Evidence of epigenetic changes affecting the chromatin state of the retinoic acid receptor beta2 promoter in breast cancer cells

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Evidence of epigenetic changes affecting the chromatin state of the retinoic acid receptor beta2 promoter in breast cancer cells is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1039422578
P356DOI10.1038/SJ.ONC.1203456
P698PubMed publication ID10734315
P5875ResearchGate publication ID12582528

P2093author name stringS Sukumar
A T Ferguson
N Sacchi
R Orlandi
E Sironi
S Subramanyan
S M Sirchia
P2860cites workIdentification of a retinoic acid responsive element in the retinoic acid receptor beta geneQ24300919
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complexQ24324026
CpG methylation, chromatin structure and gene silencing-a three-way connectionQ24533302
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islandsQ24631957
CpG-rich islands and the function of DNA methylationQ28131800
Genomic organization of the human retinoic acid receptor beta 2Q28212852
Mouse and human retinoic acid receptor beta 2 promoters: sequence comparison and localization of retinoic acid responsivenessQ28236548
Role of the histone deacetylase complex in acute promyelocytic leukaemiaQ28263534
Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancerQ29615066
Fusion proteins of the retinoic acid receptor-alpha recruit histone deacetylase in promyelocytic leukaemiaQ29616211
DNA methylation and chromatin modification.Q33632335
Histone deacetylase directs the dominant silencing of transcription in chromatin: association with MeCP2 and the Mi-2 chromodomain SWI/SNF ATPaseQ33671506
Retinoid receptors in health and disease: co-regulators and the chromatin connectionQ33707446
Relationships between chromatin organization and DNA methylation in determining gene expressionQ33765668
Retinoids in cancer therapyQ36032204
Retinoic acid receptor beta mediates the growth-inhibitory effect of retinoic acid by promoting apoptosis in human breast cancer cellsQ36557548
Distinct retinoid X receptor-retinoic acid receptor heterodimers are differentially involved in the control of expression of retinoid target genes in F9 embryonal carcinoma cellsQ36568500
Retinoid-induced chromatin structure alterations in the retinoic acid receptor beta2 promoterQ36573538
A histone deacetylase inhibitor potentiates retinoid receptor action in embryonal carcinoma cellsQ36592145
Core histone hyperacetylation co-maps with generalized DNase I sensitivity in the chicken beta-globin chromosomal domain.Q37631005
Retinoid-dependent in vitro transcription mediated by the RXR/RAR heterodimerQ38301241
Trichostatin A and trapoxin: novel chemical probes for the role of histone acetylation in chromatin structure and functionQ40547910
Signal relay by retinoic acid receptors alpha and beta in the retinoic acid-induced expression of insulin-like growth factor-binding protein-3 in breast cancer cellsQ40949122
Activation of the retinoic acid receptor beta gene by 5-aza-2'-deoxycytidine in human DLD-1 colon carcinoma cellsQ41139729
DNA methylation models histone acetylationQ44585032
DNA methylation affects the formation of active chromatinQ44614953
Demethylation of the progesterone receptor CpG island is not required for progesterone receptor gene expressionQ47684706
Structure of the human retinoic acid receptor beta 1 gene.Q48057964
Different ligand responsiveness of human retinoic-acid-receptor beta-gene transcription in tumorigenic and non-tumorigenic cervical-carcinoma-derived cell lines is mediated through a large retinoic-acid-response domainQ48062012
Promoter architecture, cofactors, and orphan receptors contribute to cell-specific activation of the retinoic acid receptor beta2 promoter.Q52182194
Therapeutic targeting of transcription in acute promyelocytic leukemia by use of an inhibitor of histone deacetylase.Q54117344
Distinct interactions of PML-RARalpha and PLZF-RARalpha with co-repressors determine differential responses to RA in APL.Q54147247
Absence of microsatellite instability in breast carcinomas with both p53 and c-erbB-2 alterationsQ61910329
Retinoic acid nuclear receptor beta inhibits breast carcinoma anchorage independent growthQ71825050
Retinoic acid receptor expression abnormalities in lung cancer: important clues or major obstacles?Q73337245
Repression of transactivation of the retinoic acid receptor beta2 promoter in human breast cancer cellsQ77598277
P433issue12
P407language of work or nameEnglishQ1860
P921main subjecttretinoinQ29417
P304page(s)1556-1563
P577publication date2000-03-01
P1433published inOncogeneQ1568657
P1476titleEvidence of epigenetic changes affecting the chromatin state of the retinoic acid receptor beta2 promoter in breast cancer cells
P478volume19

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cites work (P2860)
Q336129625-Aza-2-deoxycytidine and trichostatin A increase COUP-TFII expression in antiestrogen-resistant breast cancer cell lines
Q33880963A DNA methyltransferase inhibitor and all-trans retinoic acid reduce oral cavity carcinogenesis induced by the carcinogen 4-nitroquinoline 1-oxide
Q39833989A modified protocol for bisulfite genomic sequencing of difficult samples.
Q54355290Aberrant methylation of cyclooxygenase-2 in breast cancer patients.
Q82539025Accumulation of DNA methylation is associated with tumor stage in gastric cancer
Q43839577Allelic loss of chromosome 3p24 correlates with tumor progression rather than with retinoic acid receptor beta2 expression in breast carcinoma
Q39956276Allelic methylation bias of the RARB2 tumor suppressor gene promoter in cancer.
Q37903910An overview of the molecular pathology of head and neck cancer, and its clinical implications.
Q40453415Analysis of methylation-sensitive transcriptome identifies GADD45a as a frequently methylated gene in breast cancer.
Q24816725Antimetastatic gene expression profiles mediated by retinoic acid receptor beta 2 in MDA-MB-435 breast cancer cells
Q34709370Assessment of DNA methylation status in early stages of breast cancer development
Q53721508Association of folate and other one-carbon related nutrients with hypermethylation status and expression of RARB, BRCA1, and RASSF1A genes in breast cancer patients.
Q28345689Biallelic inactivation of retinoic acid receptor beta2 gene by epigenetic change in breast cancer
Q37536680Blocking the PAH2 domain of Sin3A inhibits tumorigenesis and confers retinoid sensitivity in triple negative breast cancer
Q38356593CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells
Q24806085Chemically induced DNA hypomethylation in breast carcinoma cells detected by the amplification of intermethylated sites
Q35108777Chemoprevention of Tumors: The Role of RAR-Beta
Q36918202Combined Treatment with Epigenetic, Differentiating, and Chemotherapeutic Agents Cooperatively Targets Tumor-Initiating Cells in Triple-Negative Breast Cancer
Q35863615Comparative cytotoxicity of artemisinin and cisplatin and their interactions with chlorogenic acids in MCF7 breast cancer cells
Q37155719CpG island tumor suppressor promoter methylation in non-BRCA-associated early mammary carcinogenesis
Q34220062DNA hypermethylation and histone hypoacetylation of the HLTF gene are associated with reduced expression in gastric carcinoma
Q34770599DNA methylation and breast carcinogenesis.
Q44970194DNA methylation control of tissue polarity and cellular differentiation in the mammary epithelium
Q34274795DNA methylation of RASSF1A, HIN‐1, RAR‐β, Cyclin D2 and Twist in in situ and invasive lobular breast carcinoma
Q34446604DNA methylation of genes linked to retinoid signaling in squamous cell carcinoma of the esophagus: DNA methylation of CRBP1 and TIG1 is associated with tumor stage
Q34447242DNA methylation of genes linked with retinoid signaling in gastric carcinoma: expression of the retinoid acid receptor beta, cellular retinol-binding protein 1, and tazarotene-induced gene 1 genes is associated with DNA methylation
Q34544990DNA methylation of nuclear receptor genes--possible role in malignancy
Q96340779DNA methylation patterns of RAR-β2 and RASSF1A gene promoters in FNAB samples from Greek population with benign or malignant breast lesions
Q33403253Derangement of a factor upstream of RARalpha triggers the repression of a pleiotropic epigenetic network
Q73852496Detection of breast cancer cells in ductal lavage fluid by methylation-specific PCR
Q38306563Development of a novel approach for breast cancer prediction and early detection using minimally invasive procedures and molecular analysis: how cytomorphology became a breast cancer risk predictor
Q43785798Differential effects of chromosome 3p deletion on the expression of the putative tumor suppressor RAR beta and on retinoid resistance in human squamous carcinoma cells
Q44124486Distinct promoter hypermethylation of p16INK4a, CDH1, and RAR-beta in intestinal, diffuse-adherent, and diffuse-scattered type gastric carcinomas
Q34557361Dominant negative retinoic acid receptor initiates tumor formation in mice
Q44733985Downregulation of gelsolin and retinoic acid receptor beta expression in gastric cancer tissues through histone deacetylase 1.
Q55007013Downregulation of histone demethylase JMJD1C inhibits colorectal cancer metastasis through targeting ATF2.
Q38364206Downstream codons in the retinoic acid receptor beta -2 and beta -4 mRNAs initiate translation of a protein isoform that disrupts retinoid-activated transcription
Q24794407Ductal approaches to assessment and management of women at high risk for developing breast cancer
Q41888823Epigenetic changes during hematopoietic cell granulocytic differentiation--comparative analysis of primary CD34+ cells, KG1 myeloid cells and mature neutrophils
Q34334842Epigenetic downregulation of the retinoic acid receptor-beta2 gene in breast cancer.
Q35014402Epigenetic priming of AML blasts for all-trans retinoic acid-induced differentiation by the HDAC class-I selective inhibitor entinostat
Q37024069Epigenetic regulation as a new target for breast cancer therapy
Q34725003Epigenetic silencing of cellular retinol-binding proteins in nasopharyngeal carcinoma
Q36856318Epigenetic targeting in breast cancer: therapeutic impact and future direction
Q37078784Epigenomics and breast cancer
Q37310981Familial and racial determinants of tumour suppressor genes promoter hypermethylation in breast tissues from healthy women.
Q35749369Gene promoter hypermethylation in ductal lavage fluid from healthy BRCA gene mutation carriers and mutation-negative controls
Q41664067Histone Deacetylases as New Therapeutic Targets in Triple-negative Breast Cancer: Progress and Promises
Q40488993Identification of novel RARbeta2 transcript variants with short 5'-UTRs in normal and cancerous breast epithelial cells
Q34150792Impaired retinoic acid (RA) signal leads to RARbeta2 epigenetic silencing and RA resistance
Q59804079Induction of cell cycle arrest and inflammatory genes by combined treatment with epigenetic, differentiating, and chemotherapeutic agents in triple-negative breast cancer
Q37626858Inhibition of PRC2 histone methyltransferase activity increases TRAIL-mediated apoptosis sensitivity in human colon cancer cells
Q51776655Isolation and comparative study of cell-free nucleic acids from human urine.
Q39531093Knockdown of RARB2 identifies a dual role in cancer
Q44588824Loss of expression of tropomyosin-1, a novel class II tumor suppressor that induces anoikis, in primary breast tumors
Q59504124Loss of heterozygosity of the NOS3 dinucleotide repeat marker in atherosclerotic plaques of human carotid arteries
Q38450120Methylation Profiling of Benign and Malignant Breast Lesions and Its Application to Cytopathology
Q74234880Methylation of conserved CpG sites neighboring the beta retinoic acid response element may mediate retinoic acid receptor beta gene silencing in MCF-7 breast cancer cells
Q34267943Methylation patterns in cell-free plasma DNA reflect removal of the primary tumor and drug treatment of breast cancer patients
Q36745391Molecular pathways: current role and future directions of the retinoic acid pathway in cancer prevention and treatment
Q35653852Phase I study of the histone deacetylase inhibitor entinostat in combination with 13-cis retinoic acid in patients with solid tumours
Q36607318Polycyclic aromatic hydrocarbon (PAH)-DNA adducts and breast cancer: modification by gene promoter methylation in a population-based study
Q37606299Prognostic and therapeutic potential of nuclear receptors in head and neck squamous cell carcinomas
Q36622838Prognostic significance of gene-specific promoter hypermethylation in breast cancer patients
Q91669240Promoter Methylation Status of the Retinoic Acid Receptor-Beta 2 Gene in Breast Cancer Patients: A Case Control Study and Systematic Review
Q57890923Promoter Methylation and Silencing of the Retinoic Acid Receptor- Gene in Lung Carcinomas
Q35801560Promoter Methylation of the Retinoic Acid Receptor Beta2 (RARβ2) Is Associated with Increased Risk of Breast Cancer: A PRISMA Compliant Meta-Analysis
Q40356013RAR-mediated epigenetic control of the cytochrome P450 Cyp26a1 in embryocarcinoma cells
Q91727275Retinoic Acid Receptors in Acute Myeloid Leukemia Therapy
Q89510543Retinoic Acids in the Treatment of Most Lethal Solid Cancers
Q39929691Retinoic acid receptor beta2 re-expression and growth inhibition in thyroid carcinoma cell lines after 5-aza-2'-deoxycytidine treatment.
Q35867945Retinoic acid reduces migration of human breast cancer cells: role of retinoic acid receptor beta
Q38240617Retinoic acid signaling in cancer: The parable of acute promyelocytic leukemia
Q38331050Retinoic acid targets DNA-methyltransferases and histone deacetylases during APL blast differentiation in vitro and in vivo.
Q35009313Retinoid, retinoic acid receptor beta and breast cancer
Q34498098Retinoids and their receptors in cancer development and chemoprevention
Q28081010Retinoids induce cellular senescence in breast cancer cells by RAR-β dependent and independent pathways: Potential clinical implications (Review)
Q37809078Retinoids, Retinoic Acid Receptors, and Cancer
Q35053227Selective retinoids and rexinoids in cancer therapy and chemoprevention
Q34000367Synergistic chromatin repression of the tumor suppressor gene RARB in human prostate cancers
Q42446700The N-terminal of the estrogen receptor (ERalpha) mediates transcriptional cross-talk with the retinoic acid receptor in human breast cancer cells
Q26772035The Role of Sulforaphane in Epigenetic Mechanisms, Including Interdependence between Histone Modification and DNA Methylation
Q35053948The biology of breast carcinoma
Q35623919The influence of one-carbon metabolism on gene promoter methylation in a population-based breast cancer study.
Q37197352The methylation of the TSC2 promoter underlies the abnormal growth of TSC2 angiomyolipoma-derived smooth muscle cells
Q43675656The role of epigenetic modifications in retinoic acid receptor beta2 gene expression in human prostate cancers
Q36932335Toll-like receptor 3 (TLR3) activation induces microRNA-dependent reexpression of functional RARβ and tumor regression
Q58862234Total synthesis of the proposed structures of the DNA methyl transferase inhibitors peyssonenynes, and structural revision of peyssonenyne B
Q37699371Tracing anti-cancer and cancer-promoting actions of all-trans retinoic acid in breast cancer to a RARα epigenetic mechanism of mammary epithelial cell fate
Q39570650Valproic acid: growth inhibition of head and neck cancer by induction of terminal differentiation and senescence.

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