Cytosolic phospholipase A2α is critical for angiotensin II-induced hypertension and associated cardiovascular pathophysiology

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Cytosolic phospholipase A2α is critical for angiotensin II-induced hypertension and associated cardiovascular pathophysiology is …
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scholarly articleQ13442814

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P356DOI10.1161/HYPERTENSIONAHA.114.04803
P932PMC publication ID4359078
P698PubMed publication ID25667212

P2093author name stringJoseph V Bonventre
Anne M Estes
Brett L Jennings
Kafait U Malik
Nayaab S Khan
Xiao R Fang
Chi Young Song
P2860cites workSoluble epoxide hydrolase as a therapeutic target for cardiovascular diseasesQ24597172
Cyclooxygenase-2 inhibitors attenuate angiotensin II-induced oxidative stress, hypertension, and cardiac hypertrophy in ratsQ28174302
20-HETE and blood pressure regulation: clinical implicationsQ28288942
Angiotensin II-induced vascular smooth muscle cell migration and growth are mediated by cytochrome P450 1B1-dependent superoxide generationQ28571898
12/15-Lipoxygenase signaling in the endoplasmic reticulum stress responseQ28593657
The mammalian unfolded protein responseQ29547400
P-450 metabolites of arachidonic acid in the control of cardiovascular functionQ29620578
Specific physiological roles of cytosolic phospholipase A(2) as defined by gene knockoutsQ34083788
Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor toneQ34378188
Properties and regulation of cytosolic phospholipase A2.Q34430575
Calcium dependency of prostaglandin E2 production in rat glomerular mesangial cells. Evidence that protein kinase C modulates the Ca2+-dependent activation of phospholipase A2.Q34557191
The intrarenal renin-angiotensin system: from physiology to the pathobiology of hypertension and kidney disease.Q34690091
Elevated endothelial nitric oxide bioactivity and resistance to angiotensin-dependent hypertension in 12/15-lipoxygenase knockout miceQ35083693
Physiological genomic analysis of the brain renin-angiotensin systemQ35196494
Prostaglandin E-prostanoid4 receptor mediates angiotensin II-induced (pro)renin receptor expression in the rat renal medullaQ35654731
Calcium/calmodulin-dependent protein kinase IIalpha mediates activation of mitogen-activated protein kinase and cytosolic phospholipase A2 in norepinephrine-induced arachidonic acid release in rabbit aortic smooth muscle cellsQ71825158
Contribution of Ras GTPase/MAP kinase and cytochrome P450 metabolites to deoxycorticosterone-salt-induced hypertensionQ73371695
Signal transduction mechanisms involved in angiotensin-(1-7)-stimulated arachidonic acid release and prostanoid synthesis in rabbit aortic smooth muscle cellsQ74064560
ANG II-induced translocation of cytosolic PLA2 to the nucleus in vascular smooth muscle cellsQ74153502
Neural mechanisms in nitric-oxide-deficient hypertensionQ77893931
T regulatory lymphocytes prevent angiotensin II-induced hypertension and vascular injuryQ83288251
Angiotensin II-dependent hypertension requires cyclooxygenase 1-derived prostaglandin E2 and EP1 receptor signaling in the subfornical organ of the brainQ35838537
Reactive oxygen species, vascular oxidative stress, and redox signaling in hypertension: what is the clinical significance?Q35840821
Antihypertensive effects of selective prostaglandin E2 receptor subtype 1 targeting.Q35925625
Disruption of group IVA cytosolic phospholipase A(2) attenuates myocardial ischemia-reperfusion injury partly through inhibition of TNF-α-mediated pathwayQ35994164
Mice lacking macrophage 12/15-lipoxygenase are resistant to experimental hypertensionQ36042687
Role of the T cell in the genesis of angiotensin II induced hypertension and vascular dysfunctionQ36229028
ER stress in the brain subfornical organ mediates angiotensin-dependent hypertensionQ36357920
Cytosolic Phospholipase A2α–deficient Mice Are Resistant to Collagen-induced ArthritisQ36370405
Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular systemQ36548154
Inactivation of the E-prostanoid 3 receptor attenuates the angiotensin II pressor response via decreasing arterial contractility.Q36591447
Mammalian cytochromes P450--importance of tissue specificity.Q36649952
Arachidonic Acid metabolites in the cardiovascular system: the role of lipoxygenase isoforms in atherogenesis with particular emphasis on vascular remodelingQ37037140
Suppression of endoplasmic reticulum stress improves endothelium-dependent contractile responses in aorta of the spontaneously hypertensive ratQ37093720
Phospholipase A2 structure/function, mechanism, and signalingQ37326136
Cyclooxygenase-1 inhibition attenuates angiotensin II-salt hypertension and neurogenic pressor activity in the rat.Q37342183
Cytosolic phospholipase A2 as a mediator of disease pathogenesisQ37774040
Preclinical evaluation of an inhibitor of cytosolic phospholipase A2α for the treatment of asthmaQ39429765
Prostaglandins, prostacyclin, and thromboxanesQ40306987
Essential requirement of cytosolic phospholipase A(2) for stimulation of NADPH oxidase-associated diaphorase activity in granulocyte-like cells.Q40795547
Arthur C. Corcoran Memorial Lecture. The role of eicosanoids in angiotensin-dependent hypertensionQ41695612
Brain-mediated dysregulation of the bone marrow activity in angiotensin II-induced hypertensionQ41882282
Effects of chronic NO synthase inhibition in rats on renin-angiotensin system and sympathetic nervous systemQ42275808
Cytosolic phospholipase A(2)-alpha enhances induction of endoplasmic reticulum stressQ42466944
Renal concentrating defect in mice lacking group IV cytosolic phospholipase A(2).Q42501163
Subcellular localization of prostaglandin-forming cyclooxygenase in Swiss mouse 3T3 fibroblasts by electron microscopic immunocytochemistry.Q42828540
Angiotensin II stimulates phosphorylation of high-molecular-mass cytosolic phospholipase A2 in vascular smooth-muscle cellsQ42833875
Cytosolic phospholipase A2 (cPLA2) regulation of human monocyte NADPH oxidase activity. cPLA2 affects translocation but not phosphorylation of p67(phox) and p47(phox).Q44052605
Endothelin-1-induced arachidonic acid release by cytosolic phospholipase A2 activation in rat vascular smooth muscle via extracellular signal-regulated kinases pathwayQ44082406
Cyclic stretch-induced cPLA2 mediates ERK 1/2 signaling in rabbit proximal tubule cellsQ44724752
Reduction of cPLA2alpha overexpression: an efficient anti-inflammatory therapy for collagen-induced arthritisQ46339671
Targeting the calpain/calpastatin system as a new strategy to prevent cardiovascular remodeling in angiotensin II-induced hypertensionQ46765412
Angiotensin II induces vascular smooth muscle cell replication independent of blood pressureQ47987909
Reduced fertility and postischaemic brain injury in mice deficient in cytosolic phospholipase A2.Q48580352
Red wine polyphenols prevent angiotensin II-induced hypertension and endothelial dysfunction in rats: role of NADPH oxidase.Q50729559
Identification of specific EP receptors responsible for the hemodynamic effects of PGE2.Q52536351
Characterization of murine vasopressor and vasodepressor prostaglandin E(2) receptors.Q52539292
Cytosolic phospholipase A2alpha contributes to blood pressure increases and endothelial dysfunction under chronic NO inhibition.Q53265321
Blood pressure-independent effects in rats with human renin and angiotensinogen genes.Q54062419
Renal prostaglandins and phospholipase A2 in spontaneously hypertensive rats.Q54405993
Role of cytosolic phospholipase A2 in allergic response and parturitionQ59069879
Arachidonic Acid Metabolites Mediate Angiotensin II-Induced NADH/NADPH Oxidase Activity and Hypertrophy in Vascular Smooth Muscle CellsQ63365779
Central effects of prostaglandin E2 on blood pressure and plasma renin activity in rats. Role of the sympathoadrenal system and vasopressinQ67234982
Role of pressor prostanoids in rats with angiotensin II-salt-induced hypertensionQ67922688
Angiotensin II causes vascular hypertrophy in part by a non-pressor mechanismQ70143885
Reactive oxygen production associated with arachidonic acid metabolism by peritoneal macrophagesQ71536778
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)784-792
P577publication date2015-02-09
P1433published inHypertensionQ5958695
P1476titleCytosolic phospholipase A2α is critical for angiotensin II-induced hypertension and associated cardiovascular pathophysiology
P478volume65

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cites work (P2860)
Q89006965Angiotensin II Signal Transduction: An Update on Mechanisms of Physiology and Pathophysiology
Q46374083Antioxidant tempol suppresses heart cytosolic phospholipase A2α stimulated by chronic intermittent hypoxia.
Q47681288Bone marrow-derived cPLA2α contributes to renal fibrosis progression.
Q47859985Brain Cytosolic Phospholipase A2α Mediates Angiotensin II-Induced Hypertension and Reactive Oxygen Species Production in Male Mice
Q90143428Central CYP1B1 (Cytochrome P450 1B1)-Estradiol Metabolite 2-Methoxyestradiol Protects From Hypertension and Neuroinflammation in Female Mice
Q41817139Cytochrome P450 1B1 Contributes to the Development of Angiotensin II-Induced Aortic Aneurysm in Male Apoe(-/-) Mice
Q36573633Cytosolic Phospholipase A2α Is Essential for Renal Dysfunction and End-Organ Damage Associated With Angiotensin II-Induced Hypertension
Q47699621Dipeptidyl Peptidase-4 Inhibition With Saxagliptin Ameliorates Angiotensin II-Induced Cardiac Diastolic Dysfunction in Male Mice
Q36310177Global Prioritization of Disease Candidate Metabolites Based on a Multi-omics Composite Network
Q41097787Nicotinic acetylcholine receptor-mediated protection of the rat heart exposed to ischemia reperfusion.
Q40998803Possible role for brain prostanoid pathways in the development of angiotensin II-salt hypertension in rats

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