CXCR4/CXCL12 axis promotes VEGF-mediated tumor angiogenesis through Akt signaling pathway

scientific article

CXCR4/CXCL12 axis promotes VEGF-mediated tumor angiogenesis through Akt signaling pathway is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.BBRC.2007.05.182
P932PMC publication ID1986788
P698PubMed publication ID17559806
P5875ResearchGate publication ID6276775

P2093author name stringSeunghee Kang
Hyunsuk Shim
Ke Liang
Zhongxing Liang
Younghyoun Yoon
Joann Brooks
Margaret Willard
P2860cites workInvolvement of chemokine receptors in breast cancer metastasisQ24290909
Hypoxia-inducible factor-1 mediates activation of cultured vascular endothelial cells by inducing multiple angiogenic factorsQ24320033
VEGF overexpression in clinically localized prostate tumors and neuropilin-1 overexpression in metastatic formsQ28141270
Tumorigenesis and the angiogenic switchQ29619849
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancerQ29622818
VEGF and the quest for tumour angiogenesis factorsQ34932327
Silencing of CXCR4 blocks breast cancer metastasisQ37074006
Sp1 is involved in Akt-mediated induction of VEGF expression through an HIF-1-independent mechanism.Q37594844
Hypoxia inducible factor-1alpha is increased in ischemic retina: temporal and spatial correlation with VEGF expressionQ38329502
The von Hippel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular endothelial growth factor promoter activityQ40023447
Lower expression of CXCR4 in lymph node metastases than in primary breast cancers: potential regulation by ligand-dependent degradation and HIF-1alphaQ40271040
Activated Neu/ErbB-2 induces expression of the vascular endothelial growth factor gene by functional activation of the transcription factor Sp 1.Q40526897
Inhibition of breast cancer metastasis by selective synthetic polypeptide against CXCR4.Q40543795
Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasisQ40548697
Akt and hypoxia-inducible factor-1 independently enhance tumor growth and angiogenesis.Q40554412
Hypoxia-inducible factor-1-independent regulation of vascular endothelial growth factor by hypoxia in colon cancer.Q40583161
The SDF-1-CXCR4 axis stimulates VEGF secretion and activates integrins but does not affect proliferation and survival in lymphohematopoietic cells.Q40780948
Normoxic and hypoxic regulation of vascular endothelial growth factor (VEGF) by astrocytoma cells is mediated by Ras.Q42818347
Evidence for a role of p38 kinase in hypoxia-inducible factor 1-independent induction of vascular endothelial growth factor expression by sodium arseniteQ44249791
Simultaneously targeting epidermal growth factor receptor tyrosine kinase and cyclooxygenase-2, an efficient approach to inhibition of squamous cell carcinoma of the head and neckQ45050425
Levels of soluble vascular endothelial growth factor (VEGF) receptor 1 in astrocytic tumors and its relation to malignancy, vascularity, and VEGF-A.Q48342270
Endothelin-1 induces vascular endothelial growth factor by increasing hypoxia-inducible factor-1alpha in ovarian carcinoma cells.Q51716343
The mRNA expression of cyclo-oxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF) in human breast cancer.Q53387393
Epidermal growth factor receptor gene expression in estrogen receptor-positive and negative human breast cancer cell linesQ68839289
Building better vasculatureQ74582167
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectangiogenesisQ539568
tumor angiogenesisQ110495869
P304page(s)716-722
P577publication date2007-06-04
P1433published inBiochemical and Biophysical Research CommunicationsQ864228
P1476titleCXCR4/CXCL12 axis promotes VEGF-mediated tumor angiogenesis through Akt signaling pathway
P478volume359

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