Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development

scientific journal article

Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1242/DEV.057646
P3181OpenCitations bibliographic resource ID1873856
P932PMC publication ID3050658
P698PubMed publication ID21350016

P50authorChuo ChenQ38325681
P2093author name stringLawrence Lum
Thomas J. Carroll
Amrita Das
Courtney M. Karner
Guillermo Oliver
Michelle Self
Zhendong Ma
P2860cites workTankyrase inhibition stabilizes axin and antagonizes Wnt signallingQ24316697
Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin geneQ24529898
A molecular mechanism for the effect of lithium on developmentQ24629067
WebGestalt: an integrated system for exploring gene sets in various biological contextsQ24813284
Wnt/beta-catenin signaling regulates nephron induction during mouse kidney developmentQ28506499
A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eyeQ28508005
Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4Q28508296
Wnt9b signaling regulates planar cell polarity and kidney tubule morphogenesisQ28510389
Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital systemQ28511083
Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial developmentQ28513519
Inactivation of FGF8 in early mesoderm reveals an essential role in kidney developmentQ28585034
Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidneyQ28586205
Distinct and sequential tissue-specific activities of the LIM-class homeobox gene Lim1 for tubular morphogenesis during kidney developmentQ28587889
A role for Wnt signalling in self-renewal of haematopoietic stem cellsQ28592213
Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney developmentQ28592487
The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in Wingless processingQ28616128
Regulation of cerebral cortical size by control of cell cycle exit in neural precursorsQ29615158
Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancerQ29616163
Apoptosis and morphology in mouse embryos by confocal laser scanning microscopyQ30775069
Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cellsQ33891944
Nephron number in patients with primary hypertensionQ34530304
CTNNB1 mutations and overexpression of Wnt/beta-catenin target genes in WT1-mutant Wilms' tumorsQ35103587
Fate mapping using Cited1-CreERT2 mice demonstrates that the cap mesenchyme contains self-renewing progenitor cells and gives rise exclusively to nephronic epithelia.Q37235452
BMP7 promotes proliferation of nephron progenitor cells via a JNK-dependent mechanismQ37385501
beta-catenin/TCF/Lef controls a differentiation-associated transcriptional program in renal epithelial progenitorsQ38299235
Cessation of renal morphogenesis in miceQ40007459
Tankyrase is necessary for canonical Wnt signaling during kidney developmentQ42529744
Mesenchymal to epithelial conversion in rat metanephros is induced by LIF.Q42614278
Glomerular number and size in relation to age, kidney weight, and body surface in normal manQ44090511
beta-Catenin signals regulate cell growth and the balance between progenitor cell expansion and differentiation in the nervous systemQ44472635
A stereological study of glomerular number and volume: preliminary findings in a multiracial study of kidneys at autopsyQ44514215
Nuclear accumulation of beta-catenin protein in Wilms' tumoursQ50335613
FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons.Q52043165
Epithelial-specific Cre/lox recombination in the developing kidney and genitourinary tract.Q54303657
Mutational activation of the beta-catenin proto-oncogene is a common event in the development of Wilms' tumorsQ57413414
Induction of Early Stages of Kidney Tubule Differentiation by Lithium IonsQ64447213
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectCatenin (cadherin associated protein), beta 1Q14902827
Wingless-type MMTV integration site family, member 4Q15321888
Sine oculis-related homeobox 2Q21981887
Wingless-type MMTV integration site family, member 9BQ21992813
P304page(s)1247–1257
P577publication date2011-04-01
P1433published inDevelopmentQ3025404
P1476titleCanonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development
P478volume138

Reverse relations

cites work (P2860)
Q47744942A Sall1-NuRD interaction regulates multipotent nephron progenitors and is required for loop of Henle formation
Q38744723A holey pursuit: lumen formation in the developing kidney
Q34416207A p53-Pax2 pathway in kidney development: implications for nephrogenesis.
Q38827528A strategy for generating kidney organoids: Recapitulating the development in human pluripotent stem cells.
Q35901240A synthetic niche for nephron progenitor cells
Q27323376A universal vector for high-efficiency multi-fragment recombineering of BACs and knock-in constructs
Q38165796Alagille, Notch, and robustness: why duplicating systems does not ensure redundancy
Q87206471Assessment of promoter methylation and expression of SIX2 as a diagnostic and prognostic biomarker in Wilms' tumor
Q34211767Atmin mediates kidney morphogenesis by modulating Wnt signaling.
Q26822802Bone morphogenetic protein signaling in nephron progenitor cells
Q37660299CITED1 confers stemness to Wilms tumor and enhances tumorigenic responses when enriched in the nucleus.
Q95841364Canonical WNT/β-Catenin Signaling Activated by WNT9b and RSPO2 Cooperation Regulates Facial Morphogenesis in Mice
Q50225238Cap mesenchyme cell swarming during kidney development is influenced by attraction, repulsion, and adhesion to the ureteric tip.
Q91714300Cellular and Molecular Mechanisms of Kidney Development: From the Embryo to the Kidney Organoid
Q28083531Concise Review: Understanding the Renal Progenitor Cell Niche In Vivo to Recapitulate Nephrogenesis In Vitro
Q36392093Concurrent BMP7 and FGF9 signalling governs AP-1 function to promote self-renewal of nephron progenitor cells
Q52610909Conditional ablation of the prorenin receptor in nephron progenitor cells results in developmental programming of hypertension.
Q34389279Conditional expression of Wnt9b in Six2-positive cells disrupts stomach and kidney function
Q49959878Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney
Q49959864Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning
Q30660201Deducing the stage of origin of Wilms' tumours from a developmental series of Wt1-mutant mice
Q30464083Defective photoreceptor phagocytosis in a mouse model of enhanced S-cone syndrome causes progressive retinal degeneration
Q90102234Deletion of hypoxia-responsive microRNA-210 results in a sex-specific decrease in nephron number
Q28069920Development of the Mammalian Kidney
Q39218625Developmental origins and functions of stromal cells in the normal and diseased mammalian kidney
Q37655968Dicer function is required in the metanephric mesenchyme for early kidney development
Q36597449Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators
Q52715978Disparate levels of beta-catenin activity determine nephron progenitor cell fate.
Q99406913Emerging Roles of Wnt Ligands in Human Colorectal Cancer
Q30301009Epigenetic States of nephron progenitors and epithelial differentiation
Q36146662Expression Pattern of Axin2 During Chicken Development
Q31039711Expression of Wnt signaling components during Xenopus pronephros development
Q40843427Expression of Wnt9, TCTP, and Bmp1/Tll in sea cucumber visceral regeneration.
Q42029713Eya1 interacts with Six2 and Myc to regulate expansion of the nephron progenitor pool during nephrogenesis
Q35534606FGF/EGF signaling regulates the renewal of early nephron progenitors during embryonic development
Q36036048FGF9 and FGF20 maintain the stemness of nephron progenitors in mice and man.
Q37398464FOXD1 promotes nephron progenitor differentiation by repressing decorin in the embryonic kidney
Q35181459Fibroblast growth factor receptor-Frs2α signaling is critical for nephron progenitors
Q90563988Functional roles of Grainyhead-like transcription factors in renal development and disease
Q39242434Growth Factor Regulation in the Nephrogenic Zone of the Developing Kidney
Q47280626Haploinsufficiency for the Six2 gene increases nephron progenitor proliferation promoting branching and nephron number
Q35213401Histone deacetylase (HDAC) activity is critical for embryonic kidney gene expression, growth, and differentiation.
Q35178908Histone deacetylase 1 and 2 regulate Wnt and p53 pathways in the ureteric bud epithelium
Q39123933Histone signature of metanephric mesenchyme cell lines
Q92432580Human kidney organoids: progress and remaining challenges
Q34469453Identification of a multipotent self-renewing stromal progenitor population during mammalian kidney organogenesis
Q36119224Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis
Q37655842In situ histone landscape of nephrogenesis
Q90057497In utero exposure to maternal diabetes impairs nephron progenitor differentiation
Q34615730Induction and patterning of the metanephric nephron
Q91650498Inhibition of GSK3 Represses the Expression of Retinoic Acid Synthetic Enzyme ALDH1A2 via Wnt/β-Catenin Signaling in WiT49 Cells
Q35111241Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron
Q89047768Interplay between the renin-angiotensin system, the canonical WNT/β-catenin pathway and PPARγ in hypertension
Q36191159Intrinsic Age-Dependent Changes and Cell-Cell Contacts Regulate Nephron Progenitor Lifespan
Q41830151In Vitro Propagation and Branching Morphogenesis from Single Ureteric Bud Cells
Q26829595Is Wilms tumor a candidate neoplasia for treatment with WNT/β-catenin pathway modulators?--A report from the renal tumors biology-driven drug development workshop
Q64120239Kidney micro-organoids in suspension culture as a scalable source of human pluripotent stem cell-derived kidney cells
Q90424222Kidney organoids: accurate models or fortunate accidents
Q52659230Lithium induces mesenchymal-epithelial differentiation during human kidney development by activation of the Wnt signalling system.
Q52730232Lkb1 deficiency confers glutamine dependency in polycystic kidney disease.
Q92155409Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors
Q47220125Low birth weight is associated with impaired murine kidney development and function
Q35663843Maintenance of Mouse Nephron Progenitor Cells in Aggregates with Gamma-Secretase Inhibitor
Q38996786Making new kidneys: On the road from science fiction to science fact.
Q35902711Mammalian kidney development: principles, progress, and projections
Q38260184Mdm2 is required for maintenance of the nephrogenic niche
Q36706151Mi-2/NuRD is required in renal progenitor cells during embryonic kidney development
Q36995482Modeling renal progenitors - defining the niche
Q64120594Molecular determinants of WNT9b responsiveness in nephron progenitor cells
Q47674940Myc cooperates with β-catenin to drive gene expression in nephron progenitor cells.
Q26785918Nephron Patterning: Lessons from Xenopus, Zebrafish, and Mouse Studies
Q51852105Nephron formation adopts a novel spatial topology at cessation of nephrogenesis.
Q61810164Nephron progenitor commitment is a stochastic process influenced by cell migration
Q35208718Notch pathway activation can replace the requirement for Wnt4 and Wnt9b in mesenchymal-to-epithelial transition of nephron stem cells
Q37425842Notch signaling promotes nephrogenesis by downregulating Six2.
Q39242453Origin and Function of the Renal Stroma in Health and Disease
Q28506958Osr1 acts downstream of and interacts synergistically with Six2 to maintain nephron progenitor cells during kidney organogenesis
Q44863401Parallel waves of inductive signaling and mesenchyme maturation regulate differentiation of the chick mesonephros
Q89243186Pericytes in the renal vasculature: roles in health and disease
Q59104245Planar Cell Polarity Pathway in Kidney Development and Function
Q37949488Planar cell polarity in kidney development and disease
Q28603277Postembryonic Nephrogenesis and Persistence of Six2-Expressing Nephron Progenitor Cells in the Reptilian Kidney
Q36201559Preferential Propagation of Competent SIX2+ Nephronic Progenitors by LIF/ROCKi Treatment of the Metanephric Mesenchyme
Q38723947Prorenin receptor controls renal branching morphogenesis via Wnt/β-catenin signaling
Q36494933Prorenin receptor is critical for nephron progenitors
Q93175769R-spondin signalling is essential for the maintenance and differentiation of mouse nephron progenitors
Q38136556Recreating kidney progenitors from pluripotent cells
Q50517291Regulation of Nephron Progenitor Cell Self-Renewal by Intermediary Metabolism.
Q51185911Regulation of kidney development by the Mdm2/Mdm4-p53 axis.
Q50607500Renal developmental defects resulting from in utero hypoxia are associated with suppression of ureteric β-catenin signaling.
Q38724083Renal dysplasia in the neonate
Q27006064Renal stem cells: fact or science fiction?
Q34496903Renal stromal miRNAs are required for normal nephrogenesis and glomerular mesangial survival.
Q38768831Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development
Q36712738Role for compartmentalization in nephron progenitor differentiation
Q38731327Role of hypoxia during nephrogenesis.
Q35028775SIX2 Effects on Wilms Tumor Biology
Q28594787Sall1 balances self-renewal and differentiation of renal progenitor cells
Q34427626Sall1 maintains nephron progenitors and nascent nephrons by acting as both an activator and a repressor
Q50515204Selective In Vitro Propagation of Nephron Progenitors Derived from Embryos and Pluripotent Stem Cells.
Q52717951Sex differences in transcriptomic profiles in aged kidney cells of renin lineage.
Q90149509Simple 3D culture of dissociated kidney mesenchyme mimics nephron progenitor niche and facilitates nephrogenesis Wnt-independently
Q28594605Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks
Q28592110Stromal-epithelial crosstalk regulates kidney progenitor cell differentiation
Q35213366Stromally expressed β-catenin modulates Wnt9b signaling in the ureteric epithelium
Q50743818Tbx18 expression demarcates multipotent precursor populations in the developing urogenital system but is exclusively required within the ureteric mesenchymal lineage to suppress a renal stromal fate.
Q26770522The Good and Bad of β-Catenin in Kidney Development and Renal Dysplasia
Q35453913The PI3K pathway balances self-renewal and differentiation of nephron progenitor cells through β-catenin signaling
Q39000495The contribution of branching morphogenesis to kidney development and disease.
Q26829303The kidney and planar cell polarity
Q35173260The yin and yang of kidney development and Wilms' tumors
Q39242429Tissue-Specific Functions of p53 During Kidney Development
Q38331807Towards a quantitative model of kidney morphogenesis
Q39388260Transcriptional mechanisms coordinating tight junction assembly during epithelial differentiation.
Q90644144Transcriptional regulation of cell shape during organ morphogenesis
Q33624868TβRII Regulates the Proliferation of Metanephric Mesenchyme Cells through Six2 In Vitro
Q38940497Understanding kidney morphogenesis to guide renal tissue regeneration.
Q35228902WT1 targets Gas1 to maintain nephron progenitor cells by modulating FGF signals
Q47699592Wnt Signaling in Kidney Development and Disease.
Q26999700Wnt and planar cell polarity signaling in cystic renal disease
Q64081000Wnt signaling mediates new nephron formation during zebrafish kidney regeneration
Q39316445Wnt signaling, a novel pathway regulating blood pressure? State of the art review
Q59792108Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment
Q34491576Wnt4 is essential to normal mammalian lung development
Q50320046Wnt8a expands the pool of embryonic kidney progenitors in zebrafish.
Q35893650Wnt9b-dependent FGF signaling is crucial for outgrowth of the nasal and maxillary processes during upper jaw and lip development
Q35228883p53 Enables metabolic fitness and self-renewal of nephron progenitor cells
Q91105928β-catenin regulates the formation of multiple nephron segments in the mouse kidney

Search more.