| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1997PNAS...94.1878N |
| P356 | DOI | 10.1073/PNAS.94.5.1878 |
| P932 | PMC publication ID | 20011 |
| P698 | PubMed publication ID | 9050873 |
| P5875 | ResearchGate publication ID | 14160331 |
| P50 | author | Brad H Nelson | Q58140779 |
| P2093 | author name string | P D Greenberg | |
| B C McIntosh | |||
| B H Nelson | |||
| L L Rosencrans | |||
| P2860 | cites work | Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4 | Q24323130 |
| Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor | Q24323187 | ||
| Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor | Q24323232 | ||
| Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation | Q24567993 | ||
| Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15 | Q24595192 | ||
| JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region | Q24612039 | ||
| Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID | Q28241595 | ||
| Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits | Q28241606 | ||
| Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells | Q28244421 | ||
| The adapter protein Shc interacts with the interleukin-2 (IL-2) receptor upon IL-2 stimulation | Q28258982 | ||
| Cloning of the gamma chain of the human IL-2 receptor | Q28284261 | ||
| Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor | Q28288032 | ||
| Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID) | Q28296501 | ||
| Analysis of interleukin-2-dependent signal transduction through the Shc/Grb2 adapter pathway. Interleukin-2-dependent mitogenesis does not require Shc phosphorylation or receptor association | Q28610810 | ||
| Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: possible link with the c-myc induction pathway | Q28610817 | ||
| Evidence for a role for the phosphotyrosine-binding domain of Shc in interleukin 2 signaling | Q28610830 | ||
| Functional participation of the IL-2 receptor gamma chain in IL-7 receptor complexes | Q28647290 | ||
| The molecular role of the common gamma c subunit in signal transduction reveals functional asymmetry within multimeric cytokine receptor complexes | Q33611995 | ||
| Critical role of the interleukin 2 (IL-2) receptor gamma-chain-associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene induction | Q33921686 | ||
| Interleukin 2 signaling involves the phosphorylation of Stat proteins | Q34007160 | ||
| Signaling through the interleukin 2 receptor beta chain activates a STAT-5-like DNA-binding activity | Q34034959 | ||
| Interaction of the IL-2 receptor with the src-family kinase p56lck: identification of novel intermolecular association | Q34115915 | ||
| Activation of Stat5 by interleukin 2 requires a carboxyl-terminal region of the interleukin 2 receptor beta chain but is not essential for the proliferative signal transmission | Q34229092 | ||
| Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development. | Q34288951 | ||
| Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain. | Q34307135 | ||
| Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain. | Q34759631 | ||
| Physical association of JAK1 and JAK2 tyrosine kinases with the interleukin 2 receptor beta and gamma chains. | Q35625634 | ||
| PTP1D is a positive regulator of the prolactin signal leading to beta-casein promoter activation. | Q35842771 | ||
| Reconstitution of functional interleukin 2 receptor complexes on fibroblastoid cells: involvement of the cytoplasmic domain of the gamma chain in two distinct signaling pathways | Q36282522 | ||
| Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice | Q36364066 | ||
| The interleukin-2 receptor gamma chain maps to Xq13.1 and is mutated in X-linked severe combined immunodeficiency, SCIDX1. | Q36772827 | ||
| Characterization of critical residues in the cytoplasmic domain of the human interleukin-5 receptor alpha chain required for growth signal transduction | Q38293999 | ||
| An epidermal growth factor receptor/Jak2 tyrosine kinase domain chimera induces tyrosine phosphorylation of Stat5 and transduces a growth signal in hematopoietic cells | Q38354196 | ||
| A membrane-proximal region of the interleukin-2 receptor gamma c chain sufficient for Jak kinase activation and induction of proliferation in T cells. | Q40018055 | ||
| Ligand-induced assembly and activation of the gamma interferon receptor in intact cells | Q40019119 | ||
| Cytokine receptor signalling | Q40416594 | ||
| Cytokine signaling through nonreceptor protein tyrosine kinases | Q40506447 | ||
| Signaling mechanisms through cytokine receptors that share signal transducing receptor components | Q40540032 | ||
| Dimerization of cell surface receptors in signal transduction | Q40579106 | ||
| Dispensability of Jak1 tyrosine kinase for interleukin-2-induced cell growth signaling in a human T cell line | Q41196737 | ||
| Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the beta chain and non-tyrosine residues of the gamma c chain. | Q41294941 | ||
| Signal transduction by a CD16/CD7/Jak2 fusion protein | Q41313560 | ||
| Prevention of T cell anergy by signaling through the gamma c chain of the IL-2 receptor | Q41429389 | ||
| Interleukin 2-induced activation of JAK3: possible involvement in signal transduction for c-myc induction and cell proliferation | Q41442971 | ||
| Heterodimerization of the IL-2 receptor beta- and gamma-chain cytoplasmic domains is required for signalling | Q41466961 | ||
| Cytoplasmic domains of the interleukin-2 receptor beta and gamma chains mediate the signal for T-cell proliferation. | Q41466988 | ||
| A restricted cytoplasmic region of IL-2 receptor beta chain is essential for growth signal transduction but not for ligand binding and internalization | Q41759523 | ||
| Interleukin 2 (IL-2)-induced tyrosine phosphorylation of IL-2 receptor p75 | Q41973445 | ||
| Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. | Q42064178 | ||
| Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans | Q45874932 | ||
| Mammalian SH2-containing protein tyrosine phosphatases | Q48064947 | ||
| The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15. | Q50335906 | ||
| Developmental defects of lymphoid cells in Jak3 kinase-deficient mice. | Q52204302 | ||
| IL-2-induced signal transduction: involvement of tyrosine kinase and IL-2 receptor gamma chain | Q70277287 | ||
| Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3 | Q71542082 | ||
| Defective lymphoid development in mice lacking Jak3 | Q71542089 | ||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1878-1883 | |
| P577 | publication date | 1997-03-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Requirement for an initial signal from the membrane-proximal region of the interleukin 2 receptor gamma(c) chain for Janus kinase activation leading to T cell proliferation | |
| P478 | volume | 94 |
| Q33864732 | A model for assembly and activation of the GM-CSF, IL-3 and IL-5 receptors: insights from activated mutants of the common beta subunit |
| Q30176126 | A new tyrosine-phosphorylated 97-kDa adaptor protein mediates interleukin-2-induced association of SHP-2 with p85-phosphatidylinositol 3-kinase in human T lymphocytes |
| Q33964308 | Activation of the interleukin 2 receptor: a possible role for tyrosine phosphatases |
| Q28212401 | Alternate signalling pathways from the interleukin-2 receptor |
| Q40678150 | Anti-apoptotic signaling by the interleukin-2 receptor reveals a function for cytoplasmic tyrosine residues within the common gamma (gamma c) receptor subunit |
| Q45113910 | Biology of the interleukin-2 receptor |
| Q73388921 | Cloning and Characterization of Porcine CommonγChain Gene |
| Q38322454 | Critical role of the membrane-proximal, proline-rich motif of the interleukin-2 receptor gammac chain in the Jak3-independent signal transduction |
| Q37250038 | Differential requirement of the cytoplasmic subregions of gamma c chain in T cell development and function |
| Q40971179 | Differential substrate recognition capabilities of Janus family protein tyrosine kinases within the interleukin 2 receptor (IL2R) system: Jak3 as a potential molecular target for treatment of leukemias with a hyperactive Jak-Stat signaling machinery |
| Q34015840 | Enhanced signaling through the IL-2 receptor in CD8+ T cells regulated by antigen recognition results in preferential proliferation and expansion of responding CD8+ T cells rather than promotion of cell death |
| Q28115484 | Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activation |
| Q80455481 | IL-2Rbeta links IL-2R signaling with Foxp3 expression |
| Q38295031 | Identification of novel targets of immunosuppressive agents by cDNA-based microarray analysis |
| Q77470217 | Interferon-alpha inhibits Stat5 DNA-binding in IL-2 stimulated primary T-lymphocytes |
| Q33917765 | Interleukin-2 receptor downstream events in regulatory T cells: implications for the choice of immunosuppressive drug therapy |
| Q33888375 | Janus kinase 3 (Jak3) is essential for common cytokine receptor gamma chain (gamma(c))-dependent signaling: comparative analysis of gamma(c), Jak3, and gamma(c) and Jak3 double-deficient mice |
| Q77481930 | Recent advances in the understanding of interleukin-2 signal transduction |
| Q40653225 | Src Homology Region 2-Containing Protein Tyrosine Phosphatase-2 (SHP-2) Can Play a Direct Role in the Inhibitory Function of Killer Cell Ig-Like Receptors in Human NK Cells |
| Q28140287 | Stat5a and Stat5b: fraternal twins of signal transduction and transcriptional activation |
| Q40735322 | Studies with chimeric Mpl/JAK2 receptors indicate that both JAK2 and the membrane-proximal domain of Mpl are required for cellular proliferation |
| Q49085328 | The cell surface expression level of the human interleukin-5 receptor alpha subunit determines the agonistic/antagonistic balance of the human interleukin-5 E13Q mutein. |
| Q38607461 | The common γ-chain cytokine receptor: tricks-and-treats for T cells. |
| Q40995235 | The interleukin-4 receptor activates STAT5 by a mechanism that relies upon common gamma-chain |
| Q41587141 | The role of Jak3 in lymphoid development, activation, and signaling |
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