Overexpression of cellular inhibitor of apoptosis protein 2 is an early event in the progression of pancreatic cancer

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Overexpression of cellular inhibitor of apoptosis protein 2 is an early event in the progression of pancreatic cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1136/JCP.2006.038257
P932PMC publication ID1994512
P698PubMed publication ID16775116
P5875ResearchGate publication ID7008805

P50authorHelmut FriessQ15453363
Irene EspositoQ65581417
Nathalia GieseQ87716518
P2093author name stringJörg Kleeff
Wilfried Roth
Peter Schirmacher
Frank Bergmann
Ivane Abiatari
Xined Shi
P2860cites workSuppression of apoptosis in mammalian cells by NAIP and a related family of IAP genesQ24315805
cIAP1 Localizes to the nuclear compartment and modulates the cell cycleQ24338725
Phase III trial of postoperative cisplatin, interferon alpha-2b, and 5-FU combined with external radiation treatment versus 5-FU alone for patients with resected pancreatic adenocarcinoma -- CapRI: study protocol [ISRCTN62866759]Q24792780
Apoptosis: targets in pancreatic cancerQ24800170
Genetic alterations in pancreatic carcinomaQ24801465
Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuliQ28116145
Expression of inhibitor of apoptosis proteins in small- and non-small-cell lung carcinoma cellsQ28202920
Anoikis mechanismsQ28215553
Expression of cIAP1, a target for 11q22 amplification, correlates with resistance of cervical cancers to radiotherapyQ28220281
The Survivin saga goes in vivoQ28360685
NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activationQ29618715
XIAP is related to the chemoresistance and inhibited its expression by RNA interference sensitize pancreatic carcinoma cells to chemotherapeuticsQ33240542
The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomasQ33862984
Pancreatic intraepithelial neoplasia: a new nomenclature and classification system for pancreatic duct lesionsQ34244725
Tenascin C and annexin II expression in the process of pancreatic carcinogenesis.Q34490284
A randomized trial of chemoradiotherapy and chemotherapy after resection of pancreatic cancerQ34546440
Adjuvant therapy in pancreatic cancer: historical and current perspectivesQ35110205
bax, but not bcl-2, influences the prognosis of human pancreatic cancerQ35352240
Tissue microarrays: a current medical research toolQ35771798
Reawakening the cellular death program in neoplasia through the therapeutic blockade of IAP functionQ36274969
Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB controlQ36580820
Nuclear and cytoplasmic expression of survivin in 67 surgically resected pancreatic cancer patients.Q36616034
The correlation between cytoplasmic overexpression of epidermal growth factor receptor and tumor aggressiveness: poor prognosis in patients with pancreatic ductal adenocarcinomaQ38447221
Multiple and synergistic deregulations of apoptosis-controlling genes in pancreatic carcinoma cellsQ38602933
The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspasesQ40341729
Introduction of a survivin gene-specific small inhibitory RNA inhibits growth of pancreatic cancer cellsQ40347589
Downregulation of survivin by siRNA diminishes radioresistance of pancreatic cancer cells.Q40375391
Nuclear shuttling and TRAF2-mediated retention in the cytoplasm regulate the subcellular localization of cIAP1 and cIAP2.Q40533310
Subcellular expression of c-IAP1 and c-IAP2 in colorectal cancers: relationships with clinicopathological features and prognosisQ40601815
Coexistence of high levels of apoptotic signaling and inhibitor of apoptosis proteins in human tumor cells: implication for cancer specific therapyQ40622056
Suppression of metastatic hemangiosarcoma by a parvovirus MVMp vector transducing the IP-10 chemokine into immunocompetent miceQ40737184
Frequency of K-ras mutations in pancreatic intraductal neoplasias associated with pancreatic ductal adenocarcinoma and chronic pancreatitis: a meta-analysisQ41460315
Cancer statistics, 2003.Q43729872
Relationship between activation of epidermal growth factor receptor and cell dissociation in pancreatic cancer.Q51822669
Assessment of IAP (inhibitor of apoptosis) proteins as predictors of response to chemotherapy in advanced non-small-cell lung cancer patients.Q52590107
ras Oncogene triggers up-regulation of cIAP2 and XIAP in intestinal epithelial cells: epidermal growth factor receptor-dependent and -independent mechanisms of ras-induced transformation.Q53355086
Identification of cIAP1 as a candidate target gene within an amplicon at 11q22 in esophageal squamous cell carcinomas.Q53395761
Effects and expression of TRAIL and its apoptosis-promoting receptors in human pancreatic cancer.Q54022571
Enhanced expression of Silencer of death domains (SODD/BAG-4) in pancreatic cancer.Q54052581
Bcl-2 expression in pancreas development and pancreatic cancer progressionQ58854740
Expression of survivin is correlated with cancer cell apoptosis and is involved in the development of human pancreatic duct cell tumorsQ74245159
Moderate activation of the apoptosis inhibitor bcl-xL worsens the prognosis in pancreatic cancerQ77709638
Curative resection is the single most important factor determining outcome in patients with pancreatic adenocarcinomaQ80040456
Expression and localization of inhibitor of apoptosis proteins in normal human tissuesQ81637512
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectpancreatic cancerQ212961
apoptotic processQ14599311
overexpressionQ61643320
P304page(s)885-895
P577publication date2006-06-14
P1433published inJournal of Clinical PathologyQ6294965
P1476titleOverexpression of cellular inhibitor of apoptosis protein 2 is an early event in the progression of pancreatic cancer
P478volume60

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cites work (P2860)
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Q43077403Translation of cIAP2 mRNA is mediated exclusively by a stress-modulated ribosome shunt