Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia.

scientific article published on 24 October 2007

Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YDBIO.2007.10.014
P932PMC publication ID2699557
P698PubMed publication ID18061157
P5875ResearchGate publication ID5787354

P50authorE. Michelle Southard-SmithQ63436814
P2093author name stringScott Boyle
H Scott Baldwin
Kelly J Chandler
Douglas P Mortlock
Mark de Caestecker
Andrew Misfeldt
Karen K Deal
P2860cites workThe cellular basis of kidney developmentQ36527712
Molecular insights into segmentation along the proximal-distal axis of the nephron.Q36643537
Efficient studies of long-distance Bmp5 gene regulation using bacterial artificial chromosomes.Q37110776
Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domainsQ38343320
Kinetics of tamoxifen-regulated Cre activity in mice using a cartilage-specific CreER(T) to assay temporal activity windows along the proximodistal limb skeletonQ40300014
Bmp2 transcription in osteoblast progenitors is regulated by a distant 3' enhancer located 156.3 kilobases from the promoterQ41975562
Msg1 and Mrg1, founding members of a gene family, show distinct patterns of gene expression during mouse embryogenesis.Q48038317
Morphometric index of the developing murine kidneyQ50792365
FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons.Q52043165
The structural organization of the mouse kidney.Q53744582
Metanephric mesenchyme contains multipotent stem cells whose fate is restricted after inductionQ68183495
Inductive interaction of embryonic tissues after dissociation and reaggregationQ78424105
Ligand-activated site-specific recombination in miceQ24600193
Generalized lacZ expression with the ROSA26 Cre reporter strainQ27860837
Cre recombinase: the universal reagent for genome tailoringQ28145361
The metanephric blastema differentiates into collecting system and nephron epithelia in vitroQ28291337
Murine homolog of SALL1 is essential for ureteric bud invasion in kidney developmentQ28509612
Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidneyQ28586205
Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney developmentQ28587889
Cited1 and Cited2 are differentially expressed in the developing kidney but are not required for nephrogenesisQ28593339
Cre recombinase: The universal reagent for genome tailoringQ29028530
A highly efficient recombineering-based method for generating conditional knockout mutationsQ29615157
A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNAQ29615197
Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouseQ29620355
Size matters: use of YACs, BACs and PACs in transgenic animalsQ34220676
Nephron induction revisited: from caps to condensatesQ34468245
An extensive 3' regulatory region controls expression of Bmp5 in specific anatomical structures of the mouse embryoQ34602453
Role of transcriptional networks in coordinating early events during kidney developmentQ36499689
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)234-245
P577publication date2007-10-24
P1433published inDevelopmental BiologyQ3025402
P1476titleFate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia
P478volume313

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cites work (P2860)
Q48220898A Pdgf-cCreERT2 knock-in mouse model for tracing PDGF-C cell lineages during development
Q47744942A Sall1-NuRD interaction regulates multipotent nephron progenitors and is required for loop of Henle formation
Q34416207A p53-Pax2 pathway in kidney development: implications for nephrogenesis.
Q38536413A regulatory program for excretory system regeneration in planarians
Q35901240A synthetic niche for nephron progenitor cells
Q37424512Advances in early kidney specification, development and patterning
Q38165796Alagille, Notch, and robustness: why duplicating systems does not ensure redundancy
Q50622854An integrated pipeline for the multidimensional analysis of branching morphogenesis.
Q35673700Atlas of Cellular Dynamics during Zebrafish Adult Kidney Regeneration
Q33383689Atlas of gene expression in the developing kidney at microanatomic resolution
Q38161819BMP signaling and its modifiers in kidney development
Q37849623BMP signaling in the nephron progenitor niche
Q28594843Bmp2 and Bmp4 exert opposing effects in hypoxic pulmonary hypertension
Q31133744Bmp7 maintains undifferentiated kidney progenitor population and determines nephron numbers at birth
Q26822802Bone morphogenetic protein signaling in nephron progenitor cells
Q28513261C-myc as a modulator of renal stem/progenitor cell population
Q28590640Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development
Q35108850Chromatin-based mechanisms of renal epithelial differentiation
Q89967686Combining Kidney Organoids and Genome Editing Technologies for a Better Understanding of Physiopathological Mechanisms of Renal Diseases: State of the Art
Q28083531Concise Review: Understanding the Renal Progenitor Cell Niche In Vivo to Recapitulate Nephrogenesis In Vitro
Q37774975Concise review: Kidney stem/progenitor cells: differentiate, sort out, or reprogram?
Q36392093Concurrent BMP7 and FGF9 signalling governs AP-1 function to promote self-renewal of nephron progenitor cells
Q49959847Conserved and Divergent Features of Human and Mouse Kidney Organogenesis.
Q49959878Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney
Q49959864Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning
Q37641781Control of the bone morphogenetic protein 7 gene in developmental and adult life
Q35294035Defining and redefining the nephron progenitor population
Q39242443Development and Diseases of the Collecting Duct System.
Q28069920Development of the Mammalian Kidney
Q37655968Dicer function is required in the metanephric mesenchyme for early kidney development
Q36597449Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators
Q42247713Direct Isolation and Characterization of Human Nephron Progenitors
Q34350833Direct transcriptional reprogramming of adult cells to embryonic nephron progenitors
Q39313624Directed differentiation of human pluripotent cells to ureteric bud kidney progenitor-like cells
Q50684875Down-regulated Six2 by knockdown of neurofibromin results in apoptosis of metanephric mesenchyme cells in vitro.
Q26782631Each niche has an actor: multiple stem cell niches in the preterm kidney
Q84167464Endocardial cells are a distinct endothelial lineage derived from Flk1+ multipotent cardiovascular progenitors
Q35234669Enteric neuron imbalance and proximal dysmotility in ganglionated intestine of the Sox10Dom/+ Hirschsprung mouse model.
Q33765462Essential roles of epithelial bone morphogenetic protein signaling during prostatic development.
Q41018789Evidence of In Vitro Preservation of Human Nephrogenesis at the Single-Cell Level
Q33495588Expression of stem cell markers in the human fetal kidney
Q35534606FGF/EGF signaling regulates the renewal of early nephron progenitors during embryonic development
Q36036048FGF9 and FGF20 maintain the stemness of nephron progenitors in mice and man.
Q35181459Fibroblast growth factor receptor-Frs2α signaling is critical for nephron progenitors
Q38247213From ureteric bud to the first glomeruli: genes, mediators, kidney alterations.
Q34661724GDNF/Ret signaling and renal branching morphogenesis: From mesenchymal signals to epithelial cell behaviors
Q28513713GLI3 repressor controls nephron number via regulation of Wnt11 and Ret in ureteric tip cells
Q37280957Generation of the podocyte and tubular components of an amniote kidney: timing of specification and a role for Wnt signaling
Q26996583Genetic controls and cellular behaviors in branching morphogenesis of the renal collecting system
Q37234873Genome-wide analysis of the p53 gene regulatory network in the developing mouse kidney
Q39242434Growth Factor Regulation in the Nephrogenic Zone of the Developing Kidney
Q33541613Hepatocyte nuclear factor 4 alpha is related to survival of the condensed mesenchyme in the developing mouse kidney
Q37356678High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor population
Q50155675Highly tamoxifen-inducible principal-cell-specific Cre mice with complete fidelity in cell specificity and no leakiness
Q38531972Human Urine as a Noninvasive Source of Kidney Cells
Q34469453Identification of a multipotent self-renewing stromal progenitor population during mammalian kidney organogenesis
Q33840861Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways
Q37237128Identification of human nephron progenitors capable of generation of kidney structures and functional repair of chronic renal disease.
Q39242463Imaging, Analysing and Interpreting Branching Morphogenesis in the Developing Kidney
Q39329153Immunohistochemical and electronmicroscopic features of mesenchymal-to-epithelial transition in human developing, postnatal and nephrotic podocytes
Q35586384In vivo clonal analysis reveals lineage-restricted progenitor characteristics in mammalian kidney development, maintenance, and regeneration.
Q42646690Inducible gene manipulations in serotonergic neurons
Q34615730Induction and patterning of the metanephric nephron
Q37226803Inheritance of susceptibility to induction of nephroblastomas in the Noble rat.
Q34549454Inhibition of Pax2 Transcription Activation with a Small Molecule that Targets the DNA Binding Domain
Q36191159Intrinsic Age-Dependent Changes and Cell-Cell Contacts Regulate Nephron Progenitor Lifespan
Q37778484Kidney development: two tales of tubulogenesis
Q38162641Kidney injury, stem cells and regeneration
Q90424222Kidney organoids: accurate models or fortunate accidents
Q37728655Kidney regeneration
Q39372173Lats1/2 Regulate Yap/Taz to Control Nephron Progenitor Epithelialization and Inhibit Myofibroblast Formation
Q35568242Lineage tracing of neuromesodermal progenitors reveals novel Wnt-dependent roles in trunk progenitor cell maintenance and differentiation
Q37684913Lineage-tracing methods and the kidney
Q89295025Loss of Dis3l2 partially phenocopies Perlman syndrome in mice and results in up-regulation of Igf2 in nephron progenitor cells
Q64059604MAPK/ERK Signaling in Regulation of Renal Differentiation
Q35663843Maintenance of Mouse Nephron Progenitor Cells in Aggregates with Gamma-Secretase Inhibitor
Q38996786Making new kidneys: On the road from science fiction to science fact.
Q35902711Mammalian kidney development: principles, progress, and projections
Q92565699Manipulating the Mouse Genome Using Recombineering
Q53073697Marked interindividual variability in renal maturation of preterm infants: lessons from autopsy.
Q26825793Mechanisms of gene activation and repression by Pax proteins in the developing kidney
Q36706151Mi-2/NuRD is required in renal progenitor cells during embryonic kidney development
Q102071892Molecular detection of maturation stages in the developing kidney
Q64120594Molecular determinants of WNT9b responsiveness in nephron progenitor cells
Q36737769Molecular regulation of kidney development
Q34207078Morphogenesis and molecular mechanisms involved in human kidney development.
Q47674940Myc cooperates with β-catenin to drive gene expression in nephron progenitor cells.
Q37218003Nephron Progenitor But Not Stromal Progenitor Cells Give Rise to Wilms Tumors in Mouse Models with β-Catenin Activation or Wt1 Ablation and Igf2 Upregulation
Q51852105Nephron formation adopts a novel spatial topology at cessation of nephrogenesis.
Q39107139Nephron number, hypertension, and CKD: physiological and genetic insight from humans and animal models
Q29037394Nephron organoids derived from human pluripotent stem cells model kidney development and injury
Q47292164Nephron progenitor cell death elicits a limited compensatory response associated with interstitial expansion in the neonatal kidney
Q35208718Notch pathway activation can replace the requirement for Wnt4 and Wnt9b in mesenchymal-to-epithelial transition of nephron stem cells
Q33817814Notch signaling is required for the formation of mesangial cells from a stromal mesenchyme precursor during kidney development.
Q35184825Ontogeny of the Kidney and Renal Developmental Markers in the Rhesus Monkey (Macaca Mulatta)
Q28594297Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney
Q43135180Paraxial mesoderm contributes stromal cells to the developing kidney
Q33904019Patterning a complex organ: branching morphogenesis and nephron segmentation in kidney development
Q38544732Pluripotent Stem Cells to Rebuild a Kidney: The Lymph Node as a Possible Developmental Niche
Q37140603Progress in gene targeting: using mutant mice to study renal function and disease
Q36105769RNA-Seq defines novel genes, RNA processing patterns and enhancer maps for the early stages of nephrogenesis: Hox supergenes
Q52723218Reduced Abd-B Hox function during kidney development results in lineage infidelity.
Q50517291Regulation of Nephron Progenitor Cell Self-Renewal by Intermediary Metabolism.
Q59335813Regulation of Renal Differentiation by Trophic Factors
Q35693864Renal organogenesis: what can it tell us about renal repair and regeneration?
Q28067647Renal progenitors: Roles in kidney disease and regeneration
Q27006064Renal stem cells: fact or science fiction?
Q34496903Renal stromal miRNAs are required for normal nephrogenesis and glomerular mesangial survival.
Q92283031Reporter-based fate mapping in human kidney organoids confirms nephron lineage relationships and reveals synchronous nephron formation
Q38768831Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development
Q37995895Reprogramming the kidney: a novel approach for regeneration
Q30703127Retinoic Acid Signaling Coordinates Macrophage-Dependent Injury and Repair after AKI.
Q36712738Role for compartmentalization in nephron progenitor differentiation
Q36041333SIX2 and CITED1, markers of nephronic progenitor self-renewal, remain active in primitive elements of Wilms' tumor
Q28594787Sall1 balances self-renewal and differentiation of renal progenitor cells
Q34427626Sall1 maintains nephron progenitors and nascent nephrons by acting as both an activator and a repressor
Q37868851Selecting the optimal cell for kidney regeneration: fetal, adult or reprogrammed stem cells.
Q34341652Single cell dissection of early kidney development: multilineage priming
Q28592487Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development
Q104468736Sox10-cre BAC transgenes reveal temporal restriction of mesenchymal cranial neural crest and identify glandular Sox10 expression
Q28504550TGF-β signaling plays an essential role in the growth and maintenance of intervertebral disc tissue
Q50743818Tbx18 expression demarcates multipotent precursor populations in the developing urogenital system but is exclusively required within the ureteric mesenchymal lineage to suppress a renal stromal fate.
Q34302418Tetracycline inducible gene manipulation in serotonergic neurons
Q33615861The contribution of Notch1 to nephron segmentation in the developing kidney is revealed in a sensitized Notch2 background and can be augmented by reducing Mint dosage.
Q39000495The contribution of branching morphogenesis to kidney development and disease.
Q37158061The genetics and epigenetics of kidney development
Q26829303The kidney and planar cell polarity
Q30580163The number of fetal nephron progenitor cells limits ureteric branching and adult nephron endowment
Q38283627The regulation of apoptosis in kidney development: implications for nephron number and pattern?
Q38560470Therapeutic use of human renal progenitor cells for kidney regeneration
Q39242429Tissue-Specific Functions of p53 During Kidney Development
Q38940497Understanding kidney morphogenesis to guide renal tissue regeneration.
Q40974247Urine of Preterm Neonates as a Novel Source of Kidney Progenitor Cells.
Q42376448WT1 Is Necessary for the Proliferation and Migration of Cells of Renin Lineage Following Kidney Podocyte Depletion.
Q37795569WT1 and kidney progenitor cells
Q33757338Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation
Q35228883p53 Enables metabolic fitness and self-renewal of nephron progenitor cells
Q35679310β-Catenin and K-RAS synergize to form primitive renal epithelial tumors with features of epithelial Wilms' tumors
Q38993024β-catenin activation in a novel liver progenitor cell type is sufficient to cause hepatocellular carcinoma and hepatoblastoma
Q34726881β-catenin causes renal dysplasia via upregulation of Tgfβ2 and Dkk1
Q91105928β-catenin regulates the formation of multiple nephron segments in the mouse kidney

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