Mice lacking macrophage 12/15-lipoxygenase are resistant to experimental hypertension

scientific article

Mice lacking macrophage 12/15-lipoxygenase are resistant to experimental hypertension is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPHEART.01120.2011
P932PMC publication ID3378305
P698PubMed publication ID22467300
P5875ResearchGate publication ID223980012

P2093author name stringKathryn M Gauthier
William B Campbell
Tamas Kriska
Cody Cepura
Lawan Siangjong
Devora Magier
P2860cites workRole of arachidonic acid lipoxygenase metabolites in the regulation of vascular toneQ28248514
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A role for the mouse 12/15-lipoxygenase pathway in promoting epithelial wound healing and host defenseQ28508815
Effects of silencing leukocyte-type 12/15-lipoxygenase using short interfering RNAsQ28574130
Reticulocyte 15-lipoxygenase-I is important in acetylcholine-induced endothelium-dependent vasorelaxation in rabbit aortaQ46766143
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Baicalein and 12/15-lipoxygenase in the ischemic brainQ48391844
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Evidence for an initial, thymus independent and a chronic, thymus dependent phase of DOCA and salt hypertension in miceQ67874685
Comparison of antioxidant and nonantioxidant lipoxygenase inhibitors on neutrophil function. Implications for pathogenesis of myocardial reperfusion injuryQ68451746
Bacterial expression, purification and partial characterization of recombinant rabbit reticulocyte 15-lipoxygenaseQ70742571
Rearrangement of 15-hydroperoxy-eicosatetraenoic acid (15-HPETE) during incubations with hemoglobin: a model for platelet lipoxygenase metabolismQ71603332
Identification of the 11,14,15- and 11,12, 15-trihydroxyeicosatrienoic acids as endothelium-derived relaxing factors of rabbit aortaQ77545036
The role of the macrophage in immune regulationQ77675946
Evidence that macrophages are required for T-cell infiltration and rejection of fetal pig pancreas xenografts in nonobese diabetic miceQ77736809
ACh-induced relaxations of rabbit small mesenteric arteries: role of arachidonic acid metabolites and K+Q79873745
A simple method of isolating mouse aortic endothelial cellsQ80379544
cDNA cloning, expression, mutagenesis of C-terminal isoleucine, genomic structure, and chromosomal localizations of murine 12-lipoxygenasesQ28594638
The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholineQ29547539
Critical role of macrophage 12/15-lipoxygenase for atherosclerosis in apolipoprotein E-deficient miceQ30434635
The effects of leukocyte-type 12/15-lipoxygenase on Id3-mediated vascular smooth muscle cell growthQ30434996
12/15-lipoxygenase products induce inflammation and impair insulin signaling in 3T3-L1 adipocytes.Q30435822
The role of 12/15-lipoxygenase in the expression of interleukin-6 and tumor necrosis factor-alpha in macrophagesQ30442352
Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in miceQ30976814
Cloning and expression of an airway epithelial 12-lipoxygenaseQ31115951
Increased levels of 12(S)-HETE in patients with essential hypertensionQ32070260
Lipoxygenases: occurrence, functions, catalysis, and acquisition of substrateQ33710597
Resistance to type 1 diabetes induction in 12-lipoxygenase knockout miceQ33854422
Release of C-type natriuretic peptide accounts for the biological activity of endothelium-derived hyperpolarizing factorQ34331513
12/15-lipoxygenase, oxidative modification of LDL and atherogenesisQ34423069
Inflammation, immunity, and hypertensionQ34528283
Docosahexanoic acid-induced coronary arterial dilation: actions of 17S-hydroxy docosahexanoic acid on K+ channel activityQ34702424
Role of arachidonic acid lipoxygenase metabolites in acetylcholine-induced relaxations of mouse arteriesQ34720342
Elevated endothelial nitric oxide bioactivity and resistance to angiotensin-dependent hypertension in 12/15-lipoxygenase knockout miceQ35083693
Mammalian lipoxygenases: molecular structures and functionsQ35460975
Catalytic consumption of nitric oxide by 12/15- lipoxygenase: inhibition of monocyte soluble guanylate cyclase activationQ36535336
Arachidonic acid metabolites as endothelium-derived hyperpolarizing factorsQ36698020
Effects of cholesterol-tagged small interfering RNAs targeting 12/15-lipoxygenase on parameters of diabetic nephropathy in a mouse model of type 1 diabetesQ36844506
Diverse roles of 2-arachidonoylglycerol in invasion of prostate carcinoma cells: Location, hydrolysis and 12-lipoxygenase metabolism.Q36932469
mRNA silencing in erythroid differentiation: hnRNP K and hnRNP E1 regulate 15-lipoxygenase translation from the 3' end.Q38345852
Arachidonate 15-lipoxygenaseQ41088079
The molecular biology of mammalian lipoxygenases and the quest for eicosanoid functions using lipoxygenase-deficient miceQ41245074
The role of 15-lipoxygenase in atherogenesis: pro- and antiatherogenic actionsQ41497384
Cardiac 12/15 lipoxygenase-induced inflammation is involved in heart failureQ42214940
Elevated expression of 12/15-lipoxygenase and cyclooxygenase-2 in a transgenic mouse model of prostate carcinomaQ42440649
Apamin-sensitive K+ currents mediate arachidonic acid-induced relaxations of rabbit aortaQ42454695
Platelet lipoxygenase in spontaneously hypertensive ratsQ42517063
Absence of 12/15-lipoxygenase expression decreases lipid peroxidation and atherogenesis in apolipoprotein e-deficient miceQ43600849
Interleukin 4 induces transcription of the 15-lipoxygenase I gene in human endothelial cellsQ43607825
12/15-Lipoxygenase gene disruption attenuates atherogenesis in LDL receptor-deficient miceQ43753471
A novel form of platelet-type 12-lipoxygenase mRNA in human vascular smooth muscle cellsQ43771336
Arachidonic and linoleic acid metabolism in mouse intestinal tissue: evidence for novel lipoxygenase activityQ43866791
Selective interleukin-12 synthesis defect in 12/15-lipoxygenase-deficient macrophages associated with reduced atherosclerosis in a mouse model of familial hypercholesterolemiaQ44066949
11,12,15-Trihydroxyeicosatrienoic acid mediates ACh-induced relaxations in rabbit aortaQ44542215
"In vivo" depletion of macrophages by liposome-mediated "suicide".Q44721535
Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice: key role for endothelium-derived hyperpolarizing factor in the regulation of blood pressure in vivo.Q45256231
Interaction between P450 eicosanoids and nitric oxide in the control of arterial tone in miceQ45722244
P433issue11
P921main subjectmacrophageQ184204
hypertensionQ95566669
P304page(s)H2428-38
P577publication date2012-03-30
P1433published inAmerican Journal of Physiology Heart and Circulatory PhysiologyQ3193662
P1476titleMice lacking macrophage 12/15-lipoxygenase are resistant to experimental hypertension
P478volume302

Reverse relations

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