Circulating Th1-Cell-type Tfh Cells that Exhibit Impaired B Cell Help Are Preferentially Activated during Acute Malaria in Children

scientific article

Circulating Th1-Cell-type Tfh Cells that Exhibit Impaired B Cell Help Are Preferentially Activated during Acute Malaria in Children is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.CELREP.2015.09.004
P932PMC publication ID4607674
P698PubMed publication ID26440897
P5875ResearchGate publication ID282363159

P50authorOgobara K. DoumboQ3349810
Jeff SkinnerQ42645077
Tuan M TranQ50285663
Aissata OngoibaQ52291193
Sílvia PortugalQ55176191
Boubacar TraoreQ62672878
Kassoum KayentaoQ72251479
Takele YazewQ89793901
Philip L. FelgnerQ90974131
Peter D CromptonQ91078865
Aarti JainQ100753242
Nyamekye Obeng-AdjeiQ114405993
P2093author name stringShanping Li
P2860cites workImmune mechanisms in malaria: new insights in vaccine developmentQ21032484
Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150)Q24599046
Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin productionQ24676570
CD4 T-cell subsets in malaria: TH1/TH2 revisitedQ26849470
Young lives lost as B cells falter: what we are learning about antibody responses in malariaQ27687235
Two subsets of memory T lymphocytes with distinct homing potentials and effector functionsQ28146072
Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiationQ28252247
Bcl6 mediates the development of T follicular helper cellsQ28252825
Efficacy and safety of the RTS,S/AS01 malaria vaccine during 18 months after vaccination: a phase 3 randomized, controlled trial in children and young infants at 11 African sitesQ28541281
T follicular helper cell dynamics in germinal centersQ30573316
IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanismQ33656121
IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responsesQ33656146
Profiling the humoral immune response to infection by using proteome microarrays: high-throughput vaccine and diagnostic antigen discoveryQ33756925
Malaria immunity in man and mosquito: insights into unsolved mysteries of a deadly infectious diseaseQ33821137
A prospective analysis of the Ab response to Plasmodium falciparum before and after a malaria season by protein microarrayQ33859633
The RTS,S vaccine candidate for malariaQ34186762
Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infectionQ34239730
The role of ICOS in the CXCR5+ follicular B helper T cell maintenance in vivoQ34440540
Human blood CXCR5(+)CD4(+) T cells are counterparts of T follicular cells and contain specific subsets that differentially support antibody secretionQ34615273
The relationship between RTS,S vaccine-induced antibodies, CD4⁺ T cell responses and protection against Plasmodium falciparum infectionQ34684347
A fundamental role for interleukin-21 in the generation of T follicular helper cellsQ34792475
Disruption of IL-21 signaling affects T cell-B cell interactions and abrogates protective humoral immunity to malariaQ35207997
PD-1 Co-inhibitory and OX40 Co-stimulatory Crosstalk Regulates Helper T Cell Differentiation and Anti-Plasmodium Humoral ImmunityQ35611447
Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiationQ35884238
The origins, function, and regulation of T follicular helper cellsQ36118326
CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper functionQ36368291
Induction of ICOS+CXCR3+CXCR5+ TH cells correlates with antibody responses to influenza vaccinationQ36752092
An intensive longitudinal cohort study of Malian children and adults reveals no evidence of acquired immunity to Plasmodium falciparum infectionQ36892880
Distinct memory CD4+ T cells with commitment to T follicular helper- and T helper 1-cell lineages are generated after acute viral infection.Q37090620
Immunity to malaria: more questions than answersQ37194482
Inadequate T follicular cell help impairs B cell immunity during HIV infection.Q37349638
Human circulating PD-1+CXCR3-CXCR5+ memory Tfh cells are highly functional and correlate with broadly neutralizing HIV antibody responsesQ37718722
Human T follicular helper (Tfh) cells and diseaseQ38154471
Escaping the immune system: How the malaria parasite makes vaccine development a challengeQ38157335
T follicular helper cell differentiation, function, and roles in diseaseQ38264816
Duration of protection with RTS,S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of a randomised controlled trialQ38410749
Blood Tfh cells come with colorsQ38916112
Circulating precursor CCR7(lo)PD-1(hi) CXCR5⁺ CD4⁺ T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.Q42261388
Duration of humoral immunity to common viral and vaccine antigensQ45872621
Diversity among memory B cells: origin, consequences, and utility.Q46918689
A 2020 vision for vaccines against HIV, tuberculosis and malariaQ47980915
Salmonella induces a switched antibody response without germinal centers that impedes the extracellular spread of infectionQ50072223
The transcriptional repressor Bcl-6 directs T follicular helper cell lineage commitment.Q50736370
Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility.Q50903417
CXCR5 expressing human central memory CD4 T cells and their relevance for humoral immune responses.Q51013752
Bcl6 protein expression shapes pre-germinal center B cell dynamics and follicular helper T cell heterogeneity.Q55054413
Follicular B helper T cell activity is confined to CXCR5(hi)ICOS(hi) CD4 T cells and is independent of CD57 expressionQ79769520
P433issue2
P921main subjectT follicular helper cellQ5464650
malariaQ12156
P304page(s)425-439
P577publication date2015-09-30
P1433published inCell ReportsQ5058165
P1476titleCirculating Th1-Cell-type Tfh Cells that Exhibit Impaired B Cell Help Are Preferentially Activated during Acute Malaria in Children
P478volume13

Reverse relations

cites work (P2860)
Q58616106-specific atypical memory B cells are short-lived activated B cells
Q40099738A Cytokine-Independent Approach To Identify Antigen-Specific Human Germinal Center T Follicular Helper Cells and Rare Antigen-Specific CD4+ T Cells in Blood.
Q91707707A Virus Hosted in Malaria-Infected Blood Protects against T Cell-Mediated Inflammatory Diseases by Impairing DC Function in a Type I IFN-Dependent Manner
Q49270687Activated T follicular helper-like cells are released into blood after oral vaccination and correlate with vaccine specific mucosal B-cell memory
Q57185107Activation of Peripheral T Follicular Helper Cells During Acute Dengue Virus Infection
Q47106697Advances in malaria vaccine development: report from the 2017 malaria vaccine symposium
Q61805875Antibody responses to merozoite antigens after natural Plasmodium falciparum infection: kinetics and longevity in absence of re-exposure
Q91900073Antibody-Dependent, Gamma Interferon-Independent Sterilizing Immunity Induced by a Subunit Malaria Vaccine
Q39452857Atypical memory B cells in human chronic infectious diseases: An interim report
Q37635335Avidity of anti-malarial antibodies inversely related to transmission intensity at three sites in Uganda
Q92786996B cell profiling in malaria reveals expansion and remodelling of CD11c+ B cell subsets
Q59349637Basics of memory B-cell responses: lessons from and for the real world
Q37651727CD4 T Follicular Helper Cells and HIV Infection: Friends or Enemies?
Q92497684CD4+ T Follicular Helper Cells in Human Tonsils and Blood Are Clonally Convergent but Divergent from Non-Tfh CD4+ Cells
Q56357275CXCR3 T Follicular Helper Cells Induced by Co-Administration of RTS,S/AS01B and Viral-Vectored Vaccines Are Associated With Reduced Immunogenicity and Efficacy Against Malaria
Q26753848Can follicular helper T cells be targeted to improve vaccine efficacy?
Q39057013Chronic Plasmodium chabaudi Infection Generates CD4 Memory T Cells with Increased T Cell Receptor Sensitivity but Poor Secondary Expansion and Increased Apoptosis
Q64084567Development of B Cell Memory in Malaria
Q40241860Do Memory CD4 T Cells Keep Their Cell-Type Programming: Plasticity versus Fate Commitment? Complexities of Interpretation due to the Heterogeneity of Memory CD4 T Cells, Including T Follicular Helper Cells
Q46222698Evaluating anti-disease immunity to malaria and implications for vaccine design.
Q40049263Follicular Helper T Cells are Essential for the Elimination of Plasmodium Infection
Q36057301Follicular Helper T Cells in Autoimmunity.
Q37667437Follicular T Cells from smB- Common Variable Immunodeficiency Patients Are Skewed Toward a Th1 Phenotype
Q90266052Human T Cell Response to Dengue Virus Infection
Q30388557ICOS(+)PD-1(+)CXCR3(+) T follicular helper cells contribute to the generation of high-avidity antibodies following influenza vaccination
Q35863341IFN-γ and IL-21 Double Producing T Cells Are Bcl6-Independent and Survive into the Memory Phase in Plasmodium chabaudi Infection
Q36182425IFNAR1-Signalling Obstructs ICOS-mediated Humoral Immunity during Non-lethal Blood-Stage Plasmodium Infection
Q90390275IL-12 signaling drives the differentiation and function of a TH1-derived TFH1-like cell population
Q40117722IL-6 promotes CD4+ T-cell and B-cell activation during Plasmodium infection.
Q38690037Immunological processes underlying the slow acquisition of humoral immunity to malaria
Q30245481Impact of In Utero Exposure to Malaria on Fetal T Cell Immunity
Q58549248In utero priming of highly functional effector T cell responses to human malaria
Q95329458Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria
Q38605092Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4(+) Th Cells.
Q38968887Malaria - how this parasitic infection aids and abets EBV-associated Burkitt lymphomagenesis
Q58569727Malaria prevention: from immunological concepts to effective vaccines and protective antibodies
Q41993705Malaria-induced interferon-γ drives the expansion of Tbethi atypical memory B cells
Q47396685Mechanisms of naturally acquired immunity to P. falciparum and approaches to identify merozoite antigen targets
Q92199134Mucosal T follicular helper cells in SIV-infected rhesus macaques: contributing role of IL-27
Q56363429Neutralization of the Plasmodium-encoded MIF ortholog confers protective immunity against malaria infection
Q64359404Peripheral follicular helper T cells in acute viral diseases: a perspective on dengue
Q91731415Persistent expansion and Th1-like skewing of HIV-specific circulating T follicular helper cells during antiretroviral therapy
Q36143186Reduced Plasmodium Parasite Burden Associates with CD38+ CD4+ T Cells Displaying Cytolytic Potential and Impaired IFN-γ Production
Q40047869Regulatory T cells impede acute and long-term immunity to blood-stage malaria through CTLA-4.
Q93157505Safety and tolerance of lymph node biopsies from chronic HIV-1 volunteers in rural Tanzania
Q37720375Single-cell RNA-seq and computational analysis using temporal mixture modelling resolves Th1/Tfh fate bifurcation in malaria
Q92060086Structure and function of the immune system in the spleen
Q33792922Successive annual influenza vaccination induces a recurrent oligoclonotypic memory response in circulating T follicular helper cells
Q92802893T cell-mediated immunity to malaria
Q38682341T follicular helper cells regulate the activation of B lymphocytes and antibody production during Plasmodium vivax infection.
Q55187093Tfh1 Cells in Germinal Centers During Chronic HIV/SIV Infection.
Q88473114Th1-like Plasmodium-Specific Memory CD4+ T Cells Support Humoral Immunity
Q47315531Th1-like Plasmodium-Specific Memory CD4+ T Cells Support Humoral Immunity
Q104617066Th2-like T Follicular Helper Cells Promote Functional Antibody Production during Plasmodium falciparum Infection
Q64093204The Differentiation of Human Tonsil B Cells With the Phenotypic and Functional Characteristics of T-bet+ Atypical Memory B Cells in Malaria
Q39027956The Impact of Established Immunoregulatory Networks on Vaccine Efficacy and the Development of Immunity to Malaria.
Q98465723The Impact of Malaria Parasites on Dendritic Cell-T Cell Interaction
Q64252919The Role of IL-10 in Malaria: A Double Edged Sword
Q64102236The Transcription Factor T-Bet Is Required for Optimal Type I Follicular Helper T Cell Maintenance During Acute Viral Infection
Q60954894To B or Not to B: Understanding B Cell Responses in the Development of Malaria Infection
Q90721748Transcriptional Modulation of the Host Immunity Mediated by Cytokines and Transcriptional Factors in Plasmodium falciparum-Infected Patients of North-East India
Q100526329Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory
Q28554673Type I Interferons Induce T Regulatory 1 Responses and Restrict Humoral Immunity during Experimental Malaria
Q100724843Understanding vaccine-elicited protective immunity against pre-erythrocytic stage malaria in endemic regions
Q58572524γδ T Cells in Antimalarial Immunity: New Insights Into Their Diverse Functions in Protection and Tolerance

Search more.