Eya1 interacts with Six2 and Myc to regulate expansion of the nephron progenitor pool during nephrogenesis (scientific article published on 24 November 2014)

EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear

Q28505753

Six1 is required for the early organogenesis of mammalian kidney

Q28510085

Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system

Q28511083

Six1 regulates Grem1 expression in the metanephric mesenchyme to initiate branching morphogenesis

Q28512287

Dachshund and eyes absent proteins form a complex and function synergistically to induce ectopic eye development in Drosophila

Q74037490

C-myc as a modulator of renal stem/progenitor cell population

Q28513261

Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney

Q28586205

Eya1-deficient mice lack ears and kidneys and show abnormal apoptosis of organ primordia

Q28587212

Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development

Q28590640

Differential regulation of two sets of mesonephric tubules by WT-1

Q28592223

Six2 defines and regulates a multipotent self-renewing nephron progenitor population throughout mammalian kidney development

Q28592487

Osr1 expression demarcates a multi-potent population of intermediate mesoderm that undergoes progressive restriction to an Osr1-dependent nephron progenitor compartment within the mammalian kidney

Q28594297

Six2 and Wnt regulate self-renewal and commitment of nephron progenitors through shared gene regulatory networks

Q28594605

FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation

Q29616127

Wnt breakers in colon cancer

Q33197185

c-Myc proteolysis by the ubiquitin-proteasome pathway: stabilization of c-Myc in Burkitt's lymphoma cells

Q33962550

Kidney development: regulatory molecules crucial to both mice and men.

Q34043202

Germ-layer and lineage-restricted stem/progenitors regenerate the mouse digit tip

Q34210638

N-myc controls proliferation, morphogenesis, and patterning of the inner ear

Q35146783

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

Q35204486

The life cycle of C-myc: from synthesis to degradation

Q35910342

New vision from Eyes absent: transcription factors as enzymes.

Q36056189

Making myc.

Q36451343

Role of post-translational modifications in regulating c-Myc proteolysis, transcriptional activity and biological function

Q36580032

Mouse Eya genes are expressed during limb tendon development and encode a transcriptional activation function

Q36632601

Role for compartmentalization in nephron progenitor differentiation

Q36712738

EYA1 phosphatase function is essential to drive breast cancer cell proliferation through cyclin D1.

Q37128230

Eya1 gene dosage critically affects the development of sensory epithelia in the mammalian inner ear.

Q37294806

Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition

Q37328450

The EYA-SO/SIX complex in development and disease

Q38027074

Early organogenesis of the kidney

Q39611879

The Cdk1 complex plays a prime role in regulating N-myc phosphorylation and turnover in neural precursors.

Q40378610

Eya1-Six1 interaction is sufficient to induce hair cell fate in the cochlea by activating Atoh1 expression in cooperation with Sox2.

Q41485484

A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size

Q45118851

Redefining the in vivo origin of metanephric nephron progenitors enables generation of complex kidney structures from pluripotent stem cells

Q46405604

c-Myc regulates mammalian body size by controlling cell number but not cell size

Q47197283

Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors.

Q48123329

Defects in heart and lung development in compound heterozygotes for two different targeted mutations at the N-myc locus.

Q52222479

P433

issue

P407

language of work or name

English

Q1860

P1104

number of pages

P304

page(s)

434-447

P577

publication date

2014-11-24

P1433

published in

Developmental Cell

Q1524277

P1476

title

Eya1 interacts with Six2 and Myc to regulate expansion of the nephron progenitor pool during nephrogenesis

P478

volume

Reverse relations

cites work (P2860)

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P356	DOI	10.1016/J.DEVCEL.2014.10.015
P932	PMC publication ID	4282136
P698	PubMed publication ID	25458011