Sapap3 deletion anomalously activates short-term endocannabinoid-mediated synaptic plasticity

scientific article

Sapap3 deletion anomalously activates short-term endocannabinoid-mediated synaptic plasticity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.1701-11.2011
P932PMC publication ID3367431
P698PubMed publication ID21715621

P50authorJonathan T TingQ79447898
P2093author name stringMeng Chen
Guoping Feng
Nicole Calakos
Yehong Wan
Kristen Ade
P2860cites workAssociation of synapse-associated protein 90/ postsynaptic density-95-associated protein (SAPAP) with neurofilamentsQ22253862
A functional role of postsynaptic density-95-guanylate kinase-associated protein complex in regulating Shank assembly and stability to synapsesQ24307991
Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disordersQ24337114
Altered synaptic plasticity in a mouse model of fragile X mental retardationQ24530695
Endocannabinoid-mediated long-term plasticity requires cAMP/PKA signaling and RIM1alphaQ24564778
Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice.Q24648260
GKAP, a novel synaptic protein that interacts with the guanylate kinase-like domain of the PSD-95/SAP90 family of channel clustering moleculesQ24681609
Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteinsQ28141190
Proline-rich synapse-associated proteins ProSAP1 and ProSAP2 interact with synaptic proteins of the SAPAP/GKAP familyQ28145992
Synapse-associated protein-97 isoform-specific regulation of surface AMPA receptors and synaptic function in cultured neuronsQ28178909
Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein HomerQ28202988
SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic densityQ28235849
Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout miceQ28343324
Differential mRNA expression and protein localization of the SAP90/PSD-95-associated proteins (SAPAPs) in the nervous system of the mouseQ28506673
Characterization of the role of microtubule-associated protein 1B in metabotropic glutamate receptor-mediated endocytosis of AMPA receptors in hippocampusQ28569108
The interaction of phospholipase C-beta3 with Shank2 regulates mGluR-mediated calcium signalQ28574773
Distinct spatiotemporal expression of SAPAP transcripts in the developing rat brain: a novel dendritically localized mRNAQ28574872
Dynamin 3 is a component of the postsynapse, where it interacts with mGluR5 and HomerQ28581004
Postsynaptic positioning of endocytic zones and AMPA receptor cycling by physical coupling of dynamin-3 to HomerQ28583461
The mGluR theory of fragile X mental retardationQ29615060
PDZ domain proteins of synapsesQ29616399
A gene expression atlas of the central nervous system based on bacterial artificial chromosomesQ29617753
Regulation of dendritic spine morphology and synaptic function by Shank and HomerQ30014842
SLM Microscopy: Scanless Two-Photon Imaging and Photostimulation with Spatial Light ModulatorsQ30485339
Characterization of a range of fura dyes with two-photon excitationQ30751700
Discovery of positive allosteric modulators for the metabotropic glutamate receptor subtype 5 from a series of N-(1,3-diphenyl-1H- pyrazol-5-yl)benzamides that potentiate receptor function in vivoQ30842826
Laminar organization of the NMDA receptor complex within the postsynaptic density.Q31840072
Homer 1a gates the induction mechanism for endocannabinoid-mediated synaptic plasticityQ33744346
Endocytic trafficking and recycling maintain a pool of mobile surface AMPA receptors required for synaptic potentiationQ33761839
Reduction in endocannabinoid tone is a homeostatic mechanism for specific inhibitory synapsesQ33814760
Enhanced endocannabinoid signaling elevates neuronal excitability in fragile X syndromeQ34003224
The movement of N-arachidonoylethanolamine (anandamide) across cellular membranesQ34098988
Activation of group I mGluRs is necessary for induction of long-term depression at striatal synapsesQ34100802
Endocannabinoid signaling in the brainQ34125520
A novel selective positive allosteric modulator of metabotropic glutamate receptor subtype 5 has in vivo activity and antipsychotic-like effects in rat behavioral modelsQ34377770
Characterization of guanylate kinase-associated protein, a postsynaptic density protein at excitatory synapses that interacts directly with postsynaptic density-95/synapse-associated protein 90.Q34432369
Functional role of high-affinity anandamide transport, as revealed by selective inhibitionQ34436019
Dopaminergic control of corticostriatal long-term synaptic depression in medium spiny neurons is mediated by cholinergic interneurons.Q34521936
Frequency-specific and D2 receptor-mediated inhibition of glutamate release by retrograde endocannabinoid signalingQ34650334
Abnormal mGlu 5 receptor/endocannabinoid coupling in mice lacking FMRP and BC1 RNA.Q34660995
Dichotomous anatomical properties of adult striatal medium spiny neuronsQ35607269
Endocannabinoid signaling and long-term synaptic plasticity.Q35679432
Homer 1a uncouples metabotropic glutamate receptor 5 from postsynaptic effectorsQ35749646
Decreased probability of neurotransmitter release underlies striatal long-term depression and postnatal development of corticostriatal synapsesQ36054269
Retrograde endocannabinoid signaling at striatal synapses requires a regulated postsynaptic release stepQ36300113
Studies of anandamide accumulation inhibitors in cerebellar granule neurons: comparison to inhibition of fatty acid amide hydrolaseQ36470347
Metaplastic control of the endocannabinoid system at inhibitory synapses in hippocampus.Q36693029
Endocannabinoid-dependent plasticity at GABAergic and glutamatergic synapses in the striatum is regulated by synaptic activityQ37140712
Endocannabinoid-mediated control of synaptic transmissionQ37363621
Neurotransmitter roles in synaptic modulation, plasticity and learning in the dorsal striatumQ37680104
S6K1 phosphorylates and regulates fragile X mental retardation protein (FMRP) with the neuronal protein synthesis-dependent mammalian target of rapamycin (mTOR) signaling cascadeQ39627495
A key role for diacylglycerol lipase-alpha in metabotropic glutamate receptor-dependent endocannabinoid mobilization.Q40116679
Endocannabinoid-mediated short-term suppression of excitatory synaptic transmission to medium spiny neurons in the striatumQ42167436
Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease modelsQ42508054
Drd1a-tdTomato BAC transgenic mice for simultaneous visualization of medium spiny neurons in the direct and indirect pathways of the basal ganglia.Q42525723
Imaging action potentials with calcium indicatorsQ43164897
Presynaptic inhibition caused by retrograde signal from metabotropic glutamate to cannabinoid receptorsQ43715218
Metabotropic glutamate receptors drive the endocannabinoid system in hippocampus.Q43816494
Cooperative endocannabinoid production by neuronal depolarization and group I metabotropic glutamate receptor activationQ43936608
Long-term potentiation of mGluR1 activity by depolarization-induced Homer1a in mouse cerebellar Purkinje neuronsQ44373746
Differential electrophysiological properties of dopamine D1 and D2 receptor-containing striatal medium-sized spiny neuronsQ44463501
Disruption of endocannabinoid release and striatal long-term depression by postsynaptic blockade of endocannabinoid membrane transport.Q44770106
A single in vivo exposure to cocaine abolishes endocannabinoid-mediated long-term depression in the nucleus accumbens.Q45007590
Mechanisms for synapse specificity during striatal long-term depression.Q45937925
Dopamine modulation of state-dependent endocannabinoid release and long-term depression in the striatum.Q46279749
Key role of the postsynaptic density scaffold proteins Shank and Homer in the functional architecture of Ca2+ homeostasis at dendritic spines in hippocampal neurons.Q46472740
Post-receptor mechanisms underlying striatal long-term depression.Q51627778
Glutamate receptor anchoring proteins and the molecular organization of excitatory synapses.Q52571669
Metabotropic glutamate receptor-mediated presynaptic depression at corticostriatal synapses involves mGLuR2 or 3Q71870839
P433issue26
P407language of work or nameEnglishQ1860
P921main subjectsynaptic plasticityQ1551556
endocannabinoidsQ10483908
P304page(s)9563-9573
P577publication date2011-06-01
P1433published inJournal of NeuroscienceQ1709864
P1476titleSapap3 deletion anomalously activates short-term endocannabinoid-mediated synaptic plasticity
P478volume31

Reverse relations

cites work (P2860)
Q28082048A selective review of glutamate pharmacological therapy in obsessive-compulsive and related disorders
Q92710492Aberrant habit formation in the Sapap3-knockout mouse model of obsessive-compulsive disorder
Q27318286Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism.
Q28391134Autism-associated gene Dlgap2 mutant mice demonstrate exacerbated aggressive behaviors and orbitofrontal cortex deficits
Q38575839Autism: Oxytocin, serotonin, and social reward
Q92877976Cannabis use is associated with potentially heritable widespread changes in autism candidate gene DLGAP2 DNA methylation in sperm
Q92920694Cataloguing and Selection of mRNAs Localized to Dendrites in Neurons and Regulated by RNA-Binding Proteins in RNA Granules
Q35035766Changes in sensitivity of reward and motor behavior to dopaminergic, glutamatergic, and cholinergic drugs in a mouse model of fragile X syndrome
Q43121614Circuit-selective striatal synaptic dysfunction in the Sapap3 knockout mouse model of obsessive-compulsive disorder
Q58868596Contrasting actions of group I metabotropic glutamate receptors in distinct mouse striatal neurones
Q35828317Dopamine-dependent corticostriatal synaptic filtering regulates sensorimotor behavior
Q33877423Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and Autism
Q34304094Endocannabinoid signaling and synaptic function
Q38459136Gene expression profiling predicts pathways and genes associated with Parkinson's disease
Q38593120Genetic Manipulation of the Endocannabinoid System
Q38246625Genetic findings in obsessive-compulsive disorder connect to brain-derived neutrophic factor and mammalian target of rapamycin pathways: implications for drug development
Q34428744Genetic inhibition of CaMKII in dorsal striatal medium spiny neurons reduces functional excitatory synapses and enhances intrinsic excitability.
Q46461702Glutamate Genetics in Obsessive-Compulsive Disorder: A Review
Q30234294Hunger and Satiety Gauge Reward Sensitivity
Q36019618Impaired Ethanol-Induced Sensitization and Decreased Cannabinoid Receptor-1 in a Model of Posttraumatic Stress Disorder.
Q41634132Increased Metabotropic Glutamate Receptor 5 Signaling Underlies Obsessive-Compulsive Disorder-like Behavioral and Striatal Circuit Abnormalities in Mice
Q36249163Learning From Animal Models of Obsessive-Compulsive Disorder
Q41890579Mouse model of rare TOR1A variant found in sporadic focal dystonia impairs domains affected in DYT1 dystonia patients and animal models
Q42468408Muscarinic presynaptic modulation in GABAergic pallidal synapses of the rat.
Q35898012Neuroligin 1 modulates striatal glutamatergic neurotransmission in a pathway and NMDAR subunit-specific manner
Q30561087Optogenetic stimulation of lateral orbitofronto-striatal pathway suppresses compulsive behaviors
Q38442124Oxytocin: parallel processing in the social brain?
Q96681430Projection-specific deficits in synaptic transmission in adult Sapap3-knockout mice
Q49834838Role of Striatal Direct Pathway 2-Arachidonoylglycerol Signaling in Sociability and Repetitive Behavior
Q36329526Sapap3 deletion causes mGluR5-dependent silencing of AMPAR synapses
Q30376422Selective Disruption of Metabotropic Glutamate Receptor 5-Homer Interactions Mimics Phenotypes of Fragile X Syndrome in Mice.
Q38203028Synaptic basis of social dysfunction: a focus on postsynaptic proteins linking group-I mGluRs with AMPARs and NMDARs.
Q41611100The DLGAP family: neuronal expression, function and role in brain disorders
Q74878119The association of spinophilin with disks large-associated protein 3 (SAPAP3) is regulated by metabotropic glutamate receptor (mGluR) 5
Q43180212Utilizing GCaMP transgenic mice to monitor endogenous Gq/11-coupled receptors

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