CXCR5+PD1+ICOS+ Circulating T Follicular Helpers Are Associated With de novo Donor-Specific Antibodies After Renal Transplantation

scientific article published on 10 September 2019

CXCR5+PD1+ICOS+ Circulating T Follicular Helpers Are Associated With de novo Donor-Specific Antibodies After Renal Transplantation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FIMMU.2019.02071
P932PMC publication ID6746839
P698PubMed publication ID31552030

P50authorSophie ConchonQ57130952
P2093author name stringNicolas Degauque
Sophie Brouard
Magali Giral
Anne Cesbron
Mélanie Chesneau
Richard Danger
Simon Ville
Alexis Chenouard
Florent Delbos
Clarisse Kerleau
Sabine Le Bot
P2860cites workFollicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin productionQ24676570
ICOS(+)PD-1(+)CXCR3(+) T follicular helper cells contribute to the generation of high-avidity antibodies following influenza vaccinationQ30388557
Immune reconstitution following rabbit antithymocyte globulin.Q33827314
T follicular helper expansion and humoral-mediated rejection are independent of the HVEM/BTLA pathwayQ33920121
Cell distance mapping identifies functional T follicular helper cells in inflamed human renal tissueQ34030907
Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretionQ34615273
Diagnosis and management of antibody-mediated rejection: current status and novel approachesQ34841849
Increased circulating follicular helper T cells with decreased programmed death-1 in chronic renal allograft rejection.Q35829453
Germinal center alloantibody responses are mediated exclusively by indirect-pathway CD4 T follicular helper cellsQ36043667
Memory CD4+ T-cell-mediated protection depends on secondary effectors that are distinct from and superior to primary effectorsQ36280048
CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper functionQ36368291
IgG Donor-Specific Anti-Human HLA Antibody Subclasses and Kidney Allograft Antibody-Mediated InjuryQ36417907
T follicular helper (TFH) cells in normal and dysregulated immune responsesQ37049341
Costimulation blockade alters germinal center responses and prevents antibody-mediated rejectionQ37700827
Human circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responsesQ37718722
The impact of donor-specific anti-HLA antibodies on late kidney allograft failureQ38003049
Phenotype and functions of memory Tfh cells in human bloodQ38226748
T follicular helper cell differentiation, function, and roles in diseaseQ38264816
T Follicular Helper Cells in Transplantation.Q38881674
Follicular T helper cells and humoral reactivity in kidney transplant patientsQ38923388
Renal Operational Tolerance Is Associated With a Defect of Blood Tfh Cells That Exhibit Impaired B Cell Help.Q39152736
Incidence and impact of de novo donor-specific alloantibody in primary renal allograftsQ39472834
Anti-CD28 Antibody and Belatacept Exert Differential Effects on Mechanisms of Renal Allograft Rejection.Q39782306
Value of Donor-Specific Anti-HLA Antibody Monitoring and Characterization for Risk Stratification of Kidney Allograft LossQ40634986
The impact of confounder selection criteria on effect estimationQ43670469
Antibody-mediated microcirculation injury is the major cause of late kidney transplant failureQ43918875
Kinetics of homeostatic proliferation and thymopoiesis after rATG induction therapy in kidney transplant patientsQ45332668
Impact of immunosuppressive drugs on circulating Tfh cells in kidney transplant recipients: A pilot studyQ47704215
Evolution and clinical pathologic correlations of de novo donor-specific HLA antibody post kidney transplant.Q48005087
Selective CD28 Blockade Results in Superior Inhibition of Donor-Specific T Follicular Helper Cell and Antibody Responses Relative to CTLA4-IgQ48747887
Control of Humoral Response in Renal Transplantation by Belatacept Depends on a Direct Effect on B Cells and Impaired T Follicular Helper-B Cell Crosstalk.Q50102293
CD4+ T Cell Help Is Mandatory for Naive and Memory Donor-Specific Antibody Responses: Impact of Therapeutic Immunosuppression.Q50531944
Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility.Q50903417
Tertiary lymphoid tissues generate effector and memory T cells that lead to allograft rejection.Q51976995
ICOS deficiency is associated with a severe reduction of CXCR5+CD4 germinal center Th cells.Q51979261
Antibody-mediated rejection: New approaches in prevention and management.Q52401610
Allogeneic dendritic cells stimulated with antibodies against HLA class II polarize naive T cells in a follicular helper phenotype.Q52728730
Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.Q54618275
The Calcineurin Inhibitor Tacrolimus Specifically Suppresses Human T Follicular Helper Cells.Q55373807
Longitudinal profile of circulating T follicular helper lymphocytes parallels anti-HLA sensitization in renal transplant recipientsQ89274128
Circulating T follicular helper cells are a biomarker of humoral alloreactivity and predict donor-specific antibody formation after transplantationQ93098887
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P304page(s)2071
P577publication date2019-09-10
P1433published inFrontiers in ImmunologyQ27723748
P1476titleCXCR5+PD1+ICOS+ Circulating T Follicular Helpers Are Associated With de novo Donor-Specific Antibodies After Renal Transplantation
P478volume10

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