SIX2 and CITED1, markers of nephronic progenitor self-renewal, remain active in primitive elements of Wilms' tumor

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SIX2 and CITED1, markers of nephronic progenitor self-renewal, remain active in primitive elements of Wilms' tumor is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.JPEDSURG.2012.03.034
P932PMC publication ID3377935
P698PubMed publication ID22703800
P5875ResearchGate publication ID227164237

P50authorJanene PierceQ124037589
P2093author name stringAlan O Perantoni
Mark P de Caestecker
Andrew J Murphy
Christian de Caestecker
Harold N Lovvorn
James R Anderson
Chase Taylor
P2860cites workThe transcriptional activity of CITED1 is regulated by phosphorylation in a cell cycle-dependent mannerQ24297950
Wilms' tumorigenesis is altered by misexpression of the transcriptional co-activator, CITED1Q24298969
CITED1 expression in Wilms' tumor and embryonic kidneyQ24337902
STAT1 activation regulates proliferation and differentiation of renal progenitorsQ24338667
Gene expression in Wilms' tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transitionQ24685187
ELR+-CXC chemokines and their receptors in early metanephric developmentQ28571457
Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidneyQ28586205
Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney developmentQ28592487
Cited1 and Cited2 are differentially expressed in the developing kidney but are not required for nephrogenesisQ28593339
Wilms tumor chromatin profiles highlight stem cell properties and a renal developmental networkQ33961864
Wilms tumor genetics: mutations in WT1, WTX, and CTNNB1 account for only about one-third of tumorsQ34010180
Wilms' tumorQ34013130
Nuclear accumulation of beta-catenin protein indicates activation of wnt signaling in chemically induced rat nephroblastomasQ34346138
Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylationQ34428960
Wilms' tumours: about tumour suppressor genes, an oncogene and a chameleon geneQ35095712
Defining and redefining the nephron progenitor populationQ35294035
Wilms' tumour: connecting tumorigenesis and organ development in the kidneyQ36234726
Pax-2 is a DNA-binding protein expressed in embryonic kidney and Wilms tumorQ36826291
Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia.Q37235452
High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor populationQ37356678
Early organogenesis of the kidneyQ39611879
Serine-phosphorylated STAT1 is a prosurvival factor in Wilms' tumor pathogenesisQ40262816
Nuclear accumulation of beta-catenin protein in Wilms' tumoursQ50335613
Expression of insulin-like growth factor-II mRNA in fetal kidney and Wilms' tumor. An in situ hybridization studyQ69358949
Accumulation of malignant renal stem cells is associated with epigenetic changes in normal renal progenitor genesQ81243903
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)1239-1249
P577publication date2012-06-01
P1433published inJournal of Pediatric SurgeryQ15761821
P1476titleSIX2 and CITED1, markers of nephronic progenitor self-renewal, remain active in primitive elements of Wilms' tumor
P478volume47

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cites work (P2860)
Q37639483Aberrant activation, nuclear localization, and phosphorylation of Yes-associated protein-1 in the embryonic kidney and Wilms tumor.
Q87206471Assessment of promoter methylation and expression of SIX2 as a diagnostic and prognostic biomarker in Wilms' tumor
Q38559338Biomarkers to detect Wilms tumors in pediatric patients: where are we now?
Q37660299CITED1 confers stemness to Wilms tumor and enhances tumorigenic responses when enriched in the nucleus.
Q36520712CITED1 expression in liver development and hepatoblastoma
Q34917145Cited1 deficiency suppresses intestinal tumorigenesis.
Q36597449Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators
Q90167841Disruption of Robo2-Baiap2 integrated signaling drives cystic disease
Q64916990Expression and clinical significance of p73 in Wilms tumor in children.
Q36052678Genetic and chromosomal alterations in Kenyan Wilms Tumor
Q37146691Genetic variation frequencies in Wilms' tumor: A meta-analysis and systematic review
Q34717946Homeoprotein Six2 promotes breast cancer metastasis via transcriptional and epigenetic control of E-cadherin expression
Q55420112Modeling Renal Disease "On the Fly".
Q30449310Molecular characterization of Wilms' tumor from a resource-constrained region of sub-Saharan Africa
Q64120594Molecular determinants of WNT9b responsiveness in nephron progenitor cells
Q35028775SIX2 Effects on Wilms Tumor Biology
Q36297071TGF-β-Induced Transcription Sustains Amoeboid Melanoma Migration and Dissemination.
Q92783038The FGF, TGFβ and WNT axis Modulate Self-renewal of Human SIX2+ Urine Derived Renal Progenitor Cells
Q38960059miR181c promotes apoptosis and suppresses proliferation of metanephric mesenchyme cells by targeting Six2 in vitro.

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