarian cancer |
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