Explicit hypoxia targeting with tumor suppression by creating an "obligate" anaerobic Salmonella Typhimurium strain

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Explicit hypoxia targeting with tumor suppression by creating an "obligate" anaerobic Salmonella Typhimurium strain is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1012259497
P356DOI10.1038/SREP00436
P932PMC publication ID3365283
P698PubMed publication ID22666539
P5875ResearchGate publication ID225184828

P50authorYuen Kwok-yungQ8060280
Lei-Han TangQ60544483
Lei ShiQ92859608
P2093author name stringJian-Dong Huang
Bin Yu
David K Smith
Bo-Jian Zheng
Mei Yang
Xuefei Li
Erwei Song
Qinqin Jiang
Yandan Yao
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Genetically engineered Salmonella typhimurium as an imageable therapeutic probe for cancerQ39760012
Attenuated Salmonella targets prodrug activating enzyme carboxypeptidase G2 to mouse melanoma and human breast and colon carcinomas for effective suicide gene therapyQ39966345
Oral delivery of tumor-targeting Salmonella for cancer therapy in murine tumor modelsQ40133689
Salmonella typhimurium lacking ribose chemoreceptors localize in tumor quiescence and induce apoptosisQ40149322
Remote control of tumour-targeted Salmonella enterica serovar Typhimurium by the use of L-arabinose as inducer of bacterial gene expression in vivoQ40171422
Salmonella typhimurium specifically chemotax and proliferate in heterogeneous tumor tissue in vitroQ40318166
A method to generate recombinant Salmonella typhi Ty21a strains expressing multiple heterologous genes using an improved recombineering strategyQ40323887
ppGpp-dependent stationary phase induction of genes on Salmonella pathogenicity island 1.Q40552048
Continuous intravenous administration of live genetically modified salmonella typhimurium in patients with metastatic melanomaQ43161957
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Targeted therapy with a Salmonella typhimurium leucine-arginine auxotroph cures orthotopic human breast tumors in nude miceQ43677697
Anticancer efficacy of systemically delivered anaerobic bacteria as gene therapy vectors targeting tumor hypoxia/necrosisQ43918986
Genetically engineered Bifidobacterium longum for tumor-targeting enzyme-prodrug therapy of autochthonous mammary tumors in ratsQ45859551
Influence of the environment on the [4Fe-4S]2+ to [2Fe-2S]2+ cluster switch in the transcriptional regulator FNR.Q46814622
Lipid A mutant Salmonella with suppressed virulence and TNFalpha induction retain tumor-targeting in vivoQ47992263
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A set of recombineering plasmids for gram-negative bacteriaQ50080127
Sparse initial entrapment of systemically injected Salmonella typhimurium leads to heterogeneous accumulation within tumorsQ50102730
Biodistribution and genetic stability of the novel antitumor agent VNP20009, a genetically modified strain of Salmonella typhimuriumQ50120814
Tumor-targeted Salmonella as a novel anticancer vectorQ50133173
Combination bacteriolytic therapy for the treatment of experimental tumorsQ24555050
Translational regulation of gene expression by an anaerobically induced small non-coding RNA in Escherichia coliQ24634637
Bacterial therapies: completing the cancer treatment toolboxQ24646711
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Cancer metastasis directly eradicated by targeted therapy with a modified Salmonella typhimuriumQ30491729
Phase I study of the intravenous administration of attenuated Salmonella typhimurium to patients with metastatic melanomaQ33340438
Tumor invasion of Salmonella enterica serovar Typhimurium is accompanied by strong hemorrhage promoted by TNF-alphaQ33495169
Tumor-targeting bacterial therapy with amino acid auxotrophs of GFP-expressing Salmonella typhimuriumQ33756746
Bifidobacterium longum as a delivery system for cancer gene therapy: selective localization and growth in hypoxic tumorsQ33898615
High-throughput screening for salmonella avirulent mutants that retain targeting of solid tumorsQ33920984
Monotherapy with a tumor-targeting mutant of S. typhimurium inhibits liver metastasis in a mouse model of pancreatic cancerQ33925546
In vivo expression technology strategies: valuable tools for biotechnology.Q34056559
Bacteria as tumour-targeting vectorsQ35215803
Monotherapy with a tumor-targeting mutant of Salmonella typhimurium cures orthotopic metastatic mouse models of human prostate cancerQ35840470
Tumor hypoxia and cancer progression.Q36185821
Clostridium spores as anti-tumour agents.Q36405753
Clostridial spores as live 'Trojan horse' vectors for cancer gene therapy: comparison with viral delivery systems.Q36495546
The use of clostridial spores for cancer treatment.Q36565145
Repeated cycles of Clostridium-directed enzyme prodrug therapy result in sustained antitumour effects in vivoQ36611812
Facultative or obligate anaerobic bacteria have the potential for multimodality therapy of solid tumoursQ36656933
Regulated programmed lysis of recombinant Salmonella in host tissues to release protective antigens and confer biological containmentQ36756869
Optimized clostridium-directed enzyme prodrug therapy improves the antitumor activity of the novel DNA cross-linking agent PR-104.Q37001301
Salmonella-allies in the fight against cancerQ37762990
P275copyright licenseCreative Commons Attribution-NonCommercial-ShareAlike 3.0 UnportedQ15643954
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjecthypoxiaQ105688
Salmonella TyphimuriumQ166491
P304page(s)436
P577publication date2012-06-01
P1433published inScientific ReportsQ2261792
P1476titleExplicit hypoxia targeting with tumor suppression by creating an "obligate" anaerobic Salmonella Typhimurium strain
P478volume2

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cites work (P2860)
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