Evolution of coreceptor utilization to escape CCR5 antagonist therapy.

scientific article

Evolution of coreceptor utilization to escape CCR5 antagonist therapy. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.VIROL.2016.04.010
P932PMC publication ID4913893
P698PubMed publication ID27128349

P50authorXiang GaoQ89334045
Makedonka MitrevaQ28805278
P2093author name stringJie Zhang
John Martin
Zheng Chen
Lee Ratner
Daniel Kuritzkes
Bruce Rosa
Timothy Henrich
P2860cites workStructures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonistsQ24619974
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Deep sequencing to infer HIV-1 co-receptor usage: application to three clinical trials of maraviroc in treatment-experienced patientsQ41991922
Fitness valleys constrain HIV-1's adaptation to its secondary chemokine coreceptor.Q42239239
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Mutations in gp41 are correlated with coreceptor tropism but do not improve prediction methods substantiallyQ51570780
Reducing chimera formation during PCR amplification to ensure accurate genotypingQ54411775
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Phase 2 study of the safety and efficacy of vicriviroc, a CCR5 inhibitor, in HIV-1-Infected, treatment-experienced patients: AIDS clinical trials group 5211Q80480588
Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cellsQ28288205
Reconstructing the Dynamics of HIV Evolution within Hosts from Serial Deep Sequence DataQ29394572
Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytesQ29619514
HIV-1 tropism dynamics and phylogenetic analysis from longitudinal ultra-deep sequencing data of CCR5- and CXCR4-using variantsQ30836893
Quantitative deep sequencing reveals dynamic HIV-1 escape and large population shifts during CCR5 antagonist therapy in vivoQ33455862
Accurate and efficient gp120 V3 loop structure based models for the determination of HIV-1 co-receptor usageQ33711003
Comparative determination of HIV-1 co-receptor tropism by Enhanced Sensitivity Trofile, gp120 V3-loop RNA and DNA genotypingQ34008448
Human immunodeficiency virus type 1 coreceptor switching: V1/V2 gain-of-fitness mutations compensate for V3 loss-of-fitness mutationsQ34301803
Use of four next-generation sequencing platforms to determine HIV-1 coreceptor tropismQ34482589
HIV-1 coreceptors and their inhibitorsQ34506596
A pièce de resistance: how HIV-1 escapes small molecule CCR5 inhibitorsQ34606129
Structure and immune recognition of trimeric pre-fusion HIV-1 Env.Q35142291
Predicting HIV-1 coreceptor usage with sequence analysis.Q35183379
Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruptionQ35190018
HIV-1 integration landscape during latent and active infectionQ35211469
Covariance of charged amino acids at positions 322 and 440 of HIV-1 Env contributes to coreceptor specificity of subtype B viruses, and can be used to improve the performance of V3 sequence-based coreceptor usage prediction algorithmsQ35330357
HIV-1 Coreceptor Usage Assessment by Ultra-Deep Pyrosequencing and Response to MaravirocQ35662019
Imperfect drug penetration leads to spatial monotherapy and rapid evolution of multidrug resistanceQ35699612
High throughput functional analysis of HIV-1 env genes without cloningQ35940070
HIV-1 gp120 V3 loop for structure-based drug designQ36296646
Change in coreceptor use correlates with disease progression in HIV-1--infected individualsQ36376800
Deciphering human immunodeficiency virus type 1 transmission and early envelope diversification by single-genome amplification and sequencingQ36540055
The implications of patterns in HIV diversity for neutralizing antibody induction and susceptibility.Q37667754
Coreceptors and HIV-1 pathogenesisQ37824291
Adhesion and fusion efficiencies of human immunodeficiency virus type 1 (HIV-1) surface proteinsQ39075099
Multiple extracellular domains of CCR-5 contribute to human immunodeficiency virus type 1 entry and fusion.Q39355095
The second extracellular loop of CCR5 is the major determinant of ligand specificity.Q39427062
A critical site in the core of the CCR5 chemokine receptor required for binding and infectivity of human immunodeficiency virus type 1.Q39460971
Structure-Guided Redesign Increases the Propensity of HIV Env To Generate Highly Stable Soluble TrimersQ39602726
Evidence for Common Structural Determinants of Human Immunodeficiency Virus Type 1 Coreceptor Activity Provided through Functional Analysis of CCR5/CXCR4 Chimeric CoreceptorsQ39605336
Identification of the optimal DC-SIGN binding site on human immunodeficiency virus type 1 gp120.Q40128614
Structural basis for the interaction of CCR5 with a small molecule, functionally selective CCR5 agonistQ40241635
Macrophage tropism determinants of human immunodeficiency virus type 1 in vivoQ40308974
Improved coreceptor usage prediction and genotypic monitoring of R5-to-X4 transition by motif analysis of human immunodeficiency virus type 1 env V3 loop sequencesQ40344458
P407language of work or nameEnglishQ1860
P304page(s)198-214
P577publication date2016-04-26
P1433published inVirologyQ7934867
P1476titleEvolution of coreceptor utilization to escape CCR5 antagonist therapy
P478volume494

Reverse relations

cites work (P2860)
Q92715332CCR5 status and metastatic progression in colorectal cancer
Q91760681V1 and V2 Domains of HIV Envelope Contribute to CCR5 Antagonist Resistance

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