| P50 | author | Gerrit J Poelarends | Q88902935 |
| P2093 | author name string | Bert-Jan Baas | |
| | Mehran Rahimi | |
| | Edzard M Geertsema | |
| | Harshwardhan Poddar | |
| | Jan-Ytzen van der Meer | |
| P2860 | cites work | Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme | Q27683542 |
| | Evidence for the formation of an enamine species during aldol and Michael-type addition reactions promiscuously catalyzed by 4-oxalocrotonate tautomerase | Q27698082 |
| | The 4-oxalocrotonate tautomerase family of enzymes: how nature makes new enzymes using a beta-alpha-beta structural motif | Q28202879 |
| | Physically associated enzymes produce and metabolize 2-hydroxy-2,4-dienoate, a chemically unstable intermediate formed in catechol metabolism via meta cleavage in Pseudomonas putida | Q28354983 |
| | Expanding the substrate scope of enzymes: combining mutations obtained by CASTing | Q33247423 |
| | Addressing the numbers problem in directed evolution | Q33345289 |
| | Evolutionary potential of (beta/alpha)8-barrels: functional promiscuity produced by single substitutions in the enolase superfamily | Q33967159 |
| | Designed divergent evolution of enzyme function | Q33993746 |
| | Enzyme promiscuity: a mechanistic and evolutionary perspective | Q34021669 |
| | The chemical versatility of the beta-alpha-beta fold: catalytic promiscuity and divergent evolution in the tautomerase superfamily | Q34095040 |
| | Improving enzyme properties: when are closer mutations better? | Q36113206 |
| | Enzyme promiscuity: evolutionary and mechanistic aspects. | Q36580808 |
| | Protein engineers turned evolutionists | Q37020095 |
| | Recent progress in stereoselective synthesis with aldolases | Q37673484 |
| | Mutational effects and the evolution of new protein functions. | Q37773157 |
| | Novel carbon-carbon bond formations for biocatalysis | Q37847523 |
| | Recent advances in the study of enzyme promiscuity in the tautomerase superfamily | Q38104684 |
| | Recent developments in enzyme promiscuity for carbon-carbon bond-forming reactions | Q38322861 |
| | Using mutability landscapes of a promiscuous tautomerase to guide the engineering of enantioselective Michaelases | Q38917445 |
| | Promiscuous catalysis of asymmetric Michael-type additions of linear aldehydes to β-nitrostyrene by the proline-based enzyme 4-oxalocrotonate tautomerase | Q43778627 |
| | Biocatalytic Michael-type additions of acetaldehyde to nitroolefins with the proline-based enzyme 4-oxalocrotonate tautomerase yielding enantioenriched γ-nitroaldehydes. | Q54784192 |
| | The Catalytic Asymmetric Aldol Reaction. | Q55033822 |
| | Chemical and enzymic ketonization of 2-hydroxymuconate, a conjugated enol | Q56815356 |
| | Directed evolution of enantioselective enzymes: iterative cycles of CASTing for probing protein-sequence space | Q56899243 |
| P433 | issue | 13 | |
| P304 | page(s) | 1225-1228 | |
| P577 | publication date | 2016-05-30 | |
| P1433 | published in | ChemBioChem | Q634395 |
| P1476 | title | Mutations Closer to the Active Site Improve the Promiscuous Aldolase Activity of 4-Oxalocrotonate Tautomerase More Effectively than Distant Mutations | |
| P478 | volume | 17 | |