Concise Review: Understanding the Renal Progenitor Cell Niche In Vivo to Recapitulate Nephrogenesis In Vitro

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Concise Review: Understanding the Renal Progenitor Cell Niche In Vivo to Recapitulate Nephrogenesis In Vitro is …
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P356DOI10.5966/SCTM.2015-0104
P932PMC publication ID4675508
P698PubMed publication ID26494782

P2093author name stringC. Mari
P. Winyard
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Wnt/beta-catenin signaling regulates nephron induction during mouse kidney developmentQ28506499
Osr1 acts downstream of and interacts synergistically with Six2 to maintain nephron progenitor cells during kidney organogenesisQ28506958
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Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital systemQ28511083
Role of fibroblast growth factor receptors 1 and 2 in the metanephric mesenchymeQ28511352
TGF beta 2, LIF and FGF2 cooperate to induce nephrogenesisQ28580797
Inactivation of FGF8 in early mesoderm reveals an essential role in kidney developmentQ28585034
Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidneyQ28586205
Foxd1-dependent signals control cellularity in the renal capsule, a structure required for normal renal developmentQ28586643
Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney developmentQ28590640
Stromal-epithelial crosstalk regulates kidney progenitor cell differentiationQ28592110
c-kit delineates a distinct domain of progenitors in the developing kidneyQ28592476
Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney developmentQ28592487
Cited1 and Cited2 are differentially expressed in the developing kidney but are not required for nephrogenesisQ28593339
Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidneyQ28594297
Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networksQ28594605
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Induced pluripotent stem cells generated without viral integrationQ29614343
Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptorQ29616189
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Fgfr1 and the IIIc isoform of Fgfr2 play critical roles in the metanephric mesenchyme mediating early inductive events in kidney development.Q30500205
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Differentiated kidney epithelial cells repair injured proximal tubule.Q34038540
OFD1, the gene mutated in oral-facial-digital syndrome type 1, is expressed in the metanephros and in human embryonic renal mesenchymal cellsQ34178550
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Basic fibroblast growth factor can mediate the early inductive events in renal developmentQ34359827
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How do mesangial and endothelial cells form the glomerular tuft?Q34733658
Isolation and characterization of progenitor-like cells from human renal proximal tubulesQ34760590
Intrinsic epithelial cells repair the kidney after injuryQ34765013
Repair of injured proximal tubule does not involve specialized progenitorsQ35022127
Interaction between FGF and BMP signaling pathways regulates development of metanephric mesenchymeQ35199256
FGF/EGF signaling regulates the renewal of early nephron progenitors during embryonic developmentQ35534606
Ureteric bud controls multiple steps in the conversion of mesenchyme to epithelia.Q35588769
Progenitor cells in the kidney: biology and therapeutic perspectives.Q35836416
Projecting the United States ESRD population: issues regarding treatment of patients with ESRD.Q35856752
FGF9 and FGF20 maintain the stemness of nephron progenitors in mice and man.Q36036048
The cellular basis of kidney developmentQ36527712
Apoptosis in metanephric developmentQ36532293
Role for compartmentalization in nephron progenitor differentiationQ36712738
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Hoxd11 specifies a program of metanephric kidney development within the intermediate mesoderm of the mouse embryo.Q36967093
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Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia.Q37235452
High-resolution gene expression analysis of the developing mouse kidney defines novel cellular compartments within the nephron progenitor populationQ37356678
The PAX2 tanscription factor is expressed in cystic and hyperproliferative dysplastic epithelia in human kidney malformationsQ37357742
BMP7 promotes proliferation of nephron progenitor cells via a JNK-dependent mechanismQ37385501
Cell and molecular biology of kidney developmentQ37555042
Proximal tubular cells contain a phenotypically distinct, scattered cell population involved in tubular regenerationQ37632721
Compartmentalized organization: a common and required feature of stem cell niches?Q37739680
WT1 and kidney progenitor cellsQ37795569
Glomerular number and size variability and risk for kidney diseaseQ37811790
Patterning and early cell lineage decisions in the developing kidney: the role of Pax genesQ37827422
Human nephron number: implications for health and diseaseQ37878424
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Nephron reconstitution from pluripotent stem cellsQ38282187
Reactivation of NCAM1 defines a subpopulation of human adult kidney epithelial cells with clonogenic and stem/progenitor propertiesQ38485570
Isolation of renal progenitor cells from adult human kidneyQ38585185
Mouse embryonic stem cell-derived embryoid bodies generate progenitors that integrate long term into renal proximal tubules in vivoQ40137981
Microarray interrogation of human metanephric mesenchymal cells highlights potentially important molecules in vivo.Q40229890
In vitro differentiation of murine embryonic stem cells toward a renal lineageQ40244111
Transient gene expression by nonintegrating lentiviral vectorsQ40300665
Ureteric bud cells secrete multiple factors, including bFGF, which rescue renal progenitors from apoptosisQ41075031
Conditioned medium from a rat ureteric bud cell line in combination with bFGF induces complete differentiation of isolated metanephric mesenchyme.Q41146792
Mesenchymal to epithelial conversion in rat metanephros is induced by LIF.Q42614278
Characterization of renal progenitors committed toward tubular lineage and their regenerative potential in renal tubular injuryQ42649770
In vitro induction of the pronephric duct in Xenopus explantsQ43952064
Directing human embryonic stem cell differentiation towards a renal lineage generates a self-organizing kidneyQ45178758
PKH(high) cells within clonal human nephrospheres provide a purified adult renal stem cell populationQ45754901
Nephrogenic factors promote differentiation of mouse embryonic stem cells into renal epitheliaQ46788585
FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons.Q52043165
A molecular and genetic analysis of renalglomerular capillary development.Q52196841
The timing and sequence of events in the development of the human urinary system during the embryonic period proper.Q54434464
Isolation and Characterization of Kidney-Derived Stem CellsQ56777906
Hypoxia modulates the undifferentiated phenotype of human renal inner medullary CD133+ progenitors through Oct4/miR-145 balanceQ58831468
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)1463-71
P577publication date2015-12-01
P1433published inStem Cells Translational MedicineQ26842216
P1476titleConcise Review: Understanding the Renal Progenitor Cell Niche In Vivo to Recapitulate Nephrogenesis In Vitro
P478volume4