CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function

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CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function is …
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scholarly articleQ13442814

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P356DOI10.1084/JEM.192.11.1553
P932PMC publication ID2193097
P698PubMed publication ID11104798
P5875ResearchGate publication ID12222851

P2093author name stringMoser B
Lipp M
Loetscher P
Willimann K
Lang AB
Schaerli P
P2860cites workICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28Q22001503
B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5Q24309316
Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytesQ24324518
A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytesQ24681916
T-cell co-stimulation through B7RP-1 and ICOSQ28141589
A chemokine-driven positive feedback loop organizes lymphoid folliclesQ28142202
Cutting edge: identification of GL50, a novel B7-like protein that functionally binds to ICOS receptorQ28143996
International union of pharmacology. XXII. Nomenclature for chemokine receptorsQ28145705
Two subsets of memory T lymphocytes with distinct homing potentials and effector functionsQ28146072
A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1Q28263524
A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleenQ28300225
CD4 T cell cytokine differentiation: the B cell activation molecule, OX40 ligand, instructs CD4 T cells to express interleukin 4 and upregulates expression of the chemokine receptor, Blr-1Q28508535
CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organsQ28594485
Chemokines: a new classification system and their role in immunityQ29615663
Chemokines and leukocyte trafficQ29618886
Lymphocyte homing and homeostasisQ29619924
B7h, a novel costimulatory homolog of B7.1 and B7.2, is induced by TNFalphaQ30807749
Activation of blood T lymphocytes down-regulates CXCR4 expression and interferes with propagation of X4 HIV strainsQ31978803
Chemokines and B-cell homing to follicles.Q33681306
The role of chemokines in regulating cell migration during humoral immune responsesQ33778602
Chemokines and their receptors in lymphocyte traffic and HIV infectionQ33799800
Chemokines and cell migration in secondary lymphoid organsQ33807114
The reduced expression of 6Ckine in the plt mouse results from the deletion of one of two 6Ckine genesQ33877237
Chemokines in tissue-specific and microenvironment-specific lymphocyte homingQ33898971
The role of chemokine receptors in primary, effector, and memory immune responsesQ33932742
Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleenQ34488105
Interleukin-2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes.Q36367109
Developmental switches in chemokine response profiles during B cell differentiation and maturationQ36368436
In vivo-activated CD4 T cells upregulate CXC chemokine receptor 5 and reprogram their response to lymphoid chemokinesQ36375434
The role of chemokines in the microenvironmental control of T versus B cell arrest in Peyer's patch high endothelial venulesQ36375848
The CC chemokine thymus-derived chemotactic agent 4 (TCA-4, secondary lymphoid tissue chemokine, 6Ckine, exodus-2) triggers lymphocyte function-associated antigen 1-mediated arrest of rolling T lymphocytes in peripheral lymph node high endothelial vQ36375878
BCA-1 is highly expressed in Helicobacter pylori-induced mucosa-associated lymphoid tissue and gastric lymphomaQ36762885
Lymphocyte homing: the scent of a follicle.Q41480493
Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometryQ41678727
BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis.Q41740089
Compromised OX40 function in CD28-deficient mice is linked with failure to develop CXC chemokine receptor 5-positive CD4 cells and germinal centers.Q42006087
Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localizationQ42064511
Intracellular and surface expression of the HIV-1 coreceptor CXCR4/fusin on various leukocyte subsets: rapid internalization and recycling upon activationQ42830620
Secondary lymphoid-tissue chemokine (SLC) stimulates integrin alpha 4 beta 7-mediated adhesion of lymphocytes to mucosal addressin cell adhesion molecule-1 (MAdCAM-1) under flow.Q46224027
The chemokine SLC is expressed in T cell areas of lymph nodes and mucosal lymphoid tissues and attracts activated T cells via CCR7Q47915773
A novel mutant gene involved in T-lymphocyte-specific homing into peripheral lymphoid organs on mouse chromosome 4Q52039534
Chemokines and the Arrest of Lymphocytes Rolling Under Flow ConditionsQ52040689
CXCR5-deficient mice develop functional germinal centers in the splenic T cell zoneQ52974230
Constitutive expression of stromal derived factor-1 by mucosal epithelia and its role in HIV transmission and propagation.Q54056919
Expression of the G-protein--coupled receptor BLR1 defines mature, recirculating B cells and a subset of T-helper memory cellsQ72686189
Activation-dependent modulation of B lymphocyte migration to chemokinesQ74247915
Cutting edge: secondary lymphoid-tissue chemokine (SLC) and CC chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodesQ74595801
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)1553-1562
P577publication date2000-12-01
P1433published inJournal of Experimental MedicineQ3186912
P1476titleCXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function
P478volume192

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Q58234807Identification of CXCL13 as a marker for rheumatoid arthritis outcome using an in silico model of the rheumatic joint
Q37625985Identification of novel markers for mouse CD4(+) T follicular helper cells
Q47358806Identity and Diversity of Human Peripheral Th and T Regulatory Cells Defined by Single-Cell Mass Cytometry
Q55651751Immune Cell Dynamics Unfolded by Single-Cell Technologies.
Q47600062Immune Interventions to Eliminate the HIV Reservoir
Q38928447Immune Regulation of sickle Cell Alloimmunization
Q37610907Immune characteristics study of AG490, a signal pathway inhibitor, in EAE model mice
Q37993803Immune tolerance: are regulatory T cell subsets needed to explain suppression of autoimmunity?
Q38237119Immuno-miRs: critical regulators of T-cell development, function and ageing
Q39108760Immunologic characteristics of HIV-infected individuals who make broadly neutralizing antibodies.
Q35659533Immunological mechanisms of vaccination
Q37982064Immunopathological roles of cytokines, chemokines, signaling molecules, and pattern-recognition receptors in systemic lupus erythematosus
Q55039421Immunophenotypic characterization of CSF B cells in virus-associated neuroinflammatory diseases.
Q45735802Immunopotentiation of DNA vaccine against herpes simplex virus via co-delivery of plasmid DNA expressing CCR7 ligands
Q93108410Impact of Superantigen-Producing Bacteria on T Cells from Tonsillar Hyperplasia
Q36141874Impaired peripheral blood T-follicular helper cell function in HIV-infected nonresponders to the 2009 H1N1/09 vaccine
Q51012917Importance of B cell co-stimulation in CD4+ T cell differentiation: X-linked agammaglobulinaemia, a human model
Q74666178In vivo activated T cells in rheumatoid synovitis. Analysis of Th1- and Th2-type cytokine production at clonal level in different stages of disease
Q47370276In vivo expression of interleukin-8, and regulated on activation, normal, T-cell expressed, and secreted, by human germinal centre B lymphocytes
Q33936471In vivo regulation of Bcl6 and T follicular helper cell development
Q30428685Increase in IFNγ−IL-2+ Cells in Recent Human CD4 T Cell Responses to 2009 Pandemic H1N1 Influenza
Q40593574Increased CD4(+)CXCR5(+)T follicular helper cells in diabetic nephropathy
Q35829453Increased circulating follicular helper T cells with decreased programmed death-1 in chronic renal allograft rejection.
Q33809995Increased frequency of circulating follicular helper T cells in children with hand, foot, and mouth disease caused by enterovirus 71 infection.
Q36724197Increased frequency of thymic T follicular helper cells in myasthenia gravis patients with thymoma
Q35091220Inducible deletion of CD28 prior to secondary nippostrongylus brasiliensis infection impairs worm expulsion and recall of protective memory CD4⁺ T cell responses
Q36752092Induction of ICOS+CXCR3+CXCR5+ TH cells correlates with antibody responses to influenza vaccination
Q40355338Induction of IL21 in Peripheral T Follicular Helper Cells Is an Indicator of Influenza Vaccine Response in a Previously Vaccinated HIV-Infected Pediatric Cohort.
Q61803783Induction of Plasmodium-Specific Immune Responses Using Liposome-Based Vaccines
Q42683418Infection with Toxoplasma gondii Alters Lymphotoxin Expression Associated with Changes in Splenic Architecture
Q38169798Inflammatory and immune pathways in the pathogenesis of periodontal disease
Q37117567Influencing the fates of CD4 T cells on the path to memory: lessons from influenza.
Q39909362Inhibition of G Protein βγ Subunit Signaling Abrogates Nephritis in Lupus-Prone Mice
Q58777530Insights Into the Molecular Mechanisms of T Follicular Helper-Mediated Immunity and Pathology
Q38114912Insights into B cells and HIV‐specific B‐cell responses in HIV‐infected individuals
Q38875184Insights into the development and regulation of T follicular helper cells.
Q37617212Insights into the role of follicular helper T cells in autoimmunity
Q38163422Interleukin-21 and T follicular helper cells in HIV infection: research focus and future perspectives
Q36978831Interleukin-21 is a critical cytokine for the generation of virus-specific long-lived plasma cells.
Q37129666Interleukin-6/STAT3 signaling regulates the ability of naive T cells to acquire B-cell help capacities
Q33604206Intestinal microbiota link lymphopenia to murine autoimmunity via PD-1+CXCR5-/dim B-helper T cell induction
Q42266631Intrinsic T‐ and B‐cell defects impair T‐cell‐dependent antibody responses in mice lacking the actin‐bundling protein L‐plastin
Q37322505Invariant natural killer T cells direct B cell responses to cognate lipid antigen in an IL-21-dependent manner
Q37780347Key concepts in immunology
Q47845253Kinetics of CCR7 expression differ between primary activation and effector memory states of T(H)1 and T(H)2 cells
Q30421782LAPCs promote follicular helper T cell differentiation of Ag-primed CD4+ T cells during respiratory virus infection
Q91275305LCMV-specific CD4 T cell dependent polyclonal B-cell activation upon persistent viral infection is short lived and extrafollicular
Q35963147LPA Promotes T Cell Recruitment through Synthesis of CXCL13.
Q30479618Leukocyte migration and graft-versus-host disease
Q26825249Life of T follicular helper cells
Q40958976Limited Internodal Migration of T Follicular Helper Cells after Peripheral Infection with Herpes Simplex Virus-1.
Q93092484Live-Attenuated Influenza Vaccine Induces Tonsillar Follicular T Helper Cell Responses That Correlate With Antibody Induction
Q45729856Liver-infiltrating lymphocytes in end-stage hepatitis C virus: subsets, activation status, and chemokine receptor phenotypes
Q37241480Loss of T Follicular Helper Cells in the Peripheral Blood of Patients with Chronic Graft-versus-Host Disease
Q58705561Low Peripheral T Follicular Helper Cells in Perinatally HIV-Infected Children Correlate With Advancing HIV Disease
Q35126450Low SAMHD1 expression following T-cell activation and proliferation renders CD4+ T cells susceptible to HIV-1.
Q98889320Low-dose influenza vaccine Grippol Quadrivalent with adjuvant Polyoxidonium induces a T helper-2 mediated humoral immune response and increases NK cell activity
Q39403538Lycium barbarum polysaccharides as an adjuvant for recombinant vaccine through enhancement of humoral immunity by activating Tfh cells
Q34139610Lymphocyte traffic control by chemokines
Q35044757Lymphocyte traffic control by chemokines: follicular B helper T cells
Q35762431Lymphocyte trafficking across high endothelial venules: dogmas and enigmas
Q46609740Lymphoid reservoirs of antigen-specific memory T helper cells
Q34688212Mast cell-derived IL-10 suppresses germinal center formation by affecting T follicular helper cell function
Q34462470Memory B cells
Q34754506Memory CD4 T cells that express CXCR5 provide accelerated help to B cells
Q26829047Memory T follicular helper CD4 T cells
Q52923050Mesenchymal Stem Cell Modulates T Follicular Helper Cell to Induce Immunotolerance of Islet Allograft
Q92569677Metabolic regulation of TH17 cells
Q53614128MiR-346 regulates CD4⁺CXCR5⁺ T cells in the pathogenesis of Graves' disease
Q37693699MicroRNA-mediated regulation of T helper cell differentiation and plasticity.
Q54325033Microarray analysis of gastric mucosa among children with Helicobacter pylori infection
Q64266635Molecular Basis of the Differentiation and Function of Virus Specific Follicular Helper CD4 T Cells
Q58556221Molecular Control of Follicular Helper T cell Development and Differentiation
Q37474929Molecular mechanism and function of CD40/CD40L engagement in the immune system.
Q36376366Monocyte selectivity and tissue localization suggests a role for breast and kidney-expressed chemokine (BRAK) in macrophage development
Q24300326Monocyte-like and mature macrophages produce CXCL13 (B cell-attracting chemokine 1) in inflammatory lesions with lymphoid neogenesis
Q36209689Mucosal B cells: phenotypic characteristics, transcriptional regulation, and homing properties
Q92199134Mucosal T follicular helper cells in SIV-infected rhesus macaques: contributing role of IL-27
Q43255281Multiple layers of B cell memory with different effector functions
Q42129350Mutual interaction between BCL6 and microRNAs in T cell differentiation
Q28384506Mycobacterium tuberculosis-Specific IL-21+IFN-γ+CD4+ T Cells Are Regulated by IL-12
Q41924234Myeloid-Derived Suppressor Cells Inhibit T Follicular Helper Cell Immune Response in Japanese Encephalitis Virus Infection.
Q35080934Myor/ABF-1 mRNA [corrected] Expression Marks Follicular Helper T Cells but Is Dispensable for Tfh Cell Differentiation and Function In Vivo
Q34516552Naive and memory B cells in T-cell-dependent and T-independent responses
Q34257343Nematode-induced interference with vaccination efficacy targets follicular T helper cell induction and is preserved after termination of infection
Q35081201Neuropilin-1 expression characterizes T follicular helper (Tfh) cells activated during B cell differentiation in human secondary lymphoid organs.
Q38032202New helping friends for B cells
Q37621244New insights into the differentiation and function of T follicular helper cells.
Q52017157Nonpolarized memory T cells
Q57049820Notch2-dependent DC2s mediate splenic germinal center responses
Q38057797Novel pharmacological approaches for treatment of obstructive sleep apnea in children
Q99710907Ontogeny of different subsets of yellow fever virus-specific circulatory CXCR5+ CD4+ T cells after yellow fever vaccination
Q24322068Overexpression of the CXCR5 chemokine receptor, and its ligand, CXCL13 in B-cell chronic lymphocytic leukemia
Q35633382Overexpression of the Ctla-4 isoform lacking exons 2 and 3 causes autoimmunity
Q40072523P2X7 receptor drives Th1 cell differentiation and controls the follicular helper T cell population to protect against Plasmodium chabaudi malaria.
Q35146249PD-1 expression defines two distinct T-cell sub-populations in follicular lymphoma that differentially impact patient survival
Q40653907PD-1(+) and follicular helper T cells are responsible for persistent HIV-1 transcription in treated aviremic individuals
Q33748674PPARγ negatively regulates T cell activation to prevent follicular helper T cells and germinal center formation
Q37600124PTPN22 controls the germinal center by influencing the numbers and activity of T follicular helper cells
Q40546838PU.1 Expression in T Follicular Helper Cells Limits CD40L-Dependent Germinal Center B Cell Development
Q50961894Paediatric Reference Values for the Peripheral T cell Compartment
Q38208309Paradigm Shift in Dendritic Cell-Based Immunotherapy: From in vitro Generated Monocyte-Derived DCs to Naturally Circulating DC Subsets.
Q35695090Pathophysiology of T follicular helper cells in humans and mice
Q59361053Peering into the HIV reservoir
Q47150484Peripheral T follicular helper Cells Make a Difference in HIV Reservoir Size between Elite Controllers and Patients on Successful cART.
Q36818796Peripheral T-cell lymphomas with a follicular growth pattern are derived from follicular helper T cells (TFH) and may show overlapping features with angioimmunoblastic T-cell lymphomas
Q64359404Peripheral follicular helper T cells in acute viral diseases: a perspective on dengue
Q36957851Persistence of integrated HIV DNA in CXCR3 + CCR6 + memory CD4+ T cells in HIV-infected individuals on antiretroviral therapy
Q38226748Phenotype and functions of memory Tfh cells in human blood
Q34018408Phenotype, effector function, and tissue localization of PD-1-expressing human follicular helper T cell subsets
Q38172562Phenotypic and functional plasticity of gamma-delta (γδ) T cells in inflammation and tolerance
Q92106794Plasma IL-5 but Not CXCL13 Correlates With Neutralization Breadth in HIV-Infected Children
Q38265506Potential Use of γδ T Cell-Based Vaccines in Cancer Immunotherapy.
Q91707896Predominantly Antibody-Deficient Patients With Non-infectious Complications Have Reduced Naive B, Treg, Th17, and Tfh17 Cells
Q51769095Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer's patches
Q36128625Production of Autoantibodies in Chronic Hepatitis B Virus Infection Is Associated with the Augmented Function of Blood CXCR5+CD4+ T Cells
Q35014086Progressive differentiation and selection of the fittest in the immune response
Q34504850Proinflammatory adjuvants enhance the cognate helper activity of aged CD4 T cells
Q54242204Prolonged follicular helper T cell responses in ME7 scrapie-infected mice
Q34262180Prophylaxis with a respiratory syncytial virus (RSV) anti-G protein monoclonal antibody shifts the adaptive immune response to RSV rA2-line19F infection from Th2 to Th1 in BALB/c mice
Q39142683Protein structure shapes immunodominance in the CD4 T cell response to yellow fever vaccination
Q86646045Quantitative analysis of target coverage and germinal center response by a CXCL13 neutralizing antibody in a T-dependent mouse immunization model
Q39582808ROCK2 signaling is required to induce a subset of T follicular helper cells through opposing effects on STATs in autoimmune settings
Q38574697Rapid culling of the CD4+ T cell repertoire in the transition from effector to memory
Q37084889Real-time imaging of the cellular interactions underlying tolerance, priming, and responses to infection
Q38439088Rebamipide attenuates autoimmune arthritis severity in SKG mice via regulation of B cell and antibody production
Q52725593Recognition of microbial viability via TLR8 drives TFH cell differentiation and vaccine responses
Q92906781Recurrent Tonsillitis Tfh Cells Acquire a Killer Identity
Q48290216Refinement of humoral immune monitoring in kidney transplantation: the role of "hidden" alloreactive memory B cells
Q57175036Regulation of T Follicular Helper Cells in Islet Autoimmunity
Q36543544Regulation of T(H)2 development by CXCR5+ dendritic cells and lymphotoxin-expressing B cells
Q26829573Regulatory T cells and control of the germinal centre response
Q41834768Regulatory T cells and the control of the allergic response.
Q36075224Regulatory and Helper Follicular T Cells and Antibody Avidity to Simian Immunodeficiency Virus Glycoprotein 120.
Q55396042Relapsing-Remitting Multiple Sclerosis Is Characterized by a T Follicular Cell Pro-Inflammatory Shift, Reverted by Dimethyl Fumarate Treatment.
Q28728810Retracted: IL-21 Regulates the Differentiation of a Human γδ T Cell Subset Equipped with B Cell Helper Activity
Q34635510Rhesus macaque lymph node PD-1(hi)CD4+ T cells express high levels of CXCR5 and IL-21 and display a CCR7(lo)ICOS+Bcl6+ T-follicular helper (Tfh) cell phenotype
Q46317472Rheumatoid arthritis fibroblast-like synoviocytes co-cultured with PBMC increased peripheral CD4+ CXCR5+ ICOS+ T cell numbers.
Q37872661Rituximab for prevention and treatment of graft-versus-host disease
Q36670538Role of IL-21 and IL-21 Receptor on B Cells in HIV Infection
Q36603870Role of T follicular helper cells and their associated molecules in the pathogenesis of chronic hepatitis B virus infection
Q58580426Role of TRAFs in Signaling Pathways Controlling T Follicular Helper Cell Differentiation and T Cell-Dependent Antibody Responses
Q37765477Role of lymphotoxin and homeostatic chemokines in the development and function of local lymphoid tissues in the respiratory tract.
Q24310725Roquin differentiates the specialized functions of duplicated T cell costimulatory receptor genes CD28 and ICOS
Q39947109Rules of chemokine receptor association with T cell polarization in vivo
Q37001206SAP enables T cells to help B cells by a mechanism distinct from Th cell programming or CD40 ligand regulation
Q98665479SARS-CoV-2-specific T cells exhibit phenotypic features of robust helper function, lack of terminal differentiation, and high proliferative potential
Q50348783STAT3 regulates cytotoxicity of human CD57+ CD4+ T cells in blood and lymphoid follicles
Q34907773STAT3 signaling induces the differentiation of human ICOS(+) CD4 T cells helping B lymphocytes
Q47355847STAT4 and T-bet control follicular helper T cell development in viral infections.
Q90608769SUMO-defective c-Maf preferentially transactivates Il21 to exacerbate autoimmune diabetes
Q93157505Safety and tolerance of lymph node biopsies from chronic HIV-1 volunteers in rural Tanzania
Q33182376Separable effector T cell populations specialized for B cell help or tissue inflammation
Q56603390Shaping Up Adaptive Immunity: The Impact of CCR7 and CXCR5 on Lymphocyte Trafficking
Q28203125Signal Transduction by the Chemokine Receptor CXCR5: Structural Requirements for G Protein Activation Analyzed by Chimeric CXCR1/CXCR5 Molecules
Q37682640Signals that influence T follicular helper cell differentiation and function.
Q52608538Simian Immunodeficiency Virus (SIV)-Specific Chimeric Antigen Receptor-T Cells Engineered to Target B Cell Follicles and Suppress SIV Replication
Q36155603Single and Coexpression of CXCR4 and CXCR5 Identifies CD4 T Helper Cells in Distinct Lymph Node Niches during Influenza Virus Infection
Q37720375Single-cell RNA-seq and computational analysis using temporal mixture modelling resolves Th1/Tfh fate bifurcation in malaria
Q35850901Spatial Alterations between CD4+ T Follicular Helper, B, and CD8+ T Cells during Simian Immunodeficiency Virus Infection: T/B Cell Homeostasis, Activation, and Potential Mechanism for Viral Escape
Q36821138Spatial distribution of B cells predicts prognosis in human pancreatic adenocarcinoma.
Q102075519Spike-specific circulating T follicular helper cell and cross-neutralizing antibody responses in COVID-19-convalescent individuals
Q40343247Spontaneous germinal centers and autoimmunity
Q36009259Stat3 Is Important for Follicular Regulatory T Cell Differentiation
Q45416054Studies on GM-CSF DNA as an adjuvant for neutralizing Ab elicited by a DNA/MVA immunodeficiency virus vaccine
Q36368917Subspecialization of CXCR5+ T cells: B helper activity is focused in a germinal center-localized subset of CXCR5+ T cells
Q43164202Survivin co-ordinates formation of follicular T-cells acting in synergy with Bcl-6.
Q47570502Sustained T follicular helper cell response is essential for control of chronic viral infection.
Q60810884Systematic microanatomical analysis of CXCL13 and CCL21in situ production and progressive lymphoid organization in rheumatoid synovitis
Q52657148T Cell Subsets in the Germinal Center: Lessons from the Macaque Model
Q58712847T Cells That Help B Cells in Chronically Inflamed Tissues
Q92538835T Follicular Helper Cell Subsets and the Associated Cytokine IL-21 in the Pathogenesis and Therapy of Asthma
Q90675716T Follicular Helper Cells in Autoimmune Disorders
Q94502761T Follicular Regulatory Cell Suppression of T Follicular Helper Cell Function Is Context-Dependent in vitro
Q99711563T Helper (Th) Cell Profiles in Pregnancy and Recurrent Pregnancy Losses: Th1/Th2/Th9/Th17/Th22/Tfh Cells
Q26829272T Helper Subsets, Peripheral Plasticity, and the Acute Phase Protein, α1-Antitrypsin
Q47924291T and IgA B lymphocytes of the pharyngeal and palatine tonsils: differential expression of adhesion molecules and chemokines
Q41895228T cell accumulation in B cell follicles is regulated by dendritic cells and is independent of B cell activation
Q34296494T cell effector subsets: extending the Th1/Th2 paradigm
Q37773235T cell help to B cells in germinal centers: putting the jigsaw together
Q64890943T cell pathology in skin inflammation.
Q43742714T cell receptor (TCR) signal strength controls arthritis severity in proteoglycan-specific TCR transgenic mice
Q37979859T cell-B cell interactions in primary immunodeficiencies
Q38002491T cells that promote B‐Cell maturation in systemic autoimmunity
Q38771318T follicular helper (Tfh ) cells in normal immune responses and in allergic disorders
Q38827181T follicular helper and T follicular regulatory cells have different TCR specificity.
Q36823844T follicular helper cell diversity and plasticity
Q92382973T follicular helper cell heterogeneity: Time, space, and function
Q38904415T follicular helper cell programming by cytokine-mediated events.
Q91755050T follicular helper cells and T follicular regulatory cells in rheumatic diseases
Q37783748T follicular helper cells during immunity and tolerance.
Q38940412T follicular helper cells in space-time.
Q38685919T follicular helper cells in the generation of alloantibody and graft rejection
Q38682344T follicular helper cells, T follicular regulatory cells and autoimmunity.
Q38920904T follicular helper cells, interleukin-21 and systemic lupus erythematosus.
Q34327596T-cell subsets in the germinal center.
Q92282217TCR Affinity Biases Th Cell Differentiation by Regulating CD25, Eef1e1, and Gbp2
Q42910834TIGIT-positive circulating follicular helper T cells and sickle cell alloimmunization
Q36779751TIGIT-positive circulating follicular helper T cells display robust B-cell help functions: potential role in sickle cell alloimmunization
Q40448733TIR-Domain-Containing Adapter-Inducing Interferon-β (TRIF) Regulates CXCR5+ T helper Cells in the Intestine.
Q35105613Tailored immune responses: novel effector helper T cell subsets in protective immunity
Q38098493Targeting cells in motion: Migrating toward improved therapies
Q37833270Targeting human dendritic cell subsets for improved vaccines
Q26742168Tertiary Lymphoid Organs in Cancer Tissues
Q27335276Th17 effector cells support B cell responses outside of germinal centres
Q28067520The Dynamics of T and B Cells in Lymph Node during Chronic HIV Infection: TFH and HIV, Unhappy Dance Partners?
Q92254395The E3 ligase VHL promotes follicular helper T cell differentiation via glycolytic-epigenetic control
Q54987756The Janus Face of Follicular T Helper Cells in Chronic Viral Infections.
Q54976848The Kinase Complex mTOR Complex 2 Promotes the Follicular Migration and Functional Maturation of Differentiated Follicular Helper CD4+ T Cells During Viral Infection.
Q92878024The Prognostic Landscape of Tumor-Infiltrating Immune Cells and Immune Checkpoints in Glioblastoma
Q39134294The Role of CD4+ T Follicular Helper Cells in HIV Infection: From the Germinal Center to the Periphery
Q26745851The Role of Lymphatic Niches in T Cell Differentiation
Q28070412The Role of Lymphocytes in Radiotherapy-Induced Adverse Late Effects in the Lung
Q64102236The Transcription Factor T-Bet Is Required for Optimal Type I Follicular Helper T Cell Maintenance During Acute Viral Infection
Q24599502The aged microenvironment contributes to the age‐related functional defects of CD4 T cells in mice
Q24655751The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells
Q33877993The curious origins of angioimmunoblastic T-cell lymphoma
Q37724577The development and function of follicular helper T cells in immune responses
Q34252448The dysfunction of T follicular helper cells
Q34106521The effect of aging on the frequency, phenotype and cytokine production of human blood CD4 + CXCR5 + T follicular helper cells: comparison of aged and young subjects
Q37063091The effector to memory transition of CD4 T cells.
Q37784588The elusive identity of T follicular helper cells
Q34165325The expanding B7 superfamily: increasing complexity in costimulatory signals regulating T cell function
Q42236079The expression of IL6 and 21 in crossbred calves upregulated by inactivated trivalent FMD vaccine.
Q38107389The good, the bad and the ugly - TFH cells in human health and disease
Q92179712The histone methyltransferase EZH2 primes the early differentiation of follicular helper T cells during acute viral infection
Q35216957The impact of CCR7 and CXCR5 on lymphoid organ development and systemic immunity
Q38388255The importance of co-stimulation in the orchestration of T helper cell differentiation
Q35686001The influence of follicular migration on T-cell differentiation
Q36118326The origins, function, and regulation of T follicular helper cells
Q36317934The phenotype of circulating follicular-helper T cells in patients with rheumatoid arthritis defines CD200 as a potential therapeutic target
Q37210857The receptor PD-1 controls follicular regulatory T cells in the lymph nodes and blood.
Q37951500The regulation and role of T follicular helper cells in immunity
Q36584814The role of B7 family molecules in hematologic malignancy
Q24805385The role of IFN-gamma in systemic lupus erythematosus: a challenge to the Th1/Th2 paradigm in autoimmunity
Q37811046The role of SAP and SLAM family molecules in the humoral immune response
Q34493082The role of chemokines in linking innate and adaptive immunity
Q51102870The role of follicular T helper cells in patients with malignant lymphoid disease
Q92687674The role of follicular T helper cells in the humoral alloimmune response after clinical organ transplantation
Q57170667The role of follicular helper CD4 T cells in the development of HIV-1 specific broadly neutralizing antibody responses
Q26824290The role of the T follicular helper cells in allergic disease
Q54249832The roles of resident, central and effector memory CD4 T-cells in protective immunity following infection or vaccination
Q48333510The temporospatial control of Tfh cells
Q28590835The transcription factor Foxp1 is a critical negative regulator of the differentiation of follicular helper T cells
Q41088363The transcription factor TCF-1 initiates the differentiation of T(FH) cells during acute viral infection.
Q37149425The transcriptional coactivator Bob1 promotes the development of follicular T helper cells via Bcl6
Q35111225The transforming growth factor beta signaling pathway is critical for the formation of CD4 T follicular helper cells and isotype-switched antibody responses in the lung mucosa
Q38121496The unique features of follicular T cell subsets
Q38164599The who's who of T-cell differentiation: human memory T-cell subsets
Q53632191Toll-like receptor stimulation as a third signal required for activation of human naive B cells
Q36001333Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation
Q39163678Transcriptional and epigenetic regulation of follicular T-helper cells and their role in autoimmunity
Q38081173Transcriptional regulation of follicular T‐helper (Tfh) cells
Q104068523Treg cell therapy: how cell heterogeneity can make the difference
Q37666675Type I IFN induces binding of STAT1 to Bcl6: divergent roles of STAT family transcription factors in the T follicular helper cell genetic program
Q38835389Ubiquitin Ligases and Deubiquitinating Enzymes in CD4+ T Cell Effector Fate Choice and Function
Q34091987Unbalanced Neonatal CD4(+) T-Cell Immunity
Q37728834Understanding the development and function of T follicular helper cells.
Q90259295Unexpected Help: Follicular Regulatory T Cells in the Germinal Center
Q95846610Unexpected enhancement of FVIII immunogenicity by endothelial expression in lentivirus-transduced and transgenic mice
Q51512089Unexplained infertility patients have increased serum IL-2, IL-4, IL-6, IL-8, IL-21, TNFα, IFNγ and increased Tfh/CD4 T cell ratio: increased Tfh and IL-21 strongly correlate with presence of autoantibodies
Q50558366Unlike αβ T cells, γδ T cells, LTi cells and NKT cells do not require IRF4 for the production of IL-17A and IL-22.
Q47131777Up-regulation of Interleukin-21 Contributes to Liver Pathology of Schistosomiasis by Driving GC Immune Responses and Activating HSCs in Mice
Q35848582Upon viral exposure, myeloid and plasmacytoid dendritic cells produce 3 waves of distinct chemokines to recruit immune effectors
Q60930481Variation in IL-21-secreting circulating follicular helper T cells in Kawasaki disease
Q30409296Viral infection of the lung: Host response and sequelae
Q98291353Virus-Specific T Cell Therapies for HIV: Lessons Learned From Hematopoietic Stem Cell Transplantation
Q33872168Yin-Yang of costimulation: crucial controls of immune tolerance and function
Q36732665gammadelta T cells: novel initiators of adaptive immunity.
Q34378756gp130 at the nexus of inflammation, autoimmunity, and cancer
Q47736893mRNA vaccines - a new era in vaccinology
Q37875768γδ T-APCs: a novel tool for immunotherapy?
Q26994963γδ-T cells: an unpolished sword in human anti-infection immunity

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