Regulation of synaptic activity by snapin-mediated endolysosomal transport and sorting

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Regulation of synaptic activity by snapin-mediated endolysosomal transport and sorting is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.15252/EMBJ.201591125
P8608Fatcat IDrelease_msjs43t3zvdvxlrreusmt5rwfe
P932PMC publication ID4551352
P698PubMed publication ID26108535

P2093author name stringZu-Hang Sheng
Jerome Di Giovanni
P2860cites workSnapin: a SNARE-associated protein implicated in synaptic transmissionQ22009155
The schizophrenia susceptibility factor dysbindin and its associated complex sort cargoes from cell bodies to the synapseQ24293250
Assembly and architecture of biogenesis of lysosome-related organelles complex-1 (BLOC-1).Q24300804
Developmental refinement of vesicle cycling at Schaffer collateral synapsesQ45210560
Blocking endocytosis enhances short-term synaptic depression under conditions of normal availability of vesiclesQ46227771
Reluctant vesicles contribute to the total readily releasable pool in glutamatergic hippocampal neurons.Q46437156
Quantitative ultrastructural analysis of hippocampal excitatory synapses.Q46681133
Nanodomain coupling between Ca2+ channels and Ca2+ sensors promotes fast and efficient transmitter release at a cortical GABAergic synapseQ46730437
Constitutive sharing of recycling synaptic vesicles between presynaptic boutonsQ46931398
Endocytic structures and synaptic vesicle recycling at a central synapse in awake ratsQ48378968
Dysbindin deficiency in sandy mice causes reduction of snapin and displays behaviors related to schizophreniaQ48935967
Snapin accelerates exocytosis at low intracellular calcium concentration in mouse chromaffin cells.Q50946466
The neural cell adhesion molecule promotes maturation of the presynaptic endocytotic machinery by switching synaptic vesicle recycling from adaptor protein 3 (AP-3)- to AP-2-dependent mechanisms.Q51751503
Effects of PKA-mediated phosphorylation of Snapin on synaptic transmission in cultured hippocampal neurons.Q54504919
Synaptotagmin has an essential function in synaptic vesicle positioning for synchronous release in addition to its role as a calcium sensorQ64375154
Inhibition of neurotransmission by peptides containing the synaptic protein interaction site of N-type Ca2+ channelsQ71728596
Presynaptic enhancement of inhibitory synaptic transmission by protein kinases A and C in the rat hippocampus in vitroQ72575533
Alterations in transmission, vesicle dynamics, and transmitter release machinery at NCAM-deficient neuromuscular junctionsQ77334872
Dysbindin-1 is a synaptic and microtubular protein that binds brain snapinQ24303507
Identification of snapin and three novel proteins (BLOS1, BLOS2, and BLOS3/reduced pigmentation) as subunits of biogenesis of lysosome-related organelles complex-1 (BLOC-1)Q24337584
BLOC-1 is required for cargo-specific sorting from vacuolar early endosomes toward lysosome-related organellesQ24337651
Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophreniaQ24612644
The schizophrenia susceptibility gene dysbindin controls synaptic homeostasisQ24632783
Neurotransmitter release: the last millisecond in the life of a synaptic vesicleQ26269845
RIM determines Ca²+ channel density and vesicle docking at the presynaptic active zoneQ26269881
RIM proteins tether Ca2+ channels to presynaptic active zones via a direct PDZ-domain interactionQ26269921
Synaptic vesicle recycling: steps and principlesQ26825177
Axonal autophagosomes recruit dynein for retrograde transport through fusion with late endosomesQ27310389
BORC, a multisubunit complex that regulates lysosome positioning.Q27314810
The BLOC-1 complex promotes endosomal maturation by recruiting the Rab5 GTPase-activating protein Msb3.Q27940067
Phosphorylation of Snapin by PKA modulates its interaction with the SNARE complexQ28210000
Regulation of synaptophysin degradation by mammalian homologues of seven in absentiaQ28215219
Molecular anatomy of a trafficking organelleQ28274481
SCRAPPER-dependent ubiquitination of active zone protein RIM1 regulates synaptic vesicle releaseQ28505380
Snapin facilitates the synchronization of synaptic vesicle fusionQ28508747
Hermansky-Pudlak protein complexes, AP-3 and BLOC-1, differentially regulate presynaptic composition in the striatum and hippocampusQ28513167
BLOC-1 interacts with BLOC-2 and the AP-3 complex to facilitate protein trafficking on endosomesQ28513739
BLOC-1 complex deficiency alters the targeting of adaptor protein complex-3 cargoesQ28567313
A function for the AP3 coat complex in synaptic vesicle formation from endosomesQ28567917
Rim is a putative Rab3 effector in regulating synaptic-vesicle fusionQ28575529
Synaptic vesicle recycling at CNS snapses without AP-2Q28577663
DTNBP1, a schizophrenia susceptibility gene, affects kinetics of transmitter releaseQ28586199
Snapin-Regulated Late Endosomal Transport Is Critical for Efficient Autophagy-Lysosomal Function in NeuronsQ28592995
Roles of BLOC-1 and adaptor protein-3 complexes in cargo sorting to synaptic vesiclesQ28594620
SNAREs--engines for membrane fusionQ29547230
Definition of the readily releasable pool of vesicles at hippocampal synapsesQ29620402
Mutation of Ser-50 and Cys-66 in Snapin modulates protein structure and stability.Q30414930
Endosomal sorting of readily releasable synaptic vesiclesQ30497264
An expanded palette of genetically encoded Ca²⁺ indicatorsQ30533809
Clathrin regenerates synaptic vesicles from endosomes.Q30614584
The coupling between synaptic vesicles and Ca2+ channels determines fast neurotransmitter releaseQ33273491
How does synaptotagmin trigger neurotransmitter release?Q33345212
Synaptic vesicle poolsQ33983958
Optical mapping of release properties in synapsesQ34085810
Evidence for recycling of synaptic vesicle membrane during transmitter release at the frog neuromuscular junctionQ34207383
Clathrin/AP-2 mediate synaptic vesicle reformation from endosome-like vacuoles but are not essential for membrane retrieval at central synapses.Q34423567
Reduced synaptic vesicle protein degradation at lysosomes curbs TBC1D24/sky-induced neurodegenerationQ34566701
Distinct endocytic pathways control the rate and extent of synaptic vesicle protein recyclingQ34568799
Do different endocytic pathways make different synaptic vesicles?Q34621292
Rab3-GAP controls the progression of synaptic homeostasis at a late stage of vesicle releaseQ34688291
Synaptic vesicles retain their identity through the endocytic cycleQ34746833
Loss of AP-3 function affects spontaneous and evoked release at hippocampal mossy fiber synapsesQ35133914
A small pool of vesicles maintains synaptic activity in vivoQ35345585
Concurrent imaging of synaptic vesicle recycling and calcium dynamicsQ35505880
The role of Snapin in neurosecretion: snapin knock-out mice exhibit impaired calcium-dependent exocytosis of large dense-core vesicles in chromaffin cellsQ35647623
Lysosomal proteolysis inhibition selectively disrupts axonal transport of degradative organelles and causes an Alzheimer's-like axonal dystrophyQ35955959
Snapin is critical for presynaptic homeostatic plasticityQ36091712
The synaptic vesicle cycle: a single vesicle budding step involving clathrin and dynaminQ36237077
Synaptic vesicle reuse and its implicationsQ36361004
Proteasome inhibition triggers activity-dependent increase in the size of the recycling vesicle pool in cultured hippocampal neuronsQ37149682
Presynaptic membrane retrieval and endosome biology: defining molecularly heterogeneous synaptic vesiclesQ37197478
Ultrafast endocytosis at mouse hippocampal synapses.Q37642826
Readily releasable vesicles recycle at the active zone of hippocampal synapsesQ37701997
Molecular organization and plasticity of the cytomatrix at the active zoneQ37949766
Synaptic vesicle generation from central nerve terminal endosomesQ38262876
Clathrin-mediated endocytosis is the dominant mechanism of vesicle retrieval at hippocampal synapses.Q39751968
Loss of skywalker reveals synaptic endosomes as sorting stations for synaptic vesicle proteinsQ39754179
Increased transmitter release at excitatory synapses produced by direct activation of adenylate cyclase in rat hippocampal slices.Q41660380
A vesicle superpool spans multiple presynaptic terminals in hippocampal neurons.Q41786614
The role of non-canonical SNAREs in synaptic vesicle recyclingQ41829974
CDK5 serves as a major control point in neurotransmitter release.Q41862687
RIM-binding protein links synaptic homeostasis to the stabilization and replenishment of high release probability vesiclesQ41891455
A preferentially segregated recycling vesicle pool of limited size supports neurotransmission in native central synapsesQ42022259
High- and low-mobility stages in the synaptic vesicle cycleQ42125696
Synaptic vesicle pools: an updateQ42140979
v-SNARE composition distinguishes synaptic vesicle pools.Q42142233
Neuronal deficiency of presenilin 1 inhibits amyloid plaque formation and corrects hippocampal long-term potentiation but not a cognitive defect of amyloid precursor protein [V717I] transgenic mice.Q42675168
cAMP Modulates Intracellular Ca2+ Sensitivity of Fast-Releasing Synaptic Vesicles at the Calyx of Held SynapseQ42879231
Direct interactions between C. elegans RAB-3 and Rim provide a mechanism to target vesicles to the presynaptic densityQ43241214
Regulation of presynaptic neurotransmission by macroautophagyQ43242957
Rim1 and rabphilin-3 bind Rab3-GTP by composite determinants partially related through N-terminal alpha -helix motifsQ43657454
Small-scale isolation of synaptic vesicles from mammalian brainQ44391903
The ubiquitin proteasome system acutely regulates presynaptic protein turnover and synaptic efficacyQ44461744
P4510describes a project that usesImageJQ1659584
P433issue15
P407language of work or nameEnglishQ1860
P304page(s)2059-2077
P577publication date2015-06-24
P1433published inThe EMBO JournalQ1278554
P1476titleRegulation of synaptic activity by snapin-mediated endolysosomal transport and sorting
P478volume34

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cites work (P2860)
Q42092040AP-1/σ1A and AP-1/σ1B adaptor-proteins differentially regulate neuronal early endosome maturation via the Rab5/Vps34-pathway
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Q47578979Overexpression of cypin alters dendrite morphology, single neuron activity, and network properties via distinct mechanisms
Q39377253Recent insights on principles of synaptic protein degradation
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Q43266355Safeguards of Neurotransmission: Endocytic Adaptors as Regulators of Synaptic Vesicle Composition and Function
Q49795603Soluble Aβ1-42 increases the heterogeneity in synaptic vesicle pool size among synapses by suppressing intersynaptic vesicle sharing
Q47622230Structural and Functional Characterization of the Interaction of Snapin with the Dopamine Transporter: Differential Modulation of Psychostimulant Actions.
Q37490360The Proteome of BLOC-1 Genetic Defects Identifies the Arp2/3 Actin Polymerization Complex to Function Downstream of the Schizophrenia Susceptibility Factor Dysbindin at the Synapse
Q100455194The cross-talk of energy sensing and mitochondrial anchoring sustains synaptic efficacy by maintaining presynaptic metabolism
Q64039609The road to LROs: insights into lysosome-related organelles from Hermansky-Pudlak syndrome and other rare diseases
Q36156512miR-27b shapes the presynaptic transcriptome and influences neurotransmission by silencing the polycomb group protein Bmi1

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