Human innate B cells: a link between host defense and autoimmunity?

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Human innate B cells: a link between host defense and autoimmunity? is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1007/S00281-004-0188-9
P932PMC publication ID1431976
P698PubMed publication ID15633016
P5875ResearchGate publication ID8098010

P50authorIñaki SanzQ91392897
P2093author name stringJennifer Anolik
Amedeo Cappione
Eric C B Milner
P2860cites workRP105 is associated with MD-1 and transmits an activation signal in human B cellsQ22003903
TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune diseaseQ22254041
Human CD14 mediates recognition and phagocytosis of apoptotic cellsQ24336506
A critical role of natural immunoglobulin M in immediate defense against systemic bacterial infectionQ24646925
Human immunoglobulin M memory B cells controlling Streptococcus pneumoniae infections are generated in the spleenQ24673510
BLyS and B cell autoimmunityQ28212304
A composite picture of TcR alpha/beta(+) CD4(-)CD8(-) T Cells (alpha/beta-DNTCs) in humans with autoimmune lymphoproliferative syndromeQ28215936
Lipopolysaccharides from Campylobacter jejuni O:41 strains associated with Guillain-Barré syndrome exhibit mimicry of GM1 gangliosideQ28368289
Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient miceQ28587370
Regulation of B-lymphocyte negative and positive selection by tyrosine phosphatase CD45Q28592092
CD1-restricted T cell recognition of microbial lipoglycan antigensQ28610594
Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptorsQ29615065
Delineation of the human systemic lupus erythematosus anti-Smith antibody response using phage-display combinatorial librariesQ30976820
Correlation of 9G4 idiotope with disease activity in patients with systemic lupus erythematosusQ31956873
An inherited disorder of lymphocyte apoptosis: the autoimmune lymphoproliferative syndromeQ33328425
CD1, tuberculosis, and the evolution of major histocompatibility complex moleculesQ33869275
Structural basis for autoantibody recognition of phosphatidylserine-beta 2 glycoprotein I and apoptotic cellsQ33950104
B-cell subsets and the mature preimmune repertoire. Marginal zone and B1 B cells as part of a "natural immune memory".Q33996226
Lipopolysaccharide-activated B cells down-regulate Th1 immunity and prevent autoimmune diabetes in nonobese diabetic miceQ34083166
T lymphocyte recognition of human group 1 CD1 molecules: implications for innate and acquired immunityQ34123030
CD1d-restricted mouse V alpha 14 and human V alpha 24 T cells: lymphocytes of innate immunityQ34123048
Evidence for involvement of a hydrophobic patch in framework region 1 of human V4-34-encoded Igs in recognition of the red blood cell I antigenQ34150551
B cells regulate autoimmunity by provision of IL-10.Q34150590
Peripheral development of B cells in mouse and man.Q34298533
Surface immunoglobulin-mediated B-cell activation in the absence of detectable elevations in intracellular ionized calcium: a model for T-cell-independent B-cell activationQ34301661
An etiopathogenic role for the type I IFN system in SLE.Q34319930
Analysis of somatic mutation in five B cell subsets of human tonsilQ34328629
CD1-specific T cells in microbial immunityQ34332693
Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- alpha/beta T cells demonstrates preferential use of several V beta genes and an invariant TCR alpha chainQ34356372
Nucleotide sequence analysis of the V regions of two IgM cold agglutinins. Evidence that the VH4-21 gene segment is responsible for the major cross-reactive idiotypeQ34581434
CD40-CD40L independent Ig gene hypermutation suggests a second B cell diversification pathway in humansQ34651496
Toll-like receptors and activation of autoreactive B cellsQ34984412
Accelerated development of IgG autoantibodies and autoimmune disease in the absence of secreted IgM.Q35010060
Role of B cells in maintaining helper T-cell memoryQ35212655
The central role of dendritic cells and interferon-alpha in SLE.Q35213874
The regulation of lupus-associated autoantibodies: immunoglobulin transgenic modelsQ35589858
Positive selection focuses the VH12 B-cell repertoire towards a single B1 specificity with survival functionQ35666663
Development and selection of marginal zone B cellsQ35666707
Regulation of inherently autoreactive VH4-34 B cells in the maintenance of human B cell toleranceQ36041818
The human VH repertoire: a restricted set of VH genes may be the target of immune regulationQ36196150
Induction of a cationic shift in IgG anti-DNA autoantibodies. Role of T helper cells with classical and novel phenotypes in three murine models of lupus nephritisQ36352584
CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper functionQ36368291
Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis.Q36369797
A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupusQ36369955
Subsets of transgenic T cells that recognize CD1 induce or prevent murine lupus: role of cytokinesQ36400325
CD1d-mediated recognition of an alpha-galactosylceramide by natural killer T cells is highly conserved through mammalian evolutionQ36404242
The molecular mechanism of B cell activation by toll-like receptor protein RP-105Q36851787
NIH conference. Systemic lupus erythematosusQ37284985
Human immunoglobulin selection associated with class switch and possible tolerogenic origins for C delta class-switched B cellsQ37370476
Anti-B cell autoantibodies encoded by VH 4-21 genes in human fetal spleen do not require in vivo somatic selectionQ38302017
Carbohydrate-mediated Phagocytic Recognition of Early Apoptotic Cells Undergoing Transient Capping of CD43 GlycoproteinQ38348126
Human monoclonal antibodies encoded by the V4-34 gene segment show cold agglutinin activity and variable multireactivity which correlates with the predicted charge of the heavy-chain variable region.Q51647711
Maintenance of serological memory by polyclonal activation of human memory B cells.Q52008907
CD27 expression in the human splenic marginal zone: the infant marginal zone is populated by naive B cells.Q52015244
Bm1-Bm5 classification of peripheral blood B cells reveals circulating germinal center founder cells in healthy individuals and disturbance in the B cell subpopulations in patients with primary Sjögren's syndrome.Q52017280
Neonatal invariant Valpha24+ NKT lymphocytes are activated memory cells.Q52025852
Unaltered phenotype, tissue distribution and function of Valpha14(+) NKT cells in germ-free mice.Q52029252
A new role for B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/lpr mice.Q52039800
IgMhighCD21high lymphocytes enriched in the splenic marginal zone generate effector cells more rapidly than the bulk of follicular B cells.Q52176594
The human heavy chain Ig V region gene repertoire is biased at all stages of B cell ontogeny, including early pre-B cells.Q52194040
Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus.Q53718320
VH restriction among human cold agglutinins. The VH4-21 gene segment is required to encode anti-I and anti-i specificities.Q53911374
The impact of T helper and T regulatory cells on the regulation of anti-double-stranded DNA B cellsQ56904544
Erythrocyte receptors for Mycoplasma pneumoniae are sialylated oligosaccharides of Ii antigen typeQ58830620
The I and i antigens on certain normal and pathologic tissuesQ58830669
Search for I Antigen in Human TissuesQ58830691
The I Binding Specificity of Human VH4-34 (VH4-21) Encoded Antibodies is Determined by Both VHFramework Region 1 and Complementarity Determining Region 3Q62028840
The Immunoglobulin VHGene, VH4-21, Specifically Encodes Autoanti-Red Cell Antibodies against the I or i AntigensQ62028855
Autoanti-red cell antibodies synthesized by patients with infectious mononucleosis utilize the VH4-21 gene segmentQ62028862
IDENTIFICATION OF THE 9G4 IDIOTOPE IN SYSTEMIC LUPUS ERYTHEMATOSUSQ62028865
Utilization of the VH4-21 Gene Segment by Anti-DNA Antibodies from Patients with Systemic Lupus ErythematosusQ62028866
Brain-reactive lymphocytotoxic antibody in the cerebrospinal fluid of patients with systemic lupus erythematosus: correlation with central nervous system involvementQ71472328
The V4-34 encoded anti-i autoantibodies recognize a large subset of human and mouse B-cellsQ71808681
Antitumor cytotoxicity mediated by ligand-activated human V alpha24 NKT cellsQ73121259
Reciprocal regulation of polarized cytokine production by effector B and T cellsQ73256871
Control of early viral and bacterial distribution and disease by natural antibodiesQ73257312
Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetesQ74455329
Accumulation of splenic B1a cells with potent antigen-presenting capability in NZM2410 lupus-prone miceQ77341412
Quantitative and qualitative control of antigen receptor signalling in tolerant B lymphocytesQ77370086
Peripheral blood lymphocytes in SLE--hyperexpression of CD154 on T and B lymphocytes and increased number of double negative T cellsQ77514534
Rituximab improves peripheral B cell abnormalities in human systemic lupus erythematosusQ80969796
Blood-group precursors and cancer-related antigensQ39342631
Polymorphisms of immunologically relevant loci in human disease. Autoimmunity and human heavy chain variable regionsQ39610044
The blood group Ii system: a carbohydrate antigen system defined by naturally monoclonal or oligoclonal autoantibodies of man.Q40101433
Structural and biological aspects of blood group I and i antigens on glycolipids and glycoproteins.Q40299328
Self-tolerance checkpoints in B lymphocyte developmentQ40373293
Autoimmunity-prone B-1 (CD5 B) cells, natural antibodies and self recognitionQ40387286
The combination of apoptotic U937 cells and lupus IgG is a potent IFN-alpha inducerQ40856408
Cutting edge: a role for CD1 in the pathogenesis of lupus in NZB/NZW miceQ40881650
Recognition of auto- and exoantigens by V4-34 gene encoded antibodiesQ40903369
A human monoclonal antibody encoded by the V4-34 gene segment recognises melanoma-associated ganglioside via CDR3 and FWR1.Q40941960
Self glycolipids as T-cell autoantigensQ40950196
CpG DNA: a pathogenic factor in systemic lupus erythematosus?Q40954780
Rapid cytotoxicity of human B lymphocytes induced by VH4-34 (VH4.21) gene-encoded monoclonal antibodiesQ41189347
Pattern of usage of the VH4-21 gene by B lymphocytes in a patient with EBV infection indicates ongoing mutation and class switching.Q41293335
The cross-reactive idiotopes recognized by the monoclonal antibodies 9G4 and LC1 are located in framework region 1 of two non-overlapping subsets of human VH4 family encoded antibodiesQ41456692
Two acquired immunodeficiency syndrome-associated Burkitt's lymphomas produce specific anti-i IgM cold agglutinins using somatically mutated VH4-21 segmentsQ41467818
Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoireQ41505077
VH4.21-encoded natural autoantibodies with anti-i specificity mirror those associated with cold hemagglutinin disease.Q41513412
An anti-B cell autoantibody from Wiskott-Aldrich syndrome which recognizes i blood group specificity on normal human B cellsQ41615089
Variable region gene analysis of pathologic human autoantibodies to the related i and I red blood cell antigensQ41659679
VH4-34 encoded antibodies in systemic lupus erythematosus: a specific diagnostic marker that correlates with clinical disease characteristicsQ41685711
Human monoclonal antibodies against blood group antigens preferentially express a VH4-21 variable region gene-associated epitopeQ41832024
CD1b restricts the response of human CD4-8- T lymphocytes to a microbial antigenQ41939036
Human immunoglobulin (Ig)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cellsQ42108183
Human antilipid A monoclonal antibodies bind to human B cells and the i antigen on cord red blood cells.Q42278239
An intrinsic B cell defect is required for the production of autoantibodies in the lpr model of murine systemic autoimmunityQ42941505
B-1a B cells that link the innate and adaptive immune responses are lacking in the absence of the spleenQ42944730
B cells control the migration of a subset of dendritic cells into B cell follicles via CXC chemokine ligand 13 in a lymphotoxin-dependent fashionQ43982539
Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigensQ44296985
T cell receptor alpha/beta expressing double-negative (CD4-/CD8-) and CD4+ T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritisQ44381577
Presence and significance of cold agglutinins in patients with HIV infectionQ44419906
Cutting edge: germinal centers formed in the absence of B cell-activating factor belonging to the TNF family exhibit impaired maturation and functionQ44504176
Lupus IgG VH4.34 antibodies bind to a 220-kDa glycoform of CD45/B220 on the surface of human B lymphocytesQ44807477
Polymorphism of the human Ig VH4 gene familyQ44920637
Identification of normal B-cell counterparts of neoplastic cells which secrete cold agglutinins of anti-I and anti-i specificityQ45251308
Systemic lupus erythematosus in adults is associated with previous Epstein-Barr virus exposureQ45737398
CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+T cellsQ45971909
An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunityQ46113259
VH4-34 encoded antibody in systemic lupus erythematosus: effect of isotypeQ46180720
Anti-endotoxin human monoclonal antibody A6H4C5 (HA-1A) utilizes the VH4.21 geneQ46339196
Common patterns of B cell perturbation and expanded V4-34 immunoglobulin gene usage in autoimmunity and infectionQ47680938
Cold agglutinin anti-I and Mycoplasma pneumoniaeQ47705943
Immunochemical studies of mammalian glycoproteins with blood group I activityQ47917738
Variable region gene segment utilization in rhesus monkey hybridomas producing human red blood cell-specific antibodies: predominance of the VH4 family but not VH4-21 (V4-34).Q48054058
Dual recognition of lipid A and DNA by human antibodies encoded by the VH4-21 gene: a possible link between infection and lupus.Q48076799
Polymorphism of human immunoglobulin VH4 germ-line genesQ48179923
P433issue4
P304page(s)433-452
P577publication date2005-01-05
P1433published inSeminars in ImmunopathologyQ15724576
P1476titleHuman innate B cells: a link between host defense and autoimmunity?
P478volume26

Reverse relations

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