A Selective Novel Peroxisome Proliferator-Activated Receptor (PPAR)-α Antagonist Induces Apoptosis and Inhibits Proliferation of CLL Cells In Vitro and In Vivo

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A Selective Novel Peroxisome Proliferator-Activated Receptor (PPAR)-α Antagonist Induces Apoptosis and Inhibits Proliferation of CLL Cells In Vitro and In Vivo is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1068965770
P356DOI10.2119/MOLMED.2015.00139
P932PMC publication ID4559529
P698PubMed publication ID26070013
P5875ResearchGate publication ID278039323

P50authorDaniel S LorrainQ106171230
P2093author name stringDavid Spaner
Davorka Messmer
Nicholas Chiorazzi
Peppi Prasit
Karin Stebbins
Nicholas Stock
Austin Chen
Lucia Correa
Yalda Bravo
Geraldine Cabrera
Jason Jacintho
Kymmy Lorrain
Xiao Jie Yan
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The phosphoinositide 3′-kinase delta inhibitor, CAL-101, inhibits B-cell receptor signaling and chemokine networks in chronic lymphocytic leukemiaQ39722770
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Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growthQ34147708
Phosphatidylinositol 3-kinase-δ inhibitor CAL-101 shows promising preclinical activity in chronic lymphocytic leukemia by antagonizing intrinsic and extrinsic cellular survival signalsQ34184717
Inhibition of PPARα Induces Cell Cycle Arrest and Apoptosis, and Synergizes with Glycolysis Inhibition in Kidney Cancer CellsQ34948760
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Treatment of fludarabine-refractory chronic lymphocytic leukemiaQ34978317
A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the diseaseQ35029969
Enhanced outgrowth of EBV-transformed chronic lymphocytic leukemia B cells mediated by coculture with macrophage feeder cellsQ35777015
A metabolic prosurvival role for PML in breast cancer.Q36208566
Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipidsQ36895786
B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor, R406.Q37028635
Cancer metabolism: fatty acid oxidation in the limelightQ37155867
Molecular and cellular mechanisms of CLL: novel therapeutic approaches.Q37504699
Adipocyte is a non-trivial, dynamic partner of breast cancer cellsQ37939013
Targeting peroxisome proliferator-activated receptors (PPARs): development of modulators.Q37977108
Non-glucose metabolism in cancer cells—is it all in the fat?Q38019411
PPARα and fatty acid oxidation mediate glucocorticoid resistance in chronic lymphocytic leukemia.Q39132660
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P304page(s)410-419
P577publication date2015-06-09
P1433published inMolecular MedicineQ6895961
P1476titleA Selective Novel Peroxisome Proliferator-Activated Receptor (PPAR)-α Antagonist Induces Apoptosis and Inhibits Proliferation of CLL Cells In Vitro and In Vivo
P478volume21

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