| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.1200/JCO.1992.10.5.839 |
| P953 | full work available at URL | http://intl.jco.org/cgi/content/abstract/10/5/839 |
| P698 | PubMed publication ID | 1569455 |
| P50 | author | Bruce D. Cheson | Q88248387 |
| P2093 | author name string | D. R. Parkinson | |
| M. A. Smith | |||
| M. A. Friedman | |||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 839-864 | |
| P577 | publication date | 1992-05-01 | |
| P1433 | published in | Journal of Clinical Oncology | Q400292 |
| P1476 | title | Retinoids in cancer therapy | |
| P478 | volume | 10 |
| Q73158692 | 13-cis-retinoic acid and alpha-interferon in advanced squamous cell cancer of the oesophagus |
| Q36397870 | 9-cis-retinoic acid inhibits activation-driven T-cell apoptosis: implications for retinoid X receptor involvement in thymocyte development |
| Q22010974 | A RA-dependent, tumour-growth suppressive transcription complex is the target of the PML-RARalpha and T18 oncoproteins |
| Q31079698 | A library construction of 2,5-disubstituted pyrrole compounds by using solid/solution-phase syntheses |
| Q40820999 | A mechanism of apoptosis induced by all-trans retinoic acid on adult T-cell leukemia cells: a possible involvement of the Tax/NF-kappaB signaling pathway |
| Q41429829 | A new class of retinoids with selective inhibition of AP-1 inhibits proliferation |
| Q40734744 | A novel mechanism of retinoic acid resistance in acute promyelocytic leukemia cells through a defective pathway in telomerase regulation. |
| Q40518875 | A novel retinoid, 4-[3,5-bis (trimethylsilyl) benzamido] benzoic acid (TAC-101), induces apoptosis of human ovarian carcinoma cells and shows potential as a new antitumor agent for clear cell adenocarcinoma |
| Q52991852 | A phase II pilot trial of 13-cis retinoic acid and interferon-alpha in patients with advanced pancreatic carcinoma. |
| Q54124954 | A phase II study of all-trans-retinoic acid plus cisplatin and etoposide in patients with extensive stage small cell lung carcinoma: an Eastern Cooperative Oncology Group Study. |
| Q41140320 | A systems approach to cancer therapy. (Antioncogenics + standard cytotoxics-->mechanism(s) of interaction). |
| Q37697226 | A transition in transcriptional activation by the glucocorticoid and retinoic acid receptors at the tumor stage of dermal fibrosarcoma development. |
| Q41418402 | Acquired immunodeficiency syndrome-associated Kaposi's sarcoma. Biology and management |
| Q47821155 | Acute promyelocytic leukemia as a model for cross-talk between interferon and retinoic acid pathways: from molecular biology to clinical applications. |
| Q33739256 | Acute promyelocytic leukemia: from treatment to genetics and back |
| Q73567750 | Adverse effects of highdose vitamin A during radiotherapy |
| Q42951411 | All-trans retinoic Acid regulates cx43 expression, gap junction communication and differentiation in primary lens epithelial cells |
| Q73265784 | All-trans retinoic acid and interferon-alpha-2a in patients with metastatic or recurrent carcinoma of the uterine cervix: clinical and pharmacokinetic studies. New York Gynecologic Oncology Group |
| Q36431663 | All-trans retinoic acid decreases susceptibility of a gastric cancer cell line to lymphokine-activated killer cytotoxicity |
| Q48634010 | All-trans retinoic acid in relapsing malignant gliomas: clinical and radiological stabilization associated with the appearance of intratumoral calcifications. |
| Q41735061 | All-trans-retinoic acid effects the growth, differentiation and apoptosis of normal human myeloid progenitors derived from purified CD34+ bone marrow cells |
| Q40883538 | All-trans-retinoic acid: a phase II Radiation Therapy Oncology Group study (RTOG 91-13) in patients with recurrent malignant astrocytoma |
| Q37423632 | Altered localization of retinoid X receptor alpha coincides with loss of retinoid responsiveness in human breast cancer MDA-MB-231 cells |
| Q74456027 | Altered metabolism of all-trans-retinoic acid in liposome-encapsulated form |
| Q74455093 | An Eastern Cooperative Oncology Group phase I trial of all-trans-retinoic acid and interferon-alpha: E2Y92 |
| Q31922478 | Analysis of the molecular genetics of acute promyelocytic leukemia in mouse models |
| Q34143378 | Antiproliferative effect of retinoid compounds on Kaposi's sarcoma cells |
| Q57980420 | Apoptosis of Human Neuroblastoma Cells Induced by Liposome-Encapsulated Fenretinide |
| Q40879102 | Bcl-2 accelerates retinoic acid-induced growth arrest and recovery in human gastric cancer cells |
| Q33842950 | Biomarkers and molecular epidemiology and chemoprevention of oral carcinogenesis |
| Q36159570 | Blocking activator protein-1 activity, but not activating retinoic acid response element, is required for the antitumor promotion effect of retinoic acid |
| Q67471902 | Case report: All‐trans retinoic acid, hyperleukocytosis, and marrow infarction |
| Q30444981 | Cellular distribution of retinoic acid receptor-alpha protein in serous adenocarcinomas of ovarian, tubal, and peritoneal origin: comparison with estrogen receptor status |
| Q43638349 | Chemoprevention of NMU-induced rat mammary carcinoma with the combination of melatonin and 9-cis-retinoic acid |
| Q35154604 | Chmp 1A is a mediator of the anti-proliferative effects of all-trans retinoic acid in human pancreatic cancer cells |
| Q44640574 | Clinical efficacy of all-trans retinoic acid for treating adult T cell leukemia |
| Q40651616 | Clinical progress in neuroblastoma |
| Q28145366 | Cloning and characterization of a novel retinoid-inducible gene 1(RIG1) deriving from human gastric cancer cells |
| Q30984828 | Cloning and expression of a novel nuclear matrix-associated protein that is regulated during the retinoic acid-induced neuronal differentiation |
| Q72187211 | Combination of highly purified human leukocyte interferon alpha and 13-cis-retinoic acid for the treatment of metastatic melanoma |
| Q53449097 | Current status of retinoids in chemoprevention of oral squamous cell carcinoma: an overview. |
| Q34569485 | Cyclin D1 and cancer development in laryngeal premalignancy patients |
| Q33279222 | Cytodifferentiation by retinoids, a novel therapeutic option in oncology: rational combinations with other therapeutic agents |
| Q72032394 | Determination of the retinobenzoic acid derivative Am580 in rat plasma by high-performance liquid chromatography |
| Q46448334 | Dichotomy of all-trans retinoic acid inducing signals for adult T-cell leukemia |
| Q40855700 | Diet as risk and therapy for cancer. |
| Q28378417 | Different agonist- and antagonist-induced conformational changes in retinoic acid receptors analyzed by protease mapping |
| Q42270692 | Differential effects of 9-cis and all-trans retinoic acid on the induction of retinoic acid receptor-beta and cellular retinoic acid-binding protein II in human neuroblastoma cells |
| Q34108090 | Differentiating agents in pediatric malignancies: retinoids in neuroblastoma. |
| Q41334613 | Differentiation, differentiation/gene therapy and cancer |
| Q54147247 | Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL. |
| Q33728384 | E2F1 impairs all-trans retinoic acid-induced osteogenic differentiation of osteosarcoma via promoting ubiquitination-mediated degradation of RARα. |
| Q31858549 | Effects of retinoic acid and sodium butyrate on gene expression, histone acetylation and inhibition of proliferation of melanoma cells |
| Q42002274 | Effects of retinoic acid isomers on apoptosis and enzymatic antioxidant system in human breast cancer cells |
| Q33815859 | Endogenous liver carcinogenesis in the rat. |
| Q39940476 | Enhancement of docetaxel-induced cytotoxicity and apoptosis by all-trans retinoic acid (ATRA) through downregulation of survivin (BIRC5), MCL-1 and LTbeta-R in hormone- and drug resistant prostate cancer cell line, DU-145. |
| Q40891228 | Evidence of epigenetic changes affecting the chromatin state of the retinoic acid receptor beta2 promoter in breast cancer cells |
| Q40631484 | Expression of Sec61 alpha in F9 and P19 teratocarcinoma cells after retinoic acid treatment. |
| Q41313042 | Expression of multidrug resistance in response to differentiation in the K562 human leukaemia cell line |
| Q28552301 | Fenretinide (4-HPR) Targets Caspase-9, ERK 1/2 and the Wnt3a/β-Catenin Pathway in Medulloblastoma Cells and Medulloblastoma Cell Spheroids |
| Q35675265 | First chemical feature-based pharmacophore modeling of potent retinoidal retinoic acid metabolism blocking agents (RAMBAs): identification of novel RAMBA scaffolds. |
| Q92508824 | Future Aspects of CDK5 in Prostate Cancer: From Pathogenesis to Therapeutic Implications |
| Q30908456 | Genetic selection for modulators of a retinoic-acid-responsive reporter in human cells |
| Q52073704 | HINT predictive analysis of binding between retinol binding protein and hydrophobic ligands. |
| Q54612410 | HPV-induced carcinogenesis of the uterine cervix is associated with reduced serum ATRA level. |
| Q24671020 | Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia |
| Q28202210 | Human papilloma virus 16 E6 oncoprotein inhibits retinoic X receptor-mediated transactivation by targeting human ADA3 coactivator |
| Q50755070 | Hypochlorous acid/N-chloramines are naturally produced DNA repair inhibitors. |
| Q24308824 | Identification of a novel human kinesin-related gene (HK2) by the cDNA differential display technique |
| Q59149996 | Imidazoles as potential anticancer agents |
| Q33596422 | Impact of interval and combination therapies on the management of actinic keratosis: review and clinical considerations |
| Q78121372 | Implication of c-Myc in apoptosis induced by the retinoid CD437 in human lung carcinoma cells |
| Q34405484 | In vivo analysis of the molecular genetics of acute promyelocytic leukemia |
| Q33739259 | In vivo analysis of the molecular pathogenesis of acute promyelocytic leukemia in the mouse and its therapeutic implications |
| Q41501304 | In vivo modulation of several anticancer agents by beta-carotene |
| Q73868477 | Induction of apoptosis in human non-small cell lung carcinoma cells by the novel synthetic retinoid CD437 |
| Q35590462 | Induction of differentiation in HL60 cells by the reduction of extrachromosomally amplified c-myc |
| Q28304393 | Inhibition of plasma membrane NADH oxidase activity and growth of HeLa cells by natural and synthetic retinoids |
| Q36613829 | Inhibitory effects of retinoic acid metabolism blocking agents (RAMBAs) on the growth of human prostate cancer cells and LNCaP prostate tumour xenografts in SCID mice. |
| Q34977383 | Interferon alpha plus 13-cis-retinoic acid modulation of BCL-2 plus paclitaxel for recurrent small-cell lung cancer (SCLC): an Eastern Cooperative Oncology Group study (E6501). |
| Q33382828 | Is there a role for all-trans retinoic acid in combination with recombinant erythropoetin in myelodysplastic syndromes? A report on 59 cases |
| Q78169779 | Leukemia: the sophisticated subversion of hematopoiesis by nuclear receptor oncoproteins |
| Q73158655 | Long-term effects of fenretinide on retinal function |
| Q51559437 | Long-term follow-up of larynx leukoplakia under treatment with retinyl palmitate. |
| Q34055317 | Mechanisms of all-trans retinoic acid-induced differentiation of acute promyelocytic leukemia cells |
| Q41098628 | Mitochondrial proliferation and paradoxical membrane depolarization during terminal differentiation and apoptosis in a human colon carcinoma cell line |
| Q36293028 | Modulation of the insulin-like growth factor-I system by N-(4-hydroxyphenyl)-retinamide in human breast cancer cell lines. |
| Q41140205 | Molecular and cellular biomarkers for field cancerization and multistep process in head and neck tumorigenesis |
| Q38344182 | Mutational Analysis Reveals That All-trans-retinoic acid, 9-cis-Retinoic acid, and Antagonist Interact with Distinct Binding Determinants of RARα |
| Q38876796 | Novel all trans-retinoic Acid derivatives: cytotoxicity, inhibition of cell cycle progression and induction of apoptosis in human cancer cell lines. |
| Q73669289 | Novel retinoic acid receptor alpha agonists: syntheses and evaluation of pyrazole derivatives |
| Q41170814 | Nutritional issues in cancer management |
| Q70747413 | Oncology |
| Q55052293 | Overexpression of midkine in pancreatic duct adenocarcinomas induced by N-Nitrosobis(2-oxopropyl)amine in hamsters and their cell lines. |
| Q33388447 | Phase I trial of ATRA-IV and Depakote in patients with advanced solid tumor malignancies |
| Q34739064 | Phase I trial of alpha-tocopherol effects on 13-cis-retinoic acid toxicity |
| Q40786097 | Phase II evaluation of paclitaxel, alpha-interferon, and cis-retinoic acid in advanced renal cell carcinoma |
| Q58212247 | Phase II study of liarozole in advanced non-small cell lung cancer |
| Q62267752 | Phase II trial of 13-cis-retinoic acid plus interferon-α in recurrent head and neck cancer |
| Q48772536 | Positive impact of retinyl palmitate in leukoplakia of the larynx |
| Q40434039 | Progress against cancer |
| Q35198453 | Progress in lung cancer chemoprevention |
| Q71697156 | Protection against malignant conversion in SENCAR mouse skin by all trans retinoic acid: inhibition of the ras p21-processing enzyme farnesyltransferase and Ha-ras p21 membrane localization |
| Q36462605 | Pseudotumor cerebri presenting with visual failure in promyelocytic leukemia: a case report |
| Q24316899 | RAR agonists stimulate SOX9 gene expression in breast cancer cell lines: evidence for a role in retinoid-mediated growth inhibition |
| Q40764926 | RB2/p130 ectopic gene expression in neuroblastoma stem cells: evidence of cell-fate restriction and induction of differentiation |
| Q35906240 | RXRalpha-null F9 embryonal carcinoma cells are resistant to the differentiation, anti-proliferative and apoptotic effects of retinoids |
| Q43605304 | Redifferentiation therapy in brain tumors: long-lasting complete regression of glioblastomas and an anaplastic astrocytoma under long term 1-alpha-hydroxycholecalciferol |
| Q39721558 | Regulation of apoptosis-related molecules by synergistic combination of all-trans retinoic acid and zoledronic acid in hormone-refractory prostate cancer cell lines |
| Q48908980 | Resolution of recurrent malignant ganglioglioma after treatment with cis-retinoic acid |
| Q40360219 | Response of human rhabdomyosarcoma cell lines to retinoic acid: relationship with induction of differentiation and retinoic acid sensitivity |
| Q33940204 | Rethinking the secondary prevention of superficial bladder cancer: is there a role for retinoids? |
| Q36495910 | Retinoic Acid Induces Apoptosis of Prostate Cancer DU145 Cells through Cdk5 Overactivation |
| Q38355307 | Retinoic acid increases expression of the calcium-binding protein S100P in human gastric cancer cells |
| Q35782377 | Retinoic acid induces cells cultured from oral squamous cell carcinomas to become anti-angiogenic. |
| Q34533496 | Retinoic acid inhibition of ex vivo human immunodeficiency virus-associated apoptosis of peripheral blood cells |
| Q44062544 | Retinoic acid modulates the ability of macrophages to participate in the induction of the angiogenic phenotype in head and neck squamous cell carcinoma |
| Q40608539 | Retinoic acid receptor alpha and retinoid-X receptor-specific agonists synergistically target telomerase expression and induce tumor cell death. |
| Q39711207 | Retinoic acid receptor alpha mediates growth inhibition by retinoids in rat pancreatic carcinoma DSL-6A/C1 cells |
| Q41043448 | Retinoic acid regulatory pathways, chromosomal translocations, and acute promyelocytic leukemia |
| Q77157769 | Retinoic acid-induced apoptosis is prevented by serum albumin and enhanced by Lipiodol in human hepatoma Hep3B cells |
| Q40833676 | Retinoic acid-induced apoptotic pathway in T-cell lymphoma: Identification of four groups of genes with differential biological functions |
| Q41157399 | Retinoic acid-induced transcriptional modulation of the human interferon-gamma promoter. |
| Q34476968 | Retinoid therapy of childhood cancer. |
| Q35184993 | Retinoid therapy of high-risk neuroblastoma. |
| Q40903852 | Retinoid-interferon therapy of solid tumors |
| Q34866703 | Retinoids in combination therapies for the treatment of cancer: mechanisms and perspectives |
| Q30464615 | Retinoids in the treatment of glioma: a new perspective |
| Q77333785 | Secondary leukemias induced by topoisomerase-targeted drugs |
| Q34580753 | Selective estrogen receptor modulators (SERMs) and retinoids in breast cancer chemoprevention |
| Q73064605 | Suppression of in vitro maintenance of non-promyelocytic myeloid leukemia clonogenic cells by all-trans retinoic acid: modulating effects of dihydroxylated vitamin D3, alpha interferon and 'stem cell factor' |
| Q70635879 | Synergistic inhibition of human rhabdomyosarcoma cells by sodium phenylacetate and Tretinoin |
| Q43608756 | Syntheses and evaluation of quinoline derivatives as novel retinoic acid receptor alpha antagonists |
| Q43649728 | Synthesis and biological activity of glycosyl conjugates of N-(4-hydroxyphenyl)retinamide. |
| Q47691456 | Systemic treatment of neoplastic conditions with retinoids |
| Q73316240 | Tamoxifen and fenretinide in women with metastatic breast cancer |
| Q34348279 | Targeting apoptosis in prostate cancer |
| Q41126028 | The efficacy of 9-cis retinoic acid in experimental models of cancer. |
| Q40839068 | The emerging role of retinoids and retinoic acid metabolism blocking agents in the treatment of cancer |
| Q36561262 | The receptor-DNA complex determines the retinoid response: a mechanism for the diversification of the ligand signal |
| Q40941739 | The role of human melanoma cell ICAM-1 expression on lymphokine activated killer cell-mediated lysis, and the effect of retinoic acid |
| Q42548848 | The treatment of recurrent cerebral gliomas with all-trans-retinoic acid (tretinoin) |
| Q34718479 | Therapeutic uses of antioxidant liposomes |
| Q80326603 | Therapeutic uses of antioxidant liposomes |
| Q34290301 | Transcription therapy for cancer |
| Q42044447 | Treatment of melanoma cells with the synthetic retinoid CD437 induces apoptosis via activation of AP-1 in vitro, and causes growth inhibition in xenografts in vivo |
| Q71846014 | Treatment of unresectable recurrent head and neck carcinoma with 13-cis-retinoic acid and interferon-alpha. A phase II study |
| Q36136230 | Trial of isotretinoin and calcitriol monitored by CA 125 in patients with ovarian cancer |
| Q43989025 | Tumor prevention by 9-cis-retinoic acid in the N-nitroso-N-methylurea model of mammary carcinogenesis is potentiated by the pineal hormone melatonin |
| Q34028770 | Unconventional therapies for cancer: 5. Vitamins A, C and E. The Task Force on Alternative Therapies of the Canadian Breast Cancer Research Initiative. |
| Q40757455 | Up-regulation of acid sphingomyelinase during retinoic acid-induced myeloid differentiation of NB4, a human acute promyelocytic leukemia cell line |
| Q39570650 | Valproic acid: growth inhibition of head and neck cancer by induction of terminal differentiation and senescence. |
| Q33975839 | Vitamin A and cancer |
| Q42933092 | Vitamin A supplementation for different periods alters rat vascular redox parameters. |
| Q73251594 | Vitamin D and 9-cis retinoic acid: an efficient partnership for the induction of myelomonocytic cell growth inhibition and differentiation |
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